CN101568343A - 用于治疗癌症的方法 - Google Patents

用于治疗癌症的方法 Download PDF

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Publication number
CN101568343A
CN101568343A CNA200780027591XA CN200780027591A CN101568343A CN 101568343 A CN101568343 A CN 101568343A CN A200780027591X A CNA200780027591X A CN A200780027591XA CN 200780027591 A CN200780027591 A CN 200780027591A CN 101568343 A CN101568343 A CN 101568343A
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CN
China
Prior art keywords
pharmaceutically acceptable
derivant
acceptable salt
cancer
tylosin
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Pending
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CNA200780027591XA
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English (en)
Chinese (zh)
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莉娜·罗西娜巴斯菲尔德
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Ramot at Tel Aviv University Ltd
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Ramot at Tel Aviv University Ltd
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Publication of CN101568343A publication Critical patent/CN101568343A/zh
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
CNA200780027591XA 2006-06-12 2007-06-12 用于治疗癌症的方法 Pending CN101568343A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US81260506P 2006-06-12 2006-06-12
US60/812,605 2006-06-12

Publications (1)

Publication Number Publication Date
CN101568343A true CN101568343A (zh) 2009-10-28

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ID=38541966

Family Applications (1)

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CNA200780027591XA Pending CN101568343A (zh) 2006-06-12 2007-06-12 用于治疗癌症的方法

Country Status (7)

Country Link
US (1) US9486467B2 (enExample)
EP (1) EP2029147B1 (enExample)
JP (1) JP2009539970A (enExample)
CN (1) CN101568343A (enExample)
AT (1) ATE468119T1 (enExample)
DE (1) DE602007006663D1 (enExample)
WO (1) WO2007144876A1 (enExample)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2019007368A1 (zh) * 2017-07-04 2019-01-10 沈阳福洋医药科技有限公司 异戊酰螺旋霉素i、ii和/或iii在制备治疗和/或预防肿瘤药物方面的应用和药物
WO2019141254A1 (zh) * 2018-01-19 2019-07-25 沈阳福洋医药科技有限公司 一种mTOR抑制剂、药物组合物及其应用
CN110545820A (zh) * 2017-04-06 2019-12-06 沈阳福洋医药科技有限公司 可利霉素及其药学上可接受的盐在制备治疗和/或预防肿瘤药物方面的应用
CN110709408A (zh) * 2017-02-22 2020-01-17 免疫系统调节控股有限公司 新型免疫刺激大环内酯
US11413302B2 (en) 2018-01-19 2022-08-16 Shenyang Fuyang Pharmaceutical Technology Co., Ltd. Use of carrimycin or active ingredients thereof and use thereof

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EA201500699A1 (ru) 2012-12-24 2015-12-30 Рамот Эт Тель-Авив Юниверсити Лтд. Агенты для лечения генетических заболеваний, возникающих в результате нонсенс-мутаций, и способы идентификации этих агентов
WO2015198329A1 (en) 2014-06-25 2015-12-30 Bio Blast Pharma Ltd. Injectable formulations for intrathecal administration of antibiotic agents
US11351185B2 (en) 2020-03-11 2022-06-07 Asclea Corporation Use of isovalerylspiramycins as anti-cancer agents to inhibit metastasis
WO2023283427A2 (en) * 2021-07-09 2023-01-12 Verdure Biotech, Inc. Enteric and delayed release formulations of locally bioavailable drugs (lbd) targeting the colon
US20240410019A1 (en) * 2021-12-14 2024-12-12 The Regents Of The University Of California Clustered mutations for the treatment of cancer

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH619267A5 (enExample) 1975-08-01 1980-09-15 Sanraku Ocean Co
GB1540397A (en) 1976-12-08 1979-02-14 May & Baker Ltd Spiramycin esters
US4064143A (en) 1976-12-10 1977-12-20 Pfizer Inc. Oleandomycin derivatives
US4205163A (en) 1977-11-08 1980-05-27 Sanraku-Ocean Co., Ltd. Tylosin derivatives
US4124755A (en) 1978-01-03 1978-11-07 Pfizer Inc. 11-Alkanoyl-4"-deoxy-4"-isonitrilo-oleandomycin derivatives
SE445739B (sv) 1978-09-14 1986-07-14 Toyo Jozo Kk 3", 4"-diacyltylosinderivat
US4429116A (en) 1982-12-27 1984-01-31 Pfizer Inc. Alkylated oleandomycin containing compounds
US5872103A (en) * 1986-11-26 1999-02-16 Belletti; Dino A. Prevention of mammary tumors by treatment with cardiac glycosides
US5324720A (en) 1992-03-20 1994-06-28 Merck & Co., Inc. Methods of achieving antitumor activity using 16-membered-macrolide-type compounds
CA2127578A1 (en) 1993-07-08 1995-01-09 Keiichi Ajito 16-membered macrolide derivatives and process for producing the same
CA2259936C (en) * 1996-07-08 2009-02-03 Magnus Pfahl Apoptosis inducing adamantyl derivatives and their usage as anti-cancer agents
AP1060A (en) 1998-01-02 2002-04-23 Pfizer Prod Inc Novel erythromycin derivatives.
HRP980646B1 (en) 1998-12-30 2008-02-29 GlaxoSmithKline istra�iva�ki centar Zagreb d.o.o. Novel oleandomycin derivatives
IL133077A0 (en) * 1999-01-29 2001-03-19 Pfizer Prod Inc Azithromycin combination for emesis control in dogs
OA11945A (en) 1999-05-24 2006-04-13 Pfizer Prod Inc 13-Methyl erythromycin derivatives.
US6455680B1 (en) 2000-12-21 2002-09-24 Abbott Laboratories Methods utilizing aryl thioimines in synthesis of erythromycin derivatives
US20050171032A1 (en) 2002-04-11 2005-08-04 Children's Medical Center Corporation Methods for the treatment of cancer
CN1562066A (zh) 2004-04-14 2005-01-12 山东鲁抗舍里乐药业有限公司 酒石酸泰乐菌素颗粒剂及其制备方法
GB0417852D0 (en) * 2004-08-11 2004-09-15 Biotica Tech Ltd Production of polyketides and other natural products

Cited By (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110709408A (zh) * 2017-02-22 2020-01-17 免疫系统调节控股有限公司 新型免疫刺激大环内酯
CN110709408B (zh) * 2017-02-22 2022-10-25 Isr免疫系统调节控股公共有限公司 新型免疫刺激大环内酯
CN110545820A (zh) * 2017-04-06 2019-12-06 沈阳福洋医药科技有限公司 可利霉素及其药学上可接受的盐在制备治疗和/或预防肿瘤药物方面的应用
CN110545820B (zh) * 2017-04-06 2023-01-10 沈阳福洋医药科技有限公司 可利霉素及其药学上可接受的盐在制备治疗和/或预防肿瘤药物方面的应用
WO2019007368A1 (zh) * 2017-07-04 2019-01-10 沈阳福洋医药科技有限公司 异戊酰螺旋霉素i、ii和/或iii在制备治疗和/或预防肿瘤药物方面的应用和药物
CN110869027A (zh) * 2017-07-04 2020-03-06 沈阳福洋医药科技有限公司 异戊酰螺旋霉素i、ii和/或iii在制备治疗和/或预防肿瘤药物方面的应用和药物
RU2766176C2 (ru) * 2017-07-04 2022-02-08 Шенянг Фуянг Фармасьютекал Технолоджи Ко., Лтд. Применение изовалерил-спирамицина i, ii и/или iii при изготовлении препарата для лечения и/или профилактики опухоли и получения лекарственного препарата
CN110869027B (zh) * 2017-07-04 2023-09-08 沈阳福洋医药科技有限公司 异戊酰螺旋霉素i、ii和/或iii在制备治疗和/或预防肿瘤药物方面的应用和药物
WO2019141254A1 (zh) * 2018-01-19 2019-07-25 沈阳福洋医药科技有限公司 一种mTOR抑制剂、药物组合物及其应用
CN110051845A (zh) * 2018-01-19 2019-07-26 沈阳福洋医药科技有限公司 一种mTOR抑制剂、药物组合物及其应用
US11413302B2 (en) 2018-01-19 2022-08-16 Shenyang Fuyang Pharmaceutical Technology Co., Ltd. Use of carrimycin or active ingredients thereof and use thereof

Also Published As

Publication number Publication date
EP2029147B1 (en) 2010-05-19
EP2029147A1 (en) 2009-03-04
JP2009539970A (ja) 2009-11-19
US9486467B2 (en) 2016-11-08
ATE468119T1 (de) 2010-06-15
WO2007144876A1 (en) 2007-12-21
US20110306571A1 (en) 2011-12-15
DE602007006663D1 (de) 2010-07-01

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Application publication date: 20091028