RU2481084C2 - Локальная сосудистая доставка пробукола, одного или в комбинации с сиролимусом, для лечения рестеноза, уязвимых бляшек, ааа (аневризмы брюшной аорты) и инсульта - Google Patents

Локальная сосудистая доставка пробукола, одного или в комбинации с сиролимусом, для лечения рестеноза, уязвимых бляшек, ааа (аневризмы брюшной аорты) и инсульта Download PDF

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Publication number
RU2481084C2
RU2481084C2 RU2008111826/15A RU2008111826A RU2481084C2 RU 2481084 C2 RU2481084 C2 RU 2481084C2 RU 2008111826/15 A RU2008111826/15 A RU 2008111826/15A RU 2008111826 A RU2008111826 A RU 2008111826A RU 2481084 C2 RU2481084 C2 RU 2481084C2
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Russia
Prior art keywords
rapamycin
coating
medical device
stent
polymeric material
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RU2008111826/15A
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English (en)
Russian (ru)
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RU2008111826A (ru
Inventor
Роберт ФАЛОТИКО
Джонатон З. ЧЖАО
Original Assignee
Кордис Корпорейшн
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Application filed by Кордис Корпорейшн filed Critical Кордис Корпорейшн
Publication of RU2008111826A publication Critical patent/RU2008111826A/ru
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/28—Materials for coating prostheses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/40—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/08—Materials for coatings
    • A61L31/10—Macromolecular materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L31/16—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/416—Anti-neoplastic or anti-proliferative or anti-restenosis or anti-angiogenic agents, e.g. paclitaxel, sirolimus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/45—Mixtures of two or more drugs, e.g. synergistic mixtures

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Surgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Dermatology (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Urology & Nephrology (AREA)
  • Composite Materials (AREA)
  • Cardiology (AREA)
  • Materials Engineering (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Materials For Medical Uses (AREA)
  • Prostheses (AREA)
  • Media Introduction/Drainage Providing Device (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Surgical Instruments (AREA)
RU2008111826/15A 2007-03-28 2008-03-27 Локальная сосудистая доставка пробукола, одного или в комбинации с сиролимусом, для лечения рестеноза, уязвимых бляшек, ааа (аневризмы брюшной аорты) и инсульта RU2481084C2 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11/692,744 2007-03-28
US11/692,744 US20080241215A1 (en) 2007-03-28 2007-03-28 Local vascular delivery of probucol alone or in combination with sirolimus to treat restenosis, vulnerable plaque, aaa and stroke

Publications (2)

Publication Number Publication Date
RU2008111826A RU2008111826A (ru) 2009-10-10
RU2481084C2 true RU2481084C2 (ru) 2013-05-10

Family

ID=39642698

Family Applications (1)

Application Number Title Priority Date Filing Date
RU2008111826/15A RU2481084C2 (ru) 2007-03-28 2008-03-27 Локальная сосудистая доставка пробукола, одного или в комбинации с сиролимусом, для лечения рестеноза, уязвимых бляшек, ааа (аневризмы брюшной аорты) и инсульта

Country Status (10)

Country Link
US (1) US20080241215A1 (enExample)
EP (1) EP1974758A3 (enExample)
JP (1) JP5398996B2 (enExample)
KR (1) KR101678369B1 (enExample)
CN (1) CN101543659A (enExample)
AU (1) AU2008201396B2 (enExample)
BR (1) BRPI0803738A2 (enExample)
IL (3) IL190383A0 (enExample)
MX (1) MX2008004317A (enExample)
RU (1) RU2481084C2 (enExample)

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US20090155337A1 (en) * 2007-11-12 2009-06-18 Endologix, Inc. Method and agent for in-situ stabilization of vascular tissue
CN101474455B (zh) 2009-01-19 2012-07-25 北京天地和协科技有限公司 一种储存和释放多种药物的纳米级微孔结构药物洗脱器械及制备方法
US20100280600A1 (en) * 2009-04-30 2010-11-04 Vipul Bhupendra Dave Dual drug stent
EP2380605A1 (en) 2010-04-19 2011-10-26 InnoRa Gmbh Improved formulations for drug-coated medical devices
EP2380604A1 (en) 2010-04-19 2011-10-26 InnoRa Gmbh Improved coating formulations for scoring or cutting balloon catheters
EP2383000A1 (en) 2010-04-19 2011-11-02 InnoRa Gmbh Limus-coated medical devices
CN101953721B (zh) * 2010-10-28 2013-06-05 东华大学 具有形状记忆功能的多层复合人造血管膜的制备方法
US9415140B2 (en) 2011-10-14 2016-08-16 Innora Gmbh Formulations for drug-coated medical devices
US20180122351A1 (en) * 2016-10-31 2018-05-03 Garmin Switzerland Gmbh Transducer mounting device
CA3054264A1 (en) * 2017-03-06 2018-09-13 Cardiovascular Lab S.P.A. O Brevemente Cv Lab S.P.A. Multilayer luminal endoprosthesis and manufacturing method
CN107296992B (zh) * 2017-06-13 2019-09-13 中国人民解放军总医院第一附属医院 血管对接装置及包括该装置的血管伤救治装置
WO2021242783A1 (en) * 2020-05-26 2021-12-02 Elixir Medical Corporation Anticoagulant compounds and methods and devices for their use
US11654036B2 (en) 2020-05-26 2023-05-23 Elixir Medical Corporation Anticoagulant compounds and methods and devices for their use
US12318563B1 (en) 2021-02-02 2025-06-03 Taurus Vascular, Inc. Methods and systems for transcaval treatment of aneurysms
US12310837B1 (en) 2024-01-22 2025-05-27 Taurus Vascular, Inc. Methods and systems for transcaval treatment of aneurysms
WO2024030418A2 (en) * 2022-08-02 2024-02-08 The Secant Group, Llc Biodegradable, elastomeric anastomotic tissue junction stabilizer
WO2024155994A1 (en) 2023-01-20 2024-07-25 Texas Medical Center Methods and systems for transcaval treatment of aneurysms
CN116392648B (zh) * 2023-04-14 2024-08-23 中国科学院长春应用化学研究所 一种温度、炎症双响应性的抗凝复合涂层及其制备方法、应用
JP2026514507A (ja) * 2023-04-27 2026-05-11 北京信立泰医▲療▼▲器▼械有限公司 薬物コーティング、およびそれを有する医療デバイス、システムおよび製造方法

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Also Published As

Publication number Publication date
MX2008004317A (es) 2009-02-27
IL209172A0 (en) 2011-01-31
AU2008201396B2 (en) 2013-03-07
JP5398996B2 (ja) 2014-01-29
AU2008201396A1 (en) 2008-10-16
KR20080088510A (ko) 2008-10-02
IL209171A0 (en) 2011-01-31
EP1974758A2 (en) 2008-10-01
KR101678369B1 (ko) 2016-11-23
IL209172A (en) 2017-04-30
EP1974758A3 (en) 2010-11-03
US20080241215A1 (en) 2008-10-02
IL190383A0 (en) 2009-09-22
RU2008111826A (ru) 2009-10-10
BRPI0803738A2 (pt) 2009-04-22
JP2008302206A (ja) 2008-12-18
CN101543659A (zh) 2009-09-30

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