KR101678369B1 - 재협착, 취약 플라크, ａａａ 및 뇌졸중을 치료하기 위한프로부콜 단독 또는 시롤리무스와 배합된 프로부콜의 국소혈관 전달 - Google Patents

재협착, 취약 플라크, ａａａ 및 뇌졸중을 치료하기 위한프로부콜 단독 또는 시롤리무스와 배합된 프로부콜의 국소혈관 전달 Download PDF

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KR101678369B1
KR101678369B1 KR1020080029074A KR20080029074A KR101678369B1 KR 101678369 B1 KR101678369 B1 KR 101678369B1 KR 1020080029074 A KR1020080029074 A KR 1020080029074A KR 20080029074 A KR20080029074 A KR 20080029074A KR 101678369 B1 KR101678369 B1 KR 101678369B1
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rapamycin
stent
coating
delete delete
drug
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KR1020080029074A
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Korean (ko)
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KR20080088510A (ko
Inventor
로버트 팔로티코
조나돈 제트 자오
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코디스 코포레이션
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L31/16—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/28—Materials for coating prostheses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/40—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/08—Materials for coatings
    • A61L31/10—Macromolecular materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/416—Anti-neoplastic or anti-proliferative or anti-restenosis or anti-angiogenic agents, e.g. paclitaxel, sirolimus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/45—Mixtures of two or more drugs, e.g. synergistic mixtures

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Surgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Dermatology (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Urology & Nephrology (AREA)
  • Composite Materials (AREA)
  • Cardiology (AREA)
  • Materials Engineering (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Materials For Medical Uses (AREA)
  • Prostheses (AREA)
  • Media Introduction/Drainage Providing Device (AREA)
  • Surgical Instruments (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
KR1020080029074A 2007-03-28 2008-03-28 재협착, 취약 플라크, ａａａ 및 뇌졸중을 치료하기 위한프로부콜 단독 또는 시롤리무스와 배합된 프로부콜의 국소혈관 전달 Expired - Fee Related KR101678369B1 (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11/692,744 US20080241215A1 (en) 2007-03-28 2007-03-28 Local vascular delivery of probucol alone or in combination with sirolimus to treat restenosis, vulnerable plaque, aaa and stroke
US11/692,744 2007-03-28

Publications (2)

Publication Number Publication Date
KR20080088510A KR20080088510A (ko) 2008-10-02
KR101678369B1 true KR101678369B1 (ko) 2016-11-23

Family

ID=39642698

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020080029074A Expired - Fee Related KR101678369B1 (ko) 2007-03-28 2008-03-28 재협착, 취약 플라크, ａａａ 및 뇌졸중을 치료하기 위한프로부콜 단독 또는 시롤리무스와 배합된 프로부콜의 국소혈관 전달

Country Status (10)

Country Link
US (1) US20080241215A1 (enExample)
EP (1) EP1974758A3 (enExample)
JP (1) JP5398996B2 (enExample)
KR (1) KR101678369B1 (enExample)
CN (1) CN101543659A (enExample)
AU (1) AU2008201396B2 (enExample)
BR (1) BRPI0803738A2 (enExample)
IL (3) IL209172A (enExample)
MX (1) MX2008004317A (enExample)
RU (1) RU2481084C2 (enExample)

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CN101474455B (zh) 2009-01-19 2012-07-25 北京天地和协科技有限公司 一种储存和释放多种药物的纳米级微孔结构药物洗脱器械及制备方法
US20100280600A1 (en) * 2009-04-30 2010-11-04 Vipul Bhupendra Dave Dual drug stent
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EP2380604A1 (en) 2010-04-19 2011-10-26 InnoRa Gmbh Improved coating formulations for scoring or cutting balloon catheters
CN101953721B (zh) * 2010-10-28 2013-06-05 东华大学 具有形状记忆功能的多层复合人造血管膜的制备方法
SG11201401329VA (en) 2011-10-14 2014-05-29 Innora Gmbh Improved formulations for drug-coated medical devices
US20180122351A1 (en) * 2016-10-31 2018-05-03 Garmin Switzerland Gmbh Transducer mounting device
WO2018163055A1 (en) * 2017-03-06 2018-09-13 Cardiovascular Lab S.P.A. O Brevemente Cv Lab S.P.A. Multilayer luminal endoprosthesis and manufacturing method
CN107296992B (zh) * 2017-06-13 2019-09-13 中国人民解放军总医院第一附属医院 血管对接装置及包括该装置的血管伤救治装置
US11654036B2 (en) 2020-05-26 2023-05-23 Elixir Medical Corporation Anticoagulant compounds and methods and devices for their use
WO2021242783A1 (en) * 2020-05-26 2021-12-02 Elixir Medical Corporation Anticoagulant compounds and methods and devices for their use
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WO2024030418A2 (en) * 2022-08-02 2024-02-08 The Secant Group, Llc Biodegradable, elastomeric anastomotic tissue junction stabilizer
WO2024155994A1 (en) 2023-01-20 2024-07-25 Texas Medical Center Methods and systems for transcaval treatment of aneurysms
CN116392648B (zh) * 2023-04-14 2024-08-23 中国科学院长春应用化学研究所 一种温度、炎症双响应性的抗凝复合涂层及其制备方法、应用
WO2024222834A1 (zh) * 2023-04-27 2024-10-31 北京信立泰医疗器械有限公司 药物涂层及含有其的医疗装置、系统和制备方法

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Also Published As

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IL190383A0 (en) 2009-09-22
IL209172A0 (en) 2011-01-31
EP1974758A2 (en) 2008-10-01
AU2008201396A1 (en) 2008-10-16
IL209172A (en) 2017-04-30
BRPI0803738A2 (pt) 2009-04-22
KR20080088510A (ko) 2008-10-02
EP1974758A3 (en) 2010-11-03
IL209171A0 (en) 2011-01-31
RU2481084C2 (ru) 2013-05-10
AU2008201396B2 (en) 2013-03-07
JP2008302206A (ja) 2008-12-18
MX2008004317A (es) 2009-02-27
US20080241215A1 (en) 2008-10-02
CN101543659A (zh) 2009-09-30
RU2008111826A (ru) 2009-10-10
JP5398996B2 (ja) 2014-01-29

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