CN101747390A - 一种依达拉奉代谢产物的合成工艺 - Google Patents
一种依达拉奉代谢产物的合成工艺 Download PDFInfo
- Publication number
- CN101747390A CN101747390A CN200910264437A CN200910264437A CN101747390A CN 101747390 A CN101747390 A CN 101747390A CN 200910264437 A CN200910264437 A CN 200910264437A CN 200910264437 A CN200910264437 A CN 200910264437A CN 101747390 A CN101747390 A CN 101747390A
- Authority
- CN
- China
- Prior art keywords
- preparation technology
- reaction
- water
- edaravone
- organic solvent
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Description
Claims (10)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN 200910264437 CN101747390B (zh) | 2009-12-22 | 2009-12-22 | 一种依达拉奉代谢产物的合成工艺 |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN 200910264437 CN101747390B (zh) | 2009-12-22 | 2009-12-22 | 一种依达拉奉代谢产物的合成工艺 |
Publications (2)
Publication Number | Publication Date |
---|---|
CN101747390A true CN101747390A (zh) | 2010-06-23 |
CN101747390B CN101747390B (zh) | 2012-05-23 |
Family
ID=42475062
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN 200910264437 Active CN101747390B (zh) | 2009-12-22 | 2009-12-22 | 一种依达拉奉代谢产物的合成工艺 |
Country Status (1)
Country | Link |
---|---|
CN (1) | CN101747390B (zh) |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102127020A (zh) * | 2010-12-02 | 2011-07-20 | 海南美兰史克制药有限公司 | 一种依达拉奉化合物及其新制法 |
CN106146573A (zh) * | 2015-04-16 | 2016-11-23 | 复旦大学 | 益母草碱代谢物及其制备方法 |
WO2020038279A1 (zh) * | 2018-08-22 | 2020-02-27 | 天津谷堆生物医药科技有限公司 | 取代吡唑类化合物、其制备方法、药物组合物及用途 |
-
2009
- 2009-12-22 CN CN 200910264437 patent/CN101747390B/zh active Active
Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102127020A (zh) * | 2010-12-02 | 2011-07-20 | 海南美兰史克制药有限公司 | 一种依达拉奉化合物及其新制法 |
CN106146573A (zh) * | 2015-04-16 | 2016-11-23 | 复旦大学 | 益母草碱代谢物及其制备方法 |
WO2020038279A1 (zh) * | 2018-08-22 | 2020-02-27 | 天津谷堆生物医药科技有限公司 | 取代吡唑类化合物、其制备方法、药物组合物及用途 |
CN110857285A (zh) * | 2018-08-22 | 2020-03-03 | 天津谷堆生物医药科技有限公司 | 取代吡唑类化合物、其制备方法、药物组合物及用途 |
CN110857285B (zh) * | 2018-08-22 | 2022-12-20 | 江苏万高药业股份有限公司 | 取代吡唑类化合物、其制备方法、药物组合物及用途 |
Also Published As
Publication number | Publication date |
---|---|
CN101747390B (zh) | 2012-05-23 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CN104086379B (zh) | 达格列净中间体的合成方法 | |
CN101657462B (zh) | 卡培他滨的制备方法及其中间体 | |
CN101538228B (zh) | 抗流感和禽流感病毒药物化合物帕拉米韦的合成方法 | |
CN101747390B (zh) | 一种依达拉奉代谢产物的合成工艺 | |
CN109180662A (zh) | 一种卡格列净的制备方法 | |
ITMI20101239A1 (it) | Processo ed intermedi per la preparazione di un principio attivo | |
CN102702232A (zh) | 一种精制头孢孟多酯钠的方法 | |
CN112661736A (zh) | 一种泰格列净中间体的合成方法 | |
CN103130708B (zh) | 一种n-叔丁氧羰基-4-硝基哌啶的制备方法 | |
CN101759740A (zh) | 一种合成3-α-乙酰氧基-去氧雄甾-5-烯-17-酮的方法 | |
EP2241543A1 (en) | Process for the preparation of 2,4,6-octatriene-1-oic acid and 2,4,6-octatriene-1-ol | |
CN111116493B (zh) | 一种制备Apabetalone的方法、中间体及其中间体的制备方法 | |
CN111018928B (zh) | 一种天麻素半水合物的合成方法及其应用 | |
CN101239998A (zh) | 一种1,2,3-三乙酰基-5-脱氧-d-核糖合成方法 | |
CN101792477A (zh) | 具抗癌活性的乙酰熊果酰三乙醇胺单酯及其制备方法 | |
JP7344983B2 (ja) | ケノデオキシコール酸誘導体の調製方法 | |
CN105541815B (zh) | 一种卡格列净的制备方法 | |
CN115894303B (zh) | 一种(3-氨基双环[1.1.1]戊烷-1-基)氨基甲酸叔丁酯及其中间体的制备方法 | |
RU2483055C1 (ru) | Способ получения 1,5-бис(2-гидроксифенокси)-3-оксапентана моногидрата | |
CN101805380A (zh) | 一种制备(3s,5s)-2,3-二羟基-5-羟甲基四氢呋喃三乙酸酯的方法 | |
CN112939830B (zh) | 一种烯基硫醚对邻亚甲基苯醌的亲核反应方法 | |
CN101570493B (zh) | 一种(3s,4s)-4-氨基-3-羟基-6-甲基庚酸及其类似物的制备方法 | |
CN115819307A (zh) | 一种前列腺素e1的制备方法 | |
CN108047116B (zh) | R-5-(2-氨基丙基)-1-(3-羟基丙基)-7-腈基吲哚啉的制备方法 | |
CN117069782A (zh) | 一种具有α-立体选择性的糖苷类化合物通用关键中间体的制备方法 |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
C06 | Publication | ||
PB01 | Publication | ||
C10 | Entry into substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
C14 | Grant of patent or utility model | ||
GR01 | Patent grant | ||
C41 | Transfer of patent application or patent right or utility model | ||
TR01 | Transfer of patent right |
Effective date of registration: 20160720 Address after: 210042 Xuanwu District, Xuanwu District, Jiangsu, Nanjing No. 699 -18 Patentee after: Jiangsu Simcere Pharmaceutical Co., Ltd. Patentee after: Nanjing Simcere Dongyuan Pharmaceutical Co., Ltd. Address before: 210042 Xuanwu District, Xuanwu District, Jiangsu, Nanjing No. 699 -18 Patentee before: Jiangsu Simcere Pharmaceutical Research Company Limited Patentee before: Nanjing Simcere Dongyuan Pharmaceutical Co., Ltd. |
|
CP01 | Change in the name or title of a patent holder | ||
CP01 | Change in the name or title of a patent holder |
Address after: 210042 -18, Xuanwu Avenue, Xuanwu District, Jiangsu, Nanjing, 699 Patentee after: JIANGSU SIMCERE PHARMACEUTICAL Co.,Ltd. Patentee after: SIMCERE PHARMACEUTICAL Group Address before: 210042 -18, Xuanwu Avenue, Xuanwu District, Jiangsu, Nanjing, 699 Patentee before: JIANGSU SIMCERE PHARMACEUTICAL Co.,Ltd. Patentee before: NANJING SIMCERE DONGYUAN PHARMACEUTICA Co.,Ltd. |