CN101543597A - Medicine composition for nourishing spleen and kidney and building up healthful vital energy and preparation method thereof - Google Patents

Medicine composition for nourishing spleen and kidney and building up healthful vital energy and preparation method thereof Download PDF

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Publication number
CN101543597A
CN101543597A CN200810102951A CN200810102951A CN101543597A CN 101543597 A CN101543597 A CN 101543597A CN 200810102951 A CN200810102951 A CN 200810102951A CN 200810102951 A CN200810102951 A CN 200810102951A CN 101543597 A CN101543597 A CN 101543597A
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parts
kidney
fructus
radix
medicine composition
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魏晓伟
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TECH-SKY TECHNOLOGY (BEIJING) Co Ltd
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TECH-SKY TECHNOLOGY (BEIJING) Co Ltd
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Abstract

The invention discloses a medicine composition for nourishing spleen and kidney and building up healthful vital energy, which comprises functional ingredients and/or pharmaceutically acceptable carriers, wherein the functional ingredients are prepared by extracting codonopsis pilosula, radix astragali, barbary wolfberry fruit, Chinese angelica, glossy privet fruit, red-rooted salvia root, bighead atractylodes rhizome, south dodder seed, malaytea scurfpea fruit, poria cocos, white paeony root, coix seed, gardenia, and the like. The medicine composition has the efficacies of nourishing spleen and kidney and building up healthful vital energy, is applied for reducing the side reactions of patients with beast cancer caused by postoperative chemotherapy and radiotherapy, improving the immunologic function of a human body and is applied to the diseases caused by spleen and kidney weakness.

Description

Drug regimen of a kind of invigorating spleen and kidney, reinforcing body resistance and preparation method thereof
Technical field:
The invention belongs to technical field of traditional Chinese medicine pharmacy, be specifically related to drug regimen of a kind of invigorating spleen and kidney, reinforcing body resistance and preparation method thereof.
Technical background
Breast carcinoma is meant the malignant tumor that originates from breast duct epithelium and lobules of mammary gland, is common malignancy the most among the whole world women.Worldwide, some developed countries of west are as North America and most of European countries, district occurred frequently for women with breast cancer, the highest sickness rate sees the white man of Hawaiian white man and British Columbia, Canada, and sickness rate is up to 80,/10 ten thousand, and only is 12,/10 ten thousand at Japanese sickness rate.In same country, white man's sickness rate is higher than Black people.Minimum sickness rate sees the crowd in Africa and Asia, is 10~15,/10 ten thousand.Chinese and Japanese in the U.S., though the sickness rate of its women with breast cancer does not have white man high like that, oneself exceeds 3 times than the Chinese of Singapore and people in Japan.China belongs to that breast carcinoma is low sends out the district, but its sickness rate rises just year by year in recent years, and the city is higher than the rural area, and the coastal area is higher than interiorly.Shanghai, Beijing, Tianjin and coastal area are the hotspots of Chinese breast carcinoma.Especially with Shanghai for the highest, leapt to the first place of women's malignant tumor.
Stem reality in the face of the breast cancer incidence growth, the medical science men think after investigating, why breast carcinoma becomes dangerous " beauty killer ", except the Inheritance history, suffered from the factors such as breast carcinoma or optimum breast tumor history in the past, closely related with all bad social environmental factor.
Clinical to early, mid-term patient be first-selected with the operative treatment, the middle and advanced stage patient is appropriate with Comprehensive Treatment then, this moment just can be in conjunction with the treatment of the traditional Chinese medical science to breast carcinoma.
The traditional Chinese medical science shows unique characteristics aspect the preventing and treating of breast carcinoma, for breast carcinoma later stage patient, by QI invigorating, nourish blood, invigorate blood circulation, the diffusion of effect control cancer cell such as eliminating stagnation, change silt, increase normal body, prolong operation receiveing person's life-span, improve quality of the life.For patient with operation, Chinese traditional treatment can be played the effect of anticancer analgetic before the art, and the adjuvant treatment effect of postoperative is then more remarkable.Doctor trained in Western medicine is generally taked radiotherapy, chemotherapy maneuver kill cancer cell for the postoperative personnel, prevents diffusion.Yet, to put, chemotherapy also killed normal human body cell in kill cancer cell, bring injury to human body, the most significant symptom makes human leukocytes reduce in a large number exactly, causes body immunity to descend, and resistance against diseases is poor.The traditional Chinese medical science is then paid much attention to the utilization of tonifying speen and tonifying kidney method, by its different state of an illness or based on spleen reinforcing, or based on the kidney invigorating, or reinforce spleen and kidney together.Think tonifying speen and tonifying kidney, not only can reinforcing body resistance, improve the anti-evil ability of body, the improvement of the weak state of rough bamboo mat is arranged, strengthen self anti-cancer ability.And can resist or alleviate put, toxic and side effects such as chemotherapy, help that the patient accepts to put smoothly, chemotherapy, thereby improve whole curative effect.
Summary of the invention:
One of purpose of the present invention provides the drug regimen of a kind of invigorating spleen and kidney, reinforcing body resistance.
Another object of the present invention provides the preparation method of this drug regimen.
Chinese medicine of the present invention is made up of active ingredient and/or pharmaceutically acceptable carrier, and wherein said active ingredient is made (part is unit of weight) by following raw materials according:
1. write out a prescription:
100-200 parts of 100-300 parts of Fructus Lycii of 100-300 parts of Radixs Astragali of Radix Codonopsis
100-300 parts of 100-200 parts of Radix Salviae Miltiorrhizaes of 100-300 parts of Fructus Ligustri Lucidi of Radix Angelicae Sinensis
100-200 parts of 100-200 parts of Fructus Psoraleaes of 100-200 parts of Semen Cuscutae of the Rhizoma Atractylodis Macrocephalae
100-200 parts of 100-300 parts of Semen Coiciss of 100-200 parts of Radix Paeoniae Albas of Poria
100-200 parts of Fructus Gardeniae
The active component that preferred following raw materials according is made, curative effect is better:
100 parts of 150 parts of Fructus Lycii of 150 parts of Radixs Astragali of Radix Codonopsis
150 parts of 100 parts of Radix Salviae Miltiorrhizaes of 150 parts of Fructus Ligustri Lucidi of Radix Angelicae Sinensis
100 parts of 100 parts of Fructus Psoraleaes of 100 parts of Semen Cuscutae of the Rhizoma Atractylodis Macrocephalae
100 parts of 150 parts of Semen Coiciss of 100 portions of Radix Paeoniae Albas of Poria
100 parts of Fructus Gardeniae
The active ingredient preparation method of Chinese medicine of the present invention can be that raw material is dry respectively, and levigation mixes.It also can be the conventional method preparation of adopting herbal pharmaceutical.These pharmacy conventional methods can be water extract-alcohol precipitation or ethanol extract from water precipitation, also have other extracting method in addition, specifically " pharmaceutics of Chinese drugs " published referring to Cao Chunlin chief editor's Shanghai science tech publishing house.
The following preparation method preparation of preferred employing:
2. preparation technology
(1) Radix Codonopsis, the Radix Astragali, Radix Angelicae Sinensis add 85% alcohol dipping 2 times, and each 12-24 hours, filter, decompression filtrate recycling ethanol is condensed into the thick paste shape, and vacuum drying below 80 ℃ becomes dried cream;
(2) medical materials such as all the other Fructus Lycii, Fructus Ligustri Lucidi, Radix Salviae Miltiorrhizae, the Rhizoma Atractylodis Macrocephalae, Semen Cuscutae, Fructus Psoraleae, Poria, the Radix Paeoniae Alba, Semen Coicis, Fructus Gardeniae add 10 times of decoctings and boil 2 times, each 1-2 hours, filter, merging filtrate, filtrate is condensed into the clear paste that relative density is 1.08~1.14 (50~60 ℃), adds 3 times of amount ethanol, stirs evenly, be heated to 60 ℃, left standstill 12-24 hours, and filtered decompression filtrate recycling ethanol, be condensed into the thick paste shape, vacuum drying below 80 ℃ becomes dried cream;
(3) step (1) get dry extract is got dry extract with step (2) mix, be ground into fine powder, add acceptable accessories and make different preparations such as granule, sheet, capsule.
Adopt mutual compatibility of above-mentioned raw material of Chinese medicine and preparation method thereof, full side has the effect of invigorating spleen and kidney, reinforcing body resistance, is used to alleviate that breast carcinoma patient postoperative is put, chemotherapy side effect, the caused disease of human body immunity improving function and weakness of the spleen and kidney.
By the following examples technical scheme of the present invention is described further.
Embodiment 1: the preparation method of granule
1. write out a prescription:
100 parts of 150 parts of Fructus Lycii of 150 parts of Radixs Astragali of Radix Codonopsis
150 parts of 100 parts of Radix Salviae Miltiorrhizaes of 150 parts of Fructus Ligustri Lucidi of Radix Angelicae Sinensis
100 parts of 100 parts of Fructus Psoraleaes of 100 parts of Semen Cuscutae of the Rhizoma Atractylodis Macrocephalae
100 parts of 150 parts of Semen Coiciss of 100 portions of Radix Paeoniae Albas of Poria
100 parts of Fructus Gardeniae
2. preparation technology
(1) Radix Codonopsis, the Radix Astragali, Radix Angelicae Sinensis add 85% alcohol dipping 2 times, and 24 hours for the first time, 12 hours for the second time, filter, decompression filtrate recycling ethanol is condensed into the thick paste shape, and vacuum drying below 80 ℃ becomes dried cream;
(2) medical materials such as all the other Fructus Lycii, Fructus Ligustri Lucidi, Radix Salviae Miltiorrhizae, the Rhizoma Atractylodis Macrocephalae, Semen Cuscutae, Fructus Psoraleae, Poria, the Radix Paeoniae Alba, Semen Coicis, Fructus Gardeniae add 10 times of decoctings and boil 2 times, 2 hours for the first time, filter in 1 hour for the second time, merging filtrate, filtrate is condensed into the clear paste that relative density is 1.08~1.14 (50~60 ℃), adds 3 times of amount ethanol, stirs evenly, be heated to 60 ℃, left standstill 12 hours, and filtered decompression filtrate recycling ethanol, be condensed into the thick paste shape, vacuum drying below 80 ℃ becomes dried cream;
(3) step (1) get dry extract is got dry extract with step (2) mix, add cane sugar powder, mixing is made granule, drying, promptly.
Embodiment 2: the preparation method of tablet
1. write out a prescription:
100 parts of 150 parts of Fructus Lycii of 150 parts of Radixs Astragali of Radix Codonopsis
150 parts of 100 parts of Radix Salviae Miltiorrhizaes of 150 parts of Fructus Ligustri Lucidi of Radix Angelicae Sinensis
100 parts of 100 parts of Fructus Psoraleaes of 100 parts of Semen Cuscutae of the Rhizoma Atractylodis Macrocephalae
100 parts of 150 parts of Semen Coiciss of 100 portions of Radix Paeoniae Albas of Poria
100 parts of Fructus Gardeniae
2. preparation technology
(1) Radix Codonopsis, the Radix Astragali, Radix Angelicae Sinensis add 85% alcohol dipping 2 times, and 24 hours for the first time, 12 hours for the second time, filter, decompression filtrate recycling ethanol is condensed into the thick paste shape, and vacuum drying below 80 ℃ becomes dried cream;
(2) medical materials such as all the other Fructus Lycii, Fructus Ligustri Lucidi, Radix Salviae Miltiorrhizae, the Rhizoma Atractylodis Macrocephalae, Semen Cuscutae, Fructus Psoraleae, Poria, the Radix Paeoniae Alba, Semen Coicis, Fructus Gardeniae add 10 times of decoctings and boil 2 times, 2 hours for the first time, filter in 1 hour for the second time, merging filtrate, filtrate is condensed into the clear paste that relative density is 1.08~1.14 (50~60 ℃), adds 3 times of amount ethanol, stirs evenly, be heated to 60 ℃, left standstill 12 hours, and filtered decompression filtrate recycling ethanol, be condensed into the thick paste shape, vacuum drying below 80 ℃ becomes dried cream;
(3) step (1) get dry extract is got dry extract with step (2) mix, pulverize, sieve, add starch, magnesium stearate, tabletting, promptly.
Embodiment 3: the preparation method of capsule
1. write out a prescription:
100 parts of 150 parts of Fructus Lycii of 150 parts of Radixs Astragali of Radix Codonopsis
150 parts of 100 parts of Radix Salviae Miltiorrhizaes of 150 parts of Fructus Ligustri Lucidi of Radix Angelicae Sinensis
100 parts of 100 parts of Fructus Psoraleaes of 100 parts of Semen Cuscutae of the Rhizoma Atractylodis Macrocephalae
100 parts of 150 parts of Semen Coiciss of 100 portions of Radix Paeoniae Albas of Poria
100 parts of Fructus Gardeniae
2. preparation technology
(1) Radix Codonopsis, the Radix Astragali, Radix Angelicae Sinensis add 85% alcohol dipping 2 times, and 24 hours for the first time, 12 hours for the second time, filter, decompression filtrate recycling ethanol is condensed into the thick paste shape, and vacuum drying below 80 ℃ becomes dried cream;
(2) medical materials such as all the other Fructus Lycii, Fructus Ligustri Lucidi, Radix Salviae Miltiorrhizae, the Rhizoma Atractylodis Macrocephalae, Semen Cuscutae, Fructus Psoraleae, Poria, the Radix Paeoniae Alba, Semen Coicis, Fructus Gardeniae add 10 times of decoctings and boil 2 times, 2 hours for the first time, filter in 1 hour for the second time, merging filtrate, filtrate is condensed into the clear paste that relative density is 1.08~1.14 (50~60 ℃), adds 3 times of amount ethanol, stirs evenly, be heated to 60 ℃, left standstill 12 hours, and filtered decompression filtrate recycling ethanol, be condensed into the thick paste shape, vacuum drying below 80 ℃ becomes dried cream;
(3) step (1) get dry extract is got dry extract with step (2) mix, pulverize, sieve, add starch, mixing is made granule, and drying incapsulates, promptly.

Claims (5)

1, the drug regimen of a kind of invigorating spleen and kidney, reinforcing body resistance is characterized in that being made up of active ingredient and/or pharmaceutically acceptable carrier, and wherein said active ingredient is made by following raw materials according:
100-200 parts of 100-300 parts of Fructus Lycii of 100-300 parts of Radixs Astragali of Radix Codonopsis
100-300 parts of 100-200 parts of Radix Salviae Miltiorrhizaes of 100-300 parts of Fructus Ligustri Lucidi of Radix Angelicae Sinensis
100-200 parts of 100-200 parts of Fructus Psoraleaes of 100-200 parts of Semen Cuscutae of the Rhizoma Atractylodis Macrocephalae
100-200 parts of 100-300 parts of Semen Coiciss of 100-200 parts of Radix Paeoniae Albas of Poria
100-200 parts of Fructus Gardeniae.
2, the drug regimen of a kind of invigorating spleen and kidney according to claim 1, reinforcing body resistance is characterized in that wherein preparing the preferred following raw materials according of described active ingredient:
100 parts of 150 parts of Fructus Lycii of 150 parts of Radixs Astragali of Radix Codonopsis
150 parts of 100 parts of Radix Salviae Miltiorrhizaes of 150 parts of Fructus Ligustri Lucidi of Radix Angelicae Sinensis
100 parts of 100 parts of Fructus Psoraleaes of 100 parts of Semen Cuscutae of the Rhizoma Atractylodis Macrocephalae
100 parts of 150 parts of Semen Coiciss of 100 portions of Radix Paeoniae Albas of Poria
100 parts of Fructus Gardeniae.
3, according to the drug regimen of the described a kind of invigorating spleen and kidney of claim 1-2, reinforcing body resistance, it is characterized in that adopting following method to make:
(1) Radix Codonopsis, the Radix Astragali, Radix Angelicae Sinensis add 85% alcohol dipping 2 times, and each 12-24 hours, filter, decompression filtrate recycling ethanol is condensed into the thick paste shape, and vacuum drying below 80 ℃ becomes dried cream;
(2) medical materials such as all the other Fructus Lycii, Fructus Ligustri Lucidi, Radix Salviae Miltiorrhizae, the Rhizoma Atractylodis Macrocephalae, Semen Cuscutae, Fructus Psoraleae, Poria, the Radix Paeoniae Alba, Semen Coicis, Fructus Gardeniae add 10 times of decoctings and boil 2 times, each 1-2 hours, filter, merging filtrate, filtrate is condensed into the clear paste that relative density is 1.08~1.14 (50~60 ℃), adds 3 times of amount ethanol, stirs evenly, be heated to 60 ℃, left standstill 12-24 hours, and filtered decompression filtrate recycling ethanol, be condensed into the thick paste shape, vacuum drying below 80 ℃ becomes dried cream;
(3) step (1) get dry extract is got dry extract with step (2) mix, be ground into fine powder, add acceptable accessories and make different preparations such as granule, sheet, capsule.
4,, it is characterized in that this Chinese medicine composition is an oral formulations according to the drug regimen of any one described a kind of invigorating spleen and kidney, reinforcing body resistance among the claim 1-3.
5,, it is characterized in that this Chinese medicine composition can be made into granule, capsule, tablet according to the drug regimen of the described a kind of invigorating spleen and kidney of claim 3-4, reinforcing body resistance.
CN200810102951A 2008-03-28 2008-03-28 Medicine composition for nourishing spleen and kidney and building up healthful vital energy and preparation method thereof Pending CN101543597A (en)

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103230477A (en) * 2013-05-10 2013-08-07 肖月升 Traditional Chinese medicine for treating malignant tumor and therapeutic method
CN104288598A (en) * 2014-09-19 2015-01-21 邓立华 Medicinal diet formula for nursing after radiotherapy and preparation method of medical diet formula
CN105055850A (en) * 2015-07-30 2015-11-18 庞群 Chinese herbal medicament for treating responses to breast cancer radiotherapy and chemotherapy

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103230477A (en) * 2013-05-10 2013-08-07 肖月升 Traditional Chinese medicine for treating malignant tumor and therapeutic method
CN104288598A (en) * 2014-09-19 2015-01-21 邓立华 Medicinal diet formula for nursing after radiotherapy and preparation method of medical diet formula
CN105055850A (en) * 2015-07-30 2015-11-18 庞群 Chinese herbal medicament for treating responses to breast cancer radiotherapy and chemotherapy

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Open date: 20090930