CN101500595A - 组合治疗 - Google Patents
组合治疗 Download PDFInfo
- Publication number
- CN101500595A CN101500595A CNA2007800295078A CN200780029507A CN101500595A CN 101500595 A CN101500595 A CN 101500595A CN A2007800295078 A CNA2007800295078 A CN A2007800295078A CN 200780029507 A CN200780029507 A CN 200780029507A CN 101500595 A CN101500595 A CN 101500595A
- Authority
- CN
- China
- Prior art keywords
- pyridylmethyl
- methyl
- tetrahydrochysene
- benzene dimethylamine
- quinolyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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- A—HUMAN NECESSITIES
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Landscapes
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| CN105431521A (zh) * | 2013-02-28 | 2016-03-23 | 哈佛学院校长同事会 | 用于动员干细胞的方法和组合物 |
| CN111712262A (zh) * | 2017-12-06 | 2020-09-25 | 美真达治疗公司 | 用于动员造血干细胞和祖细胞的给药方案 |
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| CN101631850B (zh) * | 2007-01-09 | 2013-12-04 | 克里夫兰生物实验室公司 | 增加和转移造血干细胞的方法 |
| EP2262494A2 (en) * | 2008-02-29 | 2010-12-22 | The Board Of Trustees Of The Leland Stanford Junior University | Inhibition of post-radiation tumor growth by an inhibitor of vasculogenesis |
| US10813917B2 (en) * | 2009-12-11 | 2020-10-27 | Medregen, Llc | Treatment methods utilizing stem cell mobilizers and immunosuppressive agents |
| WO2011119738A2 (en) | 2010-03-23 | 2011-09-29 | The Johns Hopkins University | Methods of treatment using stem cell mobilizers |
| US8546353B2 (en) | 2010-05-06 | 2013-10-01 | Glykos Finland Oy | Compounds and combinations |
| EP2384759A1 (en) | 2010-05-06 | 2011-11-09 | Suomen Punainen Risti Veripalvelu | Sulphated hyaluronic acid in combination with G-CSF for use in mobilising blood stem cells |
| ES2370986B1 (es) * | 2010-06-08 | 2012-11-16 | Institut Quimic De Sarria Cets | Nuevos inhibidores de cxcr4 como agentes anti-vih |
| WO2012047339A2 (en) | 2010-06-28 | 2012-04-12 | The General Hospital Corporation | Anti-cxcr4 as a sensitizer to cancer therapeutics |
| CA2807552A1 (en) | 2010-08-06 | 2012-02-09 | Moderna Therapeutics, Inc. | Engineered nucleic acids and methods of use thereof |
| SI3590949T1 (sl) | 2010-10-01 | 2022-09-30 | Modernatx, Inc. | Ribonukleinske kisline, ki vsebujejo N1-metil-psevdouracil, in njihove uporabe |
| WO2012129073A2 (en) | 2011-03-18 | 2012-09-27 | University Of Virginia Patent Foundation | Compositions and methods for tissue engineering and cell based therapies |
| JP2014511687A (ja) | 2011-03-31 | 2014-05-19 | モデルナ セラピューティクス インコーポレイテッド | 工学操作された核酸の送達および製剤 |
| PL2709991T3 (pl) | 2011-05-16 | 2021-04-06 | Genzyme Corporation | Zastosowanie antagonistów CXCR4 w leczeniu zespołu WHIM, mielokateksji, neutropenii i limfocytopenii |
| WO2012174522A1 (en) * | 2011-06-16 | 2012-12-20 | Children's Medical Center Corporation | Combined chemical modification of sphingosine-1-phosphate (s1p) and cxcr4 signalling pathways for hematopoietic stem cell (hsc) mobilization and engraftment |
| US9464124B2 (en) | 2011-09-12 | 2016-10-11 | Moderna Therapeutics, Inc. | Engineered nucleic acids and methods of use thereof |
| EP2763701B1 (en) | 2011-10-03 | 2018-12-19 | Moderna Therapeutics, Inc. | Modified nucleosides, nucleotides, and nucleic acids, and uses thereof |
| RU2649364C2 (ru) | 2011-12-16 | 2018-04-02 | Модерна Терапьютикс, Инк. | Составы на основе модифицированного нуклеозида, нуклеотида и нуклеиновой кислоты |
| US9572897B2 (en) | 2012-04-02 | 2017-02-21 | Modernatx, Inc. | Modified polynucleotides for the production of cytoplasmic and cytoskeletal proteins |
| EP3520821A1 (en) | 2012-04-02 | 2019-08-07 | Moderna Therapeutics, Inc. | Modified polynucleotides for the production of biologics and proteins associated with human disease |
| US9283287B2 (en) | 2012-04-02 | 2016-03-15 | Moderna Therapeutics, Inc. | Modified polynucleotides for the production of nuclear proteins |
| US9878056B2 (en) | 2012-04-02 | 2018-01-30 | Modernatx, Inc. | Modified polynucleotides for the production of cosmetic proteins and peptides |
| SI2922554T1 (sl) | 2012-11-26 | 2022-06-30 | Modernatx, Inc. | Terminalno modificirana RNA |
| US8980864B2 (en) | 2013-03-15 | 2015-03-17 | Moderna Therapeutics, Inc. | Compositions and methods of altering cholesterol levels |
| US10023626B2 (en) | 2013-09-30 | 2018-07-17 | Modernatx, Inc. | Polynucleotides encoding immune modulating polypeptides |
| KR20160067219A (ko) | 2013-10-03 | 2016-06-13 | 모더나 세라퓨틱스, 인코포레이티드 | 저밀도 지단백질 수용체를 암호화하는 폴리뉴클레오타이드 |
| WO2016191811A1 (en) * | 2015-06-03 | 2016-12-08 | The University Of Queensland | Mobilizing agents and uses therefor |
| EP3389720A1 (en) | 2015-12-18 | 2018-10-24 | The General Hospital Corporation | Polyacetal polymers, conjugates, particles and uses thereof |
| EP4360567A3 (en) * | 2016-10-24 | 2024-07-31 | Yale University | Aspiration device |
| WO2018106738A1 (en) | 2016-12-05 | 2018-06-14 | Massachusetts Institute Of Technology | Brush-arm star polymers, conjugates and particles, and uses thereof |
| SG11202003795YA (en) | 2017-11-03 | 2020-05-28 | Roemer & Heigl Gmbh | Extraction of stem cells from bone marrow niches |
| US10058573B1 (en) | 2017-12-06 | 2018-08-28 | Magenta Therapeutics, Inc. | Dosing regimens for the mobilization of hematopoietic stem cells |
| US11260079B2 (en) | 2017-12-06 | 2022-03-01 | Magenta Therapeutics, Inc. | Dosing regimens for the mobilization of hematopoietic stem and progenitor cells |
| EP4146797A1 (en) | 2020-05-06 | 2023-03-15 | Orchard Therapeutics (Europe) Limited | Treatment for neurodegenerative diseases |
| WO2022101359A1 (en) | 2020-11-12 | 2022-05-19 | Roemer & Heigl Gmbh | Reversible release of stem cells from bone marrow niches |
| WO2025224720A1 (en) | 2024-04-24 | 2025-10-30 | Biolinerx Ltd. | Methods of selecting treatment regimen against solid tumors |
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| US4810643A (en) * | 1985-08-23 | 1989-03-07 | Kirin- Amgen Inc. | Production of pluripotent granulocyte colony-stimulating factor |
| US5194596A (en) * | 1989-07-27 | 1993-03-16 | California Biotechnology Inc. | Production of vascular endothelial cell growth factor |
| US5350836A (en) * | 1989-10-12 | 1994-09-27 | Ohio University | Growth hormone antagonists |
| US6001826A (en) * | 1989-12-21 | 1999-12-14 | Anormed, Inc. | Chemical compounds |
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- 2007-08-07 AU AU2007281677A patent/AU2007281677A1/en not_active Abandoned
- 2007-08-07 MX MX2009001445A patent/MX2009001445A/es unknown
- 2007-08-07 US US12/376,591 patent/US20100178271A1/en not_active Abandoned
- 2007-08-07 RU RU2009108289/15A patent/RU2009108289A/ru not_active Application Discontinuation
- 2007-08-07 EP EP07813853A patent/EP2056853A1/en active Pending
- 2007-08-07 WO PCT/US2007/075376 patent/WO2008019371A1/en not_active Ceased
- 2007-08-07 CA CA002659337A patent/CA2659337A1/en not_active Abandoned
- 2007-08-07 JP JP2009523960A patent/JP2010507567A/ja not_active Withdrawn
- 2007-08-07 BR BRPI0715393-7A patent/BRPI0715393A2/pt not_active Application Discontinuation
- 2007-08-07 CN CNA2007800295078A patent/CN101500595A/zh active Pending
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2009
- 2009-01-15 IL IL196559A patent/IL196559A0/en unknown
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105431521A (zh) * | 2013-02-28 | 2016-03-23 | 哈佛学院校长同事会 | 用于动员干细胞的方法和组合物 |
| CN113616779A (zh) * | 2013-02-28 | 2021-11-09 | 哈佛学院校长同事会 | 用于动员干细胞的方法和组合物 |
| CN111712262A (zh) * | 2017-12-06 | 2020-09-25 | 美真达治疗公司 | 用于动员造血干细胞和祖细胞的给药方案 |
Also Published As
| Publication number | Publication date |
|---|---|
| AU2007281677A1 (en) | 2008-02-14 |
| AR062271A1 (es) | 2008-10-29 |
| BRPI0715393A2 (pt) | 2013-06-25 |
| US20100178271A1 (en) | 2010-07-15 |
| JP2010507567A (ja) | 2010-03-11 |
| EP2056853A1 (en) | 2009-05-13 |
| CA2659337A1 (en) | 2008-02-14 |
| MX2009001445A (es) | 2009-02-18 |
| RU2009108289A (ru) | 2010-09-20 |
| WO2008019371A1 (en) | 2008-02-14 |
| IL196559A0 (en) | 2011-08-01 |
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