CN101489613A - 用于对干粉状药物进行给药的吸入系统和递送装置 - Google Patents
用于对干粉状药物进行给药的吸入系统和递送装置 Download PDFInfo
- Publication number
- CN101489613A CN101489613A CNA2007800266785A CN200780026678A CN101489613A CN 101489613 A CN101489613 A CN 101489613A CN A2007800266785 A CNA2007800266785 A CN A2007800266785A CN 200780026678 A CN200780026678 A CN 200780026678A CN 101489613 A CN101489613 A CN 101489613A
- Authority
- CN
- China
- Prior art keywords
- drug cavity
- drug
- elastic component
- intake system
- delivery apparatus
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M11/00—Sprayers or atomisers specially adapted for therapeutic purposes
- A61M11/001—Particle size control
- A61M11/002—Particle size control by flow deviation causing inertial separation of transported particles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0001—Details of inhalators; Constructional features thereof
- A61M15/0003—Details of inhalators; Constructional features thereof with means for dispensing more than one drug
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
- A61M15/003—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using capsules, e.g. to be perforated or broken-up
- A61M15/0043—Non-destructive separation of the package, e.g. peeling
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0091—Inhalators mechanically breath-triggered
- A61M15/0096—Hindering inhalation before activation of the dispenser
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0086—Inhalation chambers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2202/00—Special media to be introduced, removed or treated
- A61M2202/06—Solids
- A61M2202/064—Powder
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/07—General characteristics of the apparatus having air pumping means
- A61M2205/071—General characteristics of the apparatus having air pumping means hand operated
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/60—General characteristics of the apparatus with identification means
- A61M2205/6045—General characteristics of the apparatus with identification means having complementary physical shapes for indexing or registration purposes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2206/00—Characteristics of a physical parameter; associated device therefor
- A61M2206/10—Flow characteristics
- A61M2206/14—Static flow deviators in tubes disturbing laminar flow in tubes, e.g. archimedes screws
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pulmonology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US83114506P | 2006-07-14 | 2006-07-14 | |
| US60/831,145 | 2006-07-14 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN101489613A true CN101489613A (zh) | 2009-07-22 |
Family
ID=38923494
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNA2007800266785A Pending CN101489613A (zh) | 2006-07-14 | 2007-07-12 | 用于对干粉状药物进行给药的吸入系统和递送装置 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US20090250058A1 (enExample) |
| EP (1) | EP2043717A1 (enExample) |
| JP (1) | JP2009543658A (enExample) |
| CN (1) | CN101489613A (enExample) |
| WO (1) | WO2008008021A1 (enExample) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104114213A (zh) * | 2011-12-16 | 2014-10-22 | 赛诺菲股份有限公司 | 通过吸入向病人施用粉末状药物的装置 |
| CN107921225A (zh) * | 2015-06-03 | 2018-04-17 | 艾克诺韦公司 | 单剂量干粉吸入器 |
| CN108057154A (zh) * | 2012-07-12 | 2018-05-22 | 曼金德公司 | 干粉药物输送系统和方法 |
| WO2025167439A1 (zh) * | 2024-02-07 | 2025-08-14 | 长风药业股份有限公司 | 药粉测量杆、药粉测量杆组件及药粉测量系统 |
Families Citing this family (46)
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| US9006175B2 (en) | 1999-06-29 | 2015-04-14 | Mannkind Corporation | Potentiation of glucose elimination |
| SI1494732T1 (sl) | 2002-03-20 | 2008-08-31 | Mannking Corp | Inhalacijski aparat |
| KR101273120B1 (ko) | 2004-08-20 | 2013-06-13 | 맨카인드 코포레이션 | 다이케토피페라진 합성의 촉매 작용 |
| BR122019022692B1 (pt) | 2004-08-23 | 2023-01-10 | Mannkind Corporation | Composição terapêutica em pó seco contendo dicetopiperazina, pelo menos um tipo de cátion e um agente biologicamente ativo |
| KR101486829B1 (ko) | 2005-09-14 | 2015-01-29 | 맨카인드 코포레이션 | 결정질 미립자 표면에 대한 활성제의 친화력의 증가를 기반으로 하는 약물 제제의 방법 |
| EP1986679B1 (en) | 2006-02-22 | 2017-10-25 | MannKind Corporation | A method for improving the pharmaceutic properties of microparticles comprising diketopiperazine and an active agent |
| JP5570996B2 (ja) | 2007-12-14 | 2014-08-13 | エアロデザインズ インコーポレイテッド | エアロゾル化可能な食料品の送達 |
| MX2010006657A (es) | 2007-12-20 | 2010-10-05 | Astrazeneca Ab | Dispositivo y metodo para desagregar polvo 854. |
| AU2014200952B2 (en) * | 2008-06-13 | 2014-12-11 | Mannkind Corporation | A dry powder inhaler and system for drug delivery |
| TWI677355B (zh) * | 2008-06-13 | 2019-11-21 | 美商曼凱公司 | 用於藥物傳輸之乾粉吸入器及系統 |
| US8485180B2 (en) | 2008-06-13 | 2013-07-16 | Mannkind Corporation | Dry powder drug delivery system |
| AU2015275293B2 (en) * | 2008-06-13 | 2018-06-07 | Mannkind Corporation | A dry powder inhaler and system for drug delivery |
| ES2421385T3 (es) | 2008-06-20 | 2013-09-02 | Mannkind Corp | Aparato interactivo y procedimiento para establecer el perfil, en tiempo real, de esfuerzos de inhalación |
| TWI614024B (zh) | 2008-08-11 | 2018-02-11 | 曼凱公司 | 超快起作用胰島素之用途 |
| US8302602B2 (en) | 2008-09-30 | 2012-11-06 | Nellcor Puritan Bennett Llc | Breathing assistance system with multiple pressure sensors |
| US8314106B2 (en) | 2008-12-29 | 2012-11-20 | Mannkind Corporation | Substituted diketopiperazine analogs for use as drug delivery agents |
| EP2676695A3 (en) | 2009-03-11 | 2017-03-01 | MannKind Corporation | Apparatus, system and method for measuring resistance of an inhaler |
| MY186975A (en) | 2009-06-12 | 2021-08-26 | Mannkind Corp | Diketopiperazine microparticles with defined specific surface areas |
| AU2010266754B2 (en) | 2009-07-01 | 2013-12-05 | Astrazeneca Ab | Dispenser and method for entraining powder in an airflow |
| US9016147B2 (en) | 2009-11-03 | 2015-04-28 | Mannkind Corporation | Apparatus and method for simulating inhalation efforts |
| CA2779488A1 (en) | 2009-11-12 | 2011-05-19 | Stc.Unm | Dry powder inhaler with flutter dispersion member |
| MX359281B (es) | 2010-06-21 | 2018-09-21 | Mannkind Corp | Sistema y metodos para suministrar un farmaco en polvo seco. |
| WO2012078804A1 (en) | 2010-12-07 | 2012-06-14 | Respira Therapeutics, Inc. | Dry powder inhaler |
| US8925726B2 (en) | 2011-04-01 | 2015-01-06 | Mannkind Corporation | Blister package for pharmaceutical cartridges |
| WO2012174472A1 (en) | 2011-06-17 | 2012-12-20 | Mannkind Corporation | High capacity diketopiperazine microparticles |
| CN106730186B (zh) * | 2011-09-07 | 2020-06-09 | 康森特里克斯药物公司 | 干粉吸入装置 |
| CA2852536A1 (en) | 2011-10-24 | 2013-05-02 | Mannkind Corporation | Methods and compositions for treating pain |
| US10463815B2 (en) | 2012-02-21 | 2019-11-05 | Respira Therapeutics, Inc. | Inhaler to deliver substances for prophylaxis or prevention of disease or injury caused by the inhalation of biological or chemical agents |
| US8844526B2 (en) | 2012-03-30 | 2014-09-30 | Covidien Lp | Methods and systems for triggering with unknown base flow |
| EP2911690A1 (en) | 2012-10-26 | 2015-09-02 | MannKind Corporation | Inhalable influenza vaccine compositions and methods |
| US9492629B2 (en) | 2013-02-14 | 2016-11-15 | Covidien Lp | Methods and systems for ventilation with unknown exhalation flow and exhalation pressure |
| US9981096B2 (en) | 2013-03-13 | 2018-05-29 | Covidien Lp | Methods and systems for triggering with unknown inspiratory flow |
| EP2970149B1 (en) | 2013-03-15 | 2019-08-21 | MannKind Corporation | Microcrystalline diketopiperazine compositions and methods |
| SE1300485A1 (sv) * | 2013-04-23 | 2014-10-24 | Simplified Solutions Sweden Ab | Engångs-inhalator för ämnen i pulverform |
| EP3021834A1 (en) | 2013-07-18 | 2016-05-25 | MannKind Corporation | Heat-stable dry powder pharmaceutical compositions and methods |
| CN105517607A (zh) | 2013-08-05 | 2016-04-20 | 曼金德公司 | 吹入设备和方法 |
| US10307464B2 (en) | 2014-03-28 | 2019-06-04 | Mannkind Corporation | Use of ultrarapid acting insulin |
| EP3137140B1 (en) * | 2014-05-02 | 2019-07-10 | Manta Devices, LLC | Delivery device |
| US10561806B2 (en) | 2014-10-02 | 2020-02-18 | Mannkind Corporation | Mouthpiece cover for an inhaler |
| CA2972826C (en) | 2015-01-14 | 2023-09-12 | Respira Therapeutics, Inc. | Powder dispersion methods and devices |
| US9925346B2 (en) | 2015-01-20 | 2018-03-27 | Covidien Lp | Systems and methods for ventilation with unknown exhalation flow |
| PT108426B (pt) | 2015-04-30 | 2017-07-24 | Hovione Farmaciência S A | Inalador de pó para administração de doses elevadas de fármacos |
| EP3600504B1 (en) | 2017-03-28 | 2023-07-12 | Concentrx Pharmaceuticals, Inc. | Device for delivering dry powder medicaments |
| EA201992119A1 (ru) * | 2017-04-06 | 2020-03-27 | Милан Инк. | Недорогой ингалятор порошка для одноразового использования |
| GB201713899D0 (en) * | 2017-08-30 | 2017-10-11 | Indosys Ltd | Multi-dose medicament delivery device |
| US11607509B2 (en) * | 2017-09-19 | 2023-03-21 | Iconovo Ab | Dry powder inhaler comprising a casing with a first casing portion and a second casing portion |
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| JP2005527260A (ja) * | 2002-01-25 | 2005-09-15 | グラクソ グループ リミテッド | 薬剤ディスペンサ |
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| US20040177848A1 (en) * | 2003-03-12 | 2004-09-16 | Alley Kenneth A. | Multi-compartment inhaler |
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| JP4708369B2 (ja) * | 2004-02-24 | 2011-06-22 | マイクロドース セラピューテクス,インコーポレイテッド | 合成ジェットに基づく薬剤投与装置 |
-
2007
- 2007-07-12 EP EP07768996A patent/EP2043717A1/en not_active Withdrawn
- 2007-07-12 WO PCT/SE2007/000682 patent/WO2008008021A1/en not_active Ceased
- 2007-07-12 CN CNA2007800266785A patent/CN101489613A/zh active Pending
- 2007-07-12 US US12/373,720 patent/US20090250058A1/en not_active Abandoned
- 2007-07-12 JP JP2009520707A patent/JP2009543658A/ja active Pending
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104114213A (zh) * | 2011-12-16 | 2014-10-22 | 赛诺菲股份有限公司 | 通过吸入向病人施用粉末状药物的装置 |
| CN104114213B (zh) * | 2011-12-16 | 2016-06-22 | 赛诺菲股份有限公司 | 通过吸入向病人施用粉末状药物的装置 |
| CN108057154A (zh) * | 2012-07-12 | 2018-05-22 | 曼金德公司 | 干粉药物输送系统和方法 |
| CN108057154B (zh) * | 2012-07-12 | 2021-04-16 | 曼金德公司 | 干粉药物输送系统和方法 |
| CN107921225A (zh) * | 2015-06-03 | 2018-04-17 | 艾克诺韦公司 | 单剂量干粉吸入器 |
| WO2025167439A1 (zh) * | 2024-02-07 | 2025-08-14 | 长风药业股份有限公司 | 药粉测量杆、药粉测量杆组件及药粉测量系统 |
Also Published As
| Publication number | Publication date |
|---|---|
| JP2009543658A (ja) | 2009-12-10 |
| WO2008008021A1 (en) | 2008-01-17 |
| US20090250058A1 (en) | 2009-10-08 |
| EP2043717A1 (en) | 2009-04-08 |
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