CN101467036B - 全血样品的差异溶血 - Google Patents

全血样品的差异溶血 Download PDF

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Publication number
CN101467036B
CN101467036B CN2007800212732A CN200780021273A CN101467036B CN 101467036 B CN101467036 B CN 101467036B CN 2007800212732 A CN2007800212732 A CN 2007800212732A CN 200780021273 A CN200780021273 A CN 200780021273A CN 101467036 B CN101467036 B CN 101467036B
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China
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sample
whole blood
analyte
red blood
lytic agent
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Chinese (zh)
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CN101467036A (zh
Inventor
U·科博尔德
T·多尔弗
R·赫曼
H·冯德埃尔茨
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F Hoffmann La Roche AG
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F Hoffmann La Roche AG
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/04—Preparation or injection of sample to be analysed
    • G01N30/06—Preparation
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5002—Partitioning blood components
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N2030/022—Column chromatography characterised by the kind of separation mechanism
    • G01N2030/027—Liquid chromatography
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/60—Construction of the column
    • G01N30/6004—Construction of the column end pieces
    • G01N30/603—Construction of the column end pieces retaining the stationary phase, e.g. Frits
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/62—Detectors specially adapted therefor
    • G01N30/72—Mass spectrometers
    • G01N30/7233—Mass spectrometers interfaced to liquid or supercritical fluid chromatograph
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/24—Nuclear magnetic resonance, electron spin resonance or other spin effects or mass spectrometry
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/25—Chemistry: analytical and immunological testing including sample preparation

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Hematology (AREA)
  • General Physics & Mathematics (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Sampling And Sample Adjustment (AREA)
CN2007800212732A 2006-06-06 2007-06-04 全血样品的差异溶血 Active CN101467036B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP06011604.3 2006-06-06
EP06011604 2006-06-06
PCT/EP2007/004923 WO2007140961A1 (en) 2006-06-06 2007-06-04 Differential hemolysis of a whole blood sample

Publications (2)

Publication Number Publication Date
CN101467036A CN101467036A (zh) 2009-06-24
CN101467036B true CN101467036B (zh) 2013-06-19

Family

ID=37081679

Family Applications (1)

Application Number Title Priority Date Filing Date
CN2007800212732A Active CN101467036B (zh) 2006-06-06 2007-06-04 全血样品的差异溶血

Country Status (7)

Country Link
US (1) US7951598B2 (enExample)
EP (1) EP2032979B1 (enExample)
JP (1) JP5156738B2 (enExample)
CN (1) CN101467036B (enExample)
CA (1) CA2649633C (enExample)
ES (1) ES2690319T3 (enExample)
WO (1) WO2007140961A1 (enExample)

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JP5452383B2 (ja) * 2010-06-15 2014-03-26 株式会社日立ハイテクノロジーズ 生体試料前処理方法及び装置
BR112013001398A2 (pt) * 2010-08-11 2016-05-24 Kyowa Medex Co Ltd método, reagente e kit para medir hemoglobina glicada
US8486703B2 (en) 2010-09-30 2013-07-16 Ut-Battelle, Llc Surface sampling concentration and reaction probe
US8637813B2 (en) 2010-10-01 2014-01-28 Ut-Battelle, Llc System and method for laser assisted sample transfer to solution for chemical analysis
US8519330B2 (en) 2010-10-01 2013-08-27 Ut-Battelle, Llc Systems and methods for laser assisted sample transfer to solution for chemical analysis
US8409807B2 (en) 2010-10-22 2013-04-02 T2 Biosystems, Inc. NMR systems and methods for the rapid detection of analytes
BR112013010952B1 (pt) 2010-10-22 2020-08-25 T2 Biosystems, Inc. métodos para detectar a presença de um analito de ácido nucleico e uma espécie de candida em uma amostra líquida, para detectar a presença de um patógeno, um vírus e um ácido nucleico alvo em uma amostra de sangue total, e para amplificação de um ácido nucleico de patógeno alvo em uma amostra de sangue total, bem como sistema para a detecção de um ou mais analitos e cartucho removível dimensionado para facilitar inserção e remoção de um sistema
US8563298B2 (en) 2010-10-22 2013-10-22 T2 Biosystems, Inc. NMR systems and methods for the rapid detection of analytes
FI20115785A0 (fi) 2011-08-08 2011-08-08 Thermo Fisher Scientific Oy Menetelmä ja laite automaattiseen analyysiin
WO2013021101A1 (en) 2011-08-08 2013-02-14 Thermo Fisher Scientific Oy Method and apparatus for automated analysis
US9562271B2 (en) 2012-04-20 2017-02-07 T2 Biosystems, Inc. Compositions and methods for detection of Candida species
EP3391041B1 (en) * 2015-12-18 2019-10-16 H. Hoffnabb-La Roche Ag Automated clinical diagnostic system and method
CA3011901A1 (en) 2016-01-21 2017-07-27 T2 Biosystems, Inc. Nmr methods and systems for the rapid detection of bacteria
CN107561170B (zh) * 2016-07-02 2021-07-30 山东新时代药业有限公司 一种坦西莫司中间体的分析检测方法
CN106770747A (zh) * 2016-12-09 2017-05-31 广州迈达康医药科技有限公司 一种他克莫司制剂评价方法
CN110352062B (zh) * 2017-03-07 2024-04-02 豪夫迈·罗氏有限公司 免疫调节性大环内酯类的稳定制剂
CN116097093A (zh) * 2020-09-03 2023-05-09 生物辐射实验室股份有限公司 制备有核rbc(nrbc)类似物用作自动化血液分析仪中的参比血液对照
CN113325171B (zh) * 2021-08-02 2021-12-21 天津康博尔生物基因技术有限公司 检测人体红细胞叶酸含量的试剂盒、检测方法及用途
CN113776903A (zh) * 2021-08-27 2021-12-10 深圳市希莱恒医用电子有限公司 一种前处理试剂的制备方法、前处理试剂及前处理方法
WO2025119902A1 (en) * 2023-12-04 2025-06-12 F. Hoffmann-La Roche Ag Hemoglobin determination methods and systems

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Also Published As

Publication number Publication date
EP2032979B1 (en) 2018-07-18
US7951598B2 (en) 2011-05-31
WO2007140961A1 (en) 2007-12-13
JP5156738B2 (ja) 2013-03-06
EP2032979A1 (en) 2009-03-11
JP2009540274A (ja) 2009-11-19
CA2649633C (en) 2012-11-27
CN101467036A (zh) 2009-06-24
US20090253210A1 (en) 2009-10-08
WO2007140961A8 (en) 2008-11-06
CA2649633A1 (en) 2007-12-13
HK1134135A1 (en) 2010-04-16
ES2690319T3 (es) 2018-11-20

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