CN101601787A - The composition and method of making the same of treatment bronchial asthma - Google Patents

The composition and method of making the same of treatment bronchial asthma Download PDF

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Publication number
CN101601787A
CN101601787A CNA2008100434734A CN200810043473A CN101601787A CN 101601787 A CN101601787 A CN 101601787A CN A2008100434734 A CNA2008100434734 A CN A2008100434734A CN 200810043473 A CN200810043473 A CN 200810043473A CN 101601787 A CN101601787 A CN 101601787A
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CN
China
Prior art keywords
bronchial asthma
treatment
prepared
compositions
rhizoma pinelliae
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Pending
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CNA2008100434734A
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Chinese (zh)
Inventor
王勇
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SHANGHAI YOUSEEN NEW MEDICINE EXPLOITATION CO Ltd
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SHANGHAI YOUSEEN NEW MEDICINE EXPLOITATION CO Ltd
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Priority to CNA2008100434734A priority Critical patent/CN101601787A/en
Publication of CN101601787A publication Critical patent/CN101601787A/en
Pending legal-status Critical Current

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Abstract

The present invention sets foot in field of medicaments, is a kind of compositions for the treatment of bronchial asthma specifically.This Chinese medicine composition is made up of Herba Ephedrae, Radix Peucedani, Folium Isatidis, Rhizoma Pinelliae Preparata, Flos Inulae.The present invention also provides the preparation method of this Chinese medicine composition.

Description

The composition and method of making the same of treatment bronchial asthma
Technical field
The invention belongs to field of medicaments, be specifically related to a kind of compositions for the treatment of bronchial asthma; The preparation method that also relates to said composition.
Background technology
China's sampling survey in 2000 shows that bronchial asthma average prevalence in urban children is 1.97%, obviously increases before 10 years, and the sick increase of rate is sent out up to 1-2 doubly in cities such as Beijing, Shanghai, Tianjin.Bronchial asthma is modal chronic disease of Childhood, and ill crowd is based on preschool and school age population, and 70% child the age of symptoms of asthma occurs first below 3 years old, and the delay of the childhood asthma of nearly 1/3-1/2 is to the adult.At present, bronchial asthma has become the prevalence maximum medical care problem of child crowd that rises year by year, gets involved.
The pathogeny of bronchial asthma is a chronic airway inflammation, increase to the master with bronchial mucosa edema, bronchial muscular spasm companion mucous secretion, and the capillary bronchus is with slough filling in the bronchioles, myxedema and cause the stingy road of popularity ventilatory function obstacle, this allergy airway inflammation, make the susceptible person have high response to various motivating factors, and cause the air flue constriction, and cause airflow limited, occur panting, symptom such as tachypnea, uncomfortable in chest, cough.
Its treatment is along with the pathogenetic correct understanding of primary disease is increased.At present, medical circle generally adopts suction " glucocorticoid ", with prevention with alleviate the swelling of air flue and reduce in the lung mucous secretion and treat asthma, with the cooperation antibiotic therapy that infects.But, have only 5% in time to obtain suction " glucocorticoid " treatment among the child so make a definite diagnosis at present because many heads of a family are reluctant that infant uses hormone.And most heads of a family select Chinese medicine or therapy of combining Chinese and Western medicine asthmatic bronchitis and bronchial asthma.
Treatment by Chinese herbs bronchial asthma has long history in China.On therapeutic effect, has special advantages.
Summary of the invention
At the above-mentioned deficiency of prior art, one of technical problem to be solved by this invention is that a kind of Chinese medicine composition for the treatment of bronchial asthma is provided.
Two of technical problem to be solved by this invention is that a kind of preparation method of Chinese medicine composition of above-mentioned treatment bronchial asthma is provided.
The present invention for the technical scheme that solves its technical problem one and adopt is: the compositions of treatment bronchial asthma is the medicament that is prepared from by the following weight proportion raw material, and this medicament is a said dosage form on any pharmaceutics.
Herba Ephedrae 1-5 part Radix Peucedani 1-5 part Folium Isatidis 5-9 part Rhizoma Pinelliae Preparata 3-7 part Flos Inulae 2-6 part
As the preferred technical solution of the present invention, the preferred following weight proportion raw material preparation of compositions:
Herba Ephedrae 2-4 part Radix Peucedani 2-4 part Folium Isatidis 6-8 part Rhizoma Pinelliae Preparata 4-6 part Flos Inulae 3-5 part
As more preferably technical scheme of the present invention, the more preferably following weight proportion raw material preparation of the compositions of above-mentioned treatment asthmatic bronchitis and bronchial asthma:
4 parts of 5 parts of Flos Inulaes of 7 parts of Rhizoma Pinelliae Preparata of 3 portions of Folium Isatidiss of 3 parts of Radix Peucedanis of Herba Ephedrae
The traditional Chinese medical science is to the understanding of bronchial asthma: " lung being a delicate viscus occupies postcibal vomiting, closes fur outward, and interior department breathes, the gas of main the whole body, department's respectful making clearly ".So-called " tender dirty " person is easy to be subjected to heresy also with its sensitivity.The invasion of six evil, attacking the lung first occupies the part of the body cavity above the diaphragm housing the heart and lungs with lung, closes fur outward.Ancient claim " space between skin and muscles " of fur, interspaces of skin and muscles being loose, exopathogen is easily invaded.Hypopnea appears in impairment of dispersing and descending function of the lung then in exopathogen is gone into, and coughs, pants.In addition, lung regulating fluid apssage malfunction can't move body fluid to whole body, causes the water liquid of internal metabolism not excrete, and gives birth to expectorant then.Expectorant is stopped up air flue, and breathing is obstructed, the aggravation of panting.
The present composition is gone into lung, bladder two warps according to the principle of the traditional Chinese medical science " symptomatic treatment in acute condition, relieving the primary symptom in a chronic case " with Herba Ephedrae, can declare smooth lung qi, and antiasthmatic-antitussive is the key medicine of relievining asthma.Be equipped with lowering the adverse-rising QI to resolve phlegm Hu, Rhizoma Pinelliae Preparata, Flos Inulae before, wherein Radix Peucedani is worked hard and is trembled with fear, and the effect of lung qi dispersing is arranged, the preventing phlegm from forming and stopping coughing of kind energy; The Rhizoma Pinelliae is gone into the taste warp, and drying dampness to eliminate phlegm is for controlling the key medicine of various phlegm syndromes; Flos Inulae is gone into lung meridian, and property belongs to sedimentation, and the drink that can reduce phlegm, following lung qi are applicable to that expectorant stops up the disease of the cough with asthma abundant expectoration due to the QI rising in reverse order, can play the mutual reinforcement between effect with Rhizoma Pinelliae compatibility.The clear eliminating the pathogens from the lung heat of Folium Isatidis is improved the absorption that blood circulation promotes the inflammation material.So full side has the function of heat-clearing and toxic substances removing, resolving phlegm and relieving asthma, is applicable to child's bronchial asthma.
Two of the technical problem to be solved in the present invention is, the present composition is pediatric pharmaceuticals for convenience, has selected granule, and the preparation method of its technical scheme comprises the steps: to get the above-mentioned raw materials medicine, add 8-10 times of water gaging and decoct secondary, each 3 hours, collecting decoction staticly settled, filter, being concentrated into relative density is the thick extractum of 1.3-1.4, adds conventional adjuvant and flavoring agent, makes granule.
Innovative point of the present invention and advantage:
Present composition technology can realize industrialized great production, and the granule of making is convenient for carrying and takes.
Clinical experiment is the result show: from traditional Chinese medical science cardinal symptom observation of curative effect, primary symptom is panted, wheezing, expectorant sound after treatment, treatment group and matched group total effective rate all reach more than 70%.Treatment group resolve phlegm effect is particularly evident, and obvious effective rate reaches 60%, and effective percentage reaches 80%, compare with matched group, and through the variance check, P<0.05, there were significant differences.
The specific embodiment
Below in conjunction with embodiment content of the present invention is described further.
Embodiment 1
Get Herba Ephedrae 1000g, Radix Peucedani 1000g, Folium Isatidis 5000g, Rhizoma Pinelliae Preparata 3000g, Flos Inulae 2000g, add 8 times of water gagings and decoct secondary, each 3 hours, collecting decoction staticly settles, and filters, being concentrated into relative density is the thick extractum of 1.3-1.4, adds conventional adjuvant and flavoring agent, makes granule.
Embodiment 2
Get Herba Ephedrae 5000g, Radix Peucedani 5000g, Folium Isatidis 9000g, Rhizoma Pinelliae Preparata 7000g, Flos Inulae 6000g, add 10 times of water gagings and decoct secondary, each 3 hours, collecting decoction staticly settles, and filters, being concentrated into relative density is the thick extractum of 1.3-1.4, adds conventional adjuvant and flavoring agent, makes granule.
Embodiment 3
Get Herba Ephedrae 2000g, Radix Peucedani 2000g, Folium Isatidis 6000g, Rhizoma Pinelliae Preparata 4000g, Flos Inulae 3000g, add 9 times of water gagings and decoct secondary, each 3 hours, collecting decoction staticly settles, and filters, being concentrated into relative density is the thick extractum of 1.3-1.4, adds conventional adjuvant and flavoring agent, makes granule.
Embodiment 4
Get Herba Ephedrae 4000g, Radix Peucedani 4000g, Folium Isatidis 8000g, Rhizoma Pinelliae Preparata 6000g, Flos Inulae 5000g, add 9 times of water gagings and decoct secondary, each 3 hours, collecting decoction staticly settles, and filters, being concentrated into relative density is the thick extractum of 1.3-1.4, adds conventional adjuvant and flavoring agent, makes granule.
Embodiment 5
Get Herba Ephedrae 3000g, Radix Peucedani 3000g, Folium Isatidis 7000g, Rhizoma Pinelliae Preparata 5000g, Flos Inulae 4000g, add 9 times of water gagings and decoct secondary, each 3 hours, collecting decoction staticly settles, and filters, being concentrated into relative density is the thick extractum of 1.3-1.4, adds conventional adjuvant and flavoring agent, makes granule.

Claims (4)

1. compositions for the treatment of bronchial asthma is characterized in that being prepared from by following crude drug:
Herba Ephedrae 1-5 part Radix Peucedani 1-5 part Folium Isatidis 5-9 part Rhizoma Pinelliae Preparata 3-7 part Flos Inulae 2-6 part.
2. a kind of compositions for the treatment of bronchial asthma as claimed in claim 1 is characterized in that being prepared from by following crude drug: Herba Ephedrae 2-4 part Radix Peucedani 2-4 part Folium Isatidis 6-8 part Rhizoma Pinelliae Preparata 4-6 part Flos Inulae 3-5 part.
3. a kind of compositions for the treatment of bronchial asthma as claimed in claim 1 is characterized in that being prepared from by following crude drug: 4 parts of 5 parts of Flos Inulaes of 7 parts of Rhizoma Pinelliae Preparata of 3 portions of Folium Isatidiss of 3 parts of Radix Peucedanis of Herba Ephedrae.
4. as a kind of compositions for the treatment of bronchial asthma of claim 1 or 2 or 3, it is characterized in that being prepared into: get the above-mentioned raw materials medicine according to the method for being prepared as follows, add 8-10 times of water gaging and decoct secondary, each 3 hours, collecting decoction staticly settled, filter, being concentrated into relative density is the thick extractum of 1.3-1.4, adds conventional adjuvant and flavoring agent, makes granule.
CNA2008100434734A 2008-06-11 2008-06-11 The composition and method of making the same of treatment bronchial asthma Pending CN101601787A (en)

Priority Applications (1)

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CNA2008100434734A CN101601787A (en) 2008-06-11 2008-06-11 The composition and method of making the same of treatment bronchial asthma

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CN101601787A true CN101601787A (en) 2009-12-16

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104288608A (en) * 2014-10-20 2015-01-21 肥西县昌玖木本油料种植专业合作社 Inula flower effervescent tablet and preparation method thereof
CN104689077A (en) * 2015-03-27 2015-06-10 吴斌 Traditional Chinese preparation for curing cough-type asthma and preparing method
CN105497013A (en) * 2015-12-16 2016-04-20 天津医科大学 Application of sesquiterpenoids to preparation of anti-asthmatic drug

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104288608A (en) * 2014-10-20 2015-01-21 肥西县昌玖木本油料种植专业合作社 Inula flower effervescent tablet and preparation method thereof
CN104689077A (en) * 2015-03-27 2015-06-10 吴斌 Traditional Chinese preparation for curing cough-type asthma and preparing method
CN105497013A (en) * 2015-12-16 2016-04-20 天津医科大学 Application of sesquiterpenoids to preparation of anti-asthmatic drug
CN105497013B (en) * 2015-12-16 2018-04-27 天津医科大学 Application of the sesquiterpenoids in anti-asthma disease medicine is prepared

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Open date: 20091216