CN101674823A - 用于与增强的5-脂氧合酶和/或白三烯活性有关的疾病(例如哮喘)的r-齐留通 - Google Patents

用于与增强的5-脂氧合酶和/或白三烯活性有关的疾病(例如哮喘)的r-齐留通 Download PDF

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Publication number
CN101674823A
CN101674823A CN200880004777A CN200880004777A CN101674823A CN 101674823 A CN101674823 A CN 101674823A CN 200880004777 A CN200880004777 A CN 200880004777A CN 200880004777 A CN200880004777 A CN 200880004777A CN 101674823 A CN101674823 A CN 101674823A
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zileuton
daily dose
disease
syndrome
compositions
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CN200880004777A
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Chinese (zh)
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W·纽曼
A·库玛
L·利伯廷
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Chiesi USA Inc
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Critical Therapeutics Inc
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    • A61K31/33Heterocyclic compounds
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    • A61K31/381Heterocyclic compounds having sulfur as a ring hetero atom having five-membered rings
    • AHUMAN NECESSITIES
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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
CN200880004777A 2007-01-05 2008-01-04 用于与增强的5-脂氧合酶和/或白三烯活性有关的疾病(例如哮喘)的r-齐留通 Pending CN101674823A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US87927307P 2007-01-05 2007-01-05
US60/879,273 2007-01-05
PCT/US2008/000101 WO2008085875A2 (en) 2007-01-05 2008-01-04 R-zileuton for use in conditions associated with increased 5-lipoxygenase and/or leukotriene activity (eg asthma)

Publications (1)

Publication Number Publication Date
CN101674823A true CN101674823A (zh) 2010-03-17

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ID=39339861

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CN200880004777A Pending CN101674823A (zh) 2007-01-05 2008-01-04 用于与增强的5-脂氧合酶和/或白三烯活性有关的疾病(例如哮喘)的r-齐留通

Country Status (7)

Country Link
US (1) US20100273868A1 (enExample)
EP (1) EP2114399A2 (enExample)
JP (1) JP2010515682A (enExample)
CN (1) CN101674823A (enExample)
CA (1) CA2674492A1 (enExample)
MX (1) MX2009007247A (enExample)
WO (1) WO2008085875A2 (enExample)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101829075A (zh) * 2010-04-27 2010-09-15 中国人民解放军第三军医大学第一附属医院 苦柯胺a和苦柯胺b的用途
CN102274213A (zh) * 2010-06-10 2011-12-14 北京润德康医药技术有限公司 含有r(+)-齐留通的药用组合物
CN102429872A (zh) * 2011-11-25 2012-05-02 舒泰神(北京)生物制药股份有限公司 含齐留通的膜控型缓释微丸及其制备方法
CN116528901A (zh) * 2020-12-01 2023-08-01 瑞沃斯帕有限责任公司 用于治疗慢性阻塞性肺病、哮喘、肺炎、支气管炎、囊性纤维化和肺水肿的方法和组合物

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20120232031A1 (en) * 2009-10-19 2012-09-13 Panmira Pharmaceuticals, Llc Injectable formulations for intra-articular or peri-articular administration
EP2563359A1 (en) 2010-04-30 2013-03-06 Allergan, Inc. Novel treatment for age related macular degeneration and ocular ischemic disease associated with complement activation by targeting 5-lipoxygenase
ES2624710T3 (es) * 2011-08-23 2017-07-17 Cornerstone Therapeutics Inc. Uso de zileutón en el tratamiento de pólipos nasales en pacientes con fibrosis quística
GB201118193D0 (en) * 2011-10-21 2011-12-07 Jagotec Ag Improvements in or relating to oranic compounds
GB201118198D0 (en) * 2011-10-21 2011-12-07 Jagotec Ag Improvements in or relating to organic compounds
WO2016062277A1 (zh) * 2014-10-24 2016-04-28 朗齐生物医学股份有限公司 驱虫药用于制备抗癌医药组合物中的应用
CN107847468A (zh) * 2015-05-26 2018-03-27 纪念斯隆·凯特琳癌症中心 铁死亡和谷氨酰胺分解抑制剂及其治疗方法
WO2024044654A2 (en) * 2022-08-23 2024-02-29 University Of Houston System Parenteral compositions of zileuton and methods of use

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH08510252A (ja) * 1993-05-10 1996-10-29 セプラコール・インコーポレーテッド 光学的に純粋な(+)‐ジロイトンを用いた方法および組成
AU2007217770B2 (en) * 2006-02-21 2011-09-08 Cornerstone Therapeutics Inc. New crystal forms and pharmaceutical compositions of (+) -R-zileuton

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101829075A (zh) * 2010-04-27 2010-09-15 中国人民解放军第三军医大学第一附属医院 苦柯胺a和苦柯胺b的用途
CN101829075B (zh) * 2010-04-27 2011-07-20 中国人民解放军第三军医大学第一附属医院 苦柯胺a和苦柯胺b的用途
CN102274213A (zh) * 2010-06-10 2011-12-14 北京润德康医药技术有限公司 含有r(+)-齐留通的药用组合物
CN102429872A (zh) * 2011-11-25 2012-05-02 舒泰神(北京)生物制药股份有限公司 含齐留通的膜控型缓释微丸及其制备方法
CN116528901A (zh) * 2020-12-01 2023-08-01 瑞沃斯帕有限责任公司 用于治疗慢性阻塞性肺病、哮喘、肺炎、支气管炎、囊性纤维化和肺水肿的方法和组合物

Also Published As

Publication number Publication date
WO2008085875A3 (en) 2009-02-26
MX2009007247A (es) 2009-09-18
JP2010515682A (ja) 2010-05-13
CA2674492A1 (en) 2008-07-17
EP2114399A2 (en) 2009-11-11
US20100273868A1 (en) 2010-10-28
WO2008085875A2 (en) 2008-07-17

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