CN101489613A - 用于对干粉状药物进行给药的吸入系统和递送装置 - Google Patents
用于对干粉状药物进行给药的吸入系统和递送装置 Download PDFInfo
- Publication number
- CN101489613A CN101489613A CNA2007800266785A CN200780026678A CN101489613A CN 101489613 A CN101489613 A CN 101489613A CN A2007800266785 A CNA2007800266785 A CN A2007800266785A CN 200780026678 A CN200780026678 A CN 200780026678A CN 101489613 A CN101489613 A CN 101489613A
- Authority
- CN
- China
- Prior art keywords
- drug cavity
- drug
- elastic component
- intake system
- delivery apparatus
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M11/00—Sprayers or atomisers specially adapted for therapeutic purposes
- A61M11/001—Particle size control
- A61M11/002—Particle size control by flow deviation causing inertial separation of transported particles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0001—Details of inhalators; Constructional features thereof
- A61M15/0003—Details of inhalators; Constructional features thereof with means for dispensing more than one drug
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
- A61M15/003—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using capsules, e.g. to be perforated or broken-up
- A61M15/0043—Non-destructive separation of the package, e.g. peeling
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0091—Inhalators mechanically breath-triggered
- A61M15/0096—Hindering inhalation before activation of the dispenser
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0086—Inhalation chambers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2202/00—Special media to be introduced, removed or treated
- A61M2202/06—Solids
- A61M2202/064—Powder
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/07—General characteristics of the apparatus having air pumping means
- A61M2205/071—General characteristics of the apparatus having air pumping means hand operated
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/60—General characteristics of the apparatus with identification means
- A61M2205/6045—General characteristics of the apparatus with identification means having complementary physical shapes for indexing or registration purposes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2206/00—Characteristics of a physical parameter; associated device therefor
- A61M2206/10—Flow characteristics
- A61M2206/14—Static flow deviators in tubes disturbing laminar flow in tubes, e.g. archimedes screws
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pulmonology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US83114506P | 2006-07-14 | 2006-07-14 | |
| US60/831,145 | 2006-07-14 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN101489613A true CN101489613A (zh) | 2009-07-22 |
Family
ID=38923494
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNA2007800266785A Pending CN101489613A (zh) | 2006-07-14 | 2007-07-12 | 用于对干粉状药物进行给药的吸入系统和递送装置 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US20090250058A1 (enExample) |
| EP (1) | EP2043717A1 (enExample) |
| JP (1) | JP2009543658A (enExample) |
| CN (1) | CN101489613A (enExample) |
| WO (1) | WO2008008021A1 (enExample) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104114213A (zh) * | 2011-12-16 | 2014-10-22 | 赛诺菲股份有限公司 | 通过吸入向病人施用粉末状药物的装置 |
| CN107921225A (zh) * | 2015-06-03 | 2018-04-17 | 艾克诺韦公司 | 单剂量干粉吸入器 |
| CN108057154A (zh) * | 2012-07-12 | 2018-05-22 | 曼金德公司 | 干粉药物输送系统和方法 |
| WO2025167439A1 (zh) * | 2024-02-07 | 2025-08-14 | 长风药业股份有限公司 | 药粉测量杆、药粉测量杆组件及药粉测量系统 |
Families Citing this family (46)
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| US9006175B2 (en) | 1999-06-29 | 2015-04-14 | Mannkind Corporation | Potentiation of glucose elimination |
| AU2003220125B2 (en) | 2002-03-20 | 2006-06-15 | Mannkind Corporation | Inhalation apparatus |
| PL1786784T3 (pl) | 2004-08-20 | 2011-04-29 | Mannkind Corp | Kataliza syntezy diketopiperazyn |
| EP2314298B1 (en) | 2004-08-23 | 2015-05-27 | MannKind Corporation | Microparticles comprising diketopiperazine salts for drug delivery |
| AU2006290870B2 (en) | 2005-09-14 | 2013-02-28 | Mannkind Corporation | Method of drug formulation based on increasing the affinity of active agents for crystalline microparticle surfaces |
| DK1986679T3 (da) | 2006-02-22 | 2017-11-20 | Mannkind Corp | Fremgangsmåde til forbedring af mikropartiklers farmaceutiske egenskaber omfattende diketopiperazin og et aktivt indholdsstof |
| WO2009079078A1 (en) | 2007-12-14 | 2009-06-25 | Labogroup S.A.S. | Delivering aerosolizable food products |
| MX2010006657A (es) | 2007-12-20 | 2010-10-05 | Astrazeneca Ab | Dispositivo y metodo para desagregar polvo 854. |
| AU2015275293B2 (en) * | 2008-06-13 | 2018-06-07 | Mannkind Corporation | A dry powder inhaler and system for drug delivery |
| CN103252007B (zh) | 2008-06-13 | 2016-06-22 | 曼金德公司 | 干粉吸入器和用于药物输送的系统 |
| US8485180B2 (en) | 2008-06-13 | 2013-07-16 | Mannkind Corporation | Dry powder drug delivery system |
| AU2014200952B2 (en) * | 2008-06-13 | 2014-12-11 | Mannkind Corporation | A dry powder inhaler and system for drug delivery |
| JP5479465B2 (ja) | 2008-06-20 | 2014-04-23 | マンカインド コーポレイション | 吸入努力をリアルタイムにプロファイルする対話式機器および方法 |
| TWI614024B (zh) | 2008-08-11 | 2018-02-11 | 曼凱公司 | 超快起作用胰島素之用途 |
| US8302602B2 (en) | 2008-09-30 | 2012-11-06 | Nellcor Puritan Bennett Llc | Breathing assistance system with multiple pressure sensors |
| US8314106B2 (en) | 2008-12-29 | 2012-11-20 | Mannkind Corporation | Substituted diketopiperazine analogs for use as drug delivery agents |
| EP2676695A3 (en) | 2009-03-11 | 2017-03-01 | MannKind Corporation | Apparatus, system and method for measuring resistance of an inhaler |
| KR101875969B1 (ko) | 2009-06-12 | 2018-07-06 | 맨카인드 코포레이션 | 한정된 비표면적을 갖는 디케토피페라진 마이크로입자 |
| JP2012531961A (ja) * | 2009-07-01 | 2012-12-13 | アストラゼネカ・アクチエボラーグ | 粉末を気流に引き込むためのディスペンサーおよび方法 |
| WO2011056889A1 (en) | 2009-11-03 | 2011-05-12 | Mannkind Corporation | An apparatus and method for simulating inhalation efforts |
| CA2779488A1 (en) | 2009-11-12 | 2011-05-19 | Stc.Unm | Dry powder inhaler with flutter dispersion member |
| RU2531455C2 (ru) | 2010-06-21 | 2014-10-20 | Маннкайнд Корпорейшн | Системы и способы доставки сухих порошковых лекарств |
| JP6050758B2 (ja) | 2010-12-07 | 2016-12-21 | レスピラ セラピューティクス インコーポレイテッドRespira Therapeutics,Inc. | 乾燥粉末吸入器及びその作動方法 |
| CN105667994B (zh) | 2011-04-01 | 2018-04-06 | 曼金德公司 | 用于药物药盒的泡罩包装 |
| WO2012174472A1 (en) | 2011-06-17 | 2012-12-20 | Mannkind Corporation | High capacity diketopiperazine microparticles |
| WO2013036881A2 (en) * | 2011-09-07 | 2013-03-14 | Syphase, Llc | Dry powder inhalation device |
| WO2013063160A1 (en) | 2011-10-24 | 2013-05-02 | Mannkind Corporation | Methods and compositions for treating pain |
| US10463815B2 (en) | 2012-02-21 | 2019-11-05 | Respira Therapeutics, Inc. | Inhaler to deliver substances for prophylaxis or prevention of disease or injury caused by the inhalation of biological or chemical agents |
| US8844526B2 (en) | 2012-03-30 | 2014-09-30 | Covidien Lp | Methods and systems for triggering with unknown base flow |
| EP2911690A1 (en) | 2012-10-26 | 2015-09-02 | MannKind Corporation | Inhalable influenza vaccine compositions and methods |
| US9492629B2 (en) | 2013-02-14 | 2016-11-15 | Covidien Lp | Methods and systems for ventilation with unknown exhalation flow and exhalation pressure |
| US9981096B2 (en) | 2013-03-13 | 2018-05-29 | Covidien Lp | Methods and systems for triggering with unknown inspiratory flow |
| EP2970149B1 (en) | 2013-03-15 | 2019-08-21 | MannKind Corporation | Microcrystalline diketopiperazine compositions and methods |
| SE1300485A1 (sv) * | 2013-04-23 | 2014-10-24 | Simplified Solutions Sweden Ab | Engångs-inhalator för ämnen i pulverform |
| CN105451716A (zh) | 2013-07-18 | 2016-03-30 | 曼金德公司 | 热稳定性干粉药物组合物和方法 |
| WO2015021064A1 (en) | 2013-08-05 | 2015-02-12 | Mannkind Corporation | Insufflation apparatus and methods |
| US10307464B2 (en) | 2014-03-28 | 2019-06-04 | Mannkind Corporation | Use of ultrarapid acting insulin |
| WO2015168572A2 (en) * | 2014-05-02 | 2015-11-05 | Manta Devices, Llc | Delivery device and related methods |
| US10561806B2 (en) | 2014-10-02 | 2020-02-18 | Mannkind Corporation | Mouthpiece cover for an inhaler |
| EP3244952A4 (en) | 2015-01-14 | 2018-11-14 | Respira Therapeutics, Inc. | Powder dispersion methods and devices |
| US9925346B2 (en) | 2015-01-20 | 2018-03-27 | Covidien Lp | Systems and methods for ventilation with unknown exhalation flow |
| PT108426B (pt) | 2015-04-30 | 2017-07-24 | Hovione Farmaciência S A | Inalador de pó para administração de doses elevadas de fármacos |
| CA3057683A1 (en) | 2017-03-28 | 2018-10-04 | Concentrx Pharmaceuticals, Inc. | Devices and methods for delivering dry powder medicaments |
| EA201992119A1 (ru) * | 2017-04-06 | 2020-03-27 | Милан Инк. | Недорогой ингалятор порошка для одноразового использования |
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| EP3684449B1 (en) * | 2017-09-19 | 2023-06-21 | Iconovo AB | A dry-powder inhaler comprising a casing with a first casing portion and a second casing portion |
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-
2007
- 2007-07-12 US US12/373,720 patent/US20090250058A1/en not_active Abandoned
- 2007-07-12 CN CNA2007800266785A patent/CN101489613A/zh active Pending
- 2007-07-12 EP EP07768996A patent/EP2043717A1/en not_active Withdrawn
- 2007-07-12 JP JP2009520707A patent/JP2009543658A/ja active Pending
- 2007-07-12 WO PCT/SE2007/000682 patent/WO2008008021A1/en not_active Ceased
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104114213A (zh) * | 2011-12-16 | 2014-10-22 | 赛诺菲股份有限公司 | 通过吸入向病人施用粉末状药物的装置 |
| CN104114213B (zh) * | 2011-12-16 | 2016-06-22 | 赛诺菲股份有限公司 | 通过吸入向病人施用粉末状药物的装置 |
| CN108057154A (zh) * | 2012-07-12 | 2018-05-22 | 曼金德公司 | 干粉药物输送系统和方法 |
| CN108057154B (zh) * | 2012-07-12 | 2021-04-16 | 曼金德公司 | 干粉药物输送系统和方法 |
| CN107921225A (zh) * | 2015-06-03 | 2018-04-17 | 艾克诺韦公司 | 单剂量干粉吸入器 |
| WO2025167439A1 (zh) * | 2024-02-07 | 2025-08-14 | 长风药业股份有限公司 | 药粉测量杆、药粉测量杆组件及药粉测量系统 |
Also Published As
| Publication number | Publication date |
|---|---|
| US20090250058A1 (en) | 2009-10-08 |
| EP2043717A1 (en) | 2009-04-08 |
| JP2009543658A (ja) | 2009-12-10 |
| WO2008008021A1 (en) | 2008-01-17 |
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