CN101687044B - 用于口服给药的治疗剂的制剂和相关方法 - Google Patents

用于口服给药的治疗剂的制剂和相关方法 Download PDF

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CN101687044B
CN101687044B CN200880023444.XA CN200880023444A CN101687044B CN 101687044 B CN101687044 B CN 101687044B CN 200880023444 A CN200880023444 A CN 200880023444A CN 101687044 B CN101687044 B CN 101687044B
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preparation
fatty acid
amphotericin
ampb
formulations
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CN101687044A (zh
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K·M·沃桑
E·K·沃桑
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University of British Columbia
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    • A—HUMAN NECESSITIES
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
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    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
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    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
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    • A61K47/24—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
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    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
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  • Heart & Thoracic Surgery (AREA)
  • Virology (AREA)
  • Transplantation (AREA)
  • Otolaryngology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
CN200880023444.XA 2007-05-25 2008-05-23 用于口服给药的治疗剂的制剂和相关方法 Active CN101687044B (zh)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US94030707P 2007-05-25 2007-05-25
US60/940,307 2007-05-25
US97670807P 2007-10-01 2007-10-01
US60/976,708 2007-10-01
US4147808P 2008-04-01 2008-04-01
US61/041,478 2008-04-01
PCT/CA2008/000975 WO2008144888A1 (en) 2007-05-25 2008-05-23 Formulations for the oral administration of therapeutic agents and related methods

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CN101687044A CN101687044A (zh) 2010-03-31
CN101687044B true CN101687044B (zh) 2014-10-29

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US (2) US8592382B2 (https=)
EP (1) EP2164518B1 (https=)
JP (1) JP5501224B2 (https=)
KR (3) KR20150064232A (https=)
CN (1) CN101687044B (https=)
CA (1) CA2688036C (https=)
IL (1) IL202111A (https=)
MX (1) MX2009012782A (https=)
NZ (1) NZ582332A (https=)
RU (1) RU2485975C2 (https=)
WO (1) WO2008144888A1 (https=)
ZA (1) ZA200908928B (https=)

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JP2010527940A (ja) 2010-08-19
HK1142823A1 (en) 2010-12-17
RU2009148315A (ru) 2011-06-27
NZ582332A (en) 2012-02-24
IL202111A0 (en) 2010-06-16
US8592382B2 (en) 2013-11-26
CN101687044A (zh) 2010-03-31
CA2688036C (en) 2016-08-16
JP5501224B2 (ja) 2014-05-21
KR20150064232A (ko) 2015-06-10
MX2009012782A (es) 2010-03-04
EP2164518A1 (en) 2010-03-24
EP2164518A4 (en) 2012-09-05
ZA200908928B (en) 2014-05-28
US20140228308A1 (en) 2014-08-14
WO2008144888A1 (en) 2008-12-04
AU2008255525A1 (en) 2008-12-04
CA2688036A1 (en) 2008-12-04
RU2485975C2 (ru) 2013-06-27
EP2164518B1 (en) 2019-04-24
KR20100017928A (ko) 2010-02-16
IL202111A (en) 2015-06-30
KR20160029866A (ko) 2016-03-15
US20100273728A1 (en) 2010-10-28

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