CN101472607A - 禽流感血凝素的新型dna序列、载体和蛋白质 - Google Patents

禽流感血凝素的新型dna序列、载体和蛋白质 Download PDF

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Publication number
CN101472607A
CN101472607A CNA2007800223807A CN200780022380A CN101472607A CN 101472607 A CN101472607 A CN 101472607A CN A2007800223807 A CNA2007800223807 A CN A2007800223807A CN 200780022380 A CN200780022380 A CN 200780022380A CN 101472607 A CN101472607 A CN 101472607A
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polypeptide
aminoacid
seq
fragment
sequence
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Chinese (zh)
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M·亨利
I·M·拉里努亚
S·M·拉塞尔
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Corteva Agriscience LLC
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Dow AgroSciences LLC
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    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C07K14/08RNA viruses
    • C07K14/11Orthomyxoviridae, e.g. influenza virus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • A61K39/145Orthomyxoviridae, e.g. influenza virus
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
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    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8242Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
    • C12N15/8257Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits for the production of primary gene products, e.g. pharmaceutical products, interferon
    • C12N15/8258Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits for the production of primary gene products, e.g. pharmaceutical products, interferon for the production of oral vaccines (antigens) or immunoglobulins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/517Plant cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/545Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011Details
    • C12N2760/16011Orthomyxoviridae
    • C12N2760/16111Influenzavirus A, i.e. influenza A virus
    • C12N2760/16122New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011Details
    • C12N2760/16011Orthomyxoviridae
    • C12N2760/16111Influenzavirus A, i.e. influenza A virus
    • C12N2760/16134Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Virology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Immunology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • General Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Communicable Diseases (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
CNA2007800223807A 2006-06-16 2007-06-08 禽流感血凝素的新型dna序列、载体和蛋白质 Pending CN101472607A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US81424106P 2006-06-16 2006-06-16
US60/814,241 2006-06-16

Publications (1)

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CN101472607A true CN101472607A (zh) 2009-07-01

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CNA2007800223807A Pending CN101472607A (zh) 2006-06-16 2007-06-08 禽流感血凝素的新型dna序列、载体和蛋白质

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Country Link
US (1) US8163876B2 (enExample)
EP (1) EP2029167A4 (enExample)
JP (1) JP2009540801A (enExample)
KR (1) KR20090027216A (enExample)
CN (1) CN101472607A (enExample)
AR (1) AR061484A1 (enExample)
AU (1) AU2007261196A1 (enExample)
BR (1) BRPI0713671A2 (enExample)
CA (1) CA2654178A1 (enExample)
WO (1) WO2007149715A2 (enExample)
ZA (1) ZA200808845B (enExample)

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Publication number Priority date Publication date Assignee Title
CN1833030B (zh) 2003-05-22 2014-07-23 美国弗劳恩霍夫股份有限公司 用于表达、传递及纯化目标多肽的重组载体分子
BRPI0614475B8 (pt) 2005-08-03 2021-05-25 Fraunhofer Usa Inc polipeptídeo, anticorpo, ácido nucleico, vetores, célula hospedeira, composição e processos de produção de anticorpo
EP2029167A4 (en) * 2006-06-16 2010-06-16 Dow Agrosciences Llc NEW DNA SEQUENCES, VECTORS AND PROTEINS OF BIRD FLUID HEMOGGLUTININE
EP2092059A4 (en) 2006-10-24 2012-03-28 Bogoch Samuel METHOD FOR FORECASTING INFLUENZA EXCESSIONS BY CORRELATION OF AN INCREASED REPLICINE MIRROR IN WHITE SPOT AND / OR TAURA VIRUSES IN CRABES
JP5675348B2 (ja) 2007-05-30 2015-02-25 ボゴーク,サミュエル 水産養殖における無脊椎動物の病原性感染に対する合成レプリキンペプチド
CA2692933C (en) 2007-07-11 2016-10-18 Fraunhofer Usa, Inc. Yersinia pestis antigens, vaccine compositions, and related methods
EP2300493A2 (en) * 2008-04-23 2011-03-30 Samuel Bogoch Methods and compounds for mitigating pathogenic outbreaks using replikin count cycles
ES2593277T3 (es) * 2008-07-18 2016-12-07 Medicago Inc. Nuevo epítopo de inmunización contra el virus de la influenza
WO2010036970A2 (en) * 2008-09-25 2010-04-01 Fraunhofer Usa, Inc. Influenza vaccines, antigens, compositions, and methods
US8734803B2 (en) 2008-09-28 2014-05-27 Ibio Inc. Humanized neuraminidase antibody and methods of use thereof
US9233148B2 (en) 2009-01-09 2016-01-12 Samuel Bogoch Replikin-based compounds for prevention and treatment of influenza and methods of differentiating infectivity and lethality in influenza
CA2759325A1 (en) * 2009-04-23 2010-10-28 Samuel Bogoch Replikin-sequences for preventing/treating influenza and determining infectivity/lethality
WO2011041391A1 (en) 2009-09-29 2011-04-07 Fraunhofer Usa, Inc. Influenza hemagglutinin antibodies, compositions, and related methods
CN101693894B (zh) * 2009-10-15 2011-07-27 北京大学深圳研究生院 禽流感病毒h5n1假病毒及其制备方法与专用dna片段
AR083533A1 (es) * 2010-10-22 2013-03-06 Boehringer Ingelheim Vetmed Proteinas de hemaglutinina 5 (h5) para el tratamiento y prevencion de las infecciones de gripe
WO2013013075A2 (en) 2011-07-20 2013-01-24 Samuel Bogoch Peptides shared among lethal cancers and therapeutic compositions comprising said peptides
CN116218900A (zh) * 2011-09-30 2023-06-06 麦迪卡格公司 增加植物中病毒样颗粒的产率
US9969794B2 (en) 2012-05-10 2018-05-15 Visterra, Inc. HA binding agents
RU2531235C2 (ru) 2013-02-15 2014-10-20 Общество с ограниченной ответственностью "Универсальные БиоСистемы" (ООО "УБС") Поливалентная вакцина против гриппа на основе гибридного белка
WO2015048129A1 (en) * 2013-09-24 2015-04-02 CHOI, Duk, Kyung Avian influenza virus polypeptides and methods of their use
US10513553B2 (en) 2015-11-13 2019-12-24 Visterra, Inc. Compositions and methods for treating and preventing influenza
CA3015347A1 (en) 2016-02-24 2017-08-31 Visterra, Inc. Formulations of antibody molecules to influenza virus
GB2578163A (en) * 2018-10-19 2020-04-22 Univ Pretoria Plant produced avian influenza antigens and their uses in diagnostic assays and devices
JP2022521819A (ja) 2019-03-25 2022-04-12 ビステラ, インコーポレイテッド インフルエンザを処置および予防するための組成物および方法
US20240191245A1 (en) * 2021-03-18 2024-06-13 Calyxt, Inc. Plant cell matrices and methods thereof
WO2023032008A1 (ja) * 2021-08-30 2023-03-09 日環科学株式会社 免疫賦活化製剤と当該免疫賦活製剤を含有する化粧品、食品、飼料添加物、医薬部外品

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004098533A2 (en) 2003-05-05 2004-11-18 Boyce Thompson Institute For Plant Research Vectors and cells for preparing immunoprotective compositions derived from transgenic plants
AU2005248375B2 (en) * 2004-05-25 2010-12-16 Medimmune, Llc Influenza hemagglutinin and neuraminidase varians
JP2009535306A (ja) 2006-04-21 2009-10-01 ダウ・アグロサイエンス・エル・エル・シー 鳥インフルエンザに対するワクチンおよび使用方法
EP2029167A4 (en) * 2006-06-16 2010-06-16 Dow Agrosciences Llc NEW DNA SEQUENCES, VECTORS AND PROTEINS OF BIRD FLUID HEMOGGLUTININE

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Publication number Publication date
JP2009540801A (ja) 2009-11-26
KR20090027216A (ko) 2009-03-16
WO2007149715A3 (en) 2008-07-24
ZA200808845B (en) 2009-10-28
EP2029167A4 (en) 2010-06-16
BRPI0713671A2 (pt) 2013-12-03
AR061484A1 (es) 2008-08-27
WO2007149715A2 (en) 2007-12-27
EP2029167A2 (en) 2009-03-04
AU2007261196A1 (en) 2007-12-27
US8163876B2 (en) 2012-04-24
CA2654178A1 (en) 2007-12-27
US20090106864A1 (en) 2009-04-23

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