CN101700397B - Tibetan medicine composite for treating diabetes and preparation method of preparation thereof - Google Patents
Tibetan medicine composite for treating diabetes and preparation method of preparation thereof Download PDFInfo
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Abstract
The invention relates to a Tibetan medicine composite for treating diabetes, comprising the following components: 4.8-7.2g of medicine terminalia fruit, 2.4-3.6g of Chaxun ointment, 4-6g of long pepper extract, 3.2-4.8g of bright salt, 4.8-7.2g of trona, 2.4-3.6g of costustoot, 4-6g of fructus coriandri sativi, 2.4-3.6g of Tibet inula root, 4.8-7.2g of round cardamom, 4-6g of dried ginger, 2.4-3.6 cortex cinnamomi, 4-6g of red flower, 4-6g of savoury rhododendron leaf, 1.6-2.4g of pomegranate seed, 2.4-3.6g of rhubarb, 0.8-1.2g of purpurea halitium, 0.8-1.2g of flos caryophyllata, 4-6g of fructus terminaliae billericae, 1.6-2.4g of Shaji ointment, 2.4-3.6g of emblic leafflower fruit, 0.8-1.2g of crocus sativus, 0.8-1.2g of bear gall, 4-6g of fructus tsaoko, 4-6g of siberian solomonseal rhizome, 2.4-3.6g of puncturevine caltrop fruit, 4.8-7.2g of embelia laeta, 7.4-9.6g of herba dracocephali tangutici, and 7.4-9.6g of tinospora sinensis. The Tibetan medicine composite of the invention has significant clinical efficacy, little toxic and side effects and simple and convenient preparation.
Description
Technical field
The present invention relates to a kind of Tibetan medicine composition and method of making the same, particularly a kind of Tibetan medicine composition and method of making the same for the treatment of diabetes.
Background technology
Diabetes are to act on that body causes hypoinsulinism, insulin resistant etc. and a series of metabolism disorder syndromes such as the sugar that causes, protein, fat, power and water Xie Zhi by inherited genetic factors, immunologic function disorder, infected by microbes and toxin thereof, free radical toxin, Nervous and Mental Factors or the like various virulence factors, be main feature clinically with the hyperglycemia, performance such as polyuria, polydipsia, polyphagia can appear in model case, become thin, i.e. " three-many-one-little " symptom.
The name of disease of diabetes in Chinese medicine is diabetes, be meant with polydipsia, polyuria, polyphagia and become thin, tired, urine sweet be the comprehensive disease of principal character.Tibetan medicine's pharmacy is the rarity in motherland's traditional medicine treasure-house.Kept westerly since the history, in very long social development, Tibetan people has accumulated and has grasped the method for abundant self health care and treatment various diseases in the process of struggling with nature and disease.From the symptom and the character of diabetes, it belongs to " Jing Nisagu " disease of Tibetanmedicine, the general translations of Chinese " urine eliminating mass ".About " Jing Nisagu ", detailed record is just arranged in the Four-Volume Medical Code: " ' Jing Nisagu ' its disease is seen: weak drowsiness; hyperhidrosis and companion's abnormal flavour; become thin; hair and onyx are uninteresting simple and unadorned, and normal sense sweet taste and oropharynx are extremely dried in mouthful, have a liking for cold drink; the dysphoria with feverish sensation in the chest palms and soles urine is turbid, and urine mark place often has insecticide such as Apis to assemble.If the above symptom of tool singly then can not assert disease for this reason with the pure and impure of urine." above symptom and the symptom of today " diabetes " be very identical, so the Tibetan medicine has special curative effect to the treatment of this disease.
Modern medicine has had further understanding to diabetes and treatment thereof, but does not also form a kind of effective Therapeutic Method so far.Though in recent years problem on many etiology such as hormone of genetic problem, viral infection, autoimmune and antagonism insulin is studied still weary so far etiological treatment measure.The life-time service Western medicine can produce toxic and side effects and drug resistance, and the treatment cost is also than higher.So the utilization traditional medicine is carried out dialectical to diabetes, therefrom seek treatment of diabetes and rehabilitation and might as well be a kind of method.
Summary of the invention
The present invention is intended to overcome above-mentioned defective, and a kind of conventional medicament compositions for the treatment of diabetes is provided, particularly a kind of Tibetan medicine compositions for the treatment of diabetes.This medicine kidney tonifying, diuresis.Be used for frequent micturition and sweet, urgent micturition, nephropathy, emaciated physique, spiritlessness and weakness, the higher person of blood glucose that diabetes are caused has hypoglycemic activity especially, good effect, toxic and side effects is little, low production cost.
For achieving the above object, the concrete technical scheme of the present invention is as follows:
A kind of Tibetan medicine compositions for the treatment of diabetes is characterized in that it comprises that the component by following weight proportion constitutes:
Fructus Chebulae 4.8～7.2g Fructus Hippophae cream 2.4～3.6g Fructus Piperis Longi 4～6g natural salt 3.2～4.8g
Trona 4.8～7.2g Radix Aucklandiae 2.4～3.6g Fructus Coriandri sativi 4～6g Radix Inulae 2.4～3.6g
Fructus Amomi Rotundus 4.8～7.2g Rhizoma Zingiberis 4～6g Cortex Cinnamomi 2.4～3.6g Flos Carthami 4～6g
The purple Sal Ammoniacus 0.8～1.2g of Rhododendron 4～6g Semen Granati 1.6～2.4g Radix Et Rhizoma Rhei 2.4～3.6g
Flos Caryophylli 0.8～1.2g Fructus Terminaliae Billericae 4～6g Fructus Hippophae extractum 1.6～2.4g Fructus Phyllanthi 2.4～3.6g
Stigma Croci 0.8～1.2g Fel Ursi 0.8～1.2g Fructus Tsaoko 4～6g Rhizoma Polygonati 4～6g
Fructus Tribuli 2.4～3.6g Fructus embeliae laetae 4.8～7.2g tangut dragonhead 7.4～9.6g Herba Lycopodii 7.4～9.6g.
Described Fructus Hippophae cream be Fructus Hippophae through soaking, boil dissolving, filter, discard filtering residue, filtrate again through concentrating paste.
Described Fructus Hippophae extractum is Fructus Hippophae is concocted gained through routine a paste.
Described Fel Ursi is a made powder behind the clean epithelium.
According to " Chinese herbal Tibetan medicine volume " record, above-mentioned 28 flavor medicines in Tibetan medicine's theory nature and flavor, effect and cure mainly into:
(1) Fructus Chebulae (Tibetan language name: A Rure): puckery, property is flat.Nourishing takes care of health, and rises stomach-fire, and is aid digestion, comfortable, makes eye bright.Cure mainly the disease that " dragon ", " red crust ", " Baconic " bring out.
(2) Fructus Hippophae cream (ochotona erythrotis redeared pika feces, Tibetan language name: Fructus Hippophae): sweet in the mouth, hardship, cool in nature.Heat clearing away, antiinflammatory.Cure mainly gastric heat, intestinal heat, liver-heat, kidney-heat and " wooden cloth ", oculopathy etc.
(3) (Tibetan language name: Bi Bilin): acrid in the mouth, digestion is bitter in the mouth afterwards, and is warm in nature for Fructus Piperis Longi.Warming spleen and stomach for dispelling cold, the therapeutic method to keep the adverse QI flowing downwards helps digestion.Cure mainly cold " dragon " disease, " Baconic " disease, cold syndrome of the stomach, renal cold, various sympotoms caused by cold factors such as sexual impotence.
(4) natural salt (Tibetan language name: add and examine): salty in the mouth, sweet, warm in nature.Removing trembles with fear is good for the stomach wind dispelling.Cure mainly the complication of cold " Baconic ", " dragon ", the dyspepsia that cold syndrome of the stomach causes.
(5) trona (the Tibetan language name: take by force the shop): bitter in the mouth, sweet, salty, warm in nature.Aid digestion.Cure mainly gastric ulcer, " Baconic " property flatulence, parasitosis, toxic hepatic disease.
(6) Radix Aucklandiae (Tibetan language name: as reach): acrid in the mouth, hardship, warm in nature.Stomach warming, broken painful abdominal mass knot, granulation promoting.Cure mainly the flatulence pain, " dragon " disease, disorders of blood, diphtheria, pneumonopathy, " Baconic " is poly-to stagnate, diarrhea of heat type, the open sore part is not held back.
(7) Fructus Coriandri sativi (the Tibetan language name: I revives): acrid in the mouth, salty, digestion back bitter in the mouth, cool in nature and light, profit.Clearing away heat and expelling pathogen in the exterior is good for the stomach.Cure mainly " Baconic's wood cloth " disease, dyspepsia, inappetence, thirsty, gastrointestinal angor, infantile measles.
(8) Radix Inulae (Radix Inulae, the Tibetan language name: the agate slave clings to bundle): acrid in the mouth, hardship, digestion back sweet in the mouth, warm in nature.Strong skin stomach function regulating, promoting the flow of QI for relieving the stagnancy, pain relieving.Cure mainly wind blood hand over anti-, backache, " wooden cloth " disease makes outside the plague fever of hiding shows.
(9) Fructus Amomi Rotundus (Fructus Amomi Rotundus, Tibetan language name: add Na Sumen): sweet in the mouth, suffering, warm in nature.Invigorating the stomach and promoting digestion, warming the kidney to invigorate YANG.Cure mainly cold gastropathy, the waist and leg ache that renal cold causes, frequent micturition or urine retention, renal failure etc.
(10) Rhizoma Zingiberis (the Tibetan language name: loud, high-pitched sound adds): acrid in the mouth, warm in nature.The cold expelling that induces sweat, preventing phlegm from forming and stopping coughing, promoting flow of QI and blood.Cure mainly anemofrigid cold, cold-phlegm cough, blood stagnation, " training dragon " disease, cold syndrome of the stomach.
(11) Cortex Cinnamomi (Tibetan language name: newly wipe): acrid in the mouth, warm in nature.The stomach reinforcing fire dispels the wind, dispersing cold for relieving pain, antidiarrheal.Formula for treating gastropathy, dyspepsia, diarrhoea, hepatopathy, cold " dragon " disease and lung abscess.
(12) Flos Carthami: (Flos Carthami, Tibetan language name: bitter empty): sweet in the mouth, little hardship, cool in nature.Heat clearing away is invigorated blood circulation, nourishing.Cure mainly pneumonia, hepatitis, heat in blood, carbuncle, traumatic injury and gynaecopathia etc.
(13) Rhododendron (Tibetan language name: the Baruch): sweet in the mouth, puckery, property is flat.Heat clearing and inflammation relieving, the kidney invigorating.Cure mainly asthma, edema, physical weakness and water and soil discomfort, dyspepsia, gastroptosis, flatulence.It is strict that skin ulcer is controlled in external.
(14) Semen Granati (Tibetan language name: the plug pearl): sour in the mouth, sweet, digestion back sour in the mouth, warm in nature, profit.Aid digestion, the stomach warming kidney.Cure mainly the inappetence that cold syndrome of the stomach causes, dyspepsia and kidney pain in the lumbar region pain.
(15) Radix Et Rhizoma Rhei (the Tibetan language name: monarch's wood is assorted): sour in the mouth, hardship, digestion back sour in the mouth, cool in nature.Purging heat and dredging bowels, removing pathogenic heat from blood and toxic substance from the body, the clots absorbing eliminate indigestion is invigorated blood circulation.Cure mainly the toxic heating, internal organs heat, food is not changed, abdominal distention, constipation, amenorrhea, liver, gastropathy.
(16) purple Sal Ammoniacus (the Tibetan language name: card is as examining): acrid in the mouth, salty, warm in nature, profit.The stomach warming relieving constipation, relieving distension.Cure mainly the complication of " Baconic " and " dragon ", abdominal distention, borborygmus, food stagnation, constipation.
(17) Flos Caryophylli (the Tibetan language name: the lining is western): acrid in the mouth, hardship, warm in nature.It is cold to dispel the wind, and stomach warming helps digestion, analgesia.Cure mainly cold " dragon " disease, cold syndrome, disorders of meridian, gastropathy, inappetence, the splenopathy, pained, dyspnea.
(18) (adjoin Li Le, Tibetan medicine name: Ba Rula): puckery, digestion is bitter in the mouth afterwards, and is cool in nature for Fructus Terminaliae Billericae.Heat-clearing and toxic substances removing, convergence is nourished blood, and coordinating the actions of various ingredients in a prescription cures mainly " Baconic ", " red crust ", and yellow fluid, diseases such as " dragons ", the spy controls pernicious yellow fluid.
(19) (Tibetan language name: Da Erbu): sour in the mouth, property is flat for Fructus Hippophae extractum.Clearing and antitussive, promoting blood circulation to remove blood stasis, tonifying the lung.Cure mainly cough with copious phlegm, blood stasis amenorrhea, pulmonary tuberculosis, dyspepsia, gastric ulcer.
(20) Fructus Phyllanthi (Tibetan language name: occupy as heat): sweet in the mouth, acid, puckery, cool in nature.Clearing away heat and cooling blood, promoting digestion and invigorating the stomach.Cure mainly hepatopathy, gallbladder disease, dyspepsia, oculopathy and " Baconic ", " red crust " etc. are sick.
(21) Stigma Croci (Tibetan language name: noise made in coughing or vomiting lucky painstaking effort): sweet in the mouth, cool in nature.Blood circulation promoting and blood stasis dispelling, removing pathogenic heat from blood and toxic substance from the body, liver heat removing and eyesight improving is enriched blood, hemostasis.All kinds of hepatopathys of pillar, blood deficiency, menoxenia, the hemorrhage that a variety of causes causes.
(22) Fel Ursi (Tibetan language name: ellipse wood): bitter in the mouth, little sweet, cool in nature.Heat-clearing and toxic substances removing, calmness, pain relieving, function of gallbladder promoting makes eye bright, and is good for the stomach parasite killing.Cure mainly gallbladder-heat, various gallbladder disease such as cholelithiasis, hemorrhage, epilepsy, toothache, corneal nebula, stomachache, skin infection swells and ache, various hepatopathys.
(23) Fructus Tsaoko (Tibetan language name: Ga Gaola): acrid in the mouth, warm in nature.Warming and invigorating the spleen and stomach, aid digestion.Cure mainly " Baconic " disease.Cold syndrome of the stomach, dyspepsia, the food stagnation distension is vomited and diarrhoea phlegm retention.
(24) (Tibetan language name: hot Buddhist nun): sweet in the mouth, puckery, bitter, digestion is sweet in the mouth afterwards, and is warm in nature for Rhizoma Polygonati.Nourishing and fit keeping function, life lengthening, kidney tonifying is mended smart, lung moistening.Cure mainly the edema that cold and heat cause, lose languishment, cough due to consumptive disease in the marrow.
(25) Fructus Tribuli (Tibetan language name: the color fiber crops): sweet in the mouth, puckery, warm in nature.The diuretic damp eliminating.Cure mainly kidney-heat, urine retention, nutritional edema, rheumatic arthritis, stranguria with turbid discharge etc.
(26) (Tibetan language name: Qi Dangga): sweet in the mouth, acid, property is flat for Fructus embeliae laetae.Parasite killing promotes the stomach temperature.Cure mainly taeniasis, edema.
(27) tangut dragonhead (Herba Dracocephali tangutici, Tibetan language name: know the sheep event): sweet in the mouth, hardship, suffering, cold in nature.The heat of clearing gallbladder stomach, hemostasis, yellow fluid reducing.Cure mainly gastric heat, Mental fatigue, dizziness, arthritis and furuncle; Also can tie blood vessel.
(28) Herba Lycopodii (Tibetan language name: rein in folding): sweet in the mouth, hardship, puckery, digestion back sweet in the mouth, cool in nature.Heat clearing away is dispeled the wind.Cure mainly wind heat and do not conform to disease, heat symptom-complex due to " dragon ", " red crust ", " Baconic " three polymerization.Deficiency-heat and goat there is good effect.
The preparation method of Tibetan medicine composite preparation of the present invention, undertaken by following processing step:
Get the raw materials ready → choose → prepare burden → pulverize → mix → decoct → general ball, select ball → drying → polishing → sterilization → packing, the specific requirement of each step is:
A, get the raw materials ready: distinguish the true and false and the quality of medical material, select the high-quality medical material as medicinal raw material.
B, selection: the flavor of 28 in will filling a prescription medical material is removed impurity, foreign body and dis-medicinal part, wherein:
Fructus Hippophae cream is soaked, and boils dissolving, filters, and removes filtering residue, gets filtrate and is concentrated into cream; Fructus Piperis Longi is smashed to pieces; Rhododendron and Fructus Terminaliae Billericae dry; Purple Sal Ammoniacus is broken into fritter; Fructus Hippophae extractum and Fructus Phyllanthi drying; Fel Ursi removes clean epithelium, grinds to form fine powder and uses; Fructus Tsaoko is fried to coke yellow and little heaving, and shells, and gets core, and the time spent smashs to pieces; Rhizoma Polygonati is removed fibrous root, cleans, and puts to scald in the boiling water or steam to the saturating heart, drying.
C, batching: accurately take by weighing medical material except that Fructus Hippophae extractum and Fructus Hippophae cream by the prescription consumption, put into container.
D, pulverizing: the medical material that the C step is prepared adds in the pulverizing mill to be pulverized, and starts grading wheel, crosses 90～100 mesh sieves.
E, mixing: with the medicated powder that the D step crushes, put into Multidimensionblender, mixed 40～50 minutes.
F, decoction: by the prescription consumption, Fructus Hippophae extractum and Fructus Hippophae cream are placed decoction pot, add drinking water 50～70kg, heated and boiled 30 minutes after decoction liquor leaves standstill and cools, is evacuated in all turning barrels after filtration.
G, general ball, select ball: get the medicated powder that the E step mixes and put in the general ball machine, do binding agent, carry out general ball with the decoction liquor that the F step makes; Examine the size of a ball in the general ball process, and constantly weigh, the weight for the treatment of a ball reaches 0.80～0.85g, and moisture is 41.2% o'clock, the pill that will wet places pill-screening machine to select ball, qualified wet pill places pallet, and underproof wet ball then returns and continues general system in the general ball machine, and it is all qualified until wet pill to repeat this process.
H, drying: the pallet that the G step is equipped with wet pill is put into and is pushed drying room on the drying cart, and the control temperature is at 65～75 ℃, dry 7～9 hours, cools then to room temperature and gets pill.
I, polishing: the pill of H step is placed glazing machines, start glazing machines, added 1% the continuous polishing of polishing agent by weight 180 minutes.
Described polishing agent is formulated by 1: 0.1 weight ratio by purified water and crystal sugar.
J, sterilization: the pill of I step is placed drying room, and the control temperature is at 65～75 ℃, and dry heat sterilization 2～3 hours cools then to room temperature and gets the finished product pill.
K, packing: aluminum-plastic packaged, outer package.
Finished product pill of the present invention is rufous, and is lightly seasoned, little hardship.
Usage and consumption: once a day, once two.
Storage method: airtight, moistureproof.
We are about on " diabetes " theoretical basis in the foundation Four-Volume Medical Code, experience in conjunction with more than ten years row medicine accumulation, and modern's diet custom, thereby reasonable cooperation, interaction in the prescription that reaches between each component have science, reasonability and edible safety.
The finished product pill that the present invention makes has better curative effect to diabetes.Have kidney tonifying, diuretic effect.Be used for frequent micturition and sweet, urgent micturition, nephropathy, emaciated physique, spiritlessness and weakness has hypoglycemic activity to the higher person of blood glucose that diabetes cause especially.And this poisonous side effect of medicine is little, and cost is lower, and clinical efficacy is remarkable.
The specific embodiment
Embodiment 1
A kind of Tibetan medicine compositions for the treatment of diabetes is characterized in that it comprises that the component by following weight proportion constitutes:
Fructus Chebulae 6g Fructus Hippophae cream 3g Fructus Piperis Longi 5g natural salt 4g
Trona 6g Radix Aucklandiae 3g Fructus Coriandri sativi 5g Radix Inulae 3g
Fructus Amomi Rotundus 6g Rhizoma Zingiberis 5g Cortex Cinnamomi 3g Flos Carthami 5g
The purple Sal Ammoniacus 1g of Rhododendron 5g Semen Granati 2g Radix Et Rhizoma Rhei 3g
Flos Caryophylli 1g Fructus Terminaliae Billericae 5g Fructus Hippophae extractum 2g Fructus Phyllanthi 3g
Stigma Croci 1g Fel Ursi 1g Fructus Tsaoko 5g Rhizoma Polygonati 5g
Fructus Tribuli 3g Fructus embeliae laetae 6g tangut dragonhead 8g Herba Lycopodii 8g
Described Fructus Hippophae cream be Fructus Hippophae through soaking, boil dissolving, filter, discard filtering residue, filtrate again through concentrating paste.
Described Fructus Hippophae extractum is Fructus Hippophae is concocted gained through routine a paste.
Described Fel Ursi is a made powder behind the clean epithelium.
Embodiment 2
A kind of Tibetan medicine compositions for the treatment of diabetes is characterized in that it comprises that the component by following weight proportion constitutes:
Fructus Chebulae 4.8g Fructus Hippophae cream 3g Fructus Piperis Longi 6g natural salt 3.5g
Trona 7g Radix Aucklandiae 3.6g Fructus Coriandri sativi 4g Radix Inulae 3.6g
Fructus Amomi Rotundus 6g Rhizoma Zingiberis 6g Cortex Cinnamomi 3g Flos Carthami 6g
The purple Sal Ammoniacus 1.2g of Rhododendron 4g Semen Granati 2g Radix Et Rhizoma Rhei 2.4g
Flos Caryophylli 1g Fructus Terminaliae Billericae 4g Fructus Hippophae extractum 2g Fructus Phyllanthi 3.6g
Stigma Croci 1g Fel Ursi 0.8g Fructus Tsaoko 4g Rhizoma Polygonati 5g
Fructus Tribuli 3g Fructus embeliae laetae 7.2g tangut dragonhead 9g Herba Lycopodii 8.5g.
Embodiment 3
The preparation method of Tibetan medicine composite preparation of the present invention, undertaken by following processing step:
A, get the raw materials ready: distinguish the true and false and the quality of medical material, select the high-quality medical material as medicinal raw material.
B, selection: the flavor of 28 in will filling a prescription medical material is removed impurity, foreign body and dis-medicinal part, wherein:
Fructus Hippophae cream is soaked, and boils dissolving, filters, and removes filtering residue, gets filtrate and is concentrated into cream; Fructus Piperis Longi is smashed to pieces; Rhododendron and Fructus Terminaliae Billericae dry; Purple Sal Ammoniacus is broken into fritter; Fructus Hippophae extractum and Fructus Phyllanthi drying; Fel Ursi removes clean epithelium, grinds to form fine powder and uses; Fructus Tsaoko is fried to coke yellow and little heaving, and shells, and gets core, and the time spent smashs to pieces; Rhizoma Polygonati is removed fibrous root, cleans, and puts to scald in the boiling water or steam to the saturating heart, drying.
C, batching: accurately take by weighing medical material except that Fructus Hippophae extractum and Fructus Hippophae cream by the prescription consumption of embodiment 1, put into container.
D, pulverizing: the medical material that the C step is prepared adds in the pulverizing mill to be pulverized, and starts grading wheel, crosses 90～100 mesh sieves.
E, mixing: with the medicated powder that the D step crushes, put into Multidimensionblender, mixed 45 minutes.
F, decoction: by the prescription consumption, Fructus Hippophae extractum and Fructus Hippophae cream are placed decoction pot, add drinking water 60kg, heated and boiled 30 minutes after decoction liquor leaves standstill and cools, is evacuated in all turning barrels after filtration.
G, general ball, select ball: get the medicated powder that the E step mixes and put in the general ball machine, do binding agent, carry out general ball with the decoction liquor that the F step makes; Examine the size of a ball in the general ball process, and constantly weigh, the weight for the treatment of a ball reaches 0.80～0.85g, and moisture is 41.2% o'clock, the pill that will wet places pill-screening machine to select ball, qualified wet pill places pallet, and underproof wet ball then returns and continues general system in the general ball machine, and it is all qualified until wet pill to repeat this process.
H, drying: the pallet that the G step is equipped with wet pill is put into and is pushed drying room on the drying cart, and the control temperature is at 65～75 ℃, dry 7～9 hours, cools then to room temperature and gets pill.
I, polishing: the pill of H step is placed glazing machines, start glazing machines, added 1% the continuous polishing of polishing agent by weight 180 minutes.
Described polishing agent is formulated by 1: 0.1 weight ratio by purified water and crystal sugar;
J, sterilization: the pill of I step is placed drying room, and the control temperature is at 65～75 ℃, and dry heat sterilization 2～3 hours cools then to room temperature and gets the finished product pill.
K, packing: aluminum-plastic packaged, outer package.
Finished product pill of the present invention is rufous, and is lightly seasoned, little hardship.
Usage and consumption: once a day, once two.
Storage method: airtight, moistureproof.
Case 1
Patient Zhao Baoping, the man, 62 years old is coal works, Hai Xiang district, Qinhuangdao, Hebei province.Not taking the preceding state of an illness of this medicine is gouty nephropathy, diabetes.Symptom is tired, weak, weight loss. become thin 8 kilograms, looking into fasting glucose in certain hospital is 7.8mmol/L, post-prandial glycemia 9.0 left and right sides mmol/l.Be diagnosed as type 2 diabetes mellitus.Give insulinize, blood glucose does not have obvious decline.The back blood glucose of leaving hospital is controlled in 10-16mmol/L.The patient merges hyperlipemia, gouty nephropathy.Have a medical check-up: be dispersed in pigmentation spots before the both legs shin.T-CHOL: 6.70mmol/L, carbamide 9.13mmol/L, creatinine 123.7mmol/L, uric acid 447.7mmol/L, glucose 6.73mmol/L.The patient accepted the treatment of this medicine after 3 months, and blood glucose obviously descends, weak remarkable alleviation, triglyceride: 1.23mmol/L, T-CHOL: 5.21mmol/L, glucose in urine feminine gender.So far glucostasis is in 5-7.7mmol/L.
Case 2
Nip patient, the woman, 48 years old is the director of Tibet Shigatse District government.Before not taking this medicine, make a definite diagnosis diabetes, weak, polydipsia, polyuria, visual deterioration are obvious, the finger tip feeling of numbness.Oral administration of metformin, gliclazide, glycemic control is in 8-11mmol/l.Examination in hospital, suggestion insulinize.The treatment of this medicine is accepted in back drug withdrawal, and after four months, glucostasis descends, weak alleviation, and eyesight improving, feeling of numbness does not appear in finger.Monitor blood glucose after the rehabilitation, fasting glucose 4.5-5.4mmol/l, post-prandial glycemia 5.7-8.4mmol/l.
Case 3
Deuterzooid, the man, 57 years old is Tibet Shigatse District people.It is thirsty to take before this medicine the sense of tired back, polydipsia water, polyphagia, become thin, weak, no cardiopalmus, heating etc., do not process.After 4 years, last disease is sent out and is increased the weight of, and visual deterioration.Go to certain hospital to survey more than the fasting glucose 9.0mmol/l, glucose in urine 3-4+ gives metformin and Chinese patent medicine is oral, and blood glucose descends, remission.Occur visual deterioration after half a year, numbness of tongue tip is pointed, is increased the weight of gradually, and edema of pair of lower extremities.In certain hospital's hospitalization, give injection of insulin 34u/ day, add with metformin, glipizide, remission, disconnected afterwards medication 1 year, fasting glucose reaches 11.mmol/l, and hospitalization appears ketoacidosis twice, in the highest 17.0mmol/l.After 8 months, last disease is sent out and is increased the weight of, in the treatment of certain hospital attached to a medical college, insulin injection 48u/ day (12u three before the meal, night, 12u strengthened), and give acarbose, monarch Li Da is oral, glucostasis, remission.Spiritual after being ill not good enough, two is just normal, weight loss.Begin drug withdrawal this year and accept the treatment of this medicine, after 6 months, blood glucose descends steadily, weak alleviation.Edema of lower limbs disappears.The sense of both hands numbness of tongue tip alleviates.Vision is clearly better.Back monitoring blood glucose, fasting glucose 5.4-7.3mmol/l, post-prandial glycemia 6.4-7.9mmol/l.
Claims (8)
1. Tibetan medicine compositions for the treatment of diabetes is characterized in that its crude drug is formed to count by weight ratio:
Fructus Chebulae 4.8～7.2g Fructus Hippophae cream 2.4～3.6g Fructus Piperis Longi 4～6g natural salt 3.2～4.8g
Trona 4.8～7.2g Radix Aucklandiae 2.4～3.6g Fructus Coriandri sativi 4～6g Radix Inulae 2.4～3.6g
Fructus Amomi Rotundus 4.8～7.2g Rhizoma Zingiberis 4～6g Cortex Cinnamomi 2.4～3.6g Flos Carthami 4～6g
The purple Sal Ammoniacus 0.8～1.2g of Rhododendron 4～6g Semen Granati 1.6～2.4g Radix Et Rhizoma Rhei 2.4～3.6g
Flos Caryophylli 0.8～1.2g Fructus Terminaliae Billericae 4～6g Fructus Hippophae extractum 1.6～2.4g Fructus Phyllanthi 2.4～3.6g
Stigma Croci 0.8～1.2g Fel Ursi 0.8～1.2g Fructus Tsaoko 4～6g Rhizoma Polygonati 4～6g
Fructus Tribuli 2.4～3.6g Fructus embeliae laetae 4.8～7.2g tangut dragonhead 7.4～9.6g Herba Lycopodii 7.4～9.6g.
2. treat the Tibetan medicine compositions of diabetes according to claim 1, it is characterized in that its crude drug is formed to count by weight ratio:
Fructus Chebulae 4.8g Fructus Hippophae cream 3g Fructus Piperis Longi 6g natural salt 3.5g
Trona 7g Radix Aucklandiae 3.6g Fructus Coriandri sativi 4g Radix Inulae 3.6g
Fructus Amomi Rotundus 6g Rhizoma Zingiberis 6g Cortex Cinnamomi 3g Flos Carthami 6g
The purple Sal Ammoniacus 1.2g of Rhododendron 4g Semen Granati 2g Radix Et Rhizoma Rhei 2.4g
Flos Caryophylli 1g Fructus Terminaliae Billericae 4g Fructus Hippophae extractum 2g Fructus Phyllanthi 3.6g
Stigma Croci 1g Fel Ursi 0.8g Fructus Tsaoko 4g Rhizoma Polygonati 5g
Fructus Tribuli 3g Fructus embeliae laetae 7.2g tangut dragonhead 9g Herba Lycopodii 8.5g.
3. treat the Tibetan medicine compositions of diabetes as claimed in claim 1 or 2, it is characterized in that described Fructus Hippophae cream be Fructus Hippophae through soaking, boil dissolving, filter, discard filtering residue, filtrate again through concentrating paste.
4. treat the Tibetan medicine compositions of diabetes as claimed in claim 1 or 2, it is characterized in that described Fructus Hippophae extractum is Fructus Hippophae is concocted gained through routine a paste.
5. treat the Tibetan medicine compositions of diabetes as claimed in claim 1 or 2, it is characterized in that described Fel Ursi is a made powder behind the clean epithelium.
6. treat the preparation method of the Tibetan medicine composite preparation of diabetes according to claim 1, it is characterized in that being undertaken by following processing step:
A, get the raw materials ready: distinguish the true and false and the quality of medical material, select the high-quality medical material as medicinal raw material;
B, selection: the flavor of 28 in will filling a prescription medical material is removed impurity, foreign body and dis-medicinal part, wherein:
Fructus Hippophae cream is soaked, and boils dissolving, filters, and removes filtering residue, gets filtrate and is concentrated into cream; Fructus Piperis Longi is smashed to pieces; Rhododendron and Fructus Terminaliae Billericae dry; Purple Sal Ammoniacus is broken into fritter; Fructus Hippophae extractum and Fructus Phyllanthi drying; Fel Ursi removes clean epithelium, grinds to form fine powder and uses; Fructus Tsaoko is fried to coke yellow and little heaving, and shells, and gets core, and the time spent smashs to pieces; Rhizoma Polygonati is removed fibrous root, cleans, and puts to scald in the boiling water or steam to the saturating heart, drying;
C, batching: accurately take by weighing medical material except that Fructus Hippophae extractum and Fructus Hippophae cream by the prescription consumption, put into container;
D, pulverizing: the medical material that the C step is prepared adds in the pulverizing mill to be pulverized, and starts grading wheel, crosses 90～100 mesh sieves;
E, mixing: with the medicated powder that the D step crushes, put into Multidimensionblender, mixed 40～50 minutes;
F, decoction: by the prescription consumption, Fructus Hippophae extractum and Fructus Hippophae cream are placed decoction pot, add drinking water 50～70kg, heated and boiled 30 minutes after decoction liquor leaves standstill and cools, is evacuated in all turning barrels after filtration;
G, general ball, select ball: get the medicated powder that the E step mixes and put in the general ball machine, do binding agent with the decoction liquor that the F step makes, carry out general ball, the weight for the treatment of a ball reaches 0.80～0.85g, and moisture is 41.2% o'clock, and the pill that will wet places pill-screening machine to select ball, and qualified wet pill places pallet, underproof wet ball then returns and continues general system in the general ball machine, and it is all qualified until wet pill to repeat this process;
H, drying: the pallet that the G step is equipped with wet pill is put into and is pushed drying room on the drying cart, and the control temperature is at 65～75 ℃, dry 7～9 hours, cools then to room temperature and gets pill;
I, polishing: the pill of H step is placed glazing machines, start glazing machines, added 1% the continuous polishing of polishing agent by weight 180 minutes;
J, sterilization: the pill of I step is placed drying room, and the control temperature is at 65～75 ℃, and dry heat sterilization 2～3 hours cools then to room temperature and gets the finished product pill;
K, packing: aluminum-plastic packaged, outer package.
7. as the preparation method of the Tibetan medicine composite preparation of treatment diabetes as described in the claim 6, it is characterized in that this Tibetan medicine composite preparation is a pill.
8. as the Tibetan medicine preparation of compositions method of treatment diabetes as described in the claim 6, it is characterized in that the polishing agent that adds in the step is formulated by 1: 0.1 weight ratio by purified water and crystal sugar.
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| CN102366596B (en) * | 2011-09-28 | 2013-06-05 | 久美彭措 | Medicine for treating diabetes and preparation method thereof |
| CN102366443B (en) * | 2011-09-28 | 2013-08-07 | 久美彭措 | Medicine for treating diabetes and preparation method thereof |
| CN102366480B (en) * | 2011-09-28 | 2013-05-08 | 久美彭措 | Medicine for treating diabetes and preparation method thereof |
| CN102366595B (en) * | 2011-09-28 | 2013-07-10 | 久美彭措 | Medicine for treating diabetes and preparation method thereof |
| CN102366540B (en) * | 2011-09-28 | 2013-06-05 | 久美彭措 | Medicine for treating diabetes and its preparation method |
| CN102716197A (en) * | 2012-07-12 | 2012-10-10 | 措尼 | Tibetan medicine for treating constipation and preparation method thereof |
| CN103736071B (en) * | 2014-01-23 | 2016-05-11 | 西藏金哈达药业有限公司 | A kind of composition with auxiliary hyperglycemic effect and application thereof, preparation method |
| CN103961392B (en) * | 2014-05-25 | 2017-02-01 | 青海省通天河藏药制药有限责任公司 | Traditional Tibetan medicine for treating diabetes |
| CN103948666B (en) * | 2014-05-25 | 2017-02-01 | 青海省通天河藏药制药有限责任公司 | Preparation method of Tibetan medicine for treating diabetes |
| CN105477102A (en) * | 2015-12-18 | 2016-04-13 | 吴福 | Traditional Chinese medicine for treating type 2 diabetes |
| CN109771616A (en) * | 2017-06-16 | 2019-05-21 | 包国方 | A kind of Pediluvium medicament and preparation method thereof for treating diabetes |
| CN110201054B (en) * | 2019-06-22 | 2021-12-07 | 锡林郭勒盟蒙医医院 | Mongolian medicine composition for treating thyroid diseases and preparation method of pills thereof |
| CN113143987A (en) * | 2021-06-05 | 2021-07-23 | 常州禾春医药科技有限公司 | Traditional Chinese medicine composition for preventing and treating pulmonary hypertension and application thereof |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1954879A (en) * | 2005-10-26 | 2007-05-02 | 西乌珠穆沁旗蒙医医院 | Granule of zhamusa-four-does and its preparation method |
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| CN1954879A (en) * | 2005-10-26 | 2007-05-02 | 西乌珠穆沁旗蒙医医院 | Granule of zhamusa-four-does and its preparation method |
Non-Patent Citations (2)
| Title |
|---|
| 张涓等.《藏药降糖舒胶囊降血糖作用的实验研究》.《贵阳中医学院学报》.2008,第30卷(第4期),67-58. * |
| 朗杰卓嘎.《糖尿病与藏药》.《西藏研究》.2007,(第1期),107-109. * |
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