CN101721402B - 用选择性雄激素受体调节剂治疗骨相关病症 - Google Patents
用选择性雄激素受体调节剂治疗骨相关病症 Download PDFInfo
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- CN101721402B CN101721402B CN2009102541735A CN200910254173A CN101721402B CN 101721402 B CN101721402 B CN 101721402B CN 2009102541735 A CN2009102541735 A CN 2009102541735A CN 200910254173 A CN200910254173 A CN 200910254173A CN 101721402 B CN101721402 B CN 101721402B
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| US8853266B2 (en) | 2001-12-06 | 2014-10-07 | University Of Tennessee Research Foundation | Selective androgen receptor modulators for treating diabetes |
| US20070161608A1 (en) * | 2001-12-06 | 2007-07-12 | Dalton James T | Selective androgen receptor modulators for treating muscle wasting |
| US20060276539A1 (en) * | 2002-10-16 | 2006-12-07 | Dalton James T | Treating Androgen Decline in Aging Male (ADAM)- associated conditions with SARMS |
| CA2501874A1 (en) * | 2002-10-16 | 2004-04-29 | Gtx, Inc. | Treating androgen decline in aging male (adam)-associated conditions with sarms |
| US8309603B2 (en) | 2004-06-07 | 2012-11-13 | University Of Tennessee Research Foundation | SARMs and method of use thereof |
| US20110237664A1 (en) * | 2004-06-07 | 2011-09-29 | Dalton James T | Selective androgen receptor modulators for treating diabetes |
| PL1753417T3 (pl) * | 2004-06-07 | 2012-09-28 | Univ Tennessee Res Found | Selektywny modulator receptora androgenowego i jego zastosowania medyczne |
| US9884038B2 (en) | 2004-06-07 | 2018-02-06 | University Of Tennessee Research Foundation | Selective androgen receptor modulator and methods of use thereof |
| US9889110B2 (en) | 2004-06-07 | 2018-02-13 | University Of Tennessee Research Foundation | Selective androgen receptor modulator for treating hormone-related conditions |
| DK2038252T3 (en) * | 2006-07-12 | 2016-12-19 | Univ Tennessee Res Found | SUBSTITUTED AND ACYLANILIDER methods of use thereof |
| US9844528B2 (en) | 2006-08-24 | 2017-12-19 | University Of Tennessee Research Foundation | SARMs and method of use thereof |
| EP3056483A1 (en) * | 2006-08-24 | 2016-08-17 | University of Tennessee Research Foundation | Substituted acylanilides and methods of use thereof |
| US9730908B2 (en) | 2006-08-24 | 2017-08-15 | University Of Tennessee Research Foundation | SARMs and method of use thereof |
| US10010521B2 (en) | 2006-08-24 | 2018-07-03 | University Of Tennessee Research Foundation | SARMs and method of use thereof |
| PL2205552T3 (pl) * | 2007-09-11 | 2018-07-31 | Gtx, Inc. | Krystaliczny polimorf selektywnych modulatorów receptora androgenowego (R) lub (S)-N-(4-cyjano-3-(trifluorometylo)fenylo)-3-(4-cyjanofenoksy)-2-hydroksy-2-metylopropanamidu |
| US7968603B2 (en) | 2007-09-11 | 2011-06-28 | University Of Tennessee Research Foundation | Solid forms of selective androgen receptor modulators |
| US8395552B2 (en) | 2010-11-23 | 2013-03-12 | Metamagnetics, Inc. | Antenna module having reduced size, high gain, and increased power efficiency |
| WO2013152170A1 (en) * | 2012-04-04 | 2013-10-10 | Catylix, Inc. | Selective androgen receptor modulators |
| US10987334B2 (en) | 2012-07-13 | 2021-04-27 | University Of Tennessee Research Foundation | Method of treating ER mutant expressing breast cancers with selective androgen receptor modulators (SARMs) |
| US9969683B2 (en) | 2012-07-13 | 2018-05-15 | Gtx, Inc. | Method of treating estrogen receptor (ER)-positive breast cancers with selective androgen receptor modulator (SARMS) |
| US10314807B2 (en) | 2012-07-13 | 2019-06-11 | Gtx, Inc. | Method of treating HER2-positive breast cancers with selective androgen receptor modulators (SARMS) |
| US10258596B2 (en) | 2012-07-13 | 2019-04-16 | Gtx, Inc. | Method of treating HER2-positive breast cancers with selective androgen receptor modulators (SARMS) |
| US9744149B2 (en) | 2012-07-13 | 2017-08-29 | Gtx, Inc. | Method of treating androgen receptor (AR)-positive breast cancers with selective androgen receptor modulator (SARMs) |
| US9622992B2 (en) | 2012-07-13 | 2017-04-18 | Gtx, Inc. | Method of treating androgen receptor (AR)-positive breast cancers with selective androgen receptor modulator (SARMs) |
| HUE052574T2 (hu) | 2012-07-13 | 2021-05-28 | Oncternal Therapeutics Inc | Eljárás mellrákok kezelésére szelektív ösztrogén receptor modulátorral (SARM) |
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| LU88769I2 (fr) * | 1982-07-23 | 1996-11-05 | Zeneca Ltd | Bicalutamide et ses sels et esters pharmaceutiquement acceptables (Casodex (R)) |
| US6995284B2 (en) * | 2000-08-24 | 2006-02-07 | The University Of Tennessee Research Foundation | Synthesis of selective androgen receptor modulators |
| AU7604798A (en) * | 1997-05-30 | 1998-12-30 | University Of Tennessee Research Corporation, The | Non-steroidal agonist compounds and their use in male hormone therapy |
| US20020022026A1 (en) * | 1998-05-11 | 2002-02-21 | Paz Einat | Genes associated with mechanical stress, expression products therefrom, and uses thereof |
| AU2001288213B2 (en) * | 2000-06-28 | 2005-04-14 | Bristol-Myers Squibb Company | Selective androgen receptor modulators and methods for their identification, design and use |
| US20030232792A1 (en) * | 2000-08-24 | 2003-12-18 | Dalton James T. | Selective androgen receptor modulators and methods of use thereof |
| US7026500B2 (en) * | 2000-08-24 | 2006-04-11 | University Of Tennessee Research Foundation | Halogenated selective androgen receptor modulators and methods of use thereof |
| IL154425A0 (en) * | 2000-08-24 | 2003-09-17 | Univ Tennessee Res H Corp | Selective androgen receptor modulators and methods of use thereof |
| ATE344233T1 (de) * | 2000-08-24 | 2006-11-15 | Univ Tennessee Res Corp | Selektive modulatoren des andro genrezeptors und methoden zu deren verwendung |
| US6838484B2 (en) * | 2000-08-24 | 2005-01-04 | University Of Tennessee Research Foundation | Formulations comprising selective androgen receptor modulators |
| JPWO2002022585A1 (ja) * | 2000-09-14 | 2004-01-22 | 科研製薬株式会社 | テトラヒドロキノリン化合物 |
| US20030022868A1 (en) * | 2001-06-25 | 2003-01-30 | Dalton James T. | Selective androgen receptor modulators and methods of use thereof |
| AU2002330031B2 (en) * | 2001-09-21 | 2007-07-05 | Merck & Co., Inc. | Androstanes as androgen receptor modulators |
| DK1463497T3 (da) * | 2001-12-06 | 2012-01-30 | Gtx Inc | Behandling af muskelsvind med selektive androgenreceptormodulatorer |
| JP4677516B2 (ja) * | 2002-02-07 | 2011-04-27 | ユニバーシティ オブ テネシー リサーチ ファウンデーション | Ｓａｒｍを用いた前立腺肥大症治療 |
| CA2478186C (en) * | 2002-03-13 | 2011-08-23 | Merck & Co., Inc. | Fluorinated 4-azasteroid derivatives as androgen receptor modulators |
| US20040224979A1 (en) * | 2002-10-15 | 2004-11-11 | Dalton James T. | Treating obesity with selective androgen receptor modulators |
| CA2501874A1 (en) * | 2002-10-16 | 2004-04-29 | Gtx, Inc. | Treating androgen decline in aging male (adam)-associated conditions with sarms |
| CA2513242C (en) * | 2003-01-13 | 2013-07-09 | Gtx Inc. | Large-scale synthesis of selective androgen receptor modulators |
| CA2514024A1 (en) * | 2003-01-22 | 2004-08-05 | Gtx Inc. | Treating androgen deficiency in female (adif)-associated conditions with sarms |
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Non-Patent Citations (1)
| Title |
|---|
| J. Rosen, et al.Novel, non-steroidal, selective androgen receptor modulators (SARMs) with anabolic activity in bone and muscle and improved safety profile.《Journal of Musculoskeletal and Neuronal Interactions》.2002,第2卷(第3期),222-224. * |
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| CN101721402A (zh) | 2010-06-09 |
| IL172043A0 (en) | 2009-02-11 |
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| AU2004281708A1 (en) | 2005-04-28 |
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| CA2535953C (en) | 2012-07-03 |
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| EP2476415A3 (en) | 2012-08-29 |
| AU2004281708B2 (en) | 2011-02-17 |
| WO2005037201A3 (en) | 2005-10-06 |
| JP2007508386A (ja) | 2007-04-05 |
| CA2535953A1 (en) | 2005-04-28 |
| JP2010280733A (ja) | 2010-12-16 |
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