CN101259263A - Medicaments assembly for treating stomach-heat moisture resistance type obesity and preparation thereof - Google Patents

Medicaments assembly for treating stomach-heat moisture resistance type obesity and preparation thereof Download PDF

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Publication number
CN101259263A
CN101259263A CNA2008101045201A CN200810104520A CN101259263A CN 101259263 A CN101259263 A CN 101259263A CN A2008101045201 A CNA2008101045201 A CN A2008101045201A CN 200810104520 A CN200810104520 A CN 200810104520A CN 101259263 A CN101259263 A CN 101259263A
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parts
cortex
pericarpium citri
moisture resistance
type obesity
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CNA2008101045201A
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Chinese (zh)
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颜丽君
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Beijing Zhongke Renhe Science and Technology Co Ltd
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Beijing Zhongke Renhe Science and Technology Co Ltd
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Priority to CNA2008101045201A priority Critical patent/CN101259263A/en
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Abstract

The present invention discloses a medicine combination for remedying the stomach-heat damp obstructing type obesity and a preparation method thereof. The effective components of the present invention are extracted from more than ten kinds of medicinal materials of salvia, tuckahoe peel, ginger peel, tangerine peel, Indian bread pink epidermis, lilyturf, oriental waterplantain rhizome, largehead atractylode rhizome, white mulberry bark, common perilla, tangerine peel, villous amomum fruit, common aucklandia root, lotus leaf, etc. The specific medicinal active components of the present invention have the efficacies of clearing away heat to dissolve damp and catharsis and are used for remedying the patients with the stomach-heat damp obstructing type obesity with the symptoms of bitter taste in mouth, halitosis, easy hungriness, fidgety mood, yellowish urine and frequent constipation.

Description

A kind of drug regimen for the treatment of the gastric heat moisture resistance type obesity and preparation method thereof
Technical field
The invention belongs to technical field of traditional Chinese medicine pharmacy, be specifically related to a kind of drug regimen for the treatment of the gastric heat moisture resistance type obesity and preparation method thereof.
Technical background
Diet tea always is popular method of weight-reducing, but the diet tea of Chu Shouing not is to prepare at slimmer's body constitution on the market, drink if at will buy, be easy to generate problem, too many such as diarrhoea, digestion, absorption function can be undermined, cause health to eat more empty and more empty, and fat-reducing effect is also good inadequately.So Southeast Asia becomes more and more popular according to the health of oneself recently, look for Traditional Chinese Medicine experts to suit the remedy to the case and dispose Chinese herbal medicine weight reducing tea.Someone just reduced six or seven kilograms in one month!
Under the theory of traditional medicine " integration of edible and medicinal herbs ", character is gentle, and the medical material with health preserving, health care generally is eaten already, and as fashionable fat-reducing panacea Fructus Crataegi, Folium Nelumbinis etc., how these medical materials lose weight, and are determined by the doctor.The principle of Chinese traditional treatment obesity is to start the original function of health, after the recovery function originally, suitably gets into shape and loss of weight again, allows stature give original lines for change.
For overweight person, the traditional Chinese medical science is opened the fat-reducing prescription according to the origin cause of formation, body constitution etc., divides four big classes, the fat-reducing mode of having nothing in common with each other.This four big class comprises: gastric heat damp-obstruction type, insufficiency of the spleen damp-obstruction type, caused by hepatic stagnation qi stagnation and liver-kidney yin deficiency.
Statistics shows that the patient of gastric heat type and Qi-stagnation type is maximum, and the weight reducing treatments effect is also better, and there is the people in average 2 weeks even subtracted six or seven kilograms in one month with regard to thin 2 jin of energy.But the YIN-deficiency type patient more than 50 years old because metabolism own is poor, adds chronic disease and is burdened with, and fat-reducing effect is not obvious.
Gastric heat type patient: refer to that reason that the white collar below 30 years old is got fat is that dinner party is many, the diet heavy wool is bored with, operating pressure is big etc. more, cause intimate heat unnecessary, health is excited, easy bitter taste, halitosis, easily hunger, irritated, urine Huang, the love constipation partially of emotion, from the traditional Chinese medical science, except the fat that disappears, diuresis, key is heat clearing away, and it is normal that the body metabolism function just can be recovered.
The present invention is that theoretical basis develops at gastric heat moisture resistance type obesity patient in conjunction with the modern Chinese medicine pharmaceutical technology according to differentiation of tcm.
Summary of the invention:
One of purpose of the present invention provides a kind of drug regimen for the treatment of the gastric heat moisture resistance type obesity.
Another object of the present invention provides the preparation method of this drug regimen.
Chinese medicine of the present invention is made up of active ingredient and/or pharmaceutically acceptable carrier, and wherein said active ingredient is made (part is unit of weight) by following raw materials according:
1. write out a prescription
Radix Salviae Miltiorrhizae 100-300 part Cortex Sclerotii Poriae 100-300 part CORTEX ZINGIBERIS RHIZOMAE 100-200 part
The red Siberian cocklebur 100-200 of Pericarpium Citri Reticulatae 100-300 part part Radix Ophiopogonis 100-200 part
Rhizoma Alismatis 100-300 part Rhizoma Atractylodis Macrocephalae 100-200 part Cortex Mori 100-200 part
Folium Perillae 100-200 part Pericarpium Citri Reticulatae 100-200 part Fructus Amomi 100-200 part
Radix Aucklandiae 100-200 part Folium Nelumbinis 100-300 part
The active component that preferred following raw materials according is made, curative effect is better:
120 parts of 150 parts of CORTEX ZINGIBERIS RHIZOMAE of 150 parts of Cortex Sclerotii Poriae of Radix Salviae Miltiorrhizae
120 parts of 120 parts of Radix Ophiopogonis of 150 parts of red Siberian cockleburs of Pericarpium Citri Reticulatae
120 parts of 120 parts of Cortex Mori of 150 parts of Rhizoma Atractylodis Macrocephalaes of Rhizoma Alismatis
120 parts of 120 parts of Fructus Amomis of 120 parts of Pericarpium Citri Reticulataes of Folium Perillae
150 parts on 120 parts of Folium Nelumbinis of the Radix Aucklandiae
The active ingredient preparation method of Chinese medicine of the present invention can be that raw material is dry respectively, and levigation mixes.It also can be the conventional method preparation of adopting herbal pharmaceutical.These pharmacy conventional methods can be water extract-alcohol precipitation or ethanol extract from water precipitation, also have other extracting method in addition, specifically " pharmaceutics of Chinese drugs " published referring to Cao Chunlin chief editor's Shanghai science tech publishing house.
The following preparation method preparation of preferred employing:
2. preparation technology
(1) Radix Salviae Miltiorrhizae adds 80% alcohol dipping three times, floods 48 hours for the first time, and second and third time flooded respectively 24 hours, filters, and decompression filtrate recycling ethanol is condensed into the thick paste shape, and vacuum drying below 85 ℃ becomes dried cream;
(2) medical materials such as all the other Cortex Sclerotii Poriae, CORTEX ZINGIBERIS RHIZOMAE, Pericarpium Citri Reticulatae, red Siberian cocklebur, Radix Ophiopogonis, Rhizoma Alismatis, the Rhizoma Atractylodis Macrocephalae, Cortex Mori, Folium Perillae, Pericarpium Citri Reticulatae, Fructus Amomi, the Radix Aucklandiae, Folium Nelumbinis add 10 times of decoctings and boil three times, 1 hour for the first time, second and third time 0.5 hour, filter, merging filtrate, filtrate is condensed into the clear paste that relative density is 1.08~1.14 (50~60 ℃), add 2.8 times of amount ethanol, stir evenly, be heated to 60 ℃, left standstill 24 hours, filter, decompression filtrate recycling ethanol is condensed into the thick paste shape, and vacuum drying below 85 ℃ becomes dried cream;
(3) step (1) get dry extract is got dry extract with step (2) mix, be ground into fine powder, add acceptable accessories and make different preparations such as granule, sheet, capsule.
Adopt mutual compatibility of above-mentioned raw material of Chinese medicine and preparation method thereof, full side has the effect of clearing away heat and eliminating dampness purging FU-organs.Be used for the treatment of the gastric heat moisture resistance type obesity, the patient that disease is seen bitter taste, halitosis, easy hunger, emotion is irritated, urine is yellow partially, like constipation.
By the following examples technical scheme of the present invention is described further.
The specific embodiment
Embodiment 1: the preparation method of granule
1. write out a prescription
120 parts of 150 parts of CORTEX ZINGIBERIS RHIZOMAE of 150 parts of Cortex Sclerotii Poriae of Radix Salviae Miltiorrhizae
120 parts of 120 parts of Radix Ophiopogonis of 150 parts of red Siberian cockleburs of Pericarpium Citri Reticulatae
120 parts of 120 parts of Cortex Mori of 150 parts of Rhizoma Atractylodis Macrocephalaes of Rhizoma Alismatis
120 parts of 120 parts of Fructus Amomis of 120 parts of Pericarpium Citri Reticulataes of Folium Perillae
150 parts on 120 parts of Folium Nelumbinis of the Radix Aucklandiae
2. preparation technology
(1) Radix Salviae Miltiorrhizae adds 80% alcohol dipping three times, floods 48 hours for the first time, and second and third time flooded respectively 24 hours, filters, and decompression filtrate recycling ethanol is condensed into the thick paste shape, and vacuum drying below 85 ℃ becomes dried cream;
(2) medical materials such as all the other Cortex Sclerotii Poriae, CORTEX ZINGIBERIS RHIZOMAE, Pericarpium Citri Reticulatae, red Siberian cocklebur, Radix Ophiopogonis, Rhizoma Alismatis, the Rhizoma Atractylodis Macrocephalae, Cortex Mori, Folium Perillae, Pericarpium Citri Reticulatae, Fructus Amomi, the Radix Aucklandiae, Folium Nelumbinis add 10 times of decoctings and boil three times, 1 hour for the first time, second and third time 0.5 hour, filter, merging filtrate, filtrate is condensed into the clear paste that relative density is 1.08~1.14 (50~60 ℃), add 2.8 times of amount ethanol, stir evenly, be heated to 60 ℃, left standstill 24 hours, filter, decompression filtrate recycling ethanol is condensed into the thick paste shape, and vacuum drying below 85 ℃ becomes dried cream;
(3) step (1) get dry extract is got dry extract with step (2) mix, add cane sugar powder, mixing is made granule, drying, promptly.
Embodiment 2: the preparation method of tablet
1. write out a prescription
120 parts of 150 parts of CORTEX ZINGIBERIS RHIZOMAE of 150 parts of Cortex Sclerotii Poriae of Radix Salviae Miltiorrhizae
120 parts of 120 parts of Radix Ophiopogonis of 150 parts of red Siberian cockleburs of Pericarpium Citri Reticulatae
120 parts of 120 parts of Cortex Mori of 150 parts of Rhizoma Atractylodis Macrocephalaes of Rhizoma Alismatis
120 parts of 120 parts of Fructus Amomis of 120 parts of Pericarpium Citri Reticulataes of Folium Perillae
150 parts on 120 parts of Folium Nelumbinis of the Radix Aucklandiae
2. preparation technology
(1) Radix Salviae Miltiorrhizae adds 80% alcohol dipping three times, floods 48 hours for the first time, and second and third time flooded respectively 24 hours, filters, and decompression filtrate recycling ethanol is condensed into the thick paste shape, and vacuum drying below 85 ℃ becomes dried cream;
(2) medical materials such as all the other Cortex Sclerotii Poriae, CORTEX ZINGIBERIS RHIZOMAE, Pericarpium Citri Reticulatae, red Siberian cocklebur, Radix Ophiopogonis, Rhizoma Alismatis, the Rhizoma Atractylodis Macrocephalae, Cortex Mori, Folium Perillae, Pericarpium Citri Reticulatae, Fructus Amomi, the Radix Aucklandiae, Folium Nelumbinis add 10 times of decoctings and boil three times, 1 hour for the first time, second and third time 0.5 hour, filter, merging filtrate, filtrate is condensed into the clear paste that relative density is 1.08~1.14 (50~60 ℃), add 2.8 times of amount ethanol, stir evenly, be heated to 60 ℃, left standstill 24 hours, filter, decompression filtrate recycling ethanol is condensed into the thick paste shape, and vacuum drying below 85 ℃ becomes dried cream;
(3) step (1) get dry extract is got dry extract with step (2) mix, pulverize, sieve, add starch, magnesium stearate, tabletting, promptly.
Embodiment 3: the preparation method of capsule
1. write out a prescription
120 parts of 150 parts of CORTEX ZINGIBERIS RHIZOMAE of 150 parts of Cortex Sclerotii Poriae of Radix Salviae Miltiorrhizae
120 parts of 120 parts of Radix Ophiopogonis of 150 parts of red Siberian cockleburs of Pericarpium Citri Reticulatae
120 parts of 120 parts of Cortex Mori of 150 parts of Rhizoma Atractylodis Macrocephalaes of Rhizoma Alismatis
120 parts of 120 parts of Fructus Amomis of 120 parts of Pericarpium Citri Reticulataes of Folium Perillae
150 parts on 120 parts of Folium Nelumbinis of the Radix Aucklandiae
2. preparation technology
(1) Radix Salviae Miltiorrhizae adds 80% alcohol dipping three times, floods 48 hours for the first time, and second and third time flooded respectively 24 hours, filters, and decompression filtrate recycling ethanol is condensed into the thick paste shape, and vacuum drying below 85 ℃ becomes dried cream;
(2) medical materials such as all the other Cortex Sclerotii Poriae, CORTEX ZINGIBERIS RHIZOMAE, Pericarpium Citri Reticulatae, red Siberian cocklebur, Radix Ophiopogonis, Rhizoma Alismatis, the Rhizoma Atractylodis Macrocephalae, Cortex Mori, Folium Perillae, Pericarpium Citri Reticulatae, Fructus Amomi, the Radix Aucklandiae, Folium Nelumbinis add 10 times of decoctings and boil three times, 1 hour for the first time, second and third time 0.5 hour, filter, merging filtrate, filtrate is condensed into the clear paste that relative density is 1.08~1.14 (50~60 ℃), add 2.8 times of amount ethanol, stir evenly, be heated to 60 ℃, left standstill 24 hours, filter, decompression filtrate recycling ethanol is condensed into the thick paste shape, and vacuum drying below 85 ℃ becomes dried cream;
(3) step (1) get dry extract is got dry extract with step (2) mix, pulverize, sieve, add starch, mixing is made granule, and drying incapsulates, promptly.

Claims (5)

1, a kind of drug regimen for the treatment of the gastric heat moisture resistance type obesity is characterized in that being made up of active ingredient and/or pharmaceutically acceptable carrier, and wherein said active ingredient is made by following raw materials according:
Radix Salviae Miltiorrhizae 100-300 part Cortex Sclerotii Poriae 100-300 part CORTEX ZINGIBERIS RHIZOMAE 100-200 part
The red Siberian cocklebur 100-200 of Pericarpium Citri Reticulatae 100-300 part part Radix Ophiopogonis 100-200 part
Rhizoma Alismatis 100-300 part Rhizoma Atractylodis Macrocephalae 100-200 part Cortex Mori 100-200 part
Folium Perillae 100-200 part Pericarpium Citri Reticulatae 100-200 part Fructus Amomi 100-200 part
Radix Aucklandiae 100-200 part Folium Nelumbinis 100-300 part
2, a kind of drug regimen for the treatment of the gastric heat moisture resistance type obesity according to claim 1 is characterized in that wherein preparing the preferred following raw materials according of described active ingredient:
120 parts of 150 parts of CORTEX ZINGIBERIS RHIZOMAE of 150 parts of Cortex Sclerotii Poriae of Radix Salviae Miltiorrhizae
120 parts of 120 parts of Radix Ophiopogonis of 150 parts of red Siberian cockleburs of Pericarpium Citri Reticulatae
120 parts of 120 parts of Cortex Mori of 150 parts of Rhizoma Atractylodis Macrocephalaes of Rhizoma Alismatis
120 parts of 120 parts of Fructus Amomis of 120 parts of Pericarpium Citri Reticulataes of Folium Perillae
150 parts on 120 parts of Folium Nelumbinis of the Radix Aucklandiae
3, according to the described a kind of drug regimen for the treatment of the gastric heat moisture resistance type obesity of claim 1-2, it is characterized in that adopting following method to make:
(1) Radix Salviae Miltiorrhizae adds 80% alcohol dipping three times, floods 48 hours for the first time, and second and third time flooded respectively 24 hours, filters, and decompression filtrate recycling ethanol is condensed into the thick paste shape, and vacuum drying below 85 ℃ becomes dried cream;
(2) medical materials such as all the other Cortex Sclerotii Poriae, CORTEX ZINGIBERIS RHIZOMAE, Pericarpium Citri Reticulatae, red Siberian cocklebur, Radix Ophiopogonis, Rhizoma Alismatis, the Rhizoma Atractylodis Macrocephalae, Cortex Mori, Folium Perillae, Pericarpium Citri Reticulatae, Fructus Amomi, the Radix Aucklandiae, Folium Nelumbinis add 10 times of decoctings and boil three times, 1 hour for the first time, second and third time 0.5 hour, filter, merging filtrate, filtrate is condensed into the clear paste that relative density is 1.08~1.14 (50~60 ℃), add 2.8 times of amount ethanol, stir evenly, be heated to 60 ℃, left standstill 24 hours, filter, decompression filtrate recycling ethanol is condensed into the thick paste shape, and vacuum drying below 85 ℃ becomes dried cream;
(3) step (1) get dry extract is got dry extract with step (2) mix, be ground into fine powder, add acceptable accessories and make different preparations such as granule, sheet, capsule.
4, according to any one described a kind of drug regimen for the treatment of the gastric heat moisture resistance type obesity among the claim 1-3, it is characterized in that this Chinese medicine composition is an oral formulations.
5, according to the described a kind of drug regimen for the treatment of the gastric heat moisture resistance type obesity of claim 3-4, it is characterized in that this Chinese medicine composition can be made into granule, capsule, tablet.
CNA2008101045201A 2008-04-21 2008-04-21 Medicaments assembly for treating stomach-heat moisture resistance type obesity and preparation thereof Pending CN101259263A (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106474452A (en) * 2016-12-31 2017-03-08 湖南灼华生物科技有限公司 For improving Chinese medicine composition and the preparation method and applications of halitosis
CN113230349A (en) * 2021-06-30 2021-08-10 浙江省人民医院 A Chinese medicinal composition for treating obesity, and its preparation method

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106474452A (en) * 2016-12-31 2017-03-08 湖南灼华生物科技有限公司 For improving Chinese medicine composition and the preparation method and applications of halitosis
CN113230349A (en) * 2021-06-30 2021-08-10 浙江省人民医院 A Chinese medicinal composition for treating obesity, and its preparation method

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Open date: 20080910