CN101595101A - 喹诺酮羧酸、其衍生物及它们的制备方法和作为抗菌剂的用途 - Google Patents
喹诺酮羧酸、其衍生物及它们的制备方法和作为抗菌剂的用途 Download PDFInfo
- Publication number
- CN101595101A CN101595101A CNA2008800031182A CN200880003118A CN101595101A CN 101595101 A CN101595101 A CN 101595101A CN A2008800031182 A CNA2008800031182 A CN A2008800031182A CN 200880003118 A CN200880003118 A CN 200880003118A CN 101595101 A CN101595101 A CN 101595101A
- Authority
- CN
- China
- Prior art keywords
- substituted
- unsubstituted
- formula
- compound
- fluoroquinolone
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
- C07D215/22—Oxygen atoms attached in position 2 or 4
- C07D215/233—Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Communicable Diseases (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Quinoline Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US11/626,397 US7632944B2 (en) | 2007-01-24 | 2007-01-24 | Quinolone carboxylic acids, derivatives thereof, and methods of making and using same |
| US11/626,397 | 2007-01-24 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN101595101A true CN101595101A (zh) | 2009-12-02 |
Family
ID=39410211
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNA2008800031182A Pending CN101595101A (zh) | 2007-01-24 | 2008-01-11 | 喹诺酮羧酸、其衍生物及它们的制备方法和作为抗菌剂的用途 |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US7632944B2 (https=) |
| EP (1) | EP2114915A2 (https=) |
| JP (1) | JP2010516775A (https=) |
| KR (1) | KR20090118027A (https=) |
| CN (1) | CN101595101A (https=) |
| AU (1) | AU2008209416B2 (https=) |
| BR (1) | BRPI0806581A2 (https=) |
| CA (2) | CA2674543C (https=) |
| MX (1) | MX2009007413A (https=) |
| WO (1) | WO2008091752A2 (https=) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9180817B2 (en) | 2010-01-25 | 2015-11-10 | Mci (Mirror Controls International) Netherlands B.V. | Exterior mirror unit, mirror support, method for assembly of an exterior mirror unit |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20090054406A1 (en) * | 2007-08-21 | 2009-02-26 | Ward Keith W | Compositions and Methods for Modulating Endophthalmitis Using Fluoroquinolones |
| US8415342B2 (en) * | 2008-10-29 | 2013-04-09 | Bausch & Lomb Incorporated | Besifloxacin ophthalmic composition for the treatment or control of infection |
| AU2009314072C1 (en) | 2008-11-15 | 2016-11-10 | Melinta Subsidiary Corp. | Antimicrobial compositions |
| US8481526B2 (en) * | 2009-03-25 | 2013-07-09 | Bausch & Lomb Incorporated | Fluoroquinolone carboxylic acid molecular crystals |
| US10167271B2 (en) | 2015-01-28 | 2019-01-01 | Mankind Pharma Ltd | Fluoroquinolone carboxylic acid compounds and use thereof for the preparation of besifloxacin hydrochloride |
| CN107880023B (zh) * | 2017-11-10 | 2021-02-19 | 西南大学 | 氟喹诺酮类胺基衍生物及其用途 |
| CN112159355B (zh) * | 2020-09-25 | 2022-06-24 | 西南大学 | 对氨基水杨酸氟喹诺酮类衍生物及其中间体、制备方法和应用 |
| CN112159354B (zh) * | 2020-09-25 | 2022-07-05 | 西南大学 | 对氨基水杨酸的氟喹诺酮类衍生物及其中间体、制备方法和应用 |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1086735A (en) * | 1977-11-03 | 1980-09-30 | John C. Danilewicz | Piperidino-quinazolines |
| EP0230946A3 (en) | 1986-01-20 | 1988-09-07 | Kyorin Pharmaceutical Co., Ltd. | Process for the preparation of quinolonecarboxylic acid derivatives |
| JPS63132885A (ja) | 1986-11-25 | 1988-06-04 | Hokuriku Seiyaku Co Ltd | キノリン−３−カルボン酸誘導体 |
| JPS63196580A (ja) | 1987-02-09 | 1988-08-15 | Hokuriku Seiyaku Co Ltd | キノリン−３−カルボン酸誘導体 |
| JPS63196579A (ja) | 1987-02-09 | 1988-08-15 | Hokuriku Seiyaku Co Ltd | キノリン−３−カルボン酸誘導体 |
| JP2613139B2 (ja) * | 1990-07-19 | 1997-05-21 | エスエス製薬 株式会社 | キノロンカルボン酸誘導体 |
| US5430028A (en) | 1992-05-26 | 1995-07-04 | Ss Pharmaceutical Co., Ltd. | 5-aminoquinolone carboxylic acid derivative and antibacterial agent containing the same as active ingredient |
| US5527910A (en) | 1992-12-30 | 1996-06-18 | Cheil Foods & Chemicals, Inc. | Pyridone carboxylic acid compounds and their uses for treating infectious diseases caused by bacteria |
| TW301607B (https=) * | 1993-03-09 | 1997-04-01 | Takeda Pharm Industry Co Ltd | |
| FR2706459B1 (fr) | 1993-06-17 | 1995-08-04 | Bouchara Sa | Nouveaux dérivés quinoloniques, leur procédé d'obtention et les compositions pharmaceutiques qui en contiennent. |
| SK33099A3 (en) * | 1996-09-13 | 2000-05-16 | Schering Corp | Novel tricyclic piperidinyl compounds useful as inhibitors of farnesyl-protein transferase |
| US6685958B2 (en) * | 2001-04-25 | 2004-02-03 | Insite Vision Incorporated | Quinolone carboxylic acid compositions and related methods of treatment |
| US6699492B2 (en) * | 1999-03-31 | 2004-03-02 | Insite Vision Incorporated | Quinolone carboxylic acid compositions and related methods of treatment |
| JP4612301B2 (ja) * | 2003-12-26 | 2011-01-12 | 広栄化学工業株式会社 | １−アルキル−４−アミノメチルピペリジンの製造法 |
| DE102004035203A1 (de) * | 2004-07-21 | 2006-02-16 | Bayer Healthcare Ag | Substituierte Chinolone |
-
2007
- 2007-01-24 US US11/626,397 patent/US7632944B2/en not_active Expired - Fee Related
-
2008
- 2008-01-11 KR KR1020097015534A patent/KR20090118027A/ko not_active Ceased
- 2008-01-11 CN CNA2008800031182A patent/CN101595101A/zh active Pending
- 2008-01-11 WO PCT/US2008/050865 patent/WO2008091752A2/en not_active Ceased
- 2008-01-11 BR BRPI0806581-0A patent/BRPI0806581A2/pt not_active IP Right Cessation
- 2008-01-11 EP EP08705887A patent/EP2114915A2/en not_active Withdrawn
- 2008-01-11 CA CA2674543A patent/CA2674543C/en not_active Expired - Fee Related
- 2008-01-11 JP JP2009547352A patent/JP2010516775A/ja active Pending
- 2008-01-11 MX MX2009007413A patent/MX2009007413A/es active IP Right Grant
- 2008-01-11 CA CA2790690A patent/CA2790690A1/en not_active Abandoned
- 2008-01-11 AU AU2008209416A patent/AU2008209416B2/en not_active Ceased
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9180817B2 (en) | 2010-01-25 | 2015-11-10 | Mci (Mirror Controls International) Netherlands B.V. | Exterior mirror unit, mirror support, method for assembly of an exterior mirror unit |
Also Published As
| Publication number | Publication date |
|---|---|
| AU2008209416B2 (en) | 2013-05-09 |
| US20080176834A1 (en) | 2008-07-24 |
| WO2008091752A2 (en) | 2008-07-31 |
| CA2674543A1 (en) | 2008-07-31 |
| BRPI0806581A2 (pt) | 2014-05-06 |
| WO2008091752A3 (en) | 2008-10-16 |
| EP2114915A2 (en) | 2009-11-11 |
| US7632944B2 (en) | 2009-12-15 |
| MX2009007413A (es) | 2009-07-17 |
| KR20090118027A (ko) | 2009-11-17 |
| JP2010516775A (ja) | 2010-05-20 |
| AU2008209416A1 (en) | 2008-07-31 |
| CA2790690A1 (en) | 2008-07-31 |
| CA2674543C (en) | 2012-12-04 |
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| US7868021B2 (en) | Antimicrobial quinolones, their compositions and uses | |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C02 | Deemed withdrawal of patent application after publication (patent law 2001) | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20091202 |