MX2009010899A - Prediccion de la supervivencia al post-tratamiento en pacientes de cancer con micro-rnas. - Google Patents
Prediccion de la supervivencia al post-tratamiento en pacientes de cancer con micro-rnas.Info
- Publication number
- MX2009010899A MX2009010899A MX2009010899A MX2009010899A MX2009010899A MX 2009010899 A MX2009010899 A MX 2009010899A MX 2009010899 A MX2009010899 A MX 2009010899A MX 2009010899 A MX2009010899 A MX 2009010899A MX 2009010899 A MX2009010899 A MX 2009010899A
- Authority
- MX
- Mexico
- Prior art keywords
- micrornas
- cancer patients
- hsa
- treatment survival
- predicting post
- Prior art date
Links
- 206010028980 Neoplasm Diseases 0.000 title abstract 3
- 201000011510 cancer Diseases 0.000 title abstract 3
- 230000004083 survival effect Effects 0.000 title abstract 2
- 108091070501 miRNA Proteins 0.000 title 1
- 108091068985 Homo sapiens miR-137 stem-loop Proteins 0.000 abstract 1
- 108091067627 Homo sapiens miR-182 stem-loop Proteins 0.000 abstract 1
- 108091067572 Homo sapiens miR-221 stem-loop Proteins 0.000 abstract 1
- 108091067570 Homo sapiens miR-372 stem-loop Proteins 0.000 abstract 1
- 108700011259 MicroRNAs Proteins 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/118—Prognosis of disease development
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/178—Oligonucleotides characterized by their use miRNA, siRNA or ncRNA
Abstract
La invención proporciona un método para predecir la perspectiva de supervivencia pos-tratamiento de un paciente de cáncer basado en el(los) nivel(es) de expresión de microRNAs hsa-miR137, hsa-miR372, hsa-miR182*, hsa-miR221, y hsa-let-7a en ese paciente de cáncer.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US91099307P | 2007-04-10 | 2007-04-10 | |
PCT/US2008/059767 WO2008124777A1 (en) | 2007-04-10 | 2008-04-09 | Predicting post-treatment survival in cancer patients with micrornas |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2009010899A true MX2009010899A (es) | 2010-02-17 |
Family
ID=39831416
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2009010899A MX2009010899A (es) | 2007-04-10 | 2008-04-09 | Prediccion de la supervivencia al post-tratamiento en pacientes de cancer con micro-rnas. |
Country Status (13)
Country | Link |
---|---|
US (1) | US7745134B2 (es) |
EP (1) | EP2134874A4 (es) |
JP (1) | JP2010523156A (es) |
KR (1) | KR20100027102A (es) |
CN (1) | CN101688240A (es) |
AU (1) | AU2008237036A1 (es) |
CA (1) | CA2695868A1 (es) |
CO (1) | CO6231056A2 (es) |
IL (1) | IL201298A0 (es) |
MX (1) | MX2009010899A (es) |
RU (1) | RU2009141359A (es) |
TW (1) | TWI367949B (es) |
WO (1) | WO2008124777A1 (es) |
Families Citing this family (49)
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CN103882124B (zh) | 2005-08-01 | 2015-11-18 | 俄亥俄州立大学研究基金会 | 用于乳腺癌的诊断、预后和治疗的基于MicroRNA的方法和组合物 |
AU2006291165B2 (en) | 2005-09-12 | 2013-03-14 | The Ohio State University Research Foundation | Compositions and methods for the diagnosis and therapy of BCL2-associated cancers |
EP2591794A1 (en) | 2006-01-05 | 2013-05-15 | The Ohio State University Research Foundation | MicroRNA expressions abnormalities in pancreatic endocrine and acinar tumors |
CA2633754C (en) | 2006-01-05 | 2013-06-18 | The Ohio State University Research Foundation | Microrna-based methods and compositions for the diagnosis and treatment of solid cancers |
WO2007081720A2 (en) | 2006-01-05 | 2007-07-19 | The Ohio State University Research Foundation | Microrna-based methods and compositions for the diagnosis, prognosis and treatment of lung cancer |
EP2371971B1 (en) | 2006-03-20 | 2013-11-27 | The Ohio State University Research Foundation | Microrna fingerprints during human megakaryocytopoiesis |
EP2455493B1 (en) | 2006-07-13 | 2014-01-08 | The Ohio State University Research Foundation | Micro-RNA-based methods and compositions for the diagnosis and treatment of colon related diseases |
EP2061907B1 (en) | 2006-09-19 | 2011-11-23 | The Ohio State University Research Foundation | Tcl1 expression in chronic lymphocytic leukemia (cll) regulated by mir-29 and mir-181 |
WO2008054828A2 (en) | 2006-11-01 | 2008-05-08 | The Ohio State University Research Foundation | Microrna expression signature for predicting survival and metastases in hepatocellular carcinoma |
CN103555825B (zh) | 2007-01-31 | 2015-09-30 | 俄亥俄州立大学研究基金会 | 用于急性髓细胞白血病(aml)的诊断、预后和治疗的基于微rna的方法和组合物 |
US8465917B2 (en) | 2007-06-08 | 2013-06-18 | The Ohio State University Research Foundation | Methods for determining heptocellular carcinoma subtype and detecting hepatic cancer stem cells |
CN101918424A (zh) | 2007-06-15 | 2010-12-15 | 俄亥俄州立大学研究基金会 | 用于靶向由Drosha介导的微小RNA加工的致癌ALL-1融合蛋白 |
US8367632B2 (en) | 2007-07-31 | 2013-02-05 | Ohio State University Research Foundation | Methods for reverting methylation by targeting methyltransferases |
EP2173908B1 (en) | 2007-08-03 | 2016-01-06 | The Ohio State University Research Foundation | Ultraconserved regions encoding ncrnas |
WO2009026487A1 (en) | 2007-08-22 | 2009-02-26 | The Ohio State University Research Foundation | Methods and compositions for inducing deregulation of epha7 and erk phosphorylation in human acute leukemias |
CN103898069A (zh) | 2007-10-26 | 2014-07-02 | 俄亥俄州立大学研究基金会 | 鉴定脆性组氨酸三联体(Fhit)相互作用的方法及其用途 |
CN102149827B (zh) | 2008-06-11 | 2014-08-20 | 由卫生与公众服务部代表的美利坚合众国政府 | MiR-26家族作为肝细胞癌和对治疗的应答性的预测性标志物的用途 |
EP2364367B8 (en) * | 2008-11-10 | 2017-08-23 | Battelle Memorial Institute | Method utilizing microrna for detecting interstitial lung disease |
WO2010065630A2 (en) * | 2008-12-03 | 2010-06-10 | The Johns Hopkins University | Compositions and methods for treating hepatic neoplasia |
EP2196543A1 (en) * | 2008-12-15 | 2010-06-16 | Koninklijke Philips Electronics N.V. | Compositions and methods for micro-rna expression profiling of hepatocellular cancer |
CN102272330B (zh) * | 2009-02-23 | 2014-04-23 | 博奥生物有限公司 | 用于肺癌诊断、预后和提高生存率的试剂盒 |
CN101638656B (zh) * | 2009-08-28 | 2011-05-11 | 南京医科大学 | 一种与非小细胞肺癌预后相关的血清/血浆miRNA标志物及其应用 |
US8916533B2 (en) | 2009-11-23 | 2014-12-23 | The Ohio State University | Materials and methods useful for affecting tumor cell growth, migration and invasion |
MX342967B (es) * | 2009-12-20 | 2016-10-19 | Astute Medical Inc | Metodos y composiciones para la diagnosis y prognosis de lesion renal y falla renal. |
US20110223607A1 (en) * | 2010-03-12 | 2011-09-15 | Quest Diagnostics Investments Incorporated | Circulating microrna as a marker for hepatocellular carcinoma |
WO2012065049A1 (en) | 2010-11-12 | 2012-05-18 | The Ohio State University Research Foundation | Materials and methods related to microrna-21, mismatch repair, and colorectal cancer |
CN103313706A (zh) | 2010-11-15 | 2013-09-18 | 俄亥俄州立大学研究基金会 | 控制释放粘膜粘合系统 |
EP2683387A4 (en) | 2011-03-07 | 2014-09-03 | Univ Ohio State | MUTATORY ACTIVITY INDUCED BY INFLAMMATION OF MICROARN-155 (MIR-155) BINDING AND CANCER |
US8404437B2 (en) | 2011-03-29 | 2013-03-26 | Taipei Veterans General Hospital | MicroRNA as a cancer progression predictor and its use for treating cancer |
WO2012151212A1 (en) * | 2011-05-01 | 2012-11-08 | University Of Rochester | Multifocal hepatocellular carcinoma microrna expression patterns and uses thereof |
CN103857796A (zh) | 2011-09-16 | 2014-06-11 | Lsip基金运营联合公司 | 膀胱癌细胞的检测方法、用于膀胱癌细胞的检测方法的引物及膀胱癌标记物 |
EP2766500A4 (en) | 2011-10-14 | 2015-10-14 | Univ Ohio State | METHODS AND MATERIALS RELATED TO OVARIAN CANCER |
US9481885B2 (en) | 2011-12-13 | 2016-11-01 | Ohio State Innovation Foundation | Methods and compositions related to miR-21 and miR-29a, exosome inhibition, and cancer metastasis |
EP2800820B1 (en) * | 2011-12-19 | 2020-04-08 | Valley Health System | Methods and kits for detecting subjects having pancreatic cancer |
EP2804960A4 (en) | 2012-01-20 | 2015-08-19 | Univ Ohio State | BREAST CANCER BIOMARK SIGNATURES FOR INVASIVITY AND FORECAST |
US8846316B2 (en) | 2012-04-30 | 2014-09-30 | Industrial Technology Research Institute | Biomarker for human liver cancer |
US10738363B2 (en) | 2016-08-31 | 2020-08-11 | National Central University | Analyzer and analytical method for predicting prognosis of cancer radiotherapy |
DE102018110526A1 (de) | 2018-05-02 | 2019-11-07 | Faurecia Autositze Gmbh | Verfahren zur Montage eines Linearaktuators für einen Kraftfahrzeugsitz |
CN108630317B (zh) * | 2018-05-09 | 2022-04-15 | 中国科学院昆明动物研究所 | 一种基于多基因表达特征谱的肝癌个性化预后评估方法 |
CN108648826B (zh) * | 2018-05-09 | 2022-04-15 | 中国科学院昆明动物研究所 | 一种基于多基因表达特征谱的胰腺癌个性化预后评估方法 |
CN108320806B (zh) * | 2018-05-09 | 2022-04-12 | 中国科学院昆明动物研究所 | 一种基于多基因表达特征谱的结肠癌个性化预后评估方法 |
CN108470111B (zh) * | 2018-05-09 | 2022-01-18 | 中国科学院昆明动物研究所 | 一种基于多基因表达特征谱的胃癌个性化预后评估方法 |
CN108363907B (zh) * | 2018-05-09 | 2022-01-18 | 中国科学院昆明动物研究所 | 一种基于多基因表达特征谱的肺腺癌个性化预后评估方法 |
CN108611416B (zh) * | 2018-05-09 | 2020-12-29 | 中国科学院昆明动物研究所 | 一种基于多基因表达特征谱的宫颈癌个性化预后评估方法 |
CN108733980B (zh) * | 2018-05-09 | 2022-01-18 | 中国科学院昆明动物研究所 | 基于多基因表达特征谱胶质母细胞瘤个性化预后评估方法 |
CN108647493B (zh) * | 2018-05-09 | 2022-01-18 | 中国科学院昆明动物研究所 | 一种肾透明细胞癌个性化预后评估方法 |
US11410745B2 (en) * | 2018-06-18 | 2022-08-09 | International Business Machines Corporation | Determining potential cancer therapeutic targets by joint modeling of survival events |
TWI758670B (zh) * | 2018-12-24 | 2022-03-21 | 奎克生技光電股份有限公司 | 健康風險評估方法 |
CN111172285A (zh) * | 2020-02-26 | 2020-05-19 | 江南大学附属医院 | 用于胰腺癌早期诊断和/或预后监测的miRNA组及其应用 |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU2003273921A1 (en) | 2002-09-27 | 2004-04-19 | Oridis Biomed Forschungs-Und Entwicklungs Gmbh | Polypeptides and nucleic acids encoding these and their use for the prevention,diagnosis or treatment of liver disorders and epithelial cancer |
CN102304570B (zh) | 2002-11-13 | 2015-01-21 | 托马斯杰斐逊大学 | 用于癌症诊断和治疗的组合物和方法 |
WO2005078139A2 (en) | 2004-02-09 | 2005-08-25 | Thomas Jefferson University | DIAGNOSIS AND TREATMENT OF CANCERS WITH MicroRNA LOCATED IN OR NEAR CANCER-ASSOCIATED CHROMOSOMAL FEATURES |
US20050272067A1 (en) | 2004-03-10 | 2005-12-08 | Macina Roberto A | Compositions, splice variants and methods relating to cancer specific genes and proteins |
US20060078913A1 (en) | 2004-07-16 | 2006-04-13 | Macina Roberto A | Compositions, splice variants and methods relating to cancer specific genes and proteins |
US20070065844A1 (en) | 2005-06-08 | 2007-03-22 | Massachusetts Institute Of Technology | Solution-based methods for RNA expression profiling |
-
2008
- 2008-04-09 WO PCT/US2008/059767 patent/WO2008124777A1/en active Application Filing
- 2008-04-09 TW TW097112898A patent/TWI367949B/zh not_active IP Right Cessation
- 2008-04-09 KR KR1020097023492A patent/KR20100027102A/ko not_active Application Discontinuation
- 2008-04-09 JP JP2010503183A patent/JP2010523156A/ja not_active Withdrawn
- 2008-04-09 CA CA2695868A patent/CA2695868A1/en not_active Abandoned
- 2008-04-09 EP EP08745383A patent/EP2134874A4/en not_active Withdrawn
- 2008-04-09 CN CN200880011562A patent/CN101688240A/zh active Pending
- 2008-04-09 MX MX2009010899A patent/MX2009010899A/es not_active Application Discontinuation
- 2008-04-09 AU AU2008237036A patent/AU2008237036A1/en not_active Abandoned
- 2008-04-09 US US12/100,113 patent/US7745134B2/en not_active Expired - Fee Related
- 2008-04-09 RU RU2009141359/14A patent/RU2009141359A/ru not_active Application Discontinuation
-
2009
- 2009-10-01 IL IL201298A patent/IL201298A0/en unknown
- 2009-10-08 CO CO09111661A patent/CO6231056A2/es not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
US20080254473A1 (en) | 2008-10-16 |
WO2008124777A1 (en) | 2008-10-16 |
US7745134B2 (en) | 2010-06-29 |
AU2008237036A2 (en) | 2010-09-09 |
EP2134874A4 (en) | 2010-12-22 |
AU2008237036A1 (en) | 2008-10-16 |
KR20100027102A (ko) | 2010-03-10 |
RU2009141359A (ru) | 2011-05-20 |
CO6231056A2 (es) | 2010-12-20 |
TWI367949B (en) | 2012-07-11 |
EP2134874A1 (en) | 2009-12-23 |
IL201298A0 (en) | 2010-05-31 |
TW200912002A (en) | 2009-03-16 |
CA2695868A1 (en) | 2008-10-16 |
CN101688240A (zh) | 2010-03-31 |
JP2010523156A (ja) | 2010-07-15 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
HH | Correction or change in general | ||
FA | Abandonment or withdrawal |