CN101530599A - A pharmaceutical composition for treating mental depression - Google Patents
A pharmaceutical composition for treating mental depression Download PDFInfo
- Publication number
- CN101530599A CN101530599A CN200910130917A CN200910130917A CN101530599A CN 101530599 A CN101530599 A CN 101530599A CN 200910130917 A CN200910130917 A CN 200910130917A CN 200910130917 A CN200910130917 A CN 200910130917A CN 101530599 A CN101530599 A CN 101530599A
- Authority
- CN
- China
- Prior art keywords
- weight portion
- weight
- radix
- pharmaceutical composition
- portions
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Medicines Containing Plant Substances (AREA)
Abstract
The invention relates to a pharmaceutical composition for treating mental depression, which is prepared by angelica, Szechuan Lovage Rhizome, grass-leaved sweetflag, radix curcumae, Morinda officinalis, liquorice, Tuckahoe, wild jujube, radix paeoniae alba, dried tangerine peel, citrus aurantium, forsythia, tuber pinellia, Flos Albiziae, and radix bupleuri. The pharmaceutical composition for treating mental depression has the advantages of reasonable prescription, simple and easily-achieved components, remarkable curative effect and no obvious side effect.
Description
Technical field
The present invention relates to field of medicaments, particularly, the present invention relates to the dysthymic pharmaceutical composition of a kind of treatment.
Background technology
Spirit depressing is one of mental disorder the most common among the crowd.Survey result according to The World Health Organization (WHO) shows that whole world depression sickness rate is about 3.1%.At present, along with the quickening of social rhythm and the increasing of modern's life pressure, depression also begins to present the trend of being on the increase.And a trend that increases newly of depression is that the patient's age distribution broadens, and a lot of youngsters also begin to suffer from depression.And according to relevant report, the sickness rate of depression in crowd more than 60 years old will be up to 20%-50%.It is predicted that these national depression sickness rate can be brought up to about 8%-10% 2005." World Health Report in 2002 " that World Health Organization (WHO) delivers points out that depression has become the fourth-largest illness in the world at present, may become to the year two thousand twenty depression to be only second to cardiopathic second largest disease.
The medicine of depression mostly is chemicals greatly at present.But because depression is a kind of spiritual class disease, the cause of disease is very complicated.When using chemotherapy, improper use not only can not treated depression, may aggravate one's illness or be converted into other spiritual class diseases on the contrary.Therefore, do not interrupt for the research of the medicine of new treatment depression always.
Chinese medicine thinks, depression is that feelings will is smooth, the class disease due to the depression and stagnation of QI, and excessive thinking, damage vital essence (blood) are main inducing.Common clinically differentiation of symptoms and signs for classification of syndrome has stagnation of QI due to depression of the liver, mental disorder pent-up, deficiency of both the heart and spleen, deficiency of the liver and kindey and YIN-deficiency of both the heart and lung etc.; Method of treatment is respectively a depressed liver-energy dispersing and QI regulating, the dissipating depression of QI that reduces phlegm, invigorating the heart and spleen, nourishing the liver and kidney and YIN nourishing tonifying the lung.And Chinese medicine has the little unique advantage of side effect, therefore very is necessary to develop the dysthymic pharmaceutical composition of a kind of treatment.
Summary of the invention
The purpose of this invention is to provide the dysthymic pharmaceutical composition of a kind of treatment.
In order to realize purpose of the present invention, the invention provides the dysthymic pharmaceutical composition of a kind of treatment, it is the medicament of being made according to weight proportion by following ingredients:
Radix Angelicae Sinensis 3～10 weight portion Rhizoma Chuanxiongs 2～6 weight portion Rhizoma Acori Graminei 10～20 weight portions
Radix Curcumae 3～10 weight portion Radix Morindae Officinaliss 3～10 weight portion Radix Glycyrrhizaes 1～10 weight portion
Poria 1～3 weight portion Semen Ziziphi Spinosae 3～10 weight portion Radix Paeoniae Albas 1～20 weight portion
Pericarpium Citri Reticulatae 1～10 weight portion Fructus Aurantii Immaturus 2～6 weight portion Fructus Forsythiaes 5～10 weight portions
The Rhizoma Pinelliae 3～10 weight portion Flos Albiziaes 1～5 weight portion Radix Bupleuri 2～6 weight portions.
Preferably, the dysthymic pharmaceutical composition of treatment of the present invention is by following one-tenth
Divide the medicament of making according to weight proportion:
Radix Angelicae Sinensis 7 weight portion Rhizoma Chuanxiongs 3 weight portion Rhizoma Acori Graminei 15 weight portions
Radix Curcumae 5 weight portion Radix Morindae Officinaliss 3 weight portion Radix Glycyrrhizaes 8 weight portions
The Poria 2 weight portion Semen Ziziphi Spinosaes 5 weight portion Radix Paeoniae Albas 10 weight portions
Pericarpium Citri Reticulatae 7 weight portion Fructus Aurantii Immaturuss 4 weight portion Fructus Forsythiaes 7 weight portions
The Rhizoma Pinelliae 5 weight portion Flos Albiziaes 5 weight portion Radix Bupleuri 3 weight portions.
The dysthymic pharmaceutical composition of treatment of the present invention can be made various dosage forms according to technological means well-known to those skilled in the art, for example tablet (dispersible tablet), capsule, (hard capsule), decoction etc.
The dysthymic drug regimen composition formula of treatment of the present invention is reasonable, and composition is simple and easy to, and is evident in efficacy, and do not have significant side effects.
The specific embodiment
The following examples will give further instruction to the present invention, but not thereby limiting the invention.
Embodiment 1
Get Radix Angelicae Sinensis 7 gram, Rhizoma Chuanxiong 3 grams, Rhizoma Acori Graminei 15 grams, Radix Curcumae 5 grams, Radix Morindae Officinalis 3 grams, Radix Glycyrrhizae 8 grams, Poria 2 grams, Semen Ziziphi Spinosae 5 grams, the Radix Paeoniae Alba 10 grams, Pericarpium Citri Reticulatae 7 grams, Fructus Aurantii Immaturus 4 grams, Fructus Forsythiae 7 grams, the Rhizoma Pinelliae 5 grams, Flos Albiziae 5 grams, Radix Bupleuri 3 grams and place the round-bottomed flask that has distilling apparatus, add 200 ml waters, reflux 3 hours, cooling is filtered promptly.
Embodiment 2
Get Radix Angelicae Sinensis 7 grams, Rhizoma Chuanxiong 3 grams, Rhizoma Acori Graminei 15 grams, Radix Curcumae 5 grams, Radix Morindae Officinalis 3 grams, Radix Glycyrrhizae 8 grams, Poria 2 grams, Semen Ziziphi Spinosae 5 grams, the Radix Paeoniae Alba 10 grams, Pericarpium Citri Reticulatae 7 grams, Fructus Aurantii Immaturus 4 grams, Fructus Forsythiae 7 grams, the Rhizoma Pinelliae 5 grams, Flos Albiziae 5 grams, Radix Bupleuri 3 grams, pulverized 80 mesh sieves, add 150 gram Icing Sugar, amidin pelletize with 8% is in 100 No. 4 capsule shells of packing into.
The test example
The test standard of depression: " International Classification of Diseases-Di ten editions " that announces according to WHO and APA,American Psychiatric Association " mental disorder Diagnostic Statistical Manual-Di four editions " and the classification of Chinese mental disorder are diagnosed depression with the diagnostic criteria third edition (CCMD-3) about the diagnostic criteria of depression, and the eliminating organic disease.Depressed degree is according to Hamilton depressive scale (HAMD) scoring (totally 24), wherein＜8 is divided into normally, and 8～18 are divided into slight depression, and 18～24 are divided into the moderate depression,〉24 be divided into severe depression.The HAMD scoring is referring to " psychiatric department evaluation scale " [M]. Changsha: Hunan science and technology publishing house, 1993, the 122～203 pages.
Patient's situation: male 18 examples, 36.3 ± 3 years old mean age; Woman's 14 examples, 38.1 ± 4 years old mean age.
Therapeutic Method:
Treatment group: prepare decoction according to embodiment 1 described mode.Each 2 times, each oral above-mentioned decoction that makes.Continuous 4 weeks.
Matched group: oral fluoxetine (gift comes) 20mg/ day, continuous 4 weeks.
Observation index: the HAMD scoring before and after the test of record group respectively.To subtract the branch rate〉75% be clinical recovery, be marked improvement to subtract branch rate 〉=50%, be progress to subtract branch rate 〉=30%, be invalid with＜30%.
Therapeutic outcome:
Before the treatment: the HAMD scoring of treatment group and matched group is 25, and the preceding two groups of indifferences of treatment are described.
The treatment back: the HAMD scoring of treatment group is 6, and subtracting the branch rate is 76%; The HAMD scoring of matched group is 9, and subtracting the branch rate is 64%.Illustrate that both all can be used as the medicine of clinical treatment depression, and the effect of treatment group is better than the effect of matched group.
Untoward reaction: after therapeutic process and the treatment, all find no any discomfort in the treatment group, have 1 routine patient vomiting to occur, feel sick in the matched group, headache appears in 2 routine patients.
Claims (3)
1. treat dysthymic pharmaceutical composition for one kind, it is characterized in that it is the medicament of being made according to weight proportion by following ingredients:
Radix Angelicae Sinensis 3～10 weight portion Rhizoma Chuanxiongs 2～6 weight portion Rhizoma Acori Graminei 10～20 weight portions
Radix Curcumae 3～10 weight portion Radix Morindae Officinaliss 3～10 weight portion Radix Glycyrrhizaes 1～10 weight portion
Poria 1～3 weight portion Semen Ziziphi Spinosae 3～10 weight portion Radix Paeoniae Albas 1～20 weight portion
Pericarpium Citri Reticulatae 1～10 weight portion Fructus Aurantii Immaturus 2～6 weight portion Fructus Forsythiaes 5～10 weight portions
The Rhizoma Pinelliae 3～10 weight portion Flos Albiziaes 1～5 weight portion Radix Bupleuri 2～6 weight portions.
2. the dysthymic pharmaceutical composition of treatment according to claim 1 is characterized in that, it is the medicament of being made according to weight proportion by following ingredients:
Radix Angelicae Sinensis 7 weight portion Rhizoma Chuanxiongs 3 weight portion Rhizoma Acori Graminei 15 weight portions
Radix Curcumae 5 weight portion Radix Morindae Officinaliss 3 weight portion Radix Glycyrrhizaes 8 weight portions
The Poria 2 weight portion Semen Ziziphi Spinosaes 5 weight portion Radix Paeoniae Albas 10 weight portions
Pericarpium Citri Reticulatae 7 weight portion Fructus Aurantii Immaturuss 4 weight portion Fructus Forsythiaes 7 weight portions
The Rhizoma Pinelliae 5 weight portion Flos Albiziaes 5 weight portion Radix Bupleuri 3 weight portions.
3. the dysthymic pharmaceutical composition of treatment according to claim 1 and 2 is characterized in that described medicament is tablet, dispersible tablet, capsule, hard capsule, decoction.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2009101309172A CN101530599B (en) | 2009-04-20 | 2009-04-20 | A pharmaceutical composition for treating mental depression |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2009101309172A CN101530599B (en) | 2009-04-20 | 2009-04-20 | A pharmaceutical composition for treating mental depression |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN101530599A true CN101530599A (en) | 2009-09-16 |
| CN101530599B CN101530599B (en) | 2010-12-01 |
Family
ID=41101596
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2009101309172A Expired - Fee Related CN101530599B (en) | 2009-04-20 | 2009-04-20 | A pharmaceutical composition for treating mental depression |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN101530599B (en) |
Cited By (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101856483A (en) * | 2010-06-30 | 2010-10-13 | 泰一和浦（北京）中医药研究院有限公司 | Chinese medicinal composition for treating intermenstrual abnormal emotion and preparation method thereof |
| CN102198253A (en) * | 2011-05-27 | 2011-09-28 | 上海市中医医院 | Traditional Chinese medicine composition for resisting depression, and preparation method as well as application thereof |
| CN102233071A (en) * | 2010-04-21 | 2011-11-09 | 中国中医科学院广安门医院 | Traditional Chinese medicine composition for treating depression and preparation method thereof |
| CN102327557A (en) * | 2011-09-10 | 2012-01-25 | 田开勇 | Anxiety-removing calming traditional Chinese medicine decoction for treating anxiety neurosis |
| CN102406917A (en) * | 2011-11-29 | 2012-04-11 | 北京阜康仁生物制药科技有限公司 | Antidepressive traditional Chinese medicine composition and preparation method thereof |
| CN103041351A (en) * | 2012-12-31 | 2013-04-17 | 王彬 | Decoction for treating dysthymia |
| CN103933487A (en) * | 2014-05-09 | 2014-07-23 | 厦门大学 | Compound traditional Chinese medicament for treating depression |
| CN104383449A (en) * | 2014-11-28 | 2015-03-04 | 邹士东 | Pharmaceutical composition for treating depression syndrome |
| CN104435428A (en) * | 2014-11-29 | 2015-03-25 | 黄根强 | Traditional Chinese medicine composition for treating depression |
| CN104645246A (en) * | 2015-03-15 | 2015-05-27 | 陈明友 | Pharmaceutical preparation for treating female menopausal depression |
| CN105582480A (en) * | 2016-03-03 | 2016-05-18 | 林炜 | Traditional Chinese medicine composition for treating depression |
| CN105582479A (en) * | 2016-03-03 | 2016-05-18 | 林炜 | Preparation method of traditional Chinese medicine composition for treating depression |
| CN105617279A (en) * | 2016-03-03 | 2016-06-01 | 林炜 | Preparation method of traditional Chinese medicine for treating depression |
| CN105688070A (en) * | 2016-03-14 | 2016-06-22 | 陈霞 | Medicine composition for treating postpartum depression |
| CN109077349A (en) * | 2018-08-28 | 2018-12-25 | 河北中烟工业有限责任公司 | Have effects that the composition of antidepression and preparation process and the application in electronics tobacco tar |
-
2009
- 2009-04-20 CN CN2009101309172A patent/CN101530599B/en not_active Expired - Fee Related
Cited By (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102233071A (en) * | 2010-04-21 | 2011-11-09 | 中国中医科学院广安门医院 | Traditional Chinese medicine composition for treating depression and preparation method thereof |
| CN102233071B (en) * | 2010-04-21 | 2013-02-06 | 中国中医科学院广安门医院 | Traditional Chinese medicine composition for treating depression and preparation method thereof |
| CN101856483A (en) * | 2010-06-30 | 2010-10-13 | 泰一和浦（北京）中医药研究院有限公司 | Chinese medicinal composition for treating intermenstrual abnormal emotion and preparation method thereof |
| CN102198253A (en) * | 2011-05-27 | 2011-09-28 | 上海市中医医院 | Traditional Chinese medicine composition for resisting depression, and preparation method as well as application thereof |
| CN102198253B (en) * | 2011-05-27 | 2012-09-05 | 上海市中医医院 | Traditional Chinese medicine composition for resisting depression, and preparation method as well as application thereof |
| CN102327557A (en) * | 2011-09-10 | 2012-01-25 | 田开勇 | Anxiety-removing calming traditional Chinese medicine decoction for treating anxiety neurosis |
| CN102406917A (en) * | 2011-11-29 | 2012-04-11 | 北京阜康仁生物制药科技有限公司 | Antidepressive traditional Chinese medicine composition and preparation method thereof |
| CN103041351A (en) * | 2012-12-31 | 2013-04-17 | 王彬 | Decoction for treating dysthymia |
| CN103933487A (en) * | 2014-05-09 | 2014-07-23 | 厦门大学 | Compound traditional Chinese medicament for treating depression |
| CN104383449A (en) * | 2014-11-28 | 2015-03-04 | 邹士东 | Pharmaceutical composition for treating depression syndrome |
| CN104383449B (en) * | 2014-11-28 | 2015-07-08 | 刘浩志 | Pharmaceutical composition for treating depression syndrome |
| CN104435428A (en) * | 2014-11-29 | 2015-03-25 | 黄根强 | Traditional Chinese medicine composition for treating depression |
| CN104645246A (en) * | 2015-03-15 | 2015-05-27 | 陈明友 | Pharmaceutical preparation for treating female menopausal depression |
| CN104645246B (en) * | 2015-03-15 | 2017-12-01 | 倪瑞云 | A kind of pharmaceutical preparation depressed for Menopause |
| CN105582480A (en) * | 2016-03-03 | 2016-05-18 | 林炜 | Traditional Chinese medicine composition for treating depression |
| CN105582479A (en) * | 2016-03-03 | 2016-05-18 | 林炜 | Preparation method of traditional Chinese medicine composition for treating depression |
| CN105617279A (en) * | 2016-03-03 | 2016-06-01 | 林炜 | Preparation method of traditional Chinese medicine for treating depression |
| CN105688070A (en) * | 2016-03-14 | 2016-06-22 | 陈霞 | Medicine composition for treating postpartum depression |
| CN109077349A (en) * | 2018-08-28 | 2018-12-25 | 河北中烟工业有限责任公司 | Have effects that the composition of antidepression and preparation process and the application in electronics tobacco tar |
Also Published As
| Publication number | Publication date |
|---|---|
| CN101530599B (en) | 2010-12-01 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN101530599B (en) | A pharmaceutical composition for treating mental depression | |
| CN101204575B (en) | Chinese traditional medicine composite for depressive neurosis, preparation method and application thereof | |
| CN101524524A (en) | Drug for treating severe cold and preparation method thereof | |
| CN102205090B (en) | Chinese medicinal stagnancy-removing and stagnation-eliminating soup for treating liver depression qi stagnation type indigestion | |
| CN101711847B (en) | Oral traditional Chinese medicine preparation for treating melancholia and anxiety neurosis | |
| CN102631579B (en) | Oral Chinese herbal preparation for treating post-traumatic brain syndrome | |
| CN104352608A (en) | Traditional Chinese medicine capable of benefiting qi, activating blood circulation, softening hardness, dissipating stagnation, realizing detoxification and relieving pain as well as preparation method thereof | |
| CN102000271A (en) | Oral medicament for removing acne | |
| CN102078462A (en) | Asthma relieving medicament | |
| CN105641419A (en) | Traditional Chinese medicine composition for treating Yin deficiency type cough caused by lung cancer | |
| CN105147866A (en) | Traditional Chinese medicine composition for improving cerebral circulation and atherosclerosis and application thereof | |
| CN103877376B (en) | A kind of pharmaceutical preparation treating depression | |
| CN106237268A (en) | One treats schizoid pharmaceutical composition and application thereof | |
| CN101708300A (en) | Medicinal composition for treating scrofula, hyperplasia of mammary glands and benign lymphadenoma | |
| CN102416147B (en) | Medicinal composition for treating mania of patients abstained from drugs | |
| CN104436049A (en) | Traditional Chinese medicine composition for treating heart disease | |
| CN102805795B (en) | Chinese medicinal composition for treating acute soft tissue injury of chest and hypochondrium and application thereof | |
| CN108635457A (en) | A kind of Chinese medicine composition and the preparation method and application thereof for treating constipation | |
| CN103301368A (en) | Medicament for treating hyperactivity | |
| CN101829213B (en) | Medicine composition for treating asthma and preparation method thereof | |
| CN101288683A (en) | Application of roselle for preparing health product for promoting lead-eliminating effect | |
| CN105435047A (en) | Traditional Chinese medicine composition for treating primary hypertension and application thereof | |
| CN104645246A (en) | Pharmaceutical preparation for treating female menopausal depression | |
| CN104888068A (en) | Medicine for treatment or adjuvant treatment of acquired immune deficiency syndrome and preparation method and application method of medicine | |
| CN104800599A (en) | Traditional Chinese medicinal composition for treating deficiency of kidney-yin |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| C17 | Cessation of patent right | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20101201 Termination date: 20110420 |