CN101720964A - Health-care drink prepared from shizandra berries - Google Patents
Health-care drink prepared from shizandra berries Download PDFInfo
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Abstract
The invention relates to a health-care drink prepared from shizandra berries, and belongs to drinks. According to a formula, the health-care drink comprises the following components in part by weight: 4.5 to 8.5 parts of shizandra berry juice, shizandra berry root extract or shizandra berry stem extract, 0.05 to 0.2 part of shizandra berry seed total lignanoid extract, 0.015 to 0.075 part of solubilizing agent and 90 to 100 parts of water. The health-care drink prepared from the shizandra berries has the advantages that: production technology is simple to operate and the health-care drink is suitable for industrialized production; the shizandra berries have very high utilization ratio and low production cost; and compared with the other drinks sold in the market, the drink prepared by the invention has high active ingredient content and odor and light bitter taste peculiar to the shizandra berries and keeps the taste of the natural shizandra berries.
Description
Technical field
The invention belongs to food, field of health care products, relate to a kind of health drink, relating in particular to a kind of is the health drink of main functional component with fruit of Chinese magnoliavine liposoluble constituent.
Background technology
The fruit of Chinese magnoliavine is Magnoliaceae fallen leaves bejucoes, fruit medicine, its flavor acid is sweet and warm in nature, clinical be mainly used in convergence astringent or styptic treatment for spontaneous sweating, promote the production of body fluid to quench thirst, antitoxic heart-soothing and sedative, hidroschesis, cough-relieving, end and losing.Because of its region kind difference, can be divided into fructus schisandrae, kadsura longepedunculata, the western fruit of Chinese magnoliavine, the main lignan component that contains, it is first-class to mainly contain schizandrin, deoxyschizandrin, schizandrin A, schisantherin, modern pharmacological research proves, the fruit of Chinese magnoliavine and alcohol extract thereof have the following aspects effect: regulate blood pressure, strengthen central nervous system excitement and process of inhibition, can be used for treating neurasthenia, amnesia.Can obviously reduce serum glutamic pyruvic transminase, acute, chronic, immunity and chemical damage are all had obvious protective effect.Tangible cough-suppressing phlegm-dispelling functions is arranged, can be used for treating respiratory disease.But the metabolism of bidirectional modulation sugar.Can strengthen humoral immunity.Have the effect of the former state of adaptation, can strengthen the resistivity of body nonspecific stimulation.Also have anti-brain damage, anti-ageing, antiulcer, effect such as antibacterial, be widely used aspect health care, being particularly suitable for often drinking, contacting for a long time chemicals has the people of hepatic injury danger and is engaged in mental work, works at night, lives irregular, valetudinarian and middle-aged and old long-term drinking for a long time.For developing this resource, the patent application of the existing multiple fructus schizandrae beverage list marketing and the multinomial parties concerned.But all the bitter principle of lignanoids has been abandoned as the harmful components that are unfavorable for mouthfeel.Conclude and get up to have two types, a kind of is the allotment processed goods of fruit juice, a kind ofly is that fruit pulverizes, add alcohol extract after, evaporation is ethanol to the greatest extent, the processing allotment forms then, since in the fruit of Chinese magnoliavine lignanoid's composition be fat-soluble in water-based beverage solubility extremely low, all separate all filterings when filtering of therefore a large amount of lignanoid's composition with the form of precipitation, cause significant wastage, thereby the lignanoid's content in the finished product is very low.Number of patent application for example: a kind of health cold-resistant schisandra fruit beverage of 93117427.9, the dried fruit of Chinese magnoliavine cleaned smash to pieces, with 50-60 degree soaking in Chinese liquor 15-20 days, extraction of the juice, remove slag, alcohol is removed in evaporation, adds flavor enhancement, anticorrisive agent, adds water and stirs, staticly settle, remove sediment, get finished product.Evaporate again after this method is extracted with liquor and remove alcohol, cause lignanoid to become fractional precipitation, remove the loss that sediment just causes lignanoid again, the waste of raw material.For juice-type beverage, because lignanoid content own is just very low in the fruit juice, thereby through after adding the water sugaring, content is just lower.For example, the Austria of selling on the market wishes the board fructus schizandrae beverage, and its functional component schizandrin, schizandrin A, deoxyschizandrin amount to and only contain 0.04mg/100ml.
Summary of the invention
The invention provides a kind of health-care drink prepared from shizandra berries, to solve the lower problem of lignanoid's content in the present health-care drink prepared from shizandra berries.The technical scheme that the present invention takes is: prescription is: comprise fruit of Chinese magnoliavine fruit juice, fruit of Chinese magnoliavine root extract or stem extract 4.5-8.5 part, fruit of Chinese magnoliavine seed total lignan extract 0.05-0.2 part, solubilizer 0.015-0.075 part, 90～100 parts in water.
In one embodiment of the present invention: the Schisandra fruit juice extraction method is: get schisandra fruit, add 4-6 times of water gaging, soaked 1-8 hour down at 40-60 degree centigrade, centrifugal by 10-80 order cloth bag, filter residue adds 4-6 times of water gaging again, soaks 1-6 hour down at 40-60 degree centigrade, and is centrifugal by 10-80 order cloth bag, with twice centrifugate mix fruit juice, adjust fruit juice concn and be every milliliter and be equivalent to fruit 0.100～0.167 gram.
In one embodiment of the present invention: the extracting method of fruit of Chinese magnoliavine seed total lignan extract is: fruit of Chinese magnoliavine seed meal is broken into meal, uses 3-6 times of solvent to press percolation or circumfluence method operation, get extract; With extract decompression and solvent recovery to solvent is 35-65%, adds the beeswax of seed weight 5-8%, puts coldly, filters oil removing; Continue then to reclaim solvent, surveying relative density during to 60 degrees centigrade is 1.10～1.25, gets the total lignan extract of fruit of Chinese magnoliavine seed.
In one embodiment of the present invention: used solubilizer is selected from Tweens or the spans in the non-ionic surface active agent.
In one embodiment of the present invention: described extraction solvent is 25%～85% methyl alcohol or ethanol.
In one embodiment of the present invention: also contain following any one or a few Chinese medical extract: genseng, pilose antler, barrenwort, American Ginseng, wilsonii, polygala root, rhodiola root, spina date seed, rose hip, sealwort, radix polygonati officinalis, the tuber of dwarf lilyturf, Momordica grosvenori, sea-buckthorn, the root of kudzu vine, Poria cocos, glossy ganoderma, the bark of eucommia, glutinous rehmannia, hoveniae semoveniae semen, pawpaw, roselle, the fruit of Cherokee rose, the seed of Oriental arborvitae, the fruit of Chinese wolfberry.
In one embodiment of the present invention: also contain a kind of or any other several compositions that to be produced in the last sweetener of accepting, anticorrisive agent, toner, antioxidant, acidity regulator, the stabilizing agent.
The purposes of a kind of health-care drink prepared from shizandra berries of the present invention, be used for to chemical damage protection, improve sleep, anti-oxidant, improve anoxia endurance, alleviating physical fatigue, auxiliary hyperglycemic, enhancing immunity.
Preparation method of the present invention is: the fruit of Chinese magnoliavine seed total lignan extract in will filling a prescription adds fruit of Chinese magnoliavine fruit juice and water and allocates with after solubilizer mixes, and filters.
The present invention has opened up the frontier that the fruit of Chinese magnoliavine is used aspect beverage, by add solubilizer and additives such as sweetener and acidity regulator provide a kind of produce total lignan content higher and the mouthfeel method of health drink preferably, improve the utilization rate of the fruit of Chinese magnoliavine, avoided the waste of the raw material and the energy.Active constituent content of the present invention is higher, and health-care effect is more obvious, and cost is lower, and mouthfeel is better, has market prospects widely.
The invention has the beneficial effects as follows: described production technology is simple to operate, is fit to suitability for industrialized production.The utilization rate of the fruit of Chinese magnoliavine is very high, and production cost is low.The beverage that this invention is made is compared with commercially available Other Drinks, the active constituent content height, and have distinctive fragrance of the fruit of Chinese magnoliavine and the light distinctive bitter taste of the fruit of Chinese magnoliavine itself, kept the taste of the natural fruit of Chinese magnoliavine.
The specific embodiment
The preparation that can add the extract of the various Chinese medicines in the beverage in following examples, these extracts can provide concrete a kind of preparation method below by the conventional method preparation of document record:
The preparation of acanthopanax senticosus extract: get wilsonii and be ground into meal for 5 kilograms, add 10 times of water gagings and decoct twice, each three hours, collecting decoction, filter 80 kilograms of acanthopanax senticosus extracts.
The preparation of Ginseng extract: get genseng and be ground into meal for 2.5 kilograms, add 8 times of amount 60% alcohol refluxs and extract twice, each 1.5 hours, merge extract, reclaim ethanol, get 12 kilograms of Ginseng extracts.
The preparation of American Ginseng extract: get American Ginseng and be ground into meal for 2.5 kilograms, add 8 times of amount 60% alcohol refluxs and extract twice, each 1.5 hours, merge extract, reclaim ethanol, get 12 kilograms of American Ginseng extracts.
The preparation of radix polygonati officinalis extract: get radix polygonati officinalis and be ground into meal for 6 kilograms, add 10 times of water gagings and decoct 3 times, each 2 hours, collecting decoction, filter 170 kilograms of radix polygonati officinalis extracts.
The preparation of rhodiola extract: get rhodiola root and be ground into meal for 3 kilograms, add 10 times and measure 70% alcohol refluxs extraction twice, each 1 hour, merge extract, filter, reclaim ethanol, get 14 kilograms of rhodiola extracts.
The preparation of root of kudzu vine extract: get the root of kudzu vine and be ground into meal for 8 kilograms, add 8 times and measure 60% alcohol refluxs extraction three times, each 1.5 hours, merge extract, filter, reclaim ethanol, get 70 kilograms of root of kudzu vine extracts.
The preparation of hoveniae semoveniae semen extract: get hoveniae semoveniae semen and be ground into meal for 3 kilograms, add 8 times of amount 50% ethanol, 80 degrees centigrade of following refluxing extraction 3 times, each 1.5 hours, merge extract, filter, reclaim ethanol, 30 kilograms of hoveniae semoveniae semen extracts.
The preparation of Radix Ophiopogonis extract: get and be ground into meal 6 kilograms of the tubers of dwarf lilyturf, add 9 times of water gagings and decoct 3 times, each 1 hour, collecting decoction, filter 160 kilograms of Radix Ophiopogonis extracts.
The preparation of roselle extract: get 4 kilograms of roselles, add 10 times of water gagings, 80 degrees centigrade of following lixiviates 3 times, each 1 hour, collecting decoction, filter 110 kilograms of roselle extracts.
The preparation of barrenwort extract: get barrenwort and be ground into meal for 6 kilograms, add 8 times of amount 80% alcohol refluxs extraction three times, each 30min merges extract, filters, and reclaims ethanol, gets 15 kilograms of barrenwort extracts.
The preparation of pilose antler extract: get pilose antler and be ground into fine powder for 0.5 kilogram, add 10 times of amount 70% alcohol refluxs and extract three times, each 1 hour, merge extract, reclaim ethanol, get 3.5 kilograms of pilose antler extracts.
The preparation of medlar extract liquid: get the fruit of Chinese wolfberry and be ground into meal for 6 kilograms, add 10 times of water gagings and decoct 3 times, each 1.5 hours, collecting decoction, filter 170 kilograms of medlar extract liquids.
The preparation of polygala root extract: get polygala root and be ground into meal for 5 kilograms, add 7 times and measure 75% alcohol refluxs extraction three times, each 1.5 hours, merge extract, filter, reclaim ethanol, get 18 kilograms of polygala root extracts.
The preparation of spina date seed extract: get spina date seed and be ground into meal for 5 kilograms, add 8 times and measure 70% alcohol refluxs extraction secondaries, each 1.5 hours, merge extract, filter, reclaim ethanol, get 20 kilograms of spina date seed extracts.
The preparation of seed of Oriental arborvitae extract: get the seed of Oriental arborvitae and be ground into meal for 5 kilograms, add 8 times and measure 70% alcohol refluxs extraction secondaries, each 1.5 hours, merge extract, filter, reclaim ethanol, get 20 kilograms of seed of Oriental arborvitae extracts.
The preparation of rose hip extract: get rose hip and be ground into meal for 5 kilograms, add 6 times and measure 75% alcohol refluxs extraction three times, each 2 hours, merge extract, filter, reclaim ethanol, get 18 kilograms of rose hip extracts.
The preparation of sealwort extract: get sealwort and be ground into meal for 6 kilograms, add 10 times of water gagings and decoct 3 times, each 2 hours, collecting decoction, filter 170 liters of sealwort extracts.
The preparation of Momordica grosvenori extract: get Momordica grosvenori and be ground into meal for 5 kilograms, add 8 times and measure 40% alcohol refluxs extraction secondaries, each 1.5 hours, merge extract, filter, reclaim ethanol, get 40 liters of Momordica grosvenori extracts.
The preparation of Poria cocos extract: get Poria cocos and be ground into meal for 6 kilograms, add 10 times of water gagings and decoct 3 times, each 1.5 hours, collecting decoction, filter 160 kilograms of Poria cocos extracts.
The preparation of lucidum extracting liquid: get glossy ganoderma and be ground into meal for 8 kilograms, add 10 times of water gagings and decoct 3 times, each 2 hours, collecting decoction, filter 220 kilograms of lucidum extracting liquids.
The preparation of bark of eucommia extract: get the bark of eucommia and be ground into meal for 6 kilograms, add 8 times and measure 50% alcohol refluxs extraction three times, each 1 hour, merge extract, filter, reclaim ethanol, get 60 kilograms of bark of eucommia extracts.
The preparation of glutinous rehmannia extract: get glutinous rehmannia and be ground into meal for 8 kilograms, add 10 times of water gagings, 60 degrees centigrade of following lixiviates 3 times, each 2 hours, collecting decoction, filter 220 kilograms of glutinous rehmannia extracts.
The preparation of pawpaw extract: get pawpaw and be ground into meal for 6 kilograms, add 10 times of water gagings, 60 degrees centigrade of following lixiviates 3 times, each 2 hours, collecting decoction, filter 170 kilograms of pawpaw extracts.
The preparation of embodiment 1 fruit of Chinese magnoliavine fruit juice:
Get 10 kilograms of schisandra fruits, add 4 times of water gagings, soaked 8 hours down at 60 degrees centigrade, centrifugal by 10 order cloth bags, filter residue adds 4 times of water gagings again, soaks 6 hours down at 60 degrees centigrade, centrifugal by 10 order cloth bags, with twice centrifugate mix fruit juice, add water and adjust fruit juice concn and be every milliliter and be equivalent to fruit 0.167 gram, altogether 60 liters of fruit juice.
Get 10 kilograms of schisandra fruits, add 5 times of water gagings, soaked 4 hours down at 50 degrees centigrade, centrifugal by 40 order cloth bags, filter residue adds 5 times of water gagings again, soaks 3 hours down at 50 degrees centigrade, centrifugal by 40 order cloth bags, with twice centrifugate mix fruit juice, add water and adjust fruit juice concn and be every milliliter and be equivalent to fruit 0.125 gram, altogether 80 liters of fruit juice.
Get 10 kilograms of schisandra fruits, add 6 times of water gagings, soaked 1 hour down at 40 degrees centigrade, centrifugal by 80 order cloth bags, filter residue adds 6 times of water gagings again, soaks 1 hour down at 40 degrees centigrade, centrifugal by 80 order cloth bags, with twice centrifugate mix fruit juice, add water and adjust fruit juice concn and be every milliliter and be equivalent to fruit 0.100 gram, altogether 100 liters of fruit juice.
The preparation of the total lignan extract of embodiment 2 fruit of Chinese magnoliavine seeds
Get 1.8 kilograms in seed, seed meal is broken into meal, press the percolation operation: soaked into 24 hours with 3 times of amount 75% ethanol, the dress percolator adds 75% ethanol, opens following valve and begins diacolation, and regulating flow velocity is every kg p m 3ml, collects 4 liters of percolates; The percolate decompression recycling ethanol to containing alcohol amount 35%, is added the beeswax of seed weight 5%, put coldly, filter oil removing.Surveying relative density when continue reclaiming ethanol to 60 degree centigrade then is 1.10～1.25, the total lignan extract of fruit of Chinese magnoliavine seed.
Get 1.8 kilograms in seed, seed meal is broken into meal, press the percolation operation: soaked into 24 hours with 5 times of amount 75% ethanol, the dress percolator adds 75% ethanol, opens following valve and begins diacolation, and regulating flow velocity is every kg p m 4ml, collects 5 liters of percolates; The percolate decompression recycling ethanol to containing alcohol amount 50%, is added the beeswax of seed weight 7%, put coldly, filter oil removing.Surveying relative density when continue reclaiming ethanol to 60 degree centigrade then is 1.10～1.25, the total lignan extract of fruit of Chinese magnoliavine seed.
Get 1.8 kilograms in seed, seed meal is broken into meal, press the percolation operation: soaked into 24 hours with 6 times of amount 75% ethanol, the dress percolator adds 75% ethanol, opens following valve and begins diacolation, and regulating flow velocity is every kg p m 5ml, collects 6 liters of percolates; The percolate decompression recycling ethanol to containing alcohol amount 65%, is added the beeswax of seed weight 8%, put coldly, filter oil removing.Surveying relative density when continue reclaiming ethanol to 60 degree centigrade then is 1.10～1.25, the total lignan extract of fruit of Chinese magnoliavine seed.
Embodiment 3: the preparation of the extract of fruit of Chinese magnoliavine root
Get 10 kilograms of fruit of Chinese magnoliavine roots, be ground into meal, press the percolation operation: soaked into 24 hours with 3 times of amount 85% ethanol, the dress percolator adds 85% ethanol, opens following valve and begins diacolation, and regulating flow velocity is every kg p m 3ml, collects 20 liters of percolates.To there not being alcohol, surveying relative density when being concentrated into 60 degrees centigrade is 1.10～1.25 with the percolate decompression recycling ethanol, gets the extract of fruit of Chinese magnoliavine root.
Get 10 kilograms of fruit of Chinese magnoliavine roots, be ground into meal, press the percolation operation: soaked into 24 hours with 5 times of amount 25% ethanol, the dress percolator adds 25% ethanol, opens following valve and begins diacolation, and regulating flow velocity is every kg p m 4ml, collects 30 liters of percolates.To there not being alcohol, surveying relative density when being concentrated into 60 degrees centigrade is 1.10～1.25 with the percolate decompression recycling ethanol, gets the extract of fruit of Chinese magnoliavine root.
Get 10 kilograms of fruit of Chinese magnoliavine roots, be ground into meal, press the percolation operation: soaked into 24 hours with 6 times of amount 25% methyl alcohol, the dress percolator adds 25% methyl alcohol, opens following valve and begins diacolation, and regulating flow velocity is every kg p m 5ml, collects 40 liters of percolates.To there not being alcohol, surveying relative density when being concentrated into 60 degrees centigrade is 1.10～1.25 with percolate recovered under reduced pressure methyl alcohol, gets the extract of fruit of Chinese magnoliavine root.
The preparation of the extract of embodiment 4 five tastes blastostyles
Get 10 kilograms of five tastes blastostyles, be ground into meal, press the percolation operation: soaked into 24 hours with 3 times of amount 85% methyl alcohol, the dress percolator adds 85% methyl alcohol, opens following valve and begins diacolation, and regulating flow velocity is every kg p m 3ml, collects 20 liters of percolates.To there not being alcohol, surveying relative density when being concentrated into 60 degrees centigrade is 1.10～1.25 with percolate recovered under reduced pressure methyl alcohol, gets the extract of five tastes blastostyle.
Get 10 kilograms of five tastes blastostyles, be ground into meal, press the percolation operation: soaked into 24 hours with 4 times of amount 75% methyl alcohol, the dress percolator adds 75% methyl alcohol, opens following valve and begins diacolation, and regulating flow velocity is every kg p m 4ml, collects 30 liters of percolates.To there not being alcohol, surveying relative density when being concentrated into 60 degrees centigrade is 1.10～1.25 with percolate recovered under reduced pressure methyl alcohol, gets the extract of five tastes blastostyle.
Get 10 kilograms of five tastes blastostyles, be ground into meal, press the percolation operation: soaked into 24 hours with 6 times of amount 55% methyl alcohol, the dress percolator adds 55% methyl alcohol, opens following valve and begins diacolation, and regulating flow velocity is every kg p m 5ml, collects 40 liters of percolates.To there not being alcohol, surveying relative density when being concentrated into 60 degrees centigrade is 1.10～1.25 with percolate recovered under reduced pressure methyl alcohol, gets the extract of five tastes blastostyle.
Below among each embodiment total lignan extract, fruit of Chinese magnoliavine fruit juice, fruit of Chinese magnoliavine root extract, the five tastes blastostyle extract of used fruit of Chinese magnoliavine seed be that above each embodiment method makes.
Embodiment 5
Get the total lignan extract 0.05kg of fruit of Chinese magnoliavine seed, stir and to add the 0.015kg Tween-80 down, continue to stir 1-10 minute then, stir and add fruit of Chinese magnoliavine fruit juice 4.5kg down, add purified water 90kg then, filter, check, can, promptly.
Get the total lignan extract 0.125kg of fruit of Chinese magnoliavine seed, stir and to add the 0.045kg Tween-80 down, continue to stir 1-10 minute then, stir and add fruit of Chinese magnoliavine fruit juice 6.5kg down, add purified water 95kg then, filter, check, can, promptly.
Get the total lignan extract 0.2kg of fruit of Chinese magnoliavine seed, stir and to add the 0.075kg Tween-80 down, continue to stir 1-10 minute then, stir and add fruit of Chinese magnoliavine fruit juice 8.5kg down, add purified water 100kg then, filter, check, can, promptly.
Get the total lignan extract 0.05kg of fruit of Chinese magnoliavine seed, stir and to add the 0.015kg Arlacel-80 down, continue to stir 1-10 minute then, stir and add fruit of Chinese magnoliavine root extract 4.5kg down, add purified water 90kg then, filter, check, can, promptly.
Get the total lignan extract 0.125kg of fruit of Chinese magnoliavine seed, stir and to add the 0.045kg Arlacel-80 down, continue to stir 1-10 minute then, stir and add fruit of Chinese magnoliavine root extract 6.5kg down, add purified water 95kg then, filter, check, can, promptly.
Get the total lignan extract 0.2kg of fruit of Chinese magnoliavine seed, stir and to add the 0.075kg Arlacel-80 down, continue to stir 1-10 minute then, stir and add fruit of Chinese magnoliavine root extract 8.5kg down, add purified water 100kg then, filter, check, can, promptly.
Get the total lignan extract 0.05kg of fruit of Chinese magnoliavine seed, stir and to add the 0.015kg Arlacel-80 down, continue to stir 1-10 minute then, stir and add five tastes blastostyle extract 4.5kg down, add purified water 90kg then, filter, check, can, promptly.
Get the total lignan extract 0.125kg of fruit of Chinese magnoliavine seed, stir and to add the 0.045kg Arlacel-80 down, continue to stir 1-10 minute then, stir and add five tastes blastostyle extract 6.5kg down, add purified water 95kg then, filter, check, can, promptly.
Get the total lignan extract 0.2kg of fruit of Chinese magnoliavine seed, stir and to add the 0.075kg Arlacel-80 down, continue to stir 1-10 minute then, stir and add five tastes blastostyle extract 8.5kg down, add purified water 100kg then, filter, check, can, promptly.
Embodiment 6
Get the total lignan extract 0.05kg of fruit of Chinese magnoliavine seed, stir and to add the 0.015kg Tween-80 down, continue to stir 1-10 minute then, stir and add fruit of Chinese magnoliavine fruit juice 4.5kg down, add Aspartame 0.06kg, add purified water 90kg then, filter, check, can, promptly.
Get the total lignan extract 0.125kg of fruit of Chinese magnoliavine seed, stir and to add the 0.045kg Tween-80 down, continue to stir 1-10 minute then, stir and add fruit of Chinese magnoliavine fruit juice 6.5kg down, add Aspartame 0.09kg, add purified water 95kg then, filter, check, can, promptly.
Get the total lignan extract 0.2kg of fruit of Chinese magnoliavine seed, stir and to add the 0.075kg Tween-80 down, continue to stir 1-10 minute then, stir and add fruit of Chinese magnoliavine fruit juice 8.5kg down, add Aspartame 0.12kg, add purified water 100kg then, filter, check, can, promptly.
Embodiment 7
Get the total lignan extract 0.05kg of fruit of Chinese magnoliavine seed, stir and add the 0.015kg Arlacel-80 down, continue to stir 1-10 minute then, stir and add fruit of Chinese magnoliavine root extract 4.5kg down, add Aspartame 0.06kg, potassium sorbate 0.02kg adds purified water 90kg then, filters check, can, promptly.
Get the total lignan extract 0.125kg of fruit of Chinese magnoliavine seed, stir and add the 0.045kg Arlacel-80 down, continue to stir 1-10 minute then, stir and add fruit of Chinese magnoliavine root extract 6.5kg down, add Aspartame 0.09kg, potassium sorbate 0.03kg adds purified water 95kg then, filter, check, can, promptly.
Get the total lignan extract 0.2kg of fruit of Chinese magnoliavine seed, stir and add the 0.075kg Arlacel-80 down, continue to stir 1-10 minute then, stir and add fruit of Chinese magnoliavine root extract 8.5kg down, add Aspartame 0.12kg, potassium sorbate 0.04kg adds purified water 100kg then, filter, check, can, promptly.
Embodiment 8
Get the total lignan extract 0.05kg of fruit of Chinese magnoliavine seed, stir and add the 0.015kg Arlacel-80 down, continue to stir 1-10 minute then, stir and add five tastes blastostyle extract 4.5kg down, add Aspartame 0.06kg, potassium sorbate 0.02kg, add vitamin C 0.02kg, add purified water 90kg then, filter, check, can, promptly.
Get the total lignan extract 0.125kg of fruit of Chinese magnoliavine seed, stir and add the 0.045kg Arlacel-80 down, continue to stir 1-10 minute then, stir and add five tastes blastostyle extract 6.5kg down, add Aspartame 0.09kg, potassium sorbate 0.03kg, add vitamin C 0.03kg, add purified water 95kg then, filter, check, can, promptly.
Get the total lignan extract 0.2kg of fruit of Chinese magnoliavine seed, stir and add the 0.075kg Arlacel-80 down, continue to stir 1-10 minute then, stir and add five tastes blastostyle extract 8.5kg down, add Aspartame 0.12kg, potassium sorbate 0.04kg adds purified water 100kg then, adding vitamin C 0.04kg filters, check, can, promptly.
Embodiment 9
Get the total lignan extract 0.05kg of fruit of Chinese magnoliavine seed, stir and to add the 0.015kg Tween-80 down, continue to stir 1-10 minute then, stir and add fruit of Chinese magnoliavine fruit juice 4.5kg down, Ginseng extract 1kg adds purified water 90kg then, filters, check, can, promptly.
Get the total lignan extract 0.125kg of fruit of Chinese magnoliavine seed, stir and to add the 0.045kg Tween-80 down, continue to stir 1-10 minute then, stir and add fruit of Chinese magnoliavine fruit juice 6.5kg down, American Ginseng extract 1kg adds purified water 95kg then, filters, check, can, promptly.
Get the total lignan extract 0.2kg of fruit of Chinese magnoliavine seed, stir and to add the 0.075kg Tween-80 down, continue to stir 1-10 minute then, stir and add fruit of Chinese magnoliavine fruit juice 8.5kg down, add acanthopanax senticosus extract 8kg, add purified water 100kg then, filter, check, can, promptly.
Get the total lignan extract 0.05kg of fruit of Chinese magnoliavine seed, stir and add the 0.015kg Arlacel-80 down, continue to stir 1-10 minute then, stir and add fruit of Chinese magnoliavine root extract 4.5kg down, add radix polygonati officinalis extract 17kg, rhodiola extract 1.4kg adds purified water 90kg then, filter, check, can, promptly.
Get the total lignan extract 0.125kg of fruit of Chinese magnoliavine seed, stir and add the 0.045kg Arlacel-80 down, continue to stir 1-10 minute then, stir and add fruit of Chinese magnoliavine root extract 6.5kg down, add hoveniae semoveniae semen extract 3kg, root of kudzu vine extract 7kg adds purified water 95kg then, filter, check, can, promptly.
Get the total lignan extract 0.2kg of fruit of Chinese magnoliavine seed, stir and add the 0.075kg Arlacel-80 down, continue to stir 1-10 minute then, stir and add fruit of Chinese magnoliavine root extract 8.5kg down, add and extract 16kg the tuber of dwarf lilyturf, add roselle extract 11kg, barrenwort extract 15kg, add purified water 100kg then, filter, check, can, promptly.
Get the total lignan extract 0.05kg of fruit of Chinese magnoliavine seed, stir and to add the 0.015kg Arlacel-80 down, continue to stir 1-10 minute then, stir and add five tastes blastostyle extract 4.5kg down, add pilose antler extract pilose antler extract 0.35kg, medlar extract liquid 17kg, polygala root extract 1.8kg, spina date seed extract 2kg, seed of Oriental arborvitae extract 2kg, add purified water 90kg then, filter, check, can, promptly.
Get the total lignan extract 0.125kg of fruit of Chinese magnoliavine seed, stir and to add the 0.045kg Arlacel-80 down, continue to stir 1-10 minute then, stir and add five tastes blastostyle extract 6.5kg, rose hip extract 1.8kg down, sealwort extract 17kg, Momordica grosvenori extract 4kg, Poria cocos extract 16kg adds purified water 95kg then, filter, check, can, promptly.
Get the total lignan extract 0.2kg of fruit of Chinese magnoliavine seed, stir and to add the 0.075kg Arlacel-80 down, continue to stir 1-10 minute then, stir and add five tastes blastostyle extract 8.5kg, lucidum extracting liquid 22kg down, bark of eucommia extract 6kg, glutinous rehmannia extract 22kg, pawpaw extract 17kg adds purified water 100kg then, filter, check, can, promptly.
Embodiment 10
Get the total lignan extract 0.05kg of fruit of Chinese magnoliavine seed, stir and to add the 0.015kg Tween-80 down, continue to stir 1-10 minute then, stir and add fruit of Chinese magnoliavine fruit juice 4.5kg, Ginseng extract 1kg down, add Aspartame 0.06kg, add purified water 90kg then, filter, check, can, promptly.
Get the total lignan extract 0.125kg of fruit of Chinese magnoliavine seed, stir and to add the 0.045kg Tween-80 down, continue to stir 1-10 minute then, stir and add fruit of Chinese magnoliavine fruit juice 6.5kg down, American Ginseng extract 1kg, adds purified water 95kg then at acesulfame potassium 0.06kg, filters, check, can, promptly.
Get the total lignan extract 0.2kg of fruit of Chinese magnoliavine seed, stir and to add the 0.075kg Tween-80 down, continue to stir 1-10 minute then, stir and add fruit of Chinese magnoliavine fruit juice 8.5kg down, add acanthopanax senticosus extract 8kg, add sucrose 10kg, add purified water 100kg then, filter, check, can, promptly.
Get the total lignan extract 0.05kg of fruit of Chinese magnoliavine seed, stir and to add the 0.015kg Arlacel-80 down, continue to stir 1-10 minute then, stir and add fruit of Chinese magnoliavine root extract 4.5kg down, add radix polygonati officinalis extract 17kg, rhodiola extract 1.4kg, add Aspartame 0.06kg, potassium sorbate 0.02kg adds purified water 90kg then, filter, check, can, promptly.
Get the total lignan extract 0.125kg of fruit of Chinese magnoliavine seed, stir and to add the 0.045kg Arlacel-80 down, continue to stir 1-10 minute then, stir and add fruit of Chinese magnoliavine root extract 6.5kg down, add hoveniae semoveniae semen extract 3kg, root of kudzu vine extract 7kg, add Aspartame 0.07kg, Sodium Benzoate 0.02kg adds purified water 95kg then, filter, check, can, promptly.
Get the total lignan extract 0.2kg of fruit of Chinese magnoliavine seed, stir and to add the 0.075kg Arlacel-80 down, continue to stir 1-10 minute then, stir and add fruit of Chinese magnoliavine root extract 8.5kg down, add and extract 16kg the tuber of dwarf lilyturf, add roselle extract 11kg, barrenwort extract 15kg adds Aspartame 0.07kg, Sodium Benzoate 0.02kg, add purified water 100kg then, filter, check, can, promptly.
Get the total lignan extract 0.05kg of fruit of Chinese magnoliavine seed, stir and to add the 0.015kg Arlacel-80 down, continue to stir 1-10 minute then, stir and add five tastes blastostyle extract 4.5kg down, add pilose antler extract pilose antler extract 0.35kg, medlar extract liquid 17kg, polygala root extract 1.8kg, spina date seed extract 2kg, seed of Oriental arborvitae extract 2kg adds Aspartame 0.07kg, Sodium Benzoate 0.02kg, vitamin C 0.02kg adds purified water 90kg then, filter, check, can, promptly.
Get the total lignan extract 0.125kg of fruit of Chinese magnoliavine seed, stir and to add the 0.045kg Arlacel-80 down, continue to stir 1-10 minute then, stir and add five tastes blastostyle extract 6.5kg down, rose hip extract 1.8kg, sealwort extract 17kg, Momordica grosvenori extract 4kg, Poria cocos extract 16kg adds Aspartame 0.07kg, Sodium Benzoate 0.02kg, vitamin C 0.02kg, add purified water 95kg then, filter, check, can, promptly.
Get the total lignan extract 0.2kg of fruit of Chinese magnoliavine seed, stir and to add the 0.075kg Arlacel-80 down, continue to stir 1-10 minute then, stir and add five tastes blastostyle extract 8.5kg down, lucidum extracting liquid 22kg, bark of eucommia extract 6kg, glutinous rehmannia extract 22kg, pawpaw extract 17kg adds Aspartame 0.07kg, Sodium Benzoate 0.02kg, vitamin C 0.02kg, add purified water 100kg then, filter, check, can, promptly.
Embodiment 11
Get the total lignan extract 140g of fruit of Chinese magnoliavine seed, stir and add the 75g Tween-80 down, continue to stir to stir then in 1-10 minute and add Ginseng extract 1200g, radix polygonati officinalis extract 17000g down, fruit of Chinese magnoliavine fruit juice 8000g adds Catergen 0g, natrium citricum 18g, citric acid 27g, potassium sorbate 30g, acesulfame potassium 11g, Aspartame 11g then, adds purified water then to 80kg, filter, check, can, promptly.
Embodiment 12
Get the total lignan extract 112g of fruit of Chinese magnoliavine seed, stir and add the 15g Tween-80 down, continue to stir to stir then in 1-10 minute and add polygala root extract 1.8kg, fruit of Chinese magnoliavine fruit juice 6.4kg down, add Catergen 0g, amaranth 1.5g, natrium citricum 18g, citric acid 27g, malic acid 9g, potassium sorbate 30g, Aspartame 60g then, add purified water then to 60kg, filter, can, promptly.
Embodiment 13
Get the total lignan extract 168g of fruit of Chinese magnoliavine seed, stir and add 75 gram Tween-80s down, continue to stir to stir then in 1-10 minute and add rhodiola extract 14kg, fruit of Chinese magnoliavine fruit juice 96kg down, add Catergen 00g, natrium citricum 180g, citric acid 270g, potassium sorbate 300g, Aspartame 1500g then, add purified water then to 900kg, filter, check, can, promptly.
Embodiment 14
Get the total lignan extract 1400g of fruit of Chinese magnoliavine seed, stir and add the 700g Tween-80 down, continue to stir to stir then in 1-10 minute and add hoveniae semoveniae semen extract 30g, fruit of Chinese magnoliavine fruit juice 80g down, add Catergen 00g, amaranth 15g, potassium sorbate 300g, acesulfame potassium 100g, Aspartame 100g, sucrose 30kg, xanthans 200g then, add purified water then to 900g, filter, check, can, promptly.
Confirm the purposes of health-care drink prepared from shizandra berries below by concrete effect experiment
Test the influence of a five tastes seed extract to mouse sleep time
The present invention with embodiment 5 gained carries out following experiment: adopt the fruit juice group.
Experimental technique: get totally 60 of body weight 21-25g male and female mouse, divide 3 groups at random, 20 every group.1, blank group (with the isopyknic physiological saline of administration group) n=20; 2, stable group (2mg/kg body weight) n=20; 3, of the present invention group (2mg/kg body weight) n=20;
Test procedure and observation index: after each treated animal is pressed above-mentioned dosage gastric infusion 45min, lumbar injection threshold dose yellow Jackets (0.6mg/10g), the length of one's sleep of observation and record mouse.With the righting reflex loss is time for falling asleep, and the time of recovering from righting reflex loss to righting reflex is sleep time.
Table 1 the present invention is to the influence of mouse sleep time
| Group | Dosage (mg/kg) | Number of animals | Activity change rate (min) (x ± SD) | The P value |
| The blank group | ??0 | ??20 | ??42.46±13.12 | ??-- |
| Stable group | ??2 | ??20 | ??54.68±15.13 | ??P＜0.01 |
| Of the present invention group | ??50 | ??20 | ??52.43±16.64 | ??P＜0.05 |
As can be seen from Table 1: of the present invention group all can prolong the length of one's sleep of yellow Jackets mouse with stable, compare with control group, of the present invention group on average prolongs 10min, the average 12min that prolongs of stable group, compare with control group, the influence of the present invention, the stable length of one's sleep to the yellow Jackets mouse has statistical significance through the t check, illustrate that the present invention and An all have the prolongation effect of the length of one's sleep to the yellow Jackets mouse.
Test the effect of two the present invention to the carbon tetrachloride hepatic injury mouse
The present invention with embodiment 5 gained carries out following experiment.
Experimental technique: get 100 of body weight 21-25g male and female mouse and be divided into five groups at random, be respectively normal control group, carbon tetrachloride model group, health-care drink prepared from shizandra berries (fruit) group, health-care drink prepared from shizandra berries (root) group, health-care drink prepared from shizandra berries (stem) group.Except that the normal control group, the carbon tetrachloride corn oil solution (10ml/kg) of every group of first day lumbar injection 0.2% is gastric infusion 15 days simultaneously continuously, and after the last administration 16 hours, eye socket was got blood, surveys serum glutamic pyruvic transminase (SGPT), and the result is as follows:
Table 2 the present invention is to the influence of carbon tetrachloride hepatic injury mouse
| Group (n=20) | Dosage (mg/kg) | SGPT content (U/ml) |
| The normal control group | ??166,8±25.26. | |
| The carbon tetrachloride model group | ??446.7±37.32 | |
| Health-care drink prepared from shizandra berries (fruit) group, | ??1200 | ??280.2±29.49 |
| Health-care drink prepared from shizandra berries (root) group, | ??1200 | ??279.8±35.34 |
| Health-care drink prepared from shizandra berries (stem) group, | ??1200 | ??268.89±65.53 |
Conclusion carbon tetrachloride group mouse SPGT content is significantly higher than the normal control group, P＜0.01.Compare with the carbon tetrachloride group, health-care drink prepared from shizandra berries (fruit) group, health-care drink prepared from shizandra berries (root) group, health-care drink prepared from shizandra berries (stem) group SPGT content significantly reduce, and P＜0.01. explanation health-care drink prepared from shizandra berries has significant inhibitory effect to the rising of the mouse SPGT of carbon tetrachloride hepatic injury.
Claims (7)
1. a health-care drink prepared from shizandra berries is characterized in that prescription is: comprise fruit of Chinese magnoliavine fruit juice, fruit of Chinese magnoliavine root extract or stem extract 4.5-8.5 part, fruit of Chinese magnoliavine seed total lignan extract 0.05-0.2 part, solubilizer 0.015-0.075 part, 90～100 parts in water.
2. a kind of health-care drink prepared from shizandra berries according to claim 1 is characterized in that:
(1) the Schisandra fruit juice extraction method is: get schisandra fruit, add 4-6 times of water gaging, soaked 1-8 hour down at 40-60 degree centigrade, centrifugal by 10-80 order cloth bag, filter residue adds 4-6 times of water gaging again, soaks 1-6 hour down at 40-60 degree centigrade, and is centrifugal by 10-80 order cloth bag, with twice centrifugate mix fruit juice, adjust fruit juice concn and be every milliliter and be equivalent to fruit 0.100～0.167 gram.
(2) extracting method of fruit of Chinese magnoliavine seed total lignan extract is: fruit of Chinese magnoliavine seed meal is broken into meal, uses 3-6 times of solvent to press percolation or circumfluence method operation, get extract; With extract decompression and solvent recovery to solvent is 35-65%, adds the beeswax of seed weight 5-8%, puts coldly, filters oil removing; Continue then to reclaim solvent, surveying relative density during to 60 degrees centigrade is 1.10～1.25, gets the total lignan extract of fruit of Chinese magnoliavine seed.
3. a kind of health-care drink prepared from shizandra berries according to claim 1 is characterized in that: used solubilizer is selected from Tweens or the spans in the non-ionic surface active agent.
4. a kind of health-care drink prepared from shizandra berries according to claim 2 is characterized in that: described extraction solvent is 25%～85% methyl alcohol or ethanol.
5. a kind of health-care drink prepared from shizandra berries according to claim 1 is characterized in that: also contain following any one or a few Chinese medical extract: genseng, pilose antler, barrenwort, American Ginseng, wilsonii, polygala root, rhodiola root, spina date seed, rose hip, sealwort, radix polygonati officinalis, the tuber of dwarf lilyturf, Momordica grosvenori, the root of kudzu vine, Poria cocos, glossy ganoderma, the bark of eucommia, glutinous rehmannia, hoveniae semoveniae semen, pawpaw, roselle, the fruit of Cherokee rose, the seed of Oriental arborvitae, the fruit of Chinese wolfberry.
6. a kind of health-care drink prepared from shizandra berries that require according to claim 1 or 5 is characterized in that: also contain to be produced and go up a kind of in the sweetener accepted, anticorrisive agent, toner, antioxidant, acidity regulator, the stabilizing agent or other several compositions arbitrarily.
7. as the purposes of claim 1 or 5 or 6 described a kind of health-care drink prepared from shizandra berries, it is characterized in that: be used for to chemical damage protection, improve sleep, anti-oxidant, improve anoxia endurance, alleviating physical fatigue, auxiliary hyperglycemic, enhancing immunity.
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