CN102793841B

CN102793841B - Traditional Chinese medicine composition for treating pediatric acute bronchitis

Info

Publication number: CN102793841B
Application number: CN2012103164466A
Authority: CN
Inventors: 孔庆玉
Original assignee: Individual
Current assignee: Individual
Priority date: 2012-08-20
Filing date: 2012-08-20
Publication date: 2013-11-20
Anticipated expiration: 2032-08-20
Also published as: CN102793841A

Abstract

The invention discloses a traditional Chinese medicine composition for treating pediatric acute bronchitis. The pediatric acute bronchitis is traditional Chinese medicine exogenous cough and is formed in such a manner that exogenous cold or exogenous cold invasion is converted from stagnation into heat and aggravated to generate asthma. Thereby, the traditional Chinese medicine composition is prepared by traditional Chinese medicine crepis phoenix, marsdenia tenacissima, adenophora trachelioides, brassica alba boiss, thunberg fritillary bulb, cortex mori radicis, adenophora tetraphylla, platycodon grandiflorum, and liquorice with the effects of dispersing lung qi, and eliminating phlegm and relieving coughing into decoction. The traditional Chinese medicine composition has the beneficial effects that through the clinical test, the total effective rate reaches 97.1 percent, cases in a treatment group are quick in abatement of fever, and symptom improved cases in the treatment group are also remarkably more than those in a contrast group.

Description

A kind of Chinese medicine composition for the treatment of infantile acute bronchitis

Technical field

The present invention relates to a kind of Chinese medicine composition, relate in particular to a kind of Chinese medicine composition for the treatment of infantile bronchitis.

Background technology

Infantile acute bronchitis is mainly in the children's below 1 years old, and especially below 6 months, the baby is common.The general four seasons all can fall ill, but comparatively common to fall ill in winter, spring, are child's commonly encountered diseases in period, frequently-occurring disease.Mostly be being invaded by exogenous pathogen, impairment of purifying function of the lung and falling ill, because children's's shape gas does not fill, skin is weak, the diseases caused by exogenous pathogenic factor function is poor, children's's cold and heat are not known self-regulated in addition, are difficult to adapt to the variation of extraneous weather, thus winter, spring-QI wait changeable in, be the most easily that the heresy of six climate exopathogens is attacked.No matter heresy enters from mouth and nose, or from fur, enters, lung must stand in the breach, and causes a surname to fall not normal.At present, treat infantile acute bronchitis take western medicine as main, the clinical practice discovery, though the western medicine quick result, cure rate is low, and recurrent is high, side effect is large.

Summary of the invention

The purpose of this invention is to provide a kind of Chinese medicine composition for the treatment of infantile acute bronchitis.Infantile acute bronchitis is traditional Chinese medical science exogenous cough, and is sick due to affection of exogenous wind-cold or wind heat invasion and attack, strongly fragrant and heat-transformation mostly, and state of an illness aggravation, can breathe heavily change.Chinese traditional treatment is take the treatment lung as leading, reducing phlegm as auxiliary, take opening lung-energy, preventing phlegm from forming and stopping coughing as total Therapeutic Principle.

The objective of the invention is to be achieved through the following technical solutions, the Chinese medicine composition of this treatment infantile acute bronchitis is made by the Chinese medicine of following weight portion: Radix Crepidis Ligneae 9-11 part, Caulis Marsdeniae Tenacissimae 9-11 part, Radix Adenophorae Trachelioidis 8-10 part, Semen Sinapis Albae 5-7 part, Bulbus Fritillariae Thunbergii 5-7 part, Cortex Mori 8-10 part, Radix Adenophorae 6-8 part, Radix Platycodonis 6-8 part, Radix Glycyrrhizae 4-6 part.

Preferably, 10 parts of Radix Crepidis Ligneaes, 9 parts of 10 parts of, Radix Adenophorae Trachelioidis of Caulis Marsdeniae Tenacissimae, 6 parts of Semen Sinapis Albaes, 6 parts of Bulbus Fritillariae Thunbergiis, 9 parts of Cortex Mori, 7 parts of Radix Adenophoraes, 7 parts of Radix Platycodoniss, 5 parts, Radix Glycyrrhizae.

Preparation method is made decoction with above-mentioned Chinese medicine by traditional method.

In side: Radix Crepidis Ligneae: enter lung, liver two warps; Nourishing the lung to arrest cough, heat-clearing and toxic substances removing, help digestion and regulate the flow of vital energy; Control bronchitis, pneumonia.

Caulis Marsdeniae Tenacissimae: lung, Liver Channel; Heat-clearing and toxic substances removing, relieving cough and asthma; Control bronchitis.

Radix Adenophorae Trachelioidis: enter lung, spleen; Moistening the lung and resolving the phlegm, heat-clearing and toxic substances removing; The treatment acute bronchitis.

Semen Sinapis Albae: return lung meridian; Warming the lung to eliminate phlegm, promoting the circulation of QI eliminating stagnation, removing obstruction in the collateral to relieve pain.

Bulbus Fritillariae Thunbergii: return lung, heart channel; Removing heat-phlegm, the dissipating depression of QI eliminating stagnation.

Cortex Mori: return lung meridian; Eliminating pathogen from the lung for relieving asthma, inducing diuresis to remove edema.

Radix Adenophorae: return spleen, lung meridian; Clearing lung and nourishing yin, reinforcing stomach reg fluid.

Radix Platycodonis: enter lung meridian; Lung qi dispersing eliminates the phlegm, the sore-throat relieving evacuation of pus.

Radix Glycyrrhizae: GUIXIN, spleen, lung, stomach warp; Invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription.

Clinical data

The physical data 140 routine bronchitis infants of being admitted to hospital, male 72 examples wherein, female's 68 examples; Minimum 5 months of age, maximum 11 years old.Clinical symptoms is heating, cough, expectoration, asthma, and loss of appetite is slept not good enough etc.Have a medical check-up: pharyngeal hyperemia is obvious, and two pulmonary respiration sounds are thick, audible and rale sound and (or) sound of stridulating, 71 examples are taken the photograph the x-ray rabat, the two increased bronchovascular shadows of 34 illustrations, all meet the diagnostic criteria of acute bronchitis.Wherein 140 examples all have cough, expectoration, heating 127 examples, and asthma 20 examples, feel sick, vomiting 16 examples, is divided at random treatment group and matched group, two groups of severity extents, sex, equal no significant difference of age.

" Shanghai City traditional Chinese medical science disease conventional treatment " that diagnostic criteria is write according to Shanghai Health Bureau is as diagnostic criteria.The cough or with itching throat, diseases caused by exogenous pathogenic factor or endogenous cough have expectorant.Acute stage blood routine examination total white blood cells and neutrophilic granulocyte increase.Two lung auscultation audibles and respiratory murmur increase slightly, or with dried moist rale.Conducting lung X-ray examination is taken the photograph the sheet inspection normally or increased bronchovascular shadows.

The Therapeutic Method treatment group is taken Chinese medicine composition of the present invention, and potion, divided and took for three times every day, the oral xiao'er huatan zhike syrup of matched group, and each 5ml, three times on the one, two groups of homogeneous weeks are 1 course for the treatment of.

Criterion of therapeutical effect is observed body temperature variation and cough, expectoration, physical signs of lung is in the variation for the treatment of front and back and judge the drug effect standard.(1) recovery from illness: treated 7 days, body temperature is normal, the cough transference cure, and two lung rale sounds, the sound of stridulating disappears, and appetite is recovered; (2) produce effects: body temperature is normal, and the cough symptom obviously alleviates, and two lung rale sounds, the sound of stridulating obviously reduce, the front recovery of appetite; (3) effective: temperature decline, the cough sx↓, two lungs sounds reduce, but appetite is still poor; (4) invalid: the cardinal symptoms such as heating, cough surpass 3 days the course for the treatment of and without obviously improving, temperature decline＜1 ℃, aggravation or have other General Symptomies concurrently.

After (1) two group of therapeutic outcome controlled for two weeks, the transference cures statistics is in Table 1.

Table 1 transference cure statistics

(2) two groups all treat two courses for the treatment of after, curative effect statistics therapeutic outcome is in Table 2.

Table 2 statistics curative effect after liang two weeks of group treatment

As can be seen from Table 2, two groups of cure rates, total effective rates have significant difference (P＜0.5).

Untoward reaction appears in none routine infant of untoward reaction treatment group, and untoward reaction appears in matched group 11 examples, and wherein anaphylaxis appears in 3 routine infants, show as shiver with cold, high heat, give that dexamethasone is quiet postpones remission, 3 examples show as erythra, give chlorphenamine oral rear remission.

The specific embodiment

Embodiment one: take Radix Crepidis Ligneae 10g, Caulis Marsdeniae Tenacissimae 10g, Radix Adenophorae Trachelioidis 9g, Semen Sinapis Albae 6g, Bulbus Fritillariae Thunbergii 6g, Cortex Mori 9g, Radix Adenophorae 7g, Radix Platycodonis 7g, Radix Glycyrrhizae 5g.Decocting, potion, divided and took for three times every day, and a week is 1 course for the treatment of.

Embodiment two: take Radix Crepidis Ligneae 9g, Caulis Marsdeniae Tenacissimae 9g, Radix Adenophorae Trachelioidis 8g, Semen Sinapis Albae 5g, Bulbus Fritillariae Thunbergii 5g, Cortex Mori 8g, Radix Adenophorae 6g, Radix Platycodonis 6g, Radix Glycyrrhizae 4g.Decocting, potion, divided and took for three times every day, and a week is 1 course for the treatment of.

Embodiment three: take Radix Crepidis Ligneae 11g, Caulis Marsdeniae Tenacissimae 11g, Radix Adenophorae Trachelioidis 10g, Semen Sinapis Albae 7g, Bulbus Fritillariae Thunbergii 7g, Cortex Mori 10g, Radix Adenophorae 8g, Radix Platycodonis 8g, Radix Glycyrrhizae 6g.Decocting, potion, divided and took for three times every day, and a week is 1 course for the treatment of.

Claims

1. Chinese medicine composition for the treatment of infantile acute bronchitis, it is characterized in that this Chinese medicine composition made by the Chinese medicine of following weight portion: Radix Crepidis Ligneae 9-11 part, Caulis Marsdeniae Tenacissimae 9-11 part, Radix Adenophorae Trachelioidis 8-10 part, Semen Sinapis Albae 5-7 part, Bulbus Fritillariae Thunbergii 5-7 part, Cortex Mori 8-10 part, Radix Adenophorae 6-8 part, Radix Platycodonis 6-8 part, Radix Glycyrrhizae 4-6 part, make decoction by traditional method.

2. a kind of Chinese medicine composition for the treatment of infantile acute bronchitis according to claim 1, it is characterized in that this Chinese medicine composition made by the Chinese medicine of following weight portion: 10 parts of Radix Crepidis Ligneaes, 9 parts of 10 parts of, Radix Adenophorae Trachelioidis of Caulis Marsdeniae Tenacissimae, 6 parts of Semen Sinapis Albaes, 6 parts of Bulbus Fritillariae Thunbergiis, 9 parts of Cortex Mori, 7 parts of Radix Adenophoraes, 7 parts of Radix Platycodoniss, 5 parts, Radix Glycyrrhizae, make decoction by traditional method.