CN101622248B - 用作axl抑制剂的n3-杂芳基取代的三唑和n5-杂芳基取代的三唑 - Google Patents

用作axl抑制剂的n3-杂芳基取代的三唑和n5-杂芳基取代的三唑 Download PDF

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CN101622248B
CN101622248B CN2007800489092A CN200780048909A CN101622248B CN 101622248 B CN101622248 B CN 101622248B CN 2007800489092 A CN2007800489092 A CN 2007800489092A CN 200780048909 A CN200780048909 A CN 200780048909A CN 101622248 B CN101622248 B CN 101622248B
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optionally substituted
triazole
diamines
pyrimidine
thiotolene
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CN101622248A (zh
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戴恩·高夫
张静
拉金德尔·辛格
萨卡·霍兰
余家新
希洛·海克洛特
丁平羽
乔尼·李特瓦克
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Rigel Pharmaceuticals Inc
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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
CN2007800489092A 2006-12-29 2007-12-28 用作axl抑制剂的n3-杂芳基取代的三唑和n5-杂芳基取代的三唑 Expired - Fee Related CN101622248B (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US88287506P 2006-12-29 2006-12-29
US60/882,875 2006-12-29
US97544307P 2007-09-26 2007-09-26
US60/975,443 2007-09-26
PCT/US2007/089153 WO2008083354A1 (en) 2006-12-29 2007-12-28 N3-heteroaryl substituted triazoles and n5-heteroaryl substituted triazoles useful as axl inhibitors

Publications (2)

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CN101622248A CN101622248A (zh) 2010-01-06
CN101622248B true CN101622248B (zh) 2013-04-17

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US (2) US9650391B2 (https=)
EP (2) EP2074115B1 (https=)
JP (2) JP5567837B2 (https=)
CN (1) CN101622248B (https=)
AU (1) AU2007342005A1 (https=)
CA (1) CA2710046C (https=)
ES (2) ES2672172T3 (https=)
WO (1) WO2008083354A1 (https=)

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US8796259B2 (en) 2014-08-05
HK1174631A1 (en) 2013-06-14
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CN101622248A (zh) 2010-01-06
US20080182862A1 (en) 2008-07-31
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