CN101622266B - 硫酸糖脂抗原、其制备方法及其抗结核病的用途 - Google Patents

硫酸糖脂抗原、其制备方法及其抗结核病的用途 Download PDF

Info

Publication number
CN101622266B
CN101622266B CN2008800060908A CN200880006090A CN101622266B CN 101622266 B CN101622266 B CN 101622266B CN 2008800060908 A CN2008800060908 A CN 2008800060908A CN 200880006090 A CN200880006090 A CN 200880006090A CN 101622266 B CN101622266 B CN 101622266B
Authority
CN
China
Prior art keywords
compound
formula
preparation
tuberculosis
methyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CN2008800060908A
Other languages
English (en)
Chinese (zh)
Other versions
CN101622266A (zh
Inventor
G·皮佐
J·普朗迪
M·吉勒龙
G·德里贝罗
J·吉亚尔
L·莫里
S·鲍利迪
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Centre National de la Recherche Scientifique CNRS
Original Assignee
Centre National de la Recherche Scientifique CNRS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Centre National de la Recherche Scientifique CNRS filed Critical Centre National de la Recherche Scientifique CNRS
Publication of CN101622266A publication Critical patent/CN101622266A/zh
Application granted granted Critical
Publication of CN101622266B publication Critical patent/CN101622266B/zh
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Images

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
    • C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
    • C07H13/04—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals attached to acyclic carbon atoms
    • C07H13/06—Fatty acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A61P31/06—Antibacterial agents for tuberculosis
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56911—Bacteria
    • G01N33/5695—Mycobacteria
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/195—Assays involving biological materials from specific organisms or of a specific nature from bacteria
    • G01N2333/35—Assays involving biological materials from specific organisms or of a specific nature from bacteria from Mycobacteriaceae (F)

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Genetics & Genomics (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Cell Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Oncology (AREA)
  • Food Science & Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
CN2008800060908A 2007-01-24 2008-01-11 硫酸糖脂抗原、其制备方法及其抗结核病的用途 Expired - Fee Related CN101622266B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP07290097.0 2007-01-24
EP07290097A EP1950218A1 (en) 2007-01-24 2007-01-24 Sulfoglycolipid antigens, their process of preparation, and their use against tuberculosis
PCT/IB2008/000053 WO2008090425A1 (en) 2007-01-24 2008-01-11 Sulfoglycolipid antigens, their process of preparation, and their use against tuberculosis

Publications (2)

Publication Number Publication Date
CN101622266A CN101622266A (zh) 2010-01-06
CN101622266B true CN101622266B (zh) 2013-09-11

Family

ID=38080940

Family Applications (1)

Application Number Title Priority Date Filing Date
CN2008800060908A Expired - Fee Related CN101622266B (zh) 2007-01-24 2008-01-11 硫酸糖脂抗原、其制备方法及其抗结核病的用途

Country Status (7)

Country Link
US (1) US8268801B2 (https=)
EP (2) EP1950218A1 (https=)
JP (1) JP5547491B2 (https=)
CN (1) CN101622266B (https=)
BR (1) BRPI0806400A8 (https=)
ES (1) ES2659516T3 (https=)
WO (1) WO2008090425A1 (https=)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8288509B2 (en) * 2002-02-22 2012-10-16 National Hospital Organization Kinki-chuo Chest Medical center Therapeutic agent for infections, and treatment method using the same
JP6195848B2 (ja) 2012-01-27 2017-09-13 ザ、リージェンツ、オブ、ザ、ユニバーシティ、オブ、カリフォルニアＴｈｅ Ｒｅｇｅｎｔｓ Ｏｆ Ｔｈｅ Ｕｎｉｖｅｒｓｉｔｙ Ｏｆ Ｃａｌｉｆｏｒｎｉａ 糖ポリマーを用いた生体分子の安定化
JP5945756B1 (ja) * 2015-06-01 2016-07-05 マイクロ波化学株式会社 ショ糖脂肪酸エステルの製造方法
JP6276806B2 (ja) * 2016-05-30 2018-02-07 マイクロ波化学株式会社 ショ糖脂肪酸エステルの製造方法
CN106488925B (zh) * 2015-06-01 2019-04-23 微波化学有限公司 蔗糖脂肪酸酯的制造方法
JP5952980B1 (ja) * 2016-02-17 2016-07-13 マイクロ波化学株式会社 ショ糖ステアリン酸エステルの製造方法
NL2017204B1 (en) * 2016-06-08 2017-12-18 Kei International Ltd Solid substrate comprising antigens immobilised thereto, biosensor comprising said solid substrate and method for detecting the presence of mycobacterial material in a sample
NL2016913B1 (en) * 2016-06-08 2017-12-18 Kei International Ltd Solid substrate comprising antigens immobilised thereto and use thereof in a method for detecting the presence of mycobacterial material in a sample
WO2017211314A1 (en) 2016-06-08 2017-12-14 Kei International Limited Method for detecting presence of mycobacterial material in sample using immobilised mannosyl phosphoketide antigen
NL2021443B1 (en) 2018-08-08 2020-02-20 Kei International Ltd Synthetic antigens for tuberculosis detection
NL2022166B1 (en) 2018-12-10 2020-07-02 Kei International Ltd Nitrocellulose sheet comprising immobilized immunoglobulins and lipid based antigens and use thereof
FR3092112B1 (fr) 2019-01-29 2023-01-06 Arkema France Huile de base lubrifiante synthetisee a partir d’esters de polyols et d’acides gras biosources
FR3092113B1 (fr) * 2019-01-29 2023-04-21 Arkema France Huile de base lubrifiante synthetisee a partir desters d’alcool de sucre

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1469007A1 (en) * 2003-04-18 2004-10-20 Centre National De La Recherche Scientifique (Cnrs) Sulfoglycolipid antigens, their extraction from mycobacterieum tuberculosis, and their use against tuberculosis

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
Isabelle Vergne，et al.Interaction of Mycobacterial Glycolipids with host cells..《Frontiers in Bioscience》.1998,第3卷第866页图1，第868页图2，图3. *
Martine Gilleron,et al.Diacylated Sulfoglycolipids Are Novel Mycobacterial Antigens Stimulating CD1-restricted T Cells during Infection with Mycobacterium tuberculosis ..《The Journal of Experimental Medicine》.2004,第199卷(第5期),第649页第1段至657页最后1段,尤其是第652页图1. *
侯伟 等.两种糖脂抗原在结核病血清诊断中的应用.《中国医学科学院学报》.1994,第16卷(第5期),第374页第1段至第376页第2段. *

Also Published As

Publication number Publication date
JP2010516748A (ja) 2010-05-20
BRPI0806400A8 (pt) 2018-10-23
EP2125849B1 (en) 2017-11-15
ES2659516T3 (es) 2018-03-16
US8268801B2 (en) 2012-09-18
CN101622266A (zh) 2010-01-06
WO2008090425A1 (en) 2008-07-31
US20100166801A1 (en) 2010-07-01
EP1950218A1 (en) 2008-07-30
JP5547491B2 (ja) 2014-07-16
BRPI0806400A2 (pt) 2011-09-06
EP2125849A1 (en) 2009-12-02

Similar Documents

Publication Publication Date Title
CN101622266B (zh) 硫酸糖脂抗原、其制备方法及其抗结核病的用途
JP2010516748A5 (https=)
JP7360385B2 (ja) ブラルテミシン類似体
EP3019513B1 (en) Synthetic vaccines against streptococcus pneumoniae type 1
CN111448204A (zh) 抗肺炎克雷伯菌的疫苗
JP2017503863A (ja) クローン病などの大腸菌誘発性炎症性腸疾患治療用の経口摂取可能な化合物、これを調製するプロセスおよび付着防止薬としての使用
Liav et al. A new synthesis of cord factors and analogs
CN108367059A (zh) 针对肺炎链球菌血清型2的合成疫苗
Shimoyama et al. Chemical synthesis and immunomodulatory functions of bacterial lipid as
US10207006B2 (en) Oligosaccharide conjugates and methods of use
Mohammed et al. Arabino mycolates from synthetic mycolic acids
JP2014507450A (ja) 合成ｌｔａ模倣物、並びにグラム陽性感染症の治療及び／又は予防のためのワクチン成分としてのその使用
Matsuba et al. Association of the Rv0679c protein with lipids and carbohydrates in Mycobacterium tuberculosis/Mycobacterium bovis BCG
Mhamane et al. Design, synthesis and biological evaluation of novel lipophilic 2, 5-disubstituted tetrazole analogues of muramyl dipeptide as NOD2 agonists
EP4656648A1 (en) Immunomodulatory thiourea and urea carbohydrate compounds and uses thereof
García Fernández et al. Immunomodulatory thiourea and urea carbohydrate compounds and uses thereof
Dutta et al. Chemical Synthesis of the Pentasaccharide Related to the Exopolysaccharide of Aeromonas veronii bv. Sobria Strain K49
JP2011500540A (ja) 放線菌類グリセロールアシル誘導体抗原を含む医薬組成物、それらの抽出プロセス、及び結核に対するそれらの使用
Marino et al. Marino
WO2025215228A1 (en) Synthetic vaccines against porphyromonas gingivalis
KR20230106604A (ko) 신규 아미노알킬글루코사미니드 4-인산 유도체
CN114989149A (zh) 嘧啶类化合物及其制备方法、药物组合物和应用

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C14 Grant of patent or utility model
GR01 Patent grant
CF01 Termination of patent right due to non-payment of annual fee
CF01 Termination of patent right due to non-payment of annual fee

Granted publication date: 20130911

Termination date: 20200111