CN101772697B - 用于聚集颗粒的系统和方法 - Google Patents

用于聚集颗粒的系统和方法 Download PDF

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Publication number
CN101772697B
CN101772697B CN2008801016866A CN200880101686A CN101772697B CN 101772697 B CN101772697 B CN 101772697B CN 2008801016866 A CN2008801016866 A CN 2008801016866A CN 200880101686 A CN200880101686 A CN 200880101686A CN 101772697 B CN101772697 B CN 101772697B
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particles
particle
suspension
channel
selectively
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CN101772697A (zh
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亚历山大·莱申斯基
阿维谢伊·布兰斯基
科琳·纳塔尼尔
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Technion Research and Development Foundation Ltd
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Technion Research and Development Foundation Ltd
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/5306—Improving reaction conditions, e.g. reduction of non-specific binding, promotion of specific binding
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1404—Handling flow, e.g. hydrodynamic focusing
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502769—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by multiphase flow arrangements
    • B01L3/502776—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by multiphase flow arrangements specially adapted for focusing or laminating flows
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1404—Handling flow, e.g. hydrodynamic focusing
    • G01N15/1409—Handling samples, e.g. injecting samples
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2203/00—Investigating strength properties of solid materials by application of mechanical stress
    • G01N2203/0058—Kind of property studied
    • G01N2203/0092—Visco-elasticity, solidification, curing, cross-linking degree, vulcanisation or strength properties of semi-solid materials
    • G01N2203/0094—Visco-elasticity

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Dispersion Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Clinical Laboratory Science (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
CN2008801016866A 2007-06-07 2008-06-05 用于聚集颗粒的系统和方法 Active CN101772697B (zh)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201310360814.1A CN103543093B (zh) 2007-06-07 2008-06-05 细胞测量设备

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US92499807P 2007-06-07 2007-06-07
US60/924,998 2007-06-07
PCT/IL2008/000772 WO2008149365A2 (en) 2007-06-07 2008-06-05 Systems and methods for focusing particles

Related Child Applications (1)

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CN201310360814.1A Division CN103543093B (zh) 2007-06-07 2008-06-05 细胞测量设备

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CN101772697A CN101772697A (zh) 2010-07-07
CN101772697B true CN101772697B (zh) 2013-08-21

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CN2008801016866A Active CN101772697B (zh) 2007-06-07 2008-06-05 用于聚集颗粒的系统和方法
CN201310360814.1A Active CN103543093B (zh) 2007-06-07 2008-06-05 细胞测量设备

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US (2) US8642288B2 (https=)
EP (1) EP2153199B1 (https=)
JP (2) JP5337151B2 (https=)
CN (2) CN101772697B (https=)
WO (1) WO2008149365A2 (https=)

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EP2813837B1 (en) 2008-10-02 2020-05-27 Pixcell Medical Technologies Ltd. Optical imaging based on viscoelastic focusing
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GB201113309D0 (en) 2011-08-02 2011-09-14 Izon Science Ltd Characterisation of particles
US20150362421A1 (en) * 2012-06-22 2015-12-17 Malvern Instruments Limited Particle characterization
US10509976B2 (en) 2012-06-22 2019-12-17 Malvern Panalytical Limited Heterogeneous fluid sample characterization
CA2876358A1 (en) * 2012-06-22 2013-12-27 Malvern Instruments Limited Particle characterization
JP6311312B2 (ja) * 2012-07-25 2018-04-18 ソニー株式会社 微小粒子測定装置及び微小粒子測定装置における送液方法
US9372144B2 (en) * 2013-10-01 2016-06-21 Owl biomedical, Inc. Particle manipulation system with out-of-plane channel
US9279750B2 (en) 2013-03-15 2016-03-08 Iris International, Inc. Method and composition for staining and sample processing
JP6523245B2 (ja) 2013-03-15 2019-05-29 アイリス インターナショナル， インコーポレイテッド 血液試料における粒子分析のためのシース液システム及び方法
WO2015033090A1 (en) * 2013-09-03 2015-03-12 Izon Science Limited Measurement of particle charge
US10307760B2 (en) 2014-01-30 2019-06-04 The General Hospital Corporation Inertio-elastic focusing of particles in microchannels
EP2907574A1 (en) 2014-02-13 2015-08-19 OWL Biobedical, Inc. Microfluidic system with viscoelastic fluid
EP3245002A4 (en) 2015-01-14 2018-08-01 Pixcell Medical Technologies Ltd. Disposable cartridge for sample fluid analysis
RU2655225C1 (ru) * 2015-04-17 2018-05-24 Конинклейке Филипс Н.В. Обработка пыли
KR101855490B1 (ko) * 2016-01-22 2018-05-08 한국과학기술원 점탄성유체와 점성유체의 병행층류를 이용한 미소 입자 분리 및 세정 방법
JP6134402B1 (ja) * 2016-01-29 2017-05-24 シスメックス株式会社 生体試料撮像装置及び生体試料撮像方法
CN106248528A (zh) * 2016-09-27 2016-12-21 中国石油天然气股份有限公司 一种聚合物弹性强弱的评价方法
US11474023B2 (en) 2017-06-02 2022-10-18 The General Hospital Corporation Oscillatory focusing of particles in channels
CN108627448A (zh) * 2018-06-05 2018-10-09 江苏卓微生物科技有限公司 微粒计数的方法
US11185861B2 (en) 2018-06-13 2021-11-30 International Business Machines Corporation Multistage deterministic lateral displacement device for particle separation
US20240060031A1 (en) * 2020-09-29 2024-02-22 1087 Systems, Inc Graded Bioprocess Monitoring
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JP7152622B1 (ja) * 2022-03-30 2022-10-12 ポーラ化成工業株式会社 ウルトラファインバブルの気泡濃度測定方法

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Publication number Publication date
JP2010529452A (ja) 2010-08-26
WO2008149365A3 (en) 2009-03-05
US20140113358A1 (en) 2014-04-24
CN103543093A (zh) 2014-01-29
US9470679B2 (en) 2016-10-18
JP2013217946A (ja) 2013-10-24
JP5337151B2 (ja) 2013-11-06
CN101772697A (zh) 2010-07-07
US20100178666A1 (en) 2010-07-15
EP2153199A2 (en) 2010-02-17
CN103543093B (zh) 2016-08-10
US8642288B2 (en) 2014-02-04
JP5901582B2 (ja) 2016-04-13
WO2008149365A2 (en) 2008-12-11
EP2153199B1 (en) 2016-10-19

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