CN101803735B - Lactation promoting composition and preparation method thereof - Google Patents

Lactation promoting composition and preparation method thereof Download PDF

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CN101803735B
CN101803735B CN2010101530416A CN201010153041A CN101803735B CN 101803735 B CN101803735 B CN 101803735B CN 2010101530416 A CN2010101530416 A CN 2010101530416A CN 201010153041 A CN201010153041 A CN 201010153041A CN 101803735 B CN101803735 B CN 101803735B
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lactation
fry
promoting composition
stir
preparation
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CN101803735A (en
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郭成芳
王骥
陈杰
王健
王肖
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LONGXI ZHONGTIAN PHARMACEUTICAL CO Ltd
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Abstract

The invention provides a lactation promoting composition, made by adopting the following raw materials by parts by weight: 92-99 parts of hulless oat and 0.3-1 part of roasted malt. The invention also provides a preparation method of the lactation promoting composition and application thereof in promoting lactation of puerpera. The lactation promoting composition of the invention adopts homologous plant food medicine raw materials, hulless oat and roasted malt are taken as main ingredients, the two generate synergistic effect, curative effect is achieved while nourishing, conditioning and improving endocrine level, hypogalactia and lack lactation symptoms of puerpera can be obviously improved, no toxic or side effect can be produced, and the lactation promoting composition can partially substitute drug therapy; and the preparation method of the composition of the invention is simple.

Description

A kind of lactation promoting composition and preparation method thereof
Technical field
The present invention relates to a kind of health products that promote galactogogue action that have, specifically, relating to a kind of is the lactation promoting composition of primary raw material with naked oats and coloured malt.
Background technology
Since melamine " malicious milk powder " incident in 2008 broke out in China, China's dairy products industry had been suffered enormous economic loss and trust crisis, and people have proposed query to the security of dairy products again.
Before for many years, breast milk just has been proved to be neonatal first-selected healthy food, and is more healthy and clever than the baby of nursings such as milk with breast-fed babies.According to State Family Planning Commission's statistics, the neonate's breastfeeding rate in 4 months reaches 92.88%, that is to say that every year, the rarest 1,800 ten thousand puerperas carried out breast-feeding to the baby.Add up according to data center of State Family Planning Commission: 39.8% puerpera has serious agalasisa, the few symptom of breast; 46.3% puerpera lactiferous ducts occurs and stops up concurrent acute mastitis in the nursing process; Will stand swollen breasts in various degree during 62.8% puerpera's delaactation, the quantity that above crowd adds up has surpassed 1,800 ten thousand people.
Women breast-feeding their children's agalasisa, few newborn symptom are comparatively common in China town and country, and this not only constitutes a threat to the healthy of mother and baby, also the household economy holding capacity has been proposed challenge.The few common two kinds of situation that have of breast in puerpera postpartum: the one, mammary gland is obstructed, and theory of traditional Chinese medical science is thought true card; The 2nd, milk is few, belongs to asthenic symptoms.Asthenic symptoms show as and have a delicate constitution, lusterless complexion, palpitation, unconsciously sweat and tire, and how because of weakness of the spleen and the stomach, insufficiency of vital energy and blood, or due to the stagnation of liver qi, the women of most of agalasisas, few breast is asthenic symptoms.
The galactopoiesis level depends mainly on the prolactin (PRL) in puerpera's body, and prolactin is mainly synthetic by the hypophysis secretion, also can be synthetic by the outer tissue secretion of hypophysis, and the hypothalamus dopamine then can suppress hypophysis secretion PRL, thereby reaches the effect of regulating lactation.Normal puerpera prolactin secretion level physiological in lactation raises, thereby promotes galactosis.
PRL can not only promote mammogenesis and lactation; Still connect the central nervous system immune important medium of unifying; Has the promotion immune cell propagation; Increase the effect that IgG antibody forms, an amount of expression of PRL is significant to regulating lymphocyte immunologic function, so breast-feeding is the effective way of puerpera's self-recovery and baby's acquired immunity antibody.And the puerpera is just contained rich in amino acid in the Ruzhong, like glutamic acid, taurine etc., organizes function and intelligence development, bile metabolism to have important function to promoting newborn baby.
But PRL also has close getting in touch with the generation of many immune correlated diseases, development, and therefore many immunity diseases mostly occur at women's term.For example,, then bring out hyperprolactinemia easily, cause menstrual disorder, amenorrhoea, excessive breast, osteoporosis etc., even cause that the sick incidence of disease of reproductive system knurl increases if PRL content surpasses normal level.At present, high lactagogue mass formed by blood stasis mainly is that this is because the lactagogue medicine contains the prolactin composition mostly on the market because drug-induced; And when illness appearred in the prolactin too high levels, the inhibition regulating action of dopamine was but also not obvious, and relevant research is also further being goed deep into.
In order to address the above problem; Reduce the dependence of patient to medicine, reduce the bad reaction of Lactogenic medicine, the health-care efficacy of performance natural green food is a best mode; The inventor allocates through scientific nutrition; Developing with naked oats and coloured malt is the green organic food of the short galactosis of main component, can effectively improve hypogalactia of lying-in woman, few newborn symptom, and have no side effect.
Summary of the invention
The object of the present invention is to provide a kind of hypogalactia of lying-in woman, newborn symptom, and the lactation promoting composition that has no side effect less improved.
Another object of the present invention is to provide said preparation of compositions method.
In order to realize the object of the invention, lactation promoting composition of the present invention, it adopts the raw material of following weight portion to process: 92~99 parts of naked oats, 0.3~1 part of coloured malt.
Wherein, preferably 93.9 parts of naked oats, 0.5 part of coloured malt.
Lactation promoting composition of the present invention, its raw material can also comprise: pea 3~8 weight portions, rde bean 1~2 weight portion, preferably, 4.7 parts of peas, 1 part of rde bean.
The preparation method of lactation promoting composition of the present invention comprises the steps:
1) bake stir-fry respectively after will the raw material for washing except that coloured malt drying, 120~160 ℃ of temperature are fried in roasting, and roasting stir-fry time 8~15min fries to savory getting final product, and attention can not stir-bake to brown;
2) raw material after the above-mentioned roasting stir-fry is mixed with coloured malt, pulverize,, can make the lactation promoting composition product through 50~100 mesh sieve branches.
Wherein, roasting is fried temperature and is preferably 140 ℃, and the roasting stir-fry time is preferably 10min.
Lactation promoting composition bath of the present invention is taken in the application of lactation promoting composition of the present invention aspect the promotion cesarean lactation, and can be according to puerpera's individual difference and breast-feeding time adjustment dose and Time of Administration, and instructions of taking is simple.
Coloured malt of the present invention can obtain through commercially available; Also can Fructus Hordei Germinatus roasting stir-fry be obtained, roasting is fried temperature and is about 140 ℃, and the roasting stir-fry time is about 10min, fries extremely savory getting final product, and attention can not stir-bake to brown.The application of coloured malt in ancient prescription lactagogue secret recipe has long history; The little relieving dyspepsia that promptly plays of consumption, liver soothing and depression relief and the effect of lactagogue, consumption greatly then plays dissipation strength; Dissipation qi and blood and the effect of delaactation, all on the books in works such as " the southern regions of the Yunnan Province book on Chinese herbal medicine ", " Records of Tradition Chinese and Western Medicine in Combination ".
Naked oats of the present invention are selected the high-quality naked oats of the above growth of height above sea level 2000m, and it contains trace elements such as rich in protein, vitamin and phosphorus, iron, have the mammogenesis of promotion, increase effects such as galactosis, reducing blood lipid.With coloured malt and naked oats the two with specific proportioning compatibility, can produce synergy, promote cesarean lactation, obviously improve hypogalactia of lying-in woman, few newborn symptom, and have no side effect.
In addition, pea and rde bean are rich in protein, vitamin, amino acid, dietary fiber, trace element etc., have balanced nutrients, the effect of makeup energy.Pea, rde bean are joined in above-mentioned naked oats, the coloured malt composition by a certain percentage; Decapacitation obviously improves outside hypogalactia of lying-in woman, the few newborn symptom, and also gravid woman, climacteric women being improved diseases such as insomnia, osteoporosis, the prevention proliferation of mammary gland, breast cancer, hypophysoma has the good health care effect.
The invention has the advantages that lactation promoting composition of the present invention is a main component with naked oats and coloured malt, the two compatibility produces synergy; Can also add other nutritious raw materials, like pea, rde bean etc., this prescription is selected the raw material of integration of drinking and medicinal herbs for use; In nourishing conditioning, improve the effect that reaches treatment on the basis of endocrine level, can obviously improve hypogalactia of lying-in woman, few newborn symptom; And having no side effect, but part alternative medicine treatment; And present composition preparation method is simple, and puerpera's bath is taken and got final product, and is easy to use.
The specific embodiment
Below further specify the present invention through embodiment, but be not used for limiting scope of the present invention.
Embodiment 1
Prescription: naked oats 99g, coloured malt 1g.
The preparation method: 1) naked oats are cleaned dried the back and fry till savory in roasting under 120 ℃ of temperature, the roasting stir-fry time is about 15min;
2) naked oats after the above-mentioned roasting stir-fry are mixed with coloured malt, pulverize, 50 mesh sieve branches obtain the lactation promoting composition product.
Embodiment 2
Prescription: naked oats 92g, pea 3g, rde bean 1g, coloured malt 0.3g.
The preparation method: 1) naked oats, pea, rde bean are cleaned baked stir-fry respectively after drying, it is 160 ℃ that temperature is fried in roasting, fries to savory get final product, bakes the stir-fry time to be about 8~10min;
2) raw material after the above-mentioned roasting stir-fry is mixed, pulverizes with coloured malt, after 80 mesh sieves divide, make the lactation promoting composition product.
Embodiment 3
Prescription: naked oats 93.9g, pea 4.7g, rde bean 1g, coloured malt 0.5g.
The preparation method: 1) naked oats, pea, rde bean are cleaned to bake respectively after drying fry roasting to fry temperature be 140 ℃, fry to savory get final product, attention can not stir-bake to brown, bakes the stir-fry time to be about 10~12min;
2) raw material after the above-mentioned roasting stir-fry is mixed with coloured malt, pulverize, after 80 mesh sieves divide, make the lactation promoting composition product.
Below further specify the present invention through the lactagogue effect test.
Test Example 1
SD rat male and female half and half are raised with cage, find that newborn mouse childbirth postscript is 1d; 8 of every nest newborn mouses, female mouse are divided into 5 groups at random, 8 every group; Except that normal group, all the other 4 groups female mouse lumbar injection every day levodopa parenteral solution (Spring in Pig House of Shanghai Fengxian pharmaceutical factory, product batch number 001015) 10mg.kg -1, inject 10d continuously.Respectively female mouse is carried out intraperitoneal administration by dosage shown in the table 1 simultaneously; Successive administration 9d; Wherein, The positive group of granule for expelling obstruction of galactophore gives granule for expelling obstruction of galactophore (Shanghai Chinese medicine two factories, product batch number 000407), and composition low dose group and composition high dose group give the lactation promoting composition product that embodiment 3 makes respectively.The newborn mouse 2d that is born promptly divides cage with female mouse, and weighing newborn mouse weight respectively behind the 9h is raised female mouse and newborn mouse then with cage; The weight of weighing newborn mouse behind the 1h, the difference of front and back weighing are the lactation amount in female mouse 10h, and measure 1 time in the identical time period every day; In the process of the test; Ad lib, METHOD FOR CONTINUOUS DETERMINATION 9d, the result is as shown in table 1.
The how excellent prescription of table 1 breast brings out the influence
Figure GSA00000075442000051
of lactation amount of female mouse day of hypogalactia to levodopa
Figure GSA00000075442000052
Annotate: *Compare P<0.01 with normal control; ▲ ▲Compare P<0.01 with the levodopa model group
Can find out from table 1, compare that the female mouse lactation amount of levodopa model group begins obviously to reduce behind 6d after the administration with normal group; Compare with model group, the lactation amount of positive controls and composition high dose group 5d stepmother mouse after administration has tangible increase, and the lactation amount comparing difference of the female mouse of composition low dose group and high dose group is not remarkable.
Test Example 2
53 hypogalactias, few newborn puerperas' lactation have attempted the lactation promoting composition of the embodiment of the invention 3 voluntarily.Above-mentioned 53 puerperas are divided into three types by its hypogalactia, few newborn symptom, and wherein, hypogalactia type A is the agalasisa symptom, totally 17 people; Hypogalactia type B, C are the less symptom of galactosis amount, wherein, heavier totally 20 people of category-B hypogalactia symptom, C class hypogalactia symptom is more totally 16 people.Every puerpera takes the lactation promoting composition of 100g embodiment 3 every day, takes and plays the beginning onset on the 3rd day, takes the short lactation effect of statistics after 1 month continuously, and the result is as shown in table 2.
Effect standard: produce effects: baby's total eclipse breast milk need not to feed other dairy products; Effectively: baby's solar eclipse dairy products amount obviously reduces, and the cesarean lactation amount increases; Invalid: no significant change before and after the cesarean lactation amount is taken, the baby relies on dairy products every day and feeds.
The test effect of table 2 lactation promoting composition
Figure GSA00000075442000061
The result shows that this lactagogue food all has tangible lactagogue effect to hypogalactia type A, B, C.
Though, the present invention has been done detailed description in the preceding text through general explanation, embodiment and the test of pesticide effectiveness, should not be construed as limitation of the present invention.Those of ordinary skills will be understood that; Under the situation that does not deviate from the present invention's spirit and essence; Replace pea of the present invention, rde bean etc. with other nutraceutical, or, all fall among the scope of the present invention modification or replacement that preparation method of the present invention did.

Claims (3)

1. a lactation promoting composition is characterized in that, it adopts the raw material of following weight portion to process: naked oats 93.9g, pea 4.7g, rde bean 1g, coloured malt 0.5g,
The preparation method:
1) naked oats, pea, rde bean are cleaned to bake respectively after drying fry roasting to fry temperature be 140 ℃, fry to savory get final product, attention can not stir-bake to brown, and baking the stir-fry time is 10 ~ 12min;
2) raw material after the above-mentioned roasting stir-fry is mixed with coloured malt, pulverize, after 80 mesh sieves divide, make the lactation promoting composition product.
2. a method for preparing the described lactation promoting composition of claim 1 is characterized in that, this method may further comprise the steps:
1) naked oats, pea, rde bean are cleaned baked stir-fry respectively after drying, it is 140 ℃ that temperature is fried in roasting, fries to savory get final product, and attention can not stir-bake to brown, and baking the stir-fry time is 10 ~ 12min;
2) raw material after the above-mentioned roasting stir-fry is mixed with coloured malt, pulverize, after 80 mesh sieves divide, make the lactation promoting composition product.
3. the described composition of claim 1 promotes the Application in Food of cesarean lactation in preparation.
CN2010101530416A 2010-04-20 2010-04-20 Lactation promoting composition and preparation method thereof Expired - Fee Related CN101803735B (en)

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CN105412555A (en) * 2016-01-20 2016-03-23 青岛云天生物技术有限公司 Medicine composition for promoting postpartum lactating and preparation method thereof

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1385112A (en) * 2001-05-11 2002-12-18 沈美芬 Natural beverage and production method thereof
CN1931332A (en) * 2006-09-16 2007-03-21 许爱华 Decoction for stopping milk secretion
CN101253938A (en) * 2007-03-01 2008-09-03 乔继华 Milk cattle beneficiated burden material complemental feed
CN101259221A (en) * 2008-04-10 2008-09-10 孔祥雷 Milk withdrawal powder

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1385112A (en) * 2001-05-11 2002-12-18 沈美芬 Natural beverage and production method thereof
CN1931332A (en) * 2006-09-16 2007-03-21 许爱华 Decoction for stopping milk secretion
CN101253938A (en) * 2007-03-01 2008-09-03 乔继华 Milk cattle beneficiated burden material complemental feed
CN101259221A (en) * 2008-04-10 2008-09-10 孔祥雷 Milk withdrawal powder

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