CN101816625A - Mild low-stimulation hand sanitizer and preparation method thereof - Google Patents

Mild low-stimulation hand sanitizer and preparation method thereof Download PDF

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Publication number
CN101816625A
CN101816625A CN201010173105A CN201010173105A CN101816625A CN 101816625 A CN101816625 A CN 101816625A CN 201010173105 A CN201010173105 A CN 201010173105A CN 201010173105 A CN201010173105 A CN 201010173105A CN 101816625 A CN101816625 A CN 101816625A
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China
Prior art keywords
stimulation
mild low
handwashing liquid
deionized water
ether
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CN201010173105A
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CN101816625B (en
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李泉清
魏淑芬
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Beijing green umbrella Technology Co.,Ltd.
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BEIJING LUSAN CHEMICAL Co Ltd
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Abstract

The invention relates to a mild low-stimulation hand sanitizer and a preparation method thereof. The mild low-stimulation hand sanitizer is prepared from raw materials of fatty alcohd-polyoxyethlene (9) ether, lauramidopropyl betaine, cocamidopropyl ammonium oxide, alkanolamides of fatty acids, alkyl glucoside, sodium chloride, 1,2-benzoisothiazole-3-one, essence, citric acid monohydrate and deionized water, and is prepared after mild surfactants obtained through screening is compounded with an active substance synthesized by natural corn starch and glucose. The mild low-stimulation hand sanitizer can complete cleaning and moistening the hands at one time, has no toxin and stimulation, and greatly saves the use cost.

Description

Handwashing liquid of a kind of mild low-stimulation and preparation method thereof
Technical field
The present invention relates to chemical field, particularly handwashing liquid of a kind of mild low-stimulation and preparation method thereof.This handwashing liquid contains gentle handguard composition, reduces adversary's stimulation when having cleaning function.
Background technology
For a long time, the cleaning product that is exclusively used in hand rarely has production and selling, and the cleaning product of the usefulness of washing one's hands mainly is fancy soap and soap.After the seventies in last century, handwashing liquid occurs in western countries, because it takes convenience, and no cross infection, no soap scum produces and is easy to flushing, can also increase characteristics such as various functions according to actual needs, enters the commercial market rapidly in the eighties.Before and after China handwashing liquid market started from 2000, average consumption was 1-2 ton/year.Present commercially available handwashing liquid is used for general cleaning more, and handwashing liquid also can be removed the fat on hand skin surface except spot is taken away simultaneously in cleaning process, and cleaning the back hand has drying, uncomfortable sensation such as tight.
In order to solve the existing in prior technology problem, await providing a kind of functional type handwashing liquid, can in the cleaning spot, have additional functions such as moist and handguard.
Summary of the invention
The object of the present invention is to provide a kind of handwashing liquid of mild low-stimulation, the surfactant of the gentleness that this handwashing liquid obtains by screening with composite from native corn starch, the synthetic active matter of glucose after be prepared from; Can once finish cleaning, moistening, and nontoxic, non-stimulated, saved use cost widely.
Another object of the present invention is to provide a kind of preparation method of handwashing liquid of mild low-stimulation.
The objective of the invention is to be achieved through the following technical solutions: a kind of handwashing liquid of mild low-stimulation is prepared from by its ratio of weight and number by following raw material:
Aliphatic alcohol polyethenoxy (9) ether 1.0-5.0
Lauryl amido propyl betaine 3.0-5.0
Cocamidopropyl propyl amide amine-oxides 1.0-6.0
Fatty acid alkanol amides 1.0-2.0
Alkyl-glucoside 10.0-20.0
Sodium chloride 1.0-3.0
1,2-benzisothiazole-3-ketone 0.1-0.3
Essence 0.2-0.4
Citric acid monohydrate 0.1-0.3
Deionized water 65-75.
A kind of preparation method of handwashing liquid of mild low-stimulation, preparation process is as follows:
By described raw materials in part by weight ratio, 70~85% of deionized water total amount wherein is heated in 60~80 ℃ and the placing material still, add aliphatic alcohol polyethenoxy (9) ether then while stirring, the lauryl amido propyl betaine, the cocamidopropyl propyl amide amine-oxides, fatty acid alkanol amides, alkyl-glucoside, after treating that described raw material all dissolves, solution is cooled to 35 ℃~45 ℃, add sodium chloride again, 1, the 2-benzisothiazole-3-ketone, essence and remaining deionized water, stirring and adjusting pH value with citric acid monohydrate is 6-8, leave standstill after stirring, obtain the handwashing liquid of described mild low-stimulation.
The present invention compared with prior art has following advantage:
1, the handwashing liquid of a kind of mild low-stimulation of the present invention selects that the amphoteric surfactant (lauryl amido propyl betaine, cocamidopropyl propyl amide amine-oxides) of non-ionic surface active agent (aliphatic alcohol polyethenoxy (9) ether), the mild low-stimulation of strong detergency, foam are abundant, fine and smooth non-ionic surface active agent (fatty acid alkanol amides) cooperates with native corn starch, the synthetic active matter alkyl-glucoside of glucose for use, synergism, gentle handguard in decontamination, cleaning.
2, handwashing liquid stability, the good water solubility of a kind of mild low-stimulation of the present invention, foam is abundant, easily flushing, moisturizing effect is remarkable.
3, the handwashing liquid of a kind of mild low-stimulation of the present invention is environmentally friendly, and is nontoxic, non-stimulated.
The specific embodiment
The invention will be further described below in conjunction with embodiment.
A kind of handwashing liquid of mild low-stimulation is prepared from by its ratio of weight and number by following raw material:
Aliphatic alcohol polyethenoxy (9) ether 1.0-5.0
Lauryl amido propyl betaine 3.0-5.0
Cocamidopropyl propyl amide amine-oxides 1.0-6.0
Fatty acid alkanol amides 1.0-2.0
Alkyl-glucoside 10.0-20.0
Sodium chloride 1.0-3.0
1,2-benzisothiazole-3-ketone 0.1-0.3
Essence 0.2-0.4
Citric acid monohydrate 0.1-0.3
Deionized water 65-75.
In the above-mentioned raw materials composition, aliphatic alcohol polyethenoxy (9) ether, fatty acid alkanol amides are non-ionic surface active agent, lauryl amido propyl betaine, cocamidopropyl propyl amide amine-oxides are amphoteric surfactant, and alkyl-glucoside is native corn starch, the synthetic active matter of glucose.
Above-described various raw material is technical grade.
Embodiment 1: a kind of handwashing liquid of mild low-stimulation is prepared from by its ratio of weight and number by following raw material:
Aliphatic alcohol polyethenoxy (9) ether 1.0
Lauryl amido propyl betaine 5.0
Cocamidopropyl propyl amide amine-oxides 2.0
Fatty acid alkanol amides 1.0
Alkyl-glucoside 20.0
Sodium chloride 1.0
1,2-benzisothiazole-3-ketone 0.1
Essence 0.3
Citric acid monohydrate 0.3
Deionized water 69.3.
The preparation method of the handwashing liquid of described mild low-stimulation is an example to produce this product of 100kg, and its preparation process is as follows:
The 50kg deionized water is heated in 60~80 ℃ and the placing material still, add aliphatic alcohol polyethenoxy (9) ether 1kg then while stirring, lauryl amido propyl betaine 5kg, cocamidopropyl propyl amide amine-oxides 2kg, fatty acid alkanol amides 1kg, alkyl-glucoside 20kg, after treating that described raw material all dissolves, solution is cooled to 35 ℃~45 ℃, add sodium chloride 1kg again, 1,2-benzisothiazole-3-ketone 0.1kg, essence 0.3kg and remaining deionized water 19.3kg, stirring and adjusting pH value with citric acid monohydrate 0.3kg is 6-8, leave standstill after stirring, obtain the handwashing liquid of described mild low-stimulation.
Embodiment 2: in the present embodiment, a kind of handwashing liquid of mild low-stimulation is prepared from by its ratio of weight and number by following raw material:
Aliphatic alcohol polyethenoxy (9) ether 2.5
Lauryl amido propyl betaine 4.5
Cocamidopropyl propyl amide amine-oxides 1.0
Fatty acid alkanol amides 2.0
Alkyl-glucoside 18.0
Sodium chloride 1.5
1,2-benzisothiazole-3-ketone 0.3
Essence 0.2
Citric acid monohydrate 0.3
Deionized water 69.7.
The preparation method of the handwashing liquid of the mild low-stimulation of present embodiment is with embodiment 1.
Embodiment 3: in the present embodiment, the handwashing liquid that is used for mild low-stimulation is prepared from by its ratio of weight and number by following raw material:
Aliphatic alcohol polyethenoxy (9) ether 5.0
Lauryl amido propyl betaine 3.5
Cocamidopropyl propyl amide amine-oxides 6.0
Fatty acid alkanol amides 1.5
Alkyl-glucoside 10.0
Sodium chloride 1.5
1,2-benzisothiazole-3-ketone 0.2
Essence 0.25
Citric acid monohydrate 0.1
Deionized water 71.95.
The preparation method of the handwashing liquid of the mild low-stimulation of present embodiment is with embodiment 1.
Embodiment 4: in the present embodiment, the handwashing liquid of mild low-stimulation is prepared from by its ratio of weight and number by following raw material:
Aliphatic alcohol polyethenoxy (9) ether 4.0
Lauryl amido propyl betaine 3.5
Cocamidopropyl propyl amide amine-oxides 5.0
Fatty acid alkanol amides 1.0
Alkyl-glucoside 14.0
Sodium chloride 3.0
1,2-benzisothiazole-3-ketone 0.15
Essence 0.4
Citric acid monohydrate 0.2
Deionized water 68.75.
The preparation method of the handwashing liquid of the mild low-stimulation of present embodiment is with embodiment 1.
Embodiment 5: in the present embodiment, the handwashing liquid of mild low-stimulation is prepared from by its ratio of weight and number by following raw material:
Aliphatic alcohol polyethenoxy (9) ether 5.0
Lauryl amido propyl betaine 3.0
Cocamidopropyl propyl amide amine-oxides 4.5
Fatty acid alkanol amides 1.5
Alkyl-glucoside 12.0
Sodium chloride 2.2
1,2-benzisothiazole-3-ketone 0.15
Essence 0.3
Citric acid monohydrate 0.2
Deionized water 71.15.
The preparation method of the handwashing liquid of the mild low-stimulation of present embodiment is with embodiment 1.
The handwashing liquid of mild low-stimulation of the present invention according to Ministry of Public Health " cosmetics health standard ", carries out toxicological experiment to submitted sample through Beijing Disease Prevention and Control Centre, and experimental result shows: rabbit repeatedly skin irritation test result is a nonirritant.

Claims (7)

1. the handwashing liquid of a mild low-stimulation is characterized in that: be prepared from by its ratio of weight and number by following raw material:
Aliphatic alcohol polyethenoxy (9) ether 1.0-5.0
Lauryl amido propyl betaine 3.0-5.0
Cocamidopropyl propyl amide amine-oxides 1.0-6.0
Fatty acid alkanol amides 1.0-2.0
Alkyl-glucoside 10.0-20.0
Sodium chloride 1.0-3.0
1,2-benzisothiazole-3-ketone 0.1-0.3
Essence 0.2-0.4
Citric acid monohydrate 0.1-0.3
Deionized water 65-75.
2. the handwashing liquid of mild low-stimulation according to claim 1 is characterized in that: be prepared from by its ratio of weight and number by following raw material:
Aliphatic alcohol polyethenoxy (9) ether 1.0
Lauryl amido propyl betaine 5.0
Cocamidopropyl propyl amide amine-oxides 2.0
Fatty acid alkanol amides 1.0
Alkyl-glucoside 20.0
Sodium chloride 1.0
1,2-benzisothiazole-3-ketone 0.1
Essence 0.3
Citric acid monohydrate 0.3
Deionized water 69.3.
3. the handwashing liquid of mild low-stimulation according to claim 1 is characterized in that: be prepared from by its ratio of weight and number by following raw material:
Aliphatic alcohol polyethenoxy (9) ether 2.5
Lauryl amido propyl betaine 4.5
Cocamidopropyl propyl amide amine-oxides 1.0
Fatty acid alkanol amides 2.0
Alkyl-glucoside 18.0
Sodium chloride 1.5
1,2-benzisothiazole-3-ketone 0.3
Essence 0.2
Citric acid monohydrate 0.3
Deionized water 69.7.
4. the handwashing liquid of mild low-stimulation according to claim 1 is characterized in that: be prepared from by its ratio of weight and number by following raw material:
Aliphatic alcohol polyethenoxy (9) ether 5.0
Lauryl amido propyl betaine 3.5
Cocamidopropyl propyl amide amine-oxides 6.0
Fatty acid alkanol amides 1.5
Alkyl-glucoside 10.0
Sodium chloride 1.5
1,2-benzisothiazole-3-ketone 0.2
Essence 0.25
Citric acid monohydrate 0.1
Deionized water 71.95.
5. the handwashing liquid of mild low-stimulation according to claim 1 is characterized in that: be prepared from by its ratio of weight and number by following raw material:
Aliphatic alcohol polyethenoxy (9) ether 4.0
Lauryl amido propyl betaine 3.5
Cocamidopropyl propyl amide amine-oxides 5.0
Fatty acid alkanol amides 1.0
Alkyl-glucoside 14.0
Sodium chloride 3.0
1,2-benzisothiazole-3-ketone 0.15
Essence 0.4
Citric acid monohydrate 0.2
Deionized water 68.75.
6. the handwashing liquid of mild low-stimulation according to claim 1 is characterized in that: be prepared from by its ratio of weight and number by following raw material:
Aliphatic alcohol polyethenoxy (9) ether 5.0
Lauryl amido propyl betaine 3.0
Cocamidopropyl propyl amide amine-oxides 4.5
Fatty acid alkanol amides 1.5
Alkyl-glucoside 12.0
Sodium chloride 2.2
1,2-benzisothiazole-3-ketone 0.15
Essence 0.3
Citric acid monohydrate 0.2
Deionized water 71.15.
7. the preparation method of the handwashing liquid of a mild low-stimulation as claimed in claim 1, it is characterized in that preparation process is as follows: by described raw materials in part by weight ratio, 70~85% of deionized water total amount wherein is heated in 60~80 ℃ and the placing material still, add aliphatic alcohol polyethenoxy (9) ether then while stirring, the lauryl amido propyl betaine, the cocamidopropyl propyl amide amine-oxides, fatty acid alkanol amides, alkyl-glucoside, after treating that described raw material all dissolves, solution is cooled to 35 ℃~45 ℃, add sodium chloride again, 1, the 2-benzisothiazole-3-ketone, essence and remaining deionized water, stirring and adjusting pH value with citric acid monohydrate is 6-8, leave standstill after stirring, obtain the handwashing liquid of described mild low-stimulation.
CN2010101731059A 2010-05-17 2010-05-17 Mild low-stimulation hand sanitizer and preparation method thereof Active CN101816625B (en)

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102451098A (en) * 2010-10-28 2012-05-16 四川久大制盐有限责任公司 Mineral salt hand sanitizer and preparation method thereof
CN102631295A (en) * 2012-03-30 2012-08-15 中国日用化学工业研究院 Multifunctional foam liquid soap containing glucoside and derivatives of glucoside, and preparation method thereof
CN103893042A (en) * 2012-12-28 2014-07-02 青岛锦涟鑫商贸有限公司 Method for producing hand sanitizer

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108379148A (en) * 2018-04-07 2018-08-10 广州市索柔生物科技有限公司 Low stimulation cleaning compositions of one kind and preparation method thereof

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1234414A (en) * 1998-05-05 1999-11-10 罗姆和哈斯公司 Polymer release-control composition
CN2461296Y (en) * 2001-01-10 2001-11-28 陈书侗 Sterilizing articles
CN1580220A (en) * 2003-08-11 2005-02-16 上海白猫有限公司 Disinfecting mite-removing cleaning agent for air conditioner

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1234414A (en) * 1998-05-05 1999-11-10 罗姆和哈斯公司 Polymer release-control composition
CN2461296Y (en) * 2001-01-10 2001-11-28 陈书侗 Sterilizing articles
CN1580220A (en) * 2003-08-11 2005-02-16 上海白猫有限公司 Disinfecting mite-removing cleaning agent for air conditioner

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102451098A (en) * 2010-10-28 2012-05-16 四川久大制盐有限责任公司 Mineral salt hand sanitizer and preparation method thereof
CN102451098B (en) * 2010-10-28 2013-04-24 四川久大制盐有限责任公司 Mineral salt hand sanitizer and preparation method thereof
CN102631295A (en) * 2012-03-30 2012-08-15 中国日用化学工业研究院 Multifunctional foam liquid soap containing glucoside and derivatives of glucoside, and preparation method thereof
CN102631295B (en) * 2012-03-30 2013-07-03 中国日用化学工业研究院 Multifunctional foam liquid soap containing glucoside and derivatives of glucoside, and preparation method thereof
CN103893042A (en) * 2012-12-28 2014-07-02 青岛锦涟鑫商贸有限公司 Method for producing hand sanitizer

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PE01 Entry into force of the registration of the contract for pledge of patent right

Denomination of invention: Mild low-stimulation hand sanitizer and preparation method thereof

Effective date of registration: 20120502

Granted publication date: 20110720

Pledgee: Standard Chartered Bank (China) Co., Ltd. Beijing branch

Pledgor: Beijing Lusan Chemical Co., Ltd.

Registration number: 2012990000183

PC01 Cancellation of the registration of the contract for pledge of patent right

Date of cancellation: 20141209

Granted publication date: 20110720

Pledgee: Standard Chartered Bank (China) Co., Ltd. Beijing branch

Pledgor: Beijing Lusan Chemical Co., Ltd.

Registration number: 2012990000183

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CP03 Change of name, title or address

Address after: 100094 block B, building 1, yard 2, Yongcheng North Road, Yongfeng Industrial base, Haidian District, Beijing

Patentee after: Beijing green umbrella Technology Co.,Ltd.

Address before: 100094, No. 3, North Road, Yongfeng industrial base, Beijing, Haidian District

Patentee before: Beijing Lvsan Chemistry Co.,Ltd.

CP03 Change of name, title or address