CN101678355B - 处理液体样品的装置 - Google Patents

处理液体样品的装置 Download PDF

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Publication number
CN101678355B
CN101678355B CN200880012452.4A CN200880012452A CN101678355B CN 101678355 B CN101678355 B CN 101678355B CN 200880012452 A CN200880012452 A CN 200880012452A CN 101678355 B CN101678355 B CN 101678355B
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CN
China
Prior art keywords
liquid sample
flow
different
flow paths
liquid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CN200880012452.4A
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English (en)
Chinese (zh)
Other versions
CN101678355A (zh
Inventor
D·伯格曼
P·克鲁杰
D·朗霍尔姆
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
J Remsen International Assets LLC
J&j Jsc
Original Assignee
Amic AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Amic AB filed Critical Amic AB
Publication of CN101678355A publication Critical patent/CN101678355A/zh
Application granted granted Critical
Publication of CN101678355B publication Critical patent/CN101678355B/zh
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

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    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502746—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by the means for controlling flow resistance, e.g. flow controllers, baffles or throttle valves
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/50273—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by the means or forces applied to move the fluids
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
    • F16K—VALVES; TAPS; COCKS; ACTUATING-FLOATS; DEVICES FOR VENTING OR AERATING
    • F16K99/00—Subject matter not provided for in other groups of this subclass
    • F16K99/0001—Microvalves
    • F16K99/0003—Constructional types of microvalves; Details of the cutting-off member
    • F16K99/0017—Capillary or surface tension valves, e.g. using electro-wetting or electro-capillarity effects
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0809—Geometry, shape and general structure rectangular shaped
    • B01L2300/0816—Cards, e.g. flat sample carriers usually with flow in two horizontal directions
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0887—Laminated structure
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0406—Moving fluids with specific forces or mechanical means specific forces capillary forces
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/08—Regulating or influencing the flow resistance
    • B01L2400/084—Passive control of flow resistance
    • B01L2400/086—Passive control of flow resistance using baffles or other fixed flow obstructions
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
    • F16K—VALVES; TAPS; COCKS; ACTUATING-FLOATS; DEVICES FOR VENTING OR AERATING
    • F16K99/00—Subject matter not provided for in other groups of this subclass
    • F16K2099/0082—Microvalves adapted for a particular use
    • F16K2099/0084—Chemistry or biology, e.g. "lab-on-a-chip" technology

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Mechanical Engineering (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Sampling And Sample Adjustment (AREA)
CN200880012452.4A 2007-04-16 2008-04-15 处理液体样品的装置 Expired - Fee Related CN101678355B (zh)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US92379807P 2007-04-16 2007-04-16
SE0700930A SE529978C2 (sv) 2007-04-16 2007-04-16 Analysanordning för vätskeformiga prov
SE07009301 2007-04-16
SE0700930-1 2007-04-16
US60/923,798 2007-04-16
PCT/SE2008/050424 WO2008127191A1 (en) 2007-04-16 2008-04-15 Device for handling liquid samples

Publications (2)

Publication Number Publication Date
CN101678355A CN101678355A (zh) 2010-03-24
CN101678355B true CN101678355B (zh) 2012-11-14

Family

ID=38935813

Family Applications (1)

Application Number Title Priority Date Filing Date
CN200880012452.4A Expired - Fee Related CN101678355B (zh) 2007-04-16 2008-04-15 处理液体样品的装置

Country Status (6)

Country Link
EP (1) EP2134472A4 (https=)
JP (1) JP5425757B2 (https=)
CN (1) CN101678355B (https=)
CA (1) CA2683920C (https=)
SE (1) SE529978C2 (https=)
WO (1) WO2008127191A1 (https=)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9216413B2 (en) 2009-07-07 2015-12-22 Boehringer Ingelheim Microparts Gmbh Plasma separation reservoir
KR20130085991A (ko) 2012-01-20 2013-07-30 오르토-클리니칼 다이아그노스틱스, 인코포레이티드 코너 주위의 균일한 유동을 갖는 분석 장치
US20130210036A1 (en) * 2012-01-20 2013-08-15 Ortho-Clinical Diagnostics, Inc. Controlling Fluid Flow Through An Assay Device
JP6278772B2 (ja) * 2014-03-19 2018-02-14 テルモ株式会社 血糖値測定用チップ
EP3226003A4 (en) * 2014-11-28 2018-06-20 Toyo Seikan Group Holdings, Ltd. Micro liquid transfer structure and analysis device
CN107219170B (zh) * 2017-07-24 2023-09-19 苏州鼎实医疗科技有限公司 试剂片
WO2022058470A1 (en) * 2020-09-17 2022-03-24 Katholieke Universiteit Leuven Activation and pressure balancing mechanism
US20240328957A1 (en) * 2023-04-03 2024-10-03 Burst Diagnostics Llc Chemiluminescence microfluidic immunoassay device and methods of use thereof

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6296020B1 (en) * 1998-10-13 2001-10-02 Biomicro Systems, Inc. Fluid circuit components based upon passive fluid dynamics
CN1540335A (zh) * 2003-11-01 2004-10-27 浙江大学 集成微型电磁泵式毛细管电泳芯片
EP1525919A1 (en) * 2003-10-23 2005-04-27 F. Hoffmann-La Roche Ag Flow triggering device
GB2410086A (en) * 2004-01-14 2005-07-20 British Biocell Internat Ltd Assay devices having flow block(s) to determine flow of liquids
CN1933909A (zh) * 2004-03-24 2007-03-21 Amic公司 测定装置及方法
CN101010138A (zh) * 2004-06-02 2007-08-01 阿米克公司 控制流动的测定装置和方法

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0610900A (ja) * 1992-04-27 1994-01-21 Canon Inc 液体移動方法及び移動装置ならびにこれを利用した測定装置
US6156270A (en) * 1992-05-21 2000-12-05 Biosite Diagnostics, Inc. Diagnostic devices and apparatus for the controlled movement of reagents without membranes
JP3213566B2 (ja) * 1996-04-26 2001-10-02 アークレイ株式会社 検体分析用具およびそれを用いた検体分析方法並びに検体分析装置
US6571651B1 (en) * 2000-03-27 2003-06-03 Lifescan, Inc. Method of preventing short sampling of a capillary or wicking fill device
SE0201738D0 (sv) * 2002-06-07 2002-06-07 Aamic Ab Micro-fluid structures
KR100444751B1 (ko) * 2002-11-11 2004-08-16 한국전자통신연구원 표면장력에 의한 유체제어 소자
JPWO2004051228A1 (ja) * 2002-11-29 2006-04-06 日本電気株式会社 マイクロチップならびにこれを用いた送液方法、質量分析システム
DE10302720A1 (de) * 2003-01-23 2004-08-05 Steag Microparts Gmbh Mikrofluidischer Schalter zum Anhalten des Flüssigkeitsstroms während eines Zeitintervalls
EP1525916A1 (en) * 2003-10-23 2005-04-27 F. Hoffmann-La Roche Ag Flow triggering device
US20070160474A1 (en) * 2004-02-06 2007-07-12 Kazuhiro Iida Regulation structure, separation device and gradient forming device, and microchip using the same
US7682817B2 (en) * 2004-12-23 2010-03-23 Kimberly-Clark Worldwide, Inc. Microfluidic assay devices
EP1853911A1 (en) * 2005-02-25 2007-11-14 Inverness Medical Switzerland GmbH Fluidic gating device
JPWO2006098370A1 (ja) * 2005-03-16 2008-08-28 日本電気株式会社 流路の実効的な通過時間の調整機構を具える遅延回路、マイクロチップ、およびその作製方法

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6296020B1 (en) * 1998-10-13 2001-10-02 Biomicro Systems, Inc. Fluid circuit components based upon passive fluid dynamics
EP1525919A1 (en) * 2003-10-23 2005-04-27 F. Hoffmann-La Roche Ag Flow triggering device
CN1540335A (zh) * 2003-11-01 2004-10-27 浙江大学 集成微型电磁泵式毛细管电泳芯片
GB2410086A (en) * 2004-01-14 2005-07-20 British Biocell Internat Ltd Assay devices having flow block(s) to determine flow of liquids
CN1933909A (zh) * 2004-03-24 2007-03-21 Amic公司 测定装置及方法
CN101010138A (zh) * 2004-06-02 2007-08-01 阿米克公司 控制流动的测定装置和方法

Also Published As

Publication number Publication date
WO2008127191A1 (en) 2008-10-23
EP2134472A4 (en) 2014-10-01
SE0700930L (sv) 2008-01-22
CN101678355A (zh) 2010-03-24
EP2134472A1 (en) 2009-12-23
JP5425757B2 (ja) 2014-02-26
JP2010525319A (ja) 2010-07-22
SE529978C2 (sv) 2008-01-22
CA2683920C (en) 2016-05-31
CA2683920A1 (en) 2008-10-23

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C06 Publication
PB01 Publication
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SE01 Entry into force of request for substantive examination
C14 Grant of patent or utility model
GR01 Patent grant
TR01 Transfer of patent right

Effective date of registration: 20180706

Address after: Delaware

Patentee after: J Remsen international assets LLC

Address before: Solna, Sweden

Patentee before: J&J JSC

Effective date of registration: 20180706

Address after: Solna, Sweden

Patentee after: J&J JSC

Address before: uppsala

Patentee before: AMIC AB

TR01 Transfer of patent right
CF01 Termination of patent right due to non-payment of annual fee

Granted publication date: 20121114

CF01 Termination of patent right due to non-payment of annual fee