CN101688240A - 通过微rna预测癌症患者的治疗后存活预期 - Google Patents

通过微rna预测癌症患者的治疗后存活预期 Download PDF

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CN101688240A
CN101688240A CN200880011562A CN200880011562A CN101688240A CN 101688240 A CN101688240 A CN 101688240A CN 200880011562 A CN200880011562 A CN 200880011562A CN 200880011562 A CN200880011562 A CN 200880011562A CN 101688240 A CN101688240 A CN 101688240A
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hsa
expression level
survival
expection
mir221
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陈健尉
俞松良
陈璇宇
张基晟
陈志毅
杨泮池
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National Taiwan University NTU
DCB USA LLC
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DCB USA LLC
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    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
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    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
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    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/178—Oligonucleotides characterized by their use miRNA, siRNA or ncRNA

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CN200880011562A 2007-04-10 2008-04-09 通过微rna预测癌症患者的治疗后存活预期 Pending CN101688240A (zh)

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US91099307P 2007-04-10 2007-04-10
US60/910,993 2007-04-10
PCT/US2008/059767 WO2008124777A1 (en) 2007-04-10 2008-04-09 Predicting post-treatment survival in cancer patients with micrornas

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US (1) US7745134B2 (enExample)
EP (1) EP2134874A4 (enExample)
JP (1) JP2010523156A (enExample)
KR (1) KR20100027102A (enExample)
CN (1) CN101688240A (enExample)
AU (1) AU2008237036A1 (enExample)
CA (1) CA2695868A1 (enExample)
CO (1) CO6231056A2 (enExample)
IL (1) IL201298A0 (enExample)
MX (1) MX2009010899A (enExample)
RU (1) RU2009141359A (enExample)
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CN108363907A (zh) * 2018-05-09 2018-08-03 中国科学院昆明动物研究所 一种基于多基因表达特征谱的肺腺癌个性化预后评估方法
CN108470111A (zh) * 2018-05-09 2018-08-31 中国科学院昆明动物研究所 一种基于多基因表达特征谱的胃癌个性化预后评估方法
CN108611416A (zh) * 2018-05-09 2018-10-02 中国科学院昆明动物研究所 一种基于多基因表达特征谱的宫颈癌个性化预后评估方法
CN108630317A (zh) * 2018-05-09 2018-10-09 中国科学院昆明动物研究所 一种基于多基因表达特征谱的肝癌个性化预后评估方法
CN108647493A (zh) * 2018-05-09 2018-10-12 中国科学院昆明动物研究所 一种基于多基因表达特征谱的肾透明细胞癌个性化预后评估方法
CN108648826A (zh) * 2018-05-09 2018-10-12 中国科学院昆明动物研究所 一种基于多基因表达特征谱的胰腺癌个性化预后评估方法
CN108733980A (zh) * 2018-05-09 2018-11-02 中国科学院昆明动物研究所 一种基于多基因表达特征谱的胶质母细胞瘤个性化预后评估方法
CN111172285A (zh) * 2020-02-26 2020-05-19 江南大学附属医院 用于胰腺癌早期诊断和/或预后监测的miRNA组及其应用
CN111354421A (zh) * 2018-12-24 2020-06-30 奎克生技光电股份有限公司 健康风险评估方法

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CN103028120B (zh) 2005-09-12 2015-08-12 俄亥俄州立大学研究基金会 用于诊断或治疗bcl2相关癌症的组合物和方法
WO2007081720A2 (en) 2006-01-05 2007-07-19 The Ohio State University Research Foundation Microrna-based methods and compositions for the diagnosis, prognosis and treatment of lung cancer
ES2524018T3 (es) 2006-01-05 2014-12-03 The Ohio State University Research Foundation Anomalías de la expresión de microARN en tumores pancreáticos endocrinos y acinares
EP2487260B1 (en) 2006-01-05 2015-07-08 The Ohio State University Research Foundation Microrna-based methods and compositions for the diagnosis and treatment of solid cancers
EP2369012A1 (en) 2006-03-20 2011-09-28 The Ohio State University Research Foundation Micro-RNA fingerprints during human megakaryocytopoiesis
CA2657030A1 (en) 2006-07-13 2008-01-17 The Ohio State University Research Foundation, An Instrumentality Of The State Of Ohio Micro-rna-based methods and compositions for the diagnosis and treatment of colon cancer-related diseases
US8071292B2 (en) 2006-09-19 2011-12-06 The Ohio State University Research Foundation Leukemia diagnostic methods
JP5501766B2 (ja) 2006-11-01 2014-05-28 ジ・オハイオ・ステイト・ユニバーシティ・リサーチ・ファウンデイション 肝細胞癌における生存および転移を予測するためのマイクロｒｎａ発現サイン
US8034560B2 (en) 2007-01-31 2011-10-11 The Ohio State University Research Foundation MicroRNA-based methods and compositions for the diagnosis, prognosis and treatment of acute myeloid leukemia (AML)
CA2690144A1 (en) * 2007-06-08 2008-12-18 The Government Of The United States Of America As Represented By The Sec Retary Of Department Of Health And Human Services Methods for determining hepatocellular carcinoma subtype and detecting hepatic cancer stem cells
US8053186B2 (en) 2007-06-15 2011-11-08 The Ohio State University Research Foundation Oncogenic ALL-1 fusion proteins for targeting Drosha-mediated microRNA processing
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AU2008283997B2 (en) 2007-08-03 2014-04-10 The Ohio State University Research Foundation Ultraconserved regions encoding ncRNAs
CN101836112A (zh) 2007-08-22 2010-09-15 俄亥俄州立大学研究基金会 用于在人急性白血病中诱导epha7和erk磷酸化的脱调节的方法和组合物
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WO2010054386A2 (en) * 2008-11-10 2010-05-14 Battelle Memorial Institute Methods, compositions, and devices utilizing microrna to determine physiological conditions
US8729041B2 (en) 2008-12-03 2014-05-20 The Johns Hopkins University Compositions and methods for treating hepatic neoplasia
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CN101638656B (zh) * 2009-08-28 2011-05-11 南京医科大学 一种与非小细胞肺癌预后相关的血清/血浆miRNA标志物及其应用
JP5960060B2 (ja) 2009-11-23 2016-08-02 ジ・オハイオ・ステート・ユニバーシティ 腫瘍細胞の増殖、遊走および浸潤に影響を与えるために有用な物質および方法
JP5763098B2 (ja) * 2009-12-20 2015-08-12 アスチュート メディカル，インコーポレイテッド 腎損傷および腎不全の診断および予後診断のための方法ならびに組成物
US20110223607A1 (en) 2010-03-12 2011-09-15 Quest Diagnostics Investments Incorporated Circulating microrna as a marker for hepatocellular carcinoma
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US8664192B2 (en) 2011-03-07 2014-03-04 The Ohio State University Mutator activity induced by microRNA-155 (miR-155) links inflammation and cancer
US8404437B2 (en) 2011-03-29 2013-03-26 Taipei Veterans General Hospital MicroRNA as a cancer progression predictor and its use for treating cancer
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CN108470111B (zh) * 2018-05-09 2022-01-18 中国科学院昆明动物研究所 一种基于多基因表达特征谱的胃癌个性化预后评估方法
CN108611416B (zh) * 2018-05-09 2020-12-29 中国科学院昆明动物研究所 一种基于多基因表达特征谱的宫颈癌个性化预后评估方法
CN108470111A (zh) * 2018-05-09 2018-08-31 中国科学院昆明动物研究所 一种基于多基因表达特征谱的胃癌个性化预后评估方法
CN108611416A (zh) * 2018-05-09 2018-10-02 中国科学院昆明动物研究所 一种基于多基因表达特征谱的宫颈癌个性化预后评估方法
CN108630317A (zh) * 2018-05-09 2018-10-09 中国科学院昆明动物研究所 一种基于多基因表达特征谱的肝癌个性化预后评估方法
CN108647493A (zh) * 2018-05-09 2018-10-12 中国科学院昆明动物研究所 一种基于多基因表达特征谱的肾透明细胞癌个性化预后评估方法
CN108648826A (zh) * 2018-05-09 2018-10-12 中国科学院昆明动物研究所 一种基于多基因表达特征谱的胰腺癌个性化预后评估方法
CN108733980A (zh) * 2018-05-09 2018-11-02 中国科学院昆明动物研究所 一种基于多基因表达特征谱的胶质母细胞瘤个性化预后评估方法
CN108363907A (zh) * 2018-05-09 2018-08-03 中国科学院昆明动物研究所 一种基于多基因表达特征谱的肺腺癌个性化预后评估方法
CN108630317B (zh) * 2018-05-09 2022-04-15 中国科学院昆明动物研究所 一种基于多基因表达特征谱的肝癌个性化预后评估方法
CN108648826B (zh) * 2018-05-09 2022-04-15 中国科学院昆明动物研究所 一种基于多基因表达特征谱的胰腺癌个性化预后评估方法
CN108647493B (zh) * 2018-05-09 2022-01-18 中国科学院昆明动物研究所 一种肾透明细胞癌个性化预后评估方法
CN108320806A (zh) * 2018-05-09 2018-07-24 中国科学院昆明动物研究所 一种基于多基因表达特征谱的结肠癌个性化预后评估方法
CN108733980B (zh) * 2018-05-09 2022-01-18 中国科学院昆明动物研究所 基于多基因表达特征谱胶质母细胞瘤个性化预后评估方法
CN108363907B (zh) * 2018-05-09 2022-01-18 中国科学院昆明动物研究所 一种基于多基因表达特征谱的肺腺癌个性化预后评估方法
CN108320806B (zh) * 2018-05-09 2022-04-12 中国科学院昆明动物研究所 一种基于多基因表达特征谱的结肠癌个性化预后评估方法
CN111354421A (zh) * 2018-12-24 2020-06-30 奎克生技光电股份有限公司 健康风险评估方法
CN111172285A (zh) * 2020-02-26 2020-05-19 江南大学附属医院 用于胰腺癌早期诊断和/或预后监测的miRNA组及其应用

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US7745134B2 (en) 2010-06-29
AU2008237036A2 (en) 2010-09-09
WO2008124777A1 (en) 2008-10-16
IL201298A0 (en) 2010-05-31
KR20100027102A (ko) 2010-03-10
AU2008237036A1 (en) 2008-10-16
EP2134874A1 (en) 2009-12-23
TWI367949B (en) 2012-07-11
EP2134874A4 (en) 2010-12-22
TW200912002A (en) 2009-03-16
RU2009141359A (ru) 2011-05-20
MX2009010899A (es) 2010-02-17
JP2010523156A (ja) 2010-07-15
CO6231056A2 (es) 2010-12-20
CA2695868A1 (en) 2008-10-16

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