RU2481084C2 - Локальная сосудистая доставка пробукола, одного или в комбинации с сиролимусом, для лечения рестеноза, уязвимых бляшек, ааа (аневризмы брюшной аорты) и инсульта - Google Patents

Локальная сосудистая доставка пробукола, одного или в комбинации с сиролимусом, для лечения рестеноза, уязвимых бляшек, ааа (аневризмы брюшной аорты) и инсульта Download PDF

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Publication number
RU2481084C2
RU2481084C2 RU2008111826/15A RU2008111826A RU2481084C2 RU 2481084 C2 RU2481084 C2 RU 2481084C2 RU 2008111826/15 A RU2008111826/15 A RU 2008111826/15A RU 2008111826 A RU2008111826 A RU 2008111826A RU 2481084 C2 RU2481084 C2 RU 2481084C2
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Prior art keywords
rapamycin
coating
medical device
stent
polymeric material
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RU2008111826/15A
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English (en)
Russian (ru)
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RU2008111826A (ru
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Роберт ФАЛОТИКО
Джонатон З. ЧЖАО
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Кордис Корпорейшн
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Application filed by Кордис Корпорейшн filed Critical Кордис Корпорейшн
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/28Materials for coating prostheses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/40Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/08Materials for coatings
    • A61L31/10Macromolecular materials
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L31/16Biologically active materials, e.g. therapeutic substances
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/416Anti-neoplastic or anti-proliferative or anti-restenosis or anti-angiogenic agents, e.g. paclitaxel, sirolimus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/45Mixtures of two or more drugs, e.g. synergistic mixtures

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Vascular Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Surgery (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Dermatology (AREA)
  • Transplantation (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Composite Materials (AREA)
  • Materials Engineering (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Materials For Medical Uses (AREA)
  • Media Introduction/Drainage Providing Device (AREA)
  • Prostheses (AREA)
  • Surgical Instruments (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
RU2008111826/15A 2007-03-28 2008-03-27 Локальная сосудистая доставка пробукола, одного или в комбинации с сиролимусом, для лечения рестеноза, уязвимых бляшек, ааа (аневризмы брюшной аорты) и инсульта RU2481084C2 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11/692,744 US20080241215A1 (en) 2007-03-28 2007-03-28 Local vascular delivery of probucol alone or in combination with sirolimus to treat restenosis, vulnerable plaque, aaa and stroke
US11/692,744 2007-03-28

Publications (2)

Publication Number Publication Date
RU2008111826A RU2008111826A (ru) 2009-10-10
RU2481084C2 true RU2481084C2 (ru) 2013-05-10

Family

ID=39642698

Family Applications (1)

Application Number Title Priority Date Filing Date
RU2008111826/15A RU2481084C2 (ru) 2007-03-28 2008-03-27 Локальная сосудистая доставка пробукола, одного или в комбинации с сиролимусом, для лечения рестеноза, уязвимых бляшек, ааа (аневризмы брюшной аорты) и инсульта

Country Status (10)

Country Link
US (1) US20080241215A1 (enExample)
EP (1) EP1974758A3 (enExample)
JP (1) JP5398996B2 (enExample)
KR (1) KR101678369B1 (enExample)
CN (1) CN101543659A (enExample)
AU (1) AU2008201396B2 (enExample)
BR (1) BRPI0803738A2 (enExample)
IL (3) IL209172A (enExample)
MX (1) MX2008004317A (enExample)
RU (1) RU2481084C2 (enExample)

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CN101474455B (zh) 2009-01-19 2012-07-25 北京天地和协科技有限公司 一种储存和释放多种药物的纳米级微孔结构药物洗脱器械及制备方法
US20100280600A1 (en) * 2009-04-30 2010-11-04 Vipul Bhupendra Dave Dual drug stent
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EP2383000A1 (en) 2010-04-19 2011-11-02 InnoRa Gmbh Limus-coated medical devices
EP2380604A1 (en) 2010-04-19 2011-10-26 InnoRa Gmbh Improved coating formulations for scoring or cutting balloon catheters
CN101953721B (zh) * 2010-10-28 2013-06-05 东华大学 具有形状记忆功能的多层复合人造血管膜的制备方法
SG11201401329VA (en) 2011-10-14 2014-05-29 Innora Gmbh Improved formulations for drug-coated medical devices
US20180122351A1 (en) * 2016-10-31 2018-05-03 Garmin Switzerland Gmbh Transducer mounting device
WO2018163055A1 (en) * 2017-03-06 2018-09-13 Cardiovascular Lab S.P.A. O Brevemente Cv Lab S.P.A. Multilayer luminal endoprosthesis and manufacturing method
CN107296992B (zh) * 2017-06-13 2019-09-13 中国人民解放军总医院第一附属医院 血管对接装置及包括该装置的血管伤救治装置
US11654036B2 (en) 2020-05-26 2023-05-23 Elixir Medical Corporation Anticoagulant compounds and methods and devices for their use
WO2021242783A1 (en) * 2020-05-26 2021-12-02 Elixir Medical Corporation Anticoagulant compounds and methods and devices for their use
US12318563B1 (en) 2021-02-02 2025-06-03 Taurus Vascular, Inc. Methods and systems for transcaval treatment of aneurysms
US12310837B1 (en) 2024-01-22 2025-05-27 Taurus Vascular, Inc. Methods and systems for transcaval treatment of aneurysms
WO2024030418A2 (en) * 2022-08-02 2024-02-08 The Secant Group, Llc Biodegradable, elastomeric anastomotic tissue junction stabilizer
WO2024155994A1 (en) 2023-01-20 2024-07-25 Texas Medical Center Methods and systems for transcaval treatment of aneurysms
CN116392648B (zh) * 2023-04-14 2024-08-23 中国科学院长春应用化学研究所 一种温度、炎症双响应性的抗凝复合涂层及其制备方法、应用
WO2024222834A1 (zh) * 2023-04-27 2024-10-31 北京信立泰医疗器械有限公司 药物涂层及含有其的医疗装置、系统和制备方法

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Also Published As

Publication number Publication date
IL190383A0 (en) 2009-09-22
IL209172A0 (en) 2011-01-31
EP1974758A2 (en) 2008-10-01
AU2008201396A1 (en) 2008-10-16
IL209172A (en) 2017-04-30
BRPI0803738A2 (pt) 2009-04-22
KR20080088510A (ko) 2008-10-02
EP1974758A3 (en) 2010-11-03
IL209171A0 (en) 2011-01-31
AU2008201396B2 (en) 2013-03-07
JP2008302206A (ja) 2008-12-18
MX2008004317A (es) 2009-02-27
KR101678369B1 (ko) 2016-11-23
US20080241215A1 (en) 2008-10-02
CN101543659A (zh) 2009-09-30
RU2008111826A (ru) 2009-10-10
JP5398996B2 (ja) 2014-01-29

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