CN101721682B - 重组人成纤维细胞生长因子7突变体在制备治疗宫颈糜烂的药物中的应用 - Google Patents
重组人成纤维细胞生长因子7突变体在制备治疗宫颈糜烂的药物中的应用 Download PDFInfo
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- CN101721682B CN101721682B CN 200910216184 CN200910216184A CN101721682B CN 101721682 B CN101721682 B CN 101721682B CN 200910216184 CN200910216184 CN 200910216184 CN 200910216184 A CN200910216184 A CN 200910216184A CN 101721682 B CN101721682 B CN 101721682B
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Abstract
Description
组别 | 剂量(μg/ml) |
正常对照组 | 注射用水 |
模型对照组 | 注射用水 |
溶媒对照组 | 溶解液 |
低剂量组 | 2.5 |
中剂量组 | 10 |
高剂量组 | 20 |
项目 | 组织学描述 | 评分 |
黏膜病变 | 未见明显变性坏死、脱落及溃疡 | 0 |
可见轻度变性坏死、脱落及溃疡 | 1 | |
可见明显变性坏死、脱落及溃疡 | 2 | |
可见大量变性坏死、脱落及溃疡 | 3 | |
黏膜下层血管扩张充血 | 未见明显扩张血管 | 0 |
可见轻度扩张血管 | 1 | |
未见明显扩张血管 | 2 | |
未见较多扩张血管 | 3 | |
黏膜下层炎细胞浸润 | 未见明显炎细胞浸润 | 0 |
可见轻度炎细胞浸润 | 1 | |
可见明显炎细胞浸润 | 2 | |
可见大量炎细胞浸润 | 3 | |
脓肿 | 无 | 0 |
有 | 1 |
组别 | 剂量(μg/ml) | 阴道-宫颈指数(%) |
空白组 | - | 0.161±0.019 |
模型组 | - | 0.324±0.163 |
对照组 | 0.304±0.202 | |
低剂量组 | 2.5 | 0.178±0.162 |
中剂量组 | 10 | 0.146±0.135 |
高剂量组 | 20 | 0.101±0.105 |
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CN 200910216184 CN101721682B (zh) | 2009-11-10 | 2009-11-10 | 重组人成纤维细胞生长因子7突变体在制备治疗宫颈糜烂的药物中的应用 |
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CN 200910216184 CN101721682B (zh) | 2009-11-10 | 2009-11-10 | 重组人成纤维细胞生长因子7突变体在制备治疗宫颈糜烂的药物中的应用 |
Publications (2)
Publication Number | Publication Date |
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CN101721682A CN101721682A (zh) | 2010-06-09 |
CN101721682B true CN101721682B (zh) | 2013-01-23 |
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CN 200910216184 Active CN101721682B (zh) | 2009-11-10 | 2009-11-10 | 重组人成纤维细胞生长因子7突变体在制备治疗宫颈糜烂的药物中的应用 |
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CN (1) | CN101721682B (zh) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
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CN107158363A (zh) * | 2017-05-16 | 2017-09-15 | 张莎莎 | 一种用于治疗宫颈糜烂的修复液 |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1169733A (zh) * | 1994-10-13 | 1998-01-07 | 安姆根有限公司 | 角化细胞生长因子的类似物 |
CN1524577A (zh) * | 2003-02-27 | 2004-09-01 | 珠海亿胜生物制药有限公司 | 碱性成纤维细胞生长因子膜剂及其制备方法 |
CN1895662A (zh) * | 2006-06-06 | 2007-01-17 | 武汉大学 | 角质细胞生长因子-2在治疗慢性宫颈炎药物中的应用 |
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2009
- 2009-11-10 CN CN 200910216184 patent/CN101721682B/zh active Active
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1169733A (zh) * | 1994-10-13 | 1998-01-07 | 安姆根有限公司 | 角化细胞生长因子的类似物 |
CN1524577A (zh) * | 2003-02-27 | 2004-09-01 | 珠海亿胜生物制药有限公司 | 碱性成纤维细胞生长因子膜剂及其制备方法 |
CN1895662A (zh) * | 2006-06-06 | 2007-01-17 | 武汉大学 | 角质细胞生长因子-2在治疗慢性宫颈炎药物中的应用 |
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