CN101693896B - 醛脱氢酶基因 - Google Patents

醛脱氢酶基因 Download PDF

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Publication number
CN101693896B
CN101693896B CN2009101755968A CN200910175596A CN101693896B CN 101693896 B CN101693896 B CN 101693896B CN 2009101755968 A CN2009101755968 A CN 2009101755968A CN 200910175596 A CN200910175596 A CN 200910175596A CN 101693896 B CN101693896 B CN 101693896B
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CN101693896A (zh
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星野达雄
宮崎太郎
杉泽辉秀
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DSM IP Assets BV
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0006—Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C12P7/58—Aldonic, ketoaldonic or saccharic acids
    • C12P7/60—2-Ketogulonic acid

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  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
CN2009101755968A 2002-09-27 2003-09-22 醛脱氢酶基因 Expired - Fee Related CN101693896B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP02021650 2002-09-27
EA02021650.3 2002-09-27
EP02021650.3 2002-09-27

Related Parent Applications (1)

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CNB038231956A Division CN100558886C (zh) 2002-09-27 2003-09-22 醛脱氢酶基因

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CN101693896A CN101693896A (zh) 2010-04-14
CN101693896B true CN101693896B (zh) 2012-07-11

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CNB038231956A Expired - Fee Related CN100558886C (zh) 2002-09-27 2003-09-22 醛脱氢酶基因

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US (1) US7135315B2 (https=)
EP (1) EP1543114B1 (https=)
JP (1) JP4528624B2 (https=)
KR (1) KR101070110B1 (https=)
CN (2) CN101693896B (https=)
AT (1) ATE404664T1 (https=)
AU (1) AU2003299104A1 (https=)
DE (1) DE60322921D1 (https=)
WO (1) WO2004029235A2 (https=)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005017172A1 (en) * 2003-08-14 2005-02-24 Dsm Ip Assets B.V. Microbial production of l-ascorbic acid
US9279138B2 (en) * 2005-02-11 2016-03-08 Dsm Assets B.V. Vitamin C production in a microorganism, gluconobacter
WO2006084725A1 (en) * 2005-02-11 2006-08-17 Dsm Ip Assets B.V. Novel gene sts 16
WO2006084647A1 (en) * 2005-02-11 2006-08-17 Dsm Ip Assets B.V. Gene vcs 01
WO2006084720A2 (en) * 2005-02-11 2006-08-17 Dsm Ip Assets B.V. Hpr kinase from gluconobacter oxydan
CN101316929A (zh) 2005-09-08 2008-12-03 帝斯曼知识产权资产管理有限公司 新颖的基因sms 37
EP1931785A2 (en) 2005-09-09 2008-06-18 DSMIP Assets B.V. Novel gene gms 01
LT2821494T (lt) 2007-03-16 2017-04-25 Genomatica, Inc. 1,4-butandiolio ir jo pirmtakų biosintezės būdai ir kompozicijos
US7947483B2 (en) 2007-08-10 2011-05-24 Genomatica, Inc. Methods and organisms for the growth-coupled production of 1,4-butanediol
US7858350B2 (en) 2008-09-10 2010-12-28 Genomatica, Inc. Microorganisms for the production of 1,4-butanediol
SI3199511T1 (sl) 2009-06-04 2020-07-31 Genomatica, Inc. Proces separacije komponent fermentacijske brozge
WO2010141920A2 (en) 2009-06-04 2010-12-09 Genomatica, Inc. Microorganisms for the production of 1,4-butanediol and related methods
CN101649323B (zh) * 2009-06-16 2011-06-22 武汉工程大学 按毕赤酵母偏爱密码子设计人乙醛脱氢酶2序列的方法
US8377666B2 (en) 2009-10-13 2013-02-19 Genomatica, Inc. Microorganisms for the production of 1,4-butanediol, 4-hydroxybutanal, 4-hydroxybutyryl-coa, putrescine and related compounds, and methods related thereto
US8530210B2 (en) 2009-11-25 2013-09-10 Genomatica, Inc. Microorganisms and methods for the coproduction 1,4-butanediol and gamma-butyrolactone
US8637286B2 (en) 2010-02-23 2014-01-28 Genomatica, Inc. Methods for increasing product yields
US8048661B2 (en) 2010-02-23 2011-11-01 Genomatica, Inc. Microbial organisms comprising exogenous nucleic acids encoding reductive TCA pathway enzymes
CN102492762A (zh) * 2011-12-09 2012-06-13 天津大学 含有编码山梨酮脱氢酶基因载体的氧化葡糖杆菌的用途
WO2013184602A2 (en) 2012-06-04 2013-12-12 Genomatica, Inc. Microorganisms and methods for production of 4-hydroxybutyrate, 1,4-butanediol and related compounds
EP3856896A1 (en) * 2018-09-26 2021-08-04 Genomatica, Inc. Aldehyde dehydrogenase variants and methods of using same
CN111321153B (zh) * 2020-04-26 2021-08-17 广西大学 一种来源于玉米的黑暗响应gd2基因及其应用
KR102460589B1 (ko) 2021-02-17 2022-10-28 주식회사 피코엔텍 글루타치온과 알데히드탈수소효소를 함유하는 숙취해소제
CN115948430B (zh) * 2022-05-26 2024-06-14 南京农业大学 梨醛脱氢酶PusALDH1及其编码基因和应用

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5437989A (en) * 1992-12-30 1995-08-01 Hoffmann-La Roche Inc. Alcohol/aldehyde dehydrogenase from Gluconobacter oxydans DSM 4025 FERM BP-3812
CN1171441A (zh) * 1996-02-19 1998-01-28 弗·哈夫曼-拉罗切有限公司 一种醛脱氢酶

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0373181B1 (en) * 1988-01-14 1995-11-08 F. Hoffmann-La Roche Ag Novel coenzyme independent l-sorbosone dehydrogenase
DE69821326T2 (de) * 1997-12-01 2004-11-18 Dsm Ip Assets B.V. Aldehyd-Dehydrogenase
CN1351665A (zh) * 1999-03-17 2002-05-29 藤泽药品工业株式会社 山梨糖醇脱氢酶、其编码基因及它们的用途
JP2002125689A (ja) 2000-10-25 2002-05-08 Koji Hayade 融合蛋白質
EP1332216B1 (en) 2000-10-27 2011-08-17 Roche Diagnostics GmbH Variants of soluble pyrroloquinoline quinone-dependent glucose dehydrogenase

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5437989A (en) * 1992-12-30 1995-08-01 Hoffmann-La Roche Inc. Alcohol/aldehyde dehydrogenase from Gluconobacter oxydans DSM 4025 FERM BP-3812
CN1171441A (zh) * 1996-02-19 1998-01-28 弗·哈夫曼-拉罗切有限公司 一种醛脱氢酶

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
Akira Asakura and Tatsuo Hoshino,.Isolation and characterization of a new quinoprotein dehydrogenase..《Biosci. Biotechnol. Biochem.》.1999,第63卷(第1期),46-53. *

Also Published As

Publication number Publication date
EP1543114B1 (en) 2008-08-13
CN1688689A (zh) 2005-10-26
KR20050052664A (ko) 2005-06-03
US20060127994A1 (en) 2006-06-15
US7135315B2 (en) 2006-11-14
JP2006500052A (ja) 2006-01-05
CN101693896A (zh) 2010-04-14
JP4528624B2 (ja) 2010-08-18
EP1543114A2 (en) 2005-06-22
AU2003299104A8 (en) 2004-04-19
ATE404664T1 (de) 2008-08-15
AU2003299104A1 (en) 2004-04-19
CN100558886C (zh) 2009-11-11
WO2004029235A3 (en) 2004-07-08
WO2004029235A2 (en) 2004-04-08
DE60322921D1 (de) 2008-09-25
KR101070110B1 (ko) 2011-10-05

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