CN101554413A - Veterinary drug granule for preventing and curing avian colibacillosis and preparation method thereof - Google Patents
Veterinary drug granule for preventing and curing avian colibacillosis and preparation method thereof Download PDFInfo
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- CN101554413A CN101554413A CNA2008100527014A CN200810052701A CN101554413A CN 101554413 A CN101554413 A CN 101554413A CN A2008100527014 A CNA2008100527014 A CN A2008100527014A CN 200810052701 A CN200810052701 A CN 200810052701A CN 101554413 A CN101554413 A CN 101554413A
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Abstract
The invention relates to a vterinary drug granule for preventing and curing avian colibacillosis and a preparation method thereof, and the vterinary drug granule is characterized by comprising the following medicaments by weight portions: 1 to 3 portions of rhizoma coptidis, 1 to 6 portions of rhubarb and 1 to 4 portions of bikal skullcap root. The invention has the advantages of solving the problem of drug residues which exist in the existing antibacterials and being able to satisfy the people's growing needs for producing green pollution-free animal products. The drug is a pure veterinary drug, does not have drug residues, and does not have toxic side effect to organism.
Description
Technical field
The invention belongs to fowl and use the herbal medicine granule, relate in particular to a kind of herbal medicine granule of preventing and treating avian colibacillosis and preparation method thereof.
Background technology
Avian colibacillosis is to cause a kind of common infectious disease by bacillus coli.Comprising multiple sick type, is to endanger one of most important bacterial disease of aviculture at present.Though a lot of antibacterials have certain curative effect to primary disease, but escherichia coli are easy to produce drug resistance to antibacterials, the curative effect of medicine is descended gradually, in this case, the use amount that people often take to strengthen antibacterials improves the curative effect of medicine, and the disastrous effect brought of way is like this: cause antibacterial that the drug resistance of antibacterials is further strengthened; Medicine is in the intravital residual further increase of machine; It is bigger that the drug intoxication probability takes place in colony.Along with people improve constantly the requirement of environmental protection animal products and the Ministry of Agriculture bans use of some chemical drugss to be used for the control of livestock and poultry.Aquaculture demands developing the Chinese medicine preparation of beastly avian disease urgently.
Summary of the invention
The present invention is in order to overcome deficiency of the prior art, provides a kind of and does not have any drug residue, to herbal medicine granule of body control avian colibacillosis without any side effects and preparation method thereof.
The present invention is achieved through the following technical solutions for achieving the above object: a kind of herbal medicine granule of preventing and treating avian colibacillosis is characterized in that: form by following medicine, count by weight,
1～3 part of Rhizoma Coptidis, 1～6 part of Radix Et Rhizoma Rhei, 1～4 part of Radix Scutellariae.
The preferred composition of the herbal medicine granule of described control avian colibacillosis is: counts by weight,
1 part of Rhizoma Coptidis, 3 parts of Radix Et Rhizoma Rhei, 1.5 parts of Radix Scutellariaes.
A kind of herbal medicine process for producing granula of preventing and treating avian colibacillosis is characterized in that: carry out as follows:
(1) takes by weighing 1～3 part of Rhizoma Coptidis, 1～6 part of Radix Et Rhizoma Rhei, Radix Scutellariae by weight and be raw material for 1～4 part.
(2) above-mentioned Chinese medicine is decocted with water twice, the 1 time respectively and decocted 1.5 hours, the 2nd decoction 1 hour merges twice decoction liquor, filters, and filtrate is concentrated into relative density and is about 1.25 clear paste, is spray dried to dry extract; Above-mentioned 3 kinds of dry extracts are merged, add suitable amount of sucrose and dextrin, mixing is made granule, 75 ℃ of dryings, promptly.
Composition principle of the present invention: according to the property of Rhizoma Coptidis, Radix Et Rhizoma Rhei, the various Chinese medicines of Radix Scutellariae, distinguish the flavor of, return, through, function cures mainly and traditional Chinese veterinary medicine to the principle of the determination of treatment based on pathogenesis obtained through differentiation of symptoms and signs of fowl coliform disease.Chinese veterinarian thinks that avian colibacillosis is to invade in the epidemic disease poison, exuberant lung-stomach heat, and the blood stasis stagnation of QI is controlled suitable heat-clearing and toxic substances removing, activating blood circulation to dissipate blood stasis.
Described Chinese medicine all meets " Chinese veterinary drug allusion quotation " version two ministerial standards in 2005.
The property of medicine of each Chinese medicine of distinguishing the flavor of and main effect:
Rhizoma Coptidis: hardship, cold.GUIXIN, spleen, stomach, liver, gallbladder, large intestine channel.Function: heat clearing and damp drying, eliminating fire and detoxication.Cure mainly: diseases such as damp-heat dysentery, excessive heat of liver and gallbladder.
Radix Scutellariae: hardship, cold.Return lung, gallbladder, spleen, large intestine, small intestine meridian.Function: heat clearing and damp drying, eliminating fire and detoxication.Cure mainly: gastrointestinal is damp and hot, diseases such as dysentery.
Radix Et Rhizoma Rhei: hardship, cold.Return spleen, stomach, large intestine, liver, pericardium channel.Function: purging heat and dredging bowels, removing pathogenic heat from blood and toxic substance from the body etc.Cure mainly: damp and hot constipation, diseases such as enteritis.
Beneficial effect of the present invention: overcome the drug residue problem that existing antibacterials exist, can satisfy the growing production green non-pollution animal products demand of people.This medicine is pure herbal medicine preparation, so no any drug residue, without any side effects to body.
The specific embodiment
Below in conjunction with preferred embodiment, to details are as follows according to the specific embodiment provided by the invention:
Embodiment 1
A kind of herbal medicine granule of preventing and treating avian colibacillosis, preferred ingredient, weight is formulated by every part of 100g:
Rhizoma Coptidis 100g, Radix Et Rhizoma Rhei 300g, Radix Scutellariae 150g.
The preparation method of the herbal medicine granule of control avian colibacillosis, carry out as follows:
(1) gets Rhizoma Coptidis 100g, Radix Et Rhizoma Rhei 300g, Radix Scutellariae 150g.
(2) Rhizoma Coptidis is added water 1000g, decocted 1.5 hours, filter, filtering residue adds water 500g, decocts 1 hour, and filtration merges 2 times decoction liquor, and it is 1.25 clear paste that filtrate is concentrated into relative density, is spray dried to dry extract.
(3) Radix Et Rhizoma Rhei is added water 1500g, decocted 1.5 hours, filter, filtering residue adds water 1000g, decocts 1 hour, and filtration merges 2 times decoction liquor, and it is 1.25 clear paste that filtrate is concentrated into relative density, is spray dried to dry extract.
(4) Radix Scutellariae is added water 750g, decocted 1.5 hours, filter, filtering residue adds water 500g, decocts 1 hour, and filtration merges 2 times decoction liquor, and it is 1.25 clear paste that filtrate is concentrated into relative density, is spray dried to dry extract.
(5) above-mentioned 3 kinds of dry extracts are merged, add sucrose and the 150g dextrin of 850g, mixing is made granule, 75 ℃ of dryings, promptly.
Embodiment 2
A kind of herbal medicine granule of preventing and treating avian colibacillosis, by following component, weight is formulated by every part of 100g:
Rhizoma Coptidis 160g, Radix Et Rhizoma Rhei 500g, Radix Scutellariae 250g.
The preparation method of the herbal medicine granule of control avian colibacillosis, carry out as follows:
(1) gets Rhizoma Coptidis 160g, Radix Et Rhizoma Rhei 500g, Radix Scutellariae 250g.
(2) Rhizoma Coptidis is added water 1000g, decocted 1.5 hours, filter, filtering residue adds water 500g, decocts 1 hour, and filtration merges 2 times decoction liquor, and it is 1.25 clear paste that filtrate is concentrated into relative density, is spray dried to dry extract.
(3) Radix Et Rhizoma Rhei is added water 1500g, decocted 1.5 hours, filter, filtering residue adds water 1000g, decocts 1 hour, and filtration merges 2 times decoction liquor, and it is 1.25 clear paste that filtrate is concentrated into relative density, is spray dried to dry extract.
(4) Radix Scutellariae is added water 750g, decocted 1.5 hours, filter, filtering residue adds water 500g, decocts 1 hour, and filtration merges 2 times decoction liquor, and it is 1.25 clear paste that filtrate is concentrated into relative density, is spray dried to dry extract.
(5) above-mentioned 3 kinds of dry extracts are merged, add sucrose and the 150g dextrin of 850g, mixing is made granule, 75 ℃ of dryings, promptly.
Embodiment 3
A kind of herbal medicine granule of preventing and treating avian colibacillosis, by following component, weight is formulated by every part of 100g:
Rhizoma Coptidis 100g, Radix Et Rhizoma Rhei 600g, Radix Scutellariae 400g.
The preparation method of the herbal medicine granule of control avian colibacillosis, carry out as follows:
(1) gets Rhizoma Coptidis 100g, Radix Et Rhizoma Rhei 600g, Radix Scutellariae 400g.
(2) Rhizoma Coptidis is added water 1200g, decocted 1.5 hours, filter, filtering residue adds water 600g, decocts 1 hour, and filtration merges 2 times decoction liquor, and it is 1.25 clear paste that filtrate is concentrated into relative density, is spray dried to dry extract.
(3) Radix Et Rhizoma Rhei is added water 1500g, decocted 1.5 hours, filter, filtering residue adds water 800g, decocts 1 hour, and filtration merges 2 times decoction liquor, and it is 1.25 clear paste that filtrate is concentrated into relative density, is spray dried to dry extract.
(4) Radix Scutellariae is added water 1500g, decocted 1.5 hours, filter, filtering residue adds water 750g, decocts 1 hour, and filtration merges 2 times decoction liquor, and it is 1.25 clear paste that filtrate is concentrated into relative density, is spray dried to dry extract.
(5) above-mentioned 3 kinds of dry extracts are merged, add sucrose and the 300g dextrin of 500g, mixing is made granule, 75 ℃ of dryings, promptly.
Embodiment 4
A kind of herbal medicine granule of preventing and treating avian colibacillosis, following component, weight is formulated by every part of 100g: Rhizoma Coptidis 300g, Radix Et Rhizoma Rhei 100g, Radix Scutellariae 100g.
The preparation method of the herbal medicine granule of control avian colibacillosis, carry out as follows:
(1) gets Rhizoma Coptidis 300g, Radix Et Rhizoma Rhei 100g, Radix Scutellariae 100g.
(2) Rhizoma Coptidis is added water 500g, decocted 1.5 hours, filter, filtering residue adds water 250g, decocts 1 hour, and filtration merges 2 times decoction liquor, and it is 1.25 clear paste that filtrate is concentrated into relative density, is spray dried to dry extract.
(3) Radix Et Rhizoma Rhei is added water 1300g, decocted 1.5 hours, filter, filtering residue adds water 700g, decocts 1 hour, and filtration merges 2 times decoction liquor, and it is 1.25 clear paste that filtrate is concentrated into relative density, is spray dried to dry extract.
(4) Radix Scutellariae is added water 750g, decocted 1.5 hours, filter, filtering residue adds water 400g, decocts 1 hour, and filtration merges 2 times decoction liquor, and it is 1.25 clear paste that filtrate is concentrated into relative density, is spray dried to dry extract.
(5) above-mentioned 3 kinds of dry extracts are merged, add sucrose and the 200g dextrin of 300g, mixing is made granule, 75 ℃ of dryings, promptly.
Clinical trial:
Medicine of the present invention is pressed the dosage of 1g/kg body weight, with hot water this product is washed open earlier, and then added an amount of drinking-water, freely drink for poultry.
For example: Jinghai County plant raises table hens 5000, when raising to 28 ages in days, takes place with row's yellow-white loose stool, cuts open the inspection pathological change and is: pericarditis, perihepatitis, intestinal hyperemia, hemorrhagely be the disease of feature.Through the laboratory separation of bacterial with do Bacteria Identification and be diagnosed as avian colibacillosis.Satisfy with herbal medicine granule of the present invention and press above-mentioned dosage treatment, medication after 5 days the state of an illness controlled.
The above only is preferred embodiment of the present invention, is not structure of the present invention is done any pro forma restriction.Every foundation technical spirit of the present invention all still belongs in the scope of technical scheme of the present invention any simple modification, equivalent variations and modification that above embodiment did.
Claims (3)
1, a kind of herbal medicine granule of preventing and treating avian colibacillosis is characterized in that: form meter by weight by following medicine,
1～3 part of Rhizoma Coptidis, 1～6 part of Radix Et Rhizoma Rhei, 1～4 part of Radix Scutellariae.
2, the herbal medicine granule of control avian colibacillosis according to claim 1, it is characterized in that: it is preferably formed, and counts 1 part of Rhizoma Coptidis, 3 parts of Radix Et Rhizoma Rhei, 1.5 parts of Radix Scutellariaes by weight.
3, the herbal medicine process for producing granula of above-mentioned control avian colibacillosis is characterized in that: carry out as follows:
(1) takes by weighing 1～3 part of Rhizoma Coptidis, 1～6 part of Radix Et Rhizoma Rhei, Radix Scutellariae by weight and be raw material for 1～4 part.
(2) above-mentioned Chinese medicine is decocted with water twice, the 1 time respectively and decocted 1.5 hours, the 2nd decoction 1 hour merges twice decoction liquor, filters, and filtrate is concentrated into relative density and is about 1.25 clear paste, is spray dried to dry extract; Above-mentioned 3 kinds of dry extracts are merged, add suitable amount of sucrose and dextrin, mixing is made granule, 75 ℃ of dryings, promptly.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNA2008100527014A CN101554413A (en) | 2008-04-11 | 2008-04-11 | Veterinary drug granule for preventing and curing avian colibacillosis and preparation method thereof |
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| Application Number | Priority Date | Filing Date | Title |
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| CNA2008100527014A CN101554413A (en) | 2008-04-11 | 2008-04-11 | Veterinary drug granule for preventing and curing avian colibacillosis and preparation method thereof |
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| CN101554413A true CN101554413A (en) | 2009-10-14 |
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| CNA2008100527014A Pending CN101554413A (en) | 2008-04-11 | 2008-04-11 | Veterinary drug granule for preventing and curing avian colibacillosis and preparation method thereof |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102908409A (en) * | 2012-11-15 | 2013-02-06 | 成都乾坤动物药业有限公司 | Production process of Chinese rhubarb fine powder granules |
| CN104758391A (en) * | 2015-04-03 | 2015-07-08 | 贵州省畜牧兽医研究所 | Diarrhea-stopping traditional Chinese compound preparation for animals and preparation method of diarrhea-stopping traditional Chinese compound preparation |
| CN106692337A (en) * | 2016-12-16 | 2017-05-24 | 中科植源康（北京）医学研究所有限公司 | Chinese herbal medicine composition for improving animal palatability and preparation method and application thereof in replacing antibiotic, and pig feed composition |
-
2008
- 2008-04-11 CN CNA2008100527014A patent/CN101554413A/en active Pending
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102908409A (en) * | 2012-11-15 | 2013-02-06 | 成都乾坤动物药业有限公司 | Production process of Chinese rhubarb fine powder granules |
| CN104758391A (en) * | 2015-04-03 | 2015-07-08 | 贵州省畜牧兽医研究所 | Diarrhea-stopping traditional Chinese compound preparation for animals and preparation method of diarrhea-stopping traditional Chinese compound preparation |
| CN104758391B (en) * | 2015-04-03 | 2017-11-24 | 贵州省畜牧兽医研究所 | Stop dysentery compound Chinese medicinal preparation and its production method for animals |
| CN106692337A (en) * | 2016-12-16 | 2017-05-24 | 中科植源康（北京）医学研究所有限公司 | Chinese herbal medicine composition for improving animal palatability and preparation method and application thereof in replacing antibiotic, and pig feed composition |
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Open date: 20091014 |