CN101543659A - 单独的普罗布考或与西罗莫司联合的局部血管给药系统 - Google Patents

单独的普罗布考或与西罗莫司联合的局部血管给药系统 Download PDF

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Publication number
CN101543659A
CN101543659A CN200810127395A CN200810127395A CN101543659A CN 101543659 A CN101543659 A CN 101543659A CN 200810127395 A CN200810127395 A CN 200810127395A CN 200810127395 A CN200810127395 A CN 200810127395A CN 101543659 A CN101543659 A CN 101543659A
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coating
rapamycin
medical treatment
treatment device
support
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CN200810127395A
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Chinese (zh)
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R·法洛蒂科
J·Z·赵
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Cordis Corp
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Cordis Corp
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Application filed by Cordis Corp filed Critical Cordis Corp
Publication of CN101543659A publication Critical patent/CN101543659A/zh
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L31/16—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/28—Materials for coating prostheses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/40—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/08—Materials for coatings
    • A61L31/10—Macromolecular materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/416—Anti-neoplastic or anti-proliferative or anti-restenosis or anti-angiogenic agents, e.g. paclitaxel, sirolimus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/45—Mixtures of two or more drugs, e.g. synergistic mixtures

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Vascular Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medicinal Chemistry (AREA)
  • Surgery (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Dermatology (AREA)
  • Transplantation (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Diabetes (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Composite Materials (AREA)
  • Materials Engineering (AREA)
  • Materials For Medical Uses (AREA)
  • Media Introduction/Drainage Providing Device (AREA)
  • Prostheses (AREA)
  • Surgical Instruments (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CN200810127395A 2007-03-28 2008-03-28 单独的普罗布考或与西罗莫司联合的局部血管给药系统 Pending CN101543659A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11/692744 2007-03-28
US11/692,744 US20080241215A1 (en) 2007-03-28 2007-03-28 Local vascular delivery of probucol alone or in combination with sirolimus to treat restenosis, vulnerable plaque, aaa and stroke

Publications (1)

Publication Number Publication Date
CN101543659A true CN101543659A (zh) 2009-09-30

Family

ID=39642698

Family Applications (1)

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CN200810127395A Pending CN101543659A (zh) 2007-03-28 2008-03-28 单独的普罗布考或与西罗莫司联合的局部血管给药系统

Country Status (10)

Country Link
US (1) US20080241215A1 (enExample)
EP (1) EP1974758A3 (enExample)
JP (1) JP5398996B2 (enExample)
KR (1) KR101678369B1 (enExample)
CN (1) CN101543659A (enExample)
AU (1) AU2008201396B2 (enExample)
BR (1) BRPI0803738A2 (enExample)
IL (3) IL190383A0 (enExample)
MX (1) MX2008004317A (enExample)
RU (1) RU2481084C2 (enExample)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101953721A (zh) * 2010-10-28 2011-01-26 东华大学 具有形状记忆功能的多层复合人造血管膜及其制备方法
CN107296992A (zh) * 2017-06-13 2017-10-27 中国人民解放军总医院第附属医院 血管对接装置及包括该装置的血管伤救治装置
CN116392648A (zh) * 2023-04-14 2023-07-07 中国科学院长春应用化学研究所 一种温度、炎症双响应性的抗凝复合涂层及其制备方法、应用
WO2024222834A1 (zh) * 2023-04-27 2024-10-31 北京信立泰医疗器械有限公司 药物涂层及含有其的医疗装置、系统和制备方法

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10076641B2 (en) 2005-05-11 2018-09-18 The Spectranetics Corporation Methods and systems for delivering substances into luminal walls
US20090155337A1 (en) * 2007-11-12 2009-06-18 Endologix, Inc. Method and agent for in-situ stabilization of vascular tissue
CN101474455B (zh) 2009-01-19 2012-07-25 北京天地和协科技有限公司 一种储存和释放多种药物的纳米级微孔结构药物洗脱器械及制备方法
US20100280600A1 (en) * 2009-04-30 2010-11-04 Vipul Bhupendra Dave Dual drug stent
EP2380604A1 (en) 2010-04-19 2011-10-26 InnoRa Gmbh Improved coating formulations for scoring or cutting balloon catheters
EP2380605A1 (en) 2010-04-19 2011-10-26 InnoRa Gmbh Improved formulations for drug-coated medical devices
EP2383000A1 (en) 2010-04-19 2011-11-02 InnoRa Gmbh Limus-coated medical devices
US9415140B2 (en) 2011-10-14 2016-08-16 Innora Gmbh Formulations for drug-coated medical devices
US20180122351A1 (en) * 2016-10-31 2018-05-03 Garmin Switzerland Gmbh Transducer mounting device
US11622873B2 (en) * 2017-03-06 2023-04-11 Dyverto Ag Multilayer luminal endoprosthesis assembly and manufacturing method
US11654036B2 (en) 2020-05-26 2023-05-23 Elixir Medical Corporation Anticoagulant compounds and methods and devices for their use
JP2023527328A (ja) * 2020-05-26 2023-06-28 エリクシアー メディカル コーポレイション 抗凝固化合物ならびにその使用のための方法およびデバイス
US12310837B1 (en) 2024-01-22 2025-05-27 Taurus Vascular, Inc. Methods and systems for transcaval treatment of aneurysms
US12318563B1 (en) 2021-02-02 2025-06-03 Taurus Vascular, Inc. Methods and systems for transcaval treatment of aneurysms
WO2024030418A2 (en) * 2022-08-02 2024-02-08 The Secant Group, Llc Biodegradable, elastomeric anastomotic tissue junction stabilizer
WO2024155994A1 (en) * 2023-01-20 2024-07-25 Texas Medical Center Methods and systems for transcaval treatment of aneurysms

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030060877A1 (en) * 2001-09-25 2003-03-27 Robert Falotico Coated medical devices for the treatment of vascular disease
CN1568166A (zh) * 2001-10-15 2005-01-19 荷姆泰克股份有限公司 预防再狭窄的涂层支架
CN1672745A (zh) * 2004-03-22 2005-09-28 科迪斯公司 局部血管递送依托泊苷与雷帕霉素的组合以防止血管损伤后的再狭窄

Family Cites Families (70)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR901228A (fr) 1943-01-16 1945-07-20 Deutsche Edelstahlwerke Ag Système d'aimant à entrefer annulaire
US3862332A (en) * 1967-05-11 1975-01-21 Dow Chemical Co Method of lowering serum cholesterol
US3576886A (en) * 1968-03-22 1971-04-27 Atlantic Richfield Co Isomerization of medium ring cyclic alphatic epoxides
US3576883A (en) 1969-06-30 1971-04-27 Consolidation Coal Co Alkylidenedithiobisphenols
ZA737247B (en) * 1972-09-29 1975-04-30 Ayerst Mckenna & Harrison Rapamycin and process of preparation
US3959078A (en) * 1973-05-18 1976-05-25 Midwest Research Institute Enzyme immobilization with a thermochemical-photochemical bifunctional agent
SU1088712A1 (ru) * 1979-11-14 1984-04-30 Всесоюзный научно-исследовательский и испытательный институт медицинской техники Аппарат дл циркул рного сшивани кровеносных сосудов
US4366819A (en) * 1980-11-17 1983-01-04 Kaster Robert L Anastomotic fitting
US4368736A (en) * 1980-11-17 1983-01-18 Kaster Robert L Anastomotic fitting
US4917091A (en) * 1982-06-24 1990-04-17 Unilink Ab Annular fastening means
SE431609B (sv) * 1982-06-24 1984-02-20 Unilink Ab Kirurgiskt instrument for astadkommande av anastomos och festelement herfor
US4722906A (en) * 1982-09-29 1988-02-02 Bio-Metric Systems, Inc. Binding reagents and methods
US4733665C2 (en) * 1985-11-07 2002-01-29 Expandable Grafts Partnership Expandable intraluminal graft and method and apparatus for implanting an expandable intraluminal graft
FR2601675B1 (fr) * 1986-07-17 1988-09-23 Rhone Poulenc Sante Derives du taxol, leur preparation et les compositions pharmaceutiques qui les contiennent
FR2601676B1 (fr) * 1986-07-17 1988-09-23 Rhone Poulenc Sante Procede de preparation du taxol et du desacetyl-10 taxol
US4942184A (en) * 1988-03-07 1990-07-17 The United States Of America As Represented By The Department Of Health And Human Services Water soluble, antineoplastic derivatives of taxol
JPH02177784A (ja) * 1988-12-28 1990-07-10 Canon Inc 画像信号記録方法
US4917070A (en) * 1989-02-21 1990-04-17 Quarters Industries, Inc. Cable guide assembly for a compound bow
US5234447A (en) * 1990-08-28 1993-08-10 Robert L. Kaster Side-to-end vascular anastomotic staple apparatus
US5278324A (en) * 1990-08-28 1994-01-11 Virginia Tech Intellectual Properties, Inc. Water soluble derivatives of taxol
US5059699A (en) * 1990-08-28 1991-10-22 Virginia Tech Intellectual Properties, Inc. Water soluble derivatives of taxol
TW197439B (enExample) * 1991-04-04 1993-01-01 Ueno Pharmaceutics Applic Res Co Ltd
CA2071160A1 (en) * 1991-07-31 1993-02-01 Vittorio Farina Asymmetric synthesis of taxol side chain
SG46582A1 (en) * 1991-09-23 1998-02-20 Univ Florida State 10-Desacetoxytaxol derivatives
US5283253A (en) * 1991-09-23 1994-02-01 Florida State University Furyl or thienyl carbonyl substituted taxanes and pharmaceutical compositions containing them
US5272171A (en) * 1992-02-13 1993-12-21 Bristol-Myers Squibb Company Phosphonooxy and carbonate derivatives of taxol
US5200534A (en) * 1992-03-13 1993-04-06 University Of Florida Process for the preparation of taxol and 10-deacetyltaxol
US5440056A (en) * 1992-04-17 1995-08-08 Abbott Laboratories 9-deoxotaxane compounds
US5248796A (en) * 1992-06-18 1993-09-28 Bristol-Myers Squibb Company Taxol derivatives
GB9213077D0 (en) * 1992-06-19 1992-08-05 Erba Carlo Spa Polymerbound taxol derivatives
US5274137A (en) * 1992-06-23 1993-12-28 Nicolaou K C Intermediates for preparation of taxols
US5254580A (en) * 1993-01-19 1993-10-19 Bristol-Myers Squibb Company 7,8-cyclopropataxanes
US5294637A (en) * 1992-07-01 1994-03-15 Bristol-Myers Squibb Company Fluoro taxols
US5202448A (en) * 1992-08-14 1993-04-13 Napro Biotherapeutics, Inc. Processes of converting taxanes into baccatin III
WO1994005282A1 (en) * 1992-09-04 1994-03-17 The Scripps Research Institute Water soluble taxol derivatives
US5411984A (en) * 1992-10-16 1995-05-02 Virginia Tech Intellectual Properties, Inc. Water soluble analogs and prodrugs of taxol
US5380751A (en) * 1992-12-04 1995-01-10 Bristol-Myers Squibb Company 6,7-modified paclitaxels
US5279949A (en) * 1992-12-07 1994-01-18 Board Of Trustees Operating Michigan State University Process for the isolation and purification of taxol and taxanes from Taxus spp
US5339906A (en) * 1993-01-08 1994-08-23 Deere & Company Positon feedback mechanism for an implement
US5229172A (en) * 1993-01-19 1993-07-20 Medtronic, Inc. Modification of polymeric surface by graft polymerization
US5308641A (en) * 1993-01-19 1994-05-03 Medtronic, Inc. Biocompatibility of solid surfaces
US5350800A (en) * 1993-01-19 1994-09-27 Medtronic, Inc. Method for improving the biocompatibility of solid surfaces
US5400056A (en) * 1993-01-21 1995-03-21 Brooktree Corporation Apparatus for and method of processing and converting binary information to corresponding analog signals
US7279561B1 (en) * 1993-04-23 2007-10-09 Wyeth Anti-rapamycin monoclonal antibodies
US5412092A (en) * 1993-04-23 1995-05-02 Bristol-Myers Squibb Company N-substituted 2-azetidinones
US5395850A (en) * 1994-03-10 1995-03-07 Bristol-Myers Squibb Company 6,7-epoxy paclitaxels
US5837313A (en) * 1995-04-19 1998-11-17 Schneider (Usa) Inc Drug release stent coating process
US6120536A (en) * 1995-04-19 2000-09-19 Schneider (Usa) Inc. Medical devices with long term non-thrombogenic coatings
US6099562A (en) * 1996-06-13 2000-08-08 Schneider (Usa) Inc. Drug coating with topcoat
US6245026B1 (en) 1996-07-29 2001-06-12 Farallon Medsystems, Inc. Thermography catheter
US5924997A (en) * 1996-07-29 1999-07-20 Campbell; Thomas Henderson Catheter and method for the thermal mapping of hot spots in vascular lesions of the human body
JP2000504263A (ja) 1997-02-03 2000-04-11 アンジオガード インコーポレーテッド 血管のフィルター
US6425898B1 (en) * 1998-03-13 2002-07-30 Cordis Corporation Delivery apparatus for a self-expanding stent
US6241762B1 (en) * 1998-03-30 2001-06-05 Conor Medsystems, Inc. Expandable medical device with ductile hinges
US6153252A (en) * 1998-06-30 2000-11-28 Ethicon, Inc. Process for coating stents
CN1152025C (zh) * 1999-08-23 2004-06-02 杏林制药株式会社 取代的苄基噻唑烷-2,4-二酮衍生物
RU2169544C1 (ru) * 2000-05-16 2001-06-27 НПЦ "ИНТЕКО" ГП "Красная Звезда" Средство для поддержания просвета сосуда или полого органа
US6764507B2 (en) * 2000-10-16 2004-07-20 Conor Medsystems, Inc. Expandable medical device with improved spatial distribution
RU2332959C2 (ru) * 2001-02-16 2008-09-10 Эбботт Лэборатриз Васкьюлар Энтерпрайзиз Лимитед Имплантаты с fk506
BR0306858A (pt) * 2002-01-10 2004-11-03 Novartis Ag Sistemas de liberação de drogas para a prevenção e tratamento de doenças vasculares compreendendo rapamicina e derivados da mesma
EP1505931A1 (en) * 2002-05-20 2005-02-16 Orbus Medical Technologies, Inc. Drug eluting implantable medical device
US20050033417A1 (en) * 2003-07-31 2005-02-10 John Borges Coating for controlled release of a therapeutic agent
US20050064011A1 (en) * 2003-08-11 2005-03-24 Young-Ho Song Implantable or insertable medical devices containing phenolic compound for inhibition of restenosis
US20050037048A1 (en) * 2003-08-11 2005-02-17 Young-Ho Song Medical devices containing antioxidant and therapeutic agent
US8747881B2 (en) * 2003-12-19 2014-06-10 Cordis Corporation Intraluminal medical devices in combination with therapeutic agents
US7303758B2 (en) * 2004-01-20 2007-12-04 Cordis Corporation Local vascular delivery of mycophenolic acid in combination with rapamycin to prevent restenosis following vascular injury
US20050159809A1 (en) * 2004-01-21 2005-07-21 Medtronic Vascular, Inc. Implantable medical devices for treating or preventing restenosis
US7989490B2 (en) * 2004-06-02 2011-08-02 Cordis Corporation Injectable formulations of taxanes for cad treatment
US7846940B2 (en) * 2004-03-31 2010-12-07 Cordis Corporation Solution formulations of sirolimus and its analogs for CAD treatment
KR100511618B1 (ko) * 2005-01-17 2005-08-31 이경범 약물방출 조절형 다층 코팅 스텐트 및 이의 제조방법

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030060877A1 (en) * 2001-09-25 2003-03-27 Robert Falotico Coated medical devices for the treatment of vascular disease
CN1568166A (zh) * 2001-10-15 2005-01-19 荷姆泰克股份有限公司 预防再狭窄的涂层支架
CN1672745A (zh) * 2004-03-22 2005-09-28 科迪斯公司 局部血管递送依托泊苷与雷帕霉素的组合以防止血管损伤后的再狭窄

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101953721A (zh) * 2010-10-28 2011-01-26 东华大学 具有形状记忆功能的多层复合人造血管膜及其制备方法
CN101953721B (zh) * 2010-10-28 2013-06-05 东华大学 具有形状记忆功能的多层复合人造血管膜的制备方法
CN107296992A (zh) * 2017-06-13 2017-10-27 中国人民解放军总医院第附属医院 血管对接装置及包括该装置的血管伤救治装置
CN107296992B (zh) * 2017-06-13 2019-09-13 中国人民解放军总医院第一附属医院 血管对接装置及包括该装置的血管伤救治装置
CN116392648A (zh) * 2023-04-14 2023-07-07 中国科学院长春应用化学研究所 一种温度、炎症双响应性的抗凝复合涂层及其制备方法、应用
CN116392648B (zh) * 2023-04-14 2024-08-23 中国科学院长春应用化学研究所 一种温度、炎症双响应性的抗凝复合涂层及其制备方法、应用
WO2024222834A1 (zh) * 2023-04-27 2024-10-31 北京信立泰医疗器械有限公司 药物涂层及含有其的医疗装置、系统和制备方法

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IL209171A0 (en) 2011-01-31
US20080241215A1 (en) 2008-10-02
KR20080088510A (ko) 2008-10-02
IL209172A (en) 2017-04-30
MX2008004317A (es) 2009-02-27
AU2008201396A1 (en) 2008-10-16
RU2008111826A (ru) 2009-10-10
RU2481084C2 (ru) 2013-05-10
IL209172A0 (en) 2011-01-31
JP2008302206A (ja) 2008-12-18
AU2008201396B2 (en) 2013-03-07
IL190383A0 (en) 2009-09-22
EP1974758A3 (en) 2010-11-03
BRPI0803738A2 (pt) 2009-04-22
EP1974758A2 (en) 2008-10-01
JP5398996B2 (ja) 2014-01-29
KR101678369B1 (ko) 2016-11-23

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