CN101516393A - 热处理菌苗和由该热处理菌苗制备的乳液疫苗 - Google Patents
热处理菌苗和由该热处理菌苗制备的乳液疫苗 Download PDFInfo
- Publication number
- CN101516393A CN101516393A CNA2007800337672A CN200780033767A CN101516393A CN 101516393 A CN101516393 A CN 101516393A CN A2007800337672 A CNA2007800337672 A CN A2007800337672A CN 200780033767 A CN200780033767 A CN 200780033767A CN 101516393 A CN101516393 A CN 101516393A
- Authority
- CN
- China
- Prior art keywords
- vaccine
- heat treatment
- leptospira
- virus
- lipase active
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/0225—Spirochetes, e.g. Treponema, Leptospira, Borrelia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/12—Antidiarrhoeals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/52—Bacterial cells; Fungal cells; Protozoal cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55566—Emulsions, e.g. Freund's adjuvant, MF59
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55577—Saponins; Quil A; QS21; ISCOMS
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Immunology (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Communicable Diseases (AREA)
- Engineering & Computer Science (AREA)
- Oncology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Virology (AREA)
- Dispersion Chemistry (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicinal Preparation (AREA)
- Enzymes And Modification Thereof (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Abstract
Description
存储温度(12小时) | 4℃ | 37℃ | 45℃ | 56℃ | 65℃ | 80℃ |
原始脂肪酶活性百分比 | 100% | 55.4% | 32.5% | 15.7% | 10.8% | 8.4% |
组分 | 组分浓度/剂量 |
犬钩端螺旋体 | 1200NU/5ml剂量 |
出血黄疸钩端螺旋体 | 1200NU/5ml剂量 |
流感伤寒钩端螺旋体 | 1200NU/5ml剂量 |
哈德焦钩端螺旋体 | 2400NU/5ml剂量 |
波摩那钩端螺旋体 | 1200NU/5ml剂量 |
Claims (22)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US84366506P | 2006-09-11 | 2006-09-11 | |
US60/843,665 | 2006-09-11 | ||
PCT/IB2007/002553 WO2008032158A2 (en) | 2006-09-11 | 2007-08-30 | Heat treated bacterins, and emulsion vaccines prepared from such heat treated bacterins |
Publications (2)
Publication Number | Publication Date |
---|---|
CN101516393A true CN101516393A (zh) | 2009-08-26 |
CN101516393B CN101516393B (zh) | 2014-05-14 |
Family
ID=39110574
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN200780033767.2A Active CN101516393B (zh) | 2006-09-11 | 2007-08-30 | 热处理菌苗和由该热处理菌苗制备的乳液疫苗 |
Country Status (27)
Country | Link |
---|---|
US (1) | US8491915B2 (zh) |
EP (2) | EP2377550B1 (zh) |
JP (2) | JP5550341B2 (zh) |
KR (1) | KR101238486B1 (zh) |
CN (1) | CN101516393B (zh) |
AR (1) | AR062758A1 (zh) |
AU (1) | AU2007297287B2 (zh) |
BR (1) | BRPI0716548B1 (zh) |
CA (1) | CA2663166C (zh) |
CL (1) | CL2007002621A1 (zh) |
CO (1) | CO6160333A2 (zh) |
DK (2) | DK2066340T3 (zh) |
ES (2) | ES2432392T3 (zh) |
HK (1) | HK1130202A1 (zh) |
ME (1) | ME00598B (zh) |
MX (1) | MX2009001849A (zh) |
NO (1) | NO339147B1 (zh) |
NZ (2) | NZ574896A (zh) |
PL (2) | PL2377550T3 (zh) |
PT (1) | PT2066340E (zh) |
RS (1) | RS54981B1 (zh) |
RU (2) | RU2425692C2 (zh) |
SI (1) | SI2066340T1 (zh) |
TW (1) | TWI361077B (zh) |
UA (1) | UA98115C2 (zh) |
WO (1) | WO2008032158A2 (zh) |
ZA (1) | ZA200902493B (zh) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101903041A (zh) * | 2007-12-21 | 2010-12-01 | 辉瑞大药厂 | 经热处理的菌苗,及由这些经热处理的菌苗制备的乳剂疫苗 |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP2717055A1 (en) * | 2012-10-04 | 2014-04-09 | Institut Pasteur | Use of Leptospira fainei serovar Hurstbridge bacteria for diagnosing leptospirosis |
JP2024510057A (ja) * | 2020-05-26 | 2024-03-06 | サイラス トェンティファースト センチュリー アントレプレナーシップ エルエルシー | ハキムプールシナの除染手順 |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3721169A1 (de) * | 1986-06-30 | 1988-01-14 | Lion Corp | Orale zubereitung |
US5084269A (en) | 1986-11-06 | 1992-01-28 | Kullenberg Fred W | Adjuvant for dose treatment with antigens |
US6248329B1 (en) * | 1998-06-01 | 2001-06-19 | Ramaswamy Chandrashekar | Parasitic helminth cuticlin nucleic acid molecules and uses thereof |
AU2001234616A1 (en) | 2000-01-31 | 2001-08-07 | Vic Jira | Vaccine composition, process and methods |
US20030147914A1 (en) | 2001-07-02 | 2003-08-07 | Pfizer Inc. | Mycoplasma bovis vaccine and methods of reducing pneumonia in animals |
CA2496750C (en) | 2002-08-26 | 2014-10-21 | Pfizer Products Inc. | Vaccine for respiratory and reproductive system infections in cattle |
EP1549135A4 (en) | 2002-09-20 | 2006-01-11 | Us Agriculture | VACCINE AND ADJUVANT COMPOSITIONS |
AU2002951692A0 (en) | 2002-09-23 | 2002-10-17 | Vital Biotech (Hong Kong) Limited | Improvements in or relating to vaccines |
KR20050103215A (ko) * | 2003-01-29 | 2005-10-27 | 화이자 프로덕츠 인코포레이티드 | 보르데텔라 브론키셉티카에 대한 개 백신 |
PT1613346E (pt) * | 2003-04-04 | 2013-01-29 | Pah Usa 15 Llc | Emulsões óleo-em-água microfluidificadas e composições de vacinas |
-
2007
- 2007-08-30 RS RS20090088A patent/RS54981B1/sr unknown
- 2007-08-30 KR KR1020097004968A patent/KR101238486B1/ko active IP Right Grant
- 2007-08-30 MX MX2009001849A patent/MX2009001849A/es active IP Right Grant
- 2007-08-30 EP EP11173797.9A patent/EP2377550B1/en active Active
- 2007-08-30 JP JP2009527907A patent/JP5550341B2/ja active Active
- 2007-08-30 DK DK07804880.8T patent/DK2066340T3/da active
- 2007-08-30 NZ NZ574896A patent/NZ574896A/en unknown
- 2007-08-30 SI SI200731337T patent/SI2066340T1/sl unknown
- 2007-08-30 WO PCT/IB2007/002553 patent/WO2008032158A2/en active Application Filing
- 2007-08-30 PL PL11173797T patent/PL2377550T3/pl unknown
- 2007-08-30 EP EP07804880.8A patent/EP2066340B1/en active Active
- 2007-08-30 ES ES07804880T patent/ES2432392T3/es active Active
- 2007-08-30 DK DK11173797T patent/DK2377550T3/en active
- 2007-08-30 PL PL07804880T patent/PL2066340T3/pl unknown
- 2007-08-30 ME MEP-2009-75A patent/ME00598B/me unknown
- 2007-08-30 ES ES11173797.9T patent/ES2535977T3/es active Active
- 2007-08-30 PT PT78048808T patent/PT2066340E/pt unknown
- 2007-08-30 CN CN200780033767.2A patent/CN101516393B/zh active Active
- 2007-08-30 RU RU2009108004/10A patent/RU2425692C2/ru active
- 2007-08-30 UA UAA200902099A patent/UA98115C2/ru unknown
- 2007-08-30 BR BRPI0716548-0A patent/BRPI0716548B1/pt active IP Right Grant
- 2007-08-30 CA CA2663166A patent/CA2663166C/en active Active
- 2007-08-30 AU AU2007297287A patent/AU2007297287B2/en active Active
- 2007-08-30 NZ NZ595748A patent/NZ595748A/xx unknown
- 2007-09-07 US US11/851,951 patent/US8491915B2/en active Active
- 2007-09-10 TW TW096133683A patent/TWI361077B/zh active
- 2007-09-10 CL CL200702621A patent/CL2007002621A1/es unknown
- 2007-09-11 AR ARP070104028A patent/AR062758A1/es not_active Application Discontinuation
-
2009
- 2009-02-16 NO NO20090745A patent/NO339147B1/no unknown
- 2009-03-10 CO CO09024344A patent/CO6160333A2/es unknown
- 2009-04-09 ZA ZA200902493A patent/ZA200902493B/xx unknown
- 2009-10-08 HK HK09109330.1A patent/HK1130202A1/zh unknown
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2011
- 2011-04-20 RU RU2011115400/10A patent/RU2569457C2/ru active
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2014
- 2014-01-14 JP JP2014004122A patent/JP5643906B2/ja active Active
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101903041A (zh) * | 2007-12-21 | 2010-12-01 | 辉瑞大药厂 | 经热处理的菌苗,及由这些经热处理的菌苗制备的乳剂疫苗 |
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