CN101449821A - Composition capable of releasing asthenopia and preparation method thereof - Google Patents

Composition capable of releasing asthenopia and preparation method thereof Download PDF

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Publication number
CN101449821A
CN101449821A CNA2007101785625A CN200710178562A CN101449821A CN 101449821 A CN101449821 A CN 101449821A CN A2007101785625 A CNA2007101785625 A CN A2007101785625A CN 200710178562 A CN200710178562 A CN 200710178562A CN 101449821 A CN101449821 A CN 101449821A
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China
Prior art keywords
asthenopia
composition
releasing function
extract
taurine
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Pending
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CNA2007101785625A
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Chinese (zh)
Inventor
范利平
张卫华
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Beijing Increase Pharmaceutical Technology Co Ltd
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Beijing Increase Pharmaceutical Technology Co Ltd
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Priority to CNA2007101785625A priority Critical patent/CN101449821A/en
Publication of CN101449821A publication Critical patent/CN101449821A/en
Pending legal-status Critical Current

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  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

The invention discloses a composition with asthenopia alleviation function and a preparation method of the same. The composition is prepared from raw materials of wolfberry extract, mulberry extract, taurine, chrysanthemum extract and pearl powder according to proper proportion and proper auxiliary materials, and can be prepared into any clinic acceptable dosage form such as tablet, capsule, particle, soft capsule and oral liquid.

Description

A kind of composition and method of making the same with asthenopia releasing function
Technical field
The present invention relates to a kind of composition and method of making the same with asthenopia releasing function.
Background technology
Visual fatigue (asthenopia) speech is derived by Hellenic representation, and original text means " weak eye " (eye is unable).Comprised " because of visual organ is attempted to obtain the syndrome that the autonomous effort of clear vision produces with not enough adjusting " according to the formulation visual fatigue of Duke one II der, and Suzumura is defined as the syndrome of one group of subjective symptom that produces when working with eyesight with visual fatigue, and these symptoms comprise: blurred vision, headache, epiphora, shoulder is stiff and feel sick etc.Existing most ophthalmology scholars think that this disease is the symptom based on the conscious eye of patient, the syndrome that eye or the organic factor of whole body and spirit (psychology) factor are interweaved.Thereby also often be called as kopiopia syndrome, belong to the psychosomatic medicine category.
Chrysanthemum is the dry capitulum of feverfew chrysanthemum (Chrysanthemum morifolium Ra.mat), is perennial herb, nature and flavor sweetness and bitterness, cold.The effect of have dispelling wind, heat-clearing, make eye bright, detoxifying.The antioxidation activity of the different extracts of chrysanthemum.The result shows that the Chrysan Yellow ketone compounds has the ability of removing hydroxy radical, superoxide anion, and stronger antioxidation activity is arranged, and finds that the chrysanthemum antioxidation activity is relevant with flavonoid content.
The fruit of Chinese wolfberry is the dry mature fruit of plant of Solanaceae lycium barbarum, has the effect of nourishing liver and kidney, benefiting shrewd head, moistening lung, is used for that consumptive disease is smart to be lost, soreness of waist and knee joint, and dizzy tinnitus, interior heat is quenched one's thirst, and the deficiency of blood is sallow, and blurred vision is not clear to wait disease.
Lycium barbarum is rich in carrotene, and carrotene can change vitamin A in human body.Vitamin A can promote the synthetic or regeneration of visual purple in the retina, keeps twenty-twenty vision.
Retina is a kind of special nerve fiber, and its content of taurine is high, and wherein the abundantest zone is the cellular regions that contains photoreceptor.The taurine that is in physiological level in retina has important function to the 26S Proteasome Structure and Function of keeping the visual cell.In vivo, in the retina under the taurine concentration general who has surrendered cause the photoreceptor structural damage, and unusual with serious visual function obstacle and electroretinogram.Behind the medicine that the supplementation of taurine or the obstruction taurine of stopping using absorb, it is normal that electroretinogram recovers.Have research to point out, fully taurine concentration reduces in the baby of parenteral alimentation, the children's blood plasma, some children occur together retinal structure, dysfunction.Improve after the supplementation of taurine.Discover that suitable supplementation of taurine and micronutrient can effectively improve low-light (level) occupational population night vision.Except that retina, crystalline lens, the blanket transparent body, optic nerve aixs cylinder also have relation with taurine.
Pearl contains rich nutrient contents and all kinds of life source material, specifically comprise: 1. amino acids: general fresh water pearl contains 18 kinds of amino acidses, comprise 7 kinds of human bodies and must need amino acid, i.e. serine, a word used in person's names propylhomoserin, methionine, isoleucine, leucine, tyrosine, phenylalanine, lysine.Wherein serine, a word used in person's names propylhomoserin etc. can be regulated human endocrine, strengthen immunity and anti-ageing.It is the important substance basis of pearl performance given efficacy.2. micro-: as about 22 kinds, to have important health-care efficacy.Can strengthen body immunity as selenium.3. calcium class: content is 38%~40%.4. taurine: be nonprotein amino acid.Can strengthen human body metabolism, and effects such as tranquilizing and allaying excitement are arranged.5. small molecule active peptide: the osculant product that produces during for hydrolyzed pearl albumen.Tool good health care effect.6. mouthful fore-telling quinoline and metal mouth are foretold quinoline: the tool anti-aging effects.7. vitamin B complex: content is abundant, effect significantly.8. other important component: as nucleic acid.
Mulberry fruit has the effect of filling liver kidney, benefiting essence-blood, is used for the treatment of that health due to the caused by liver and kidney deficiency is become thin, symptom such as soreness and weakness of waist and knees, seminal emission night sweat, dizzy, thirsty and dry pharynx.Mulberry fruit has the various active composition, and toxicity is little, has the adjustment body's immunity, promote hematopoietic cell growth, hypoglycemic, lipopenicillinase, hypotensive, protect effect such as liver.
Summary of the invention
The object of the invention is to provide a kind of composition with asthenopia releasing function.
Another purpose of wood invention is to provide a kind of preparation of compositions method with asthenopia releasing function.
The present invention is implemented by the following technical programs.
The present composition can be made by the raw material of following weight portion:
Fructus lycii P.E 200-600 Fructus Mori extract 900-1500 chrysanthemum extract 100-800 taurine 100-500 pearl powder 100-300.
The raw material of above-mentioned weight portion can be preferably: Fructus lycii P.E 300 Fructus Mori extracts 1000 chrysanthemum extracts 200 taurines 160 pearl powders 160.
The present invention has the composition of efficacy of relieving visual fatigue, also can add pharmaceutical necessities and make any clinical acceptable forms that comprises tablet, capsule, granule, oral liquid, and the auxiliary material weight portion can be 1000-18000.
Above-mentioned pharmaceutical necessities can comprise starch, lactose, dextrin, calcium sulfate, calcium carbonate, calcium monohydrogen phosphate, sodium carboxymethyl starch, xylitol, sweet mellow wine, sorbierite, microcrystalline cellulose, oil with hydrogenated soybean, olive oil, edible vegetable oil, beeswax, polyethylene glycol wherein one or more.
The fruit of Chinese wolfberry, chrysanthemum, mulberry fruit are all natural drug, adopt prior art three's extract of gained effect that all makes eye bright respectively.Three and taurine, pearl powder compatibility use, and raising immunity of organisms, 26S Proteasome Structure and Function anti-oxidant, that keep the visual cell are had important function.
Present composition functional trial is the result show, has the effect of alleviating asthenopia.
The specific embodiment
The present invention is described further by embodiment.
Embodiment 1
Get Fructus lycii P.E 200g, Fructus Mori extract 900g, chrysanthemum extract 100g, taurine 100g, pearl powder 300g, mix, add the 18000g lactose, make granule according to a conventional method.
Embodiment 2
Get Fructus lycii P.E 250g, Fructus Mori extract 940g, chrysanthemum extract 150g, taurine 110g, pearl powder 170g, mix, add the 1000g dextrin, make granule according to a conventional method.
Embodiment 3
Get Fructus lycii P.E 600g, Fructus Mori extract 1500g, chrysanthemum extract 800g, taurine 500g, pearl powder 100g, mix, add 1500g starch, make tablet according to a conventional method.
Embodiment 4
Get Fructus lycii P.E 470g, Fructus Mori extract 1100g, chrysanthemum extract 400g, taurine 300g, pearl powder 230g, mix, add the 900g microcrystalline cellulose, make tablet according to a conventional method.
Embodiment 5
Get Fructus lycii P.E 320g, Fructus Mori extract 1200g, chrysanthemum extract 200g, taurine 130g, pearl powder 150g, mix, add 1600g edible vegetable oil, beeswax 230g, heating stirs, and crosses 200 order colloid mills, and is standby;
Get gelatin 140g, glycerine 95g, distilled water 180g makes rubber according to a conventional method, and content is packed into is pressed into capsule and pill, through cold air drying, the washing surface oil reservoir, drying, quality inspection, packing, promptly.
Embodiment 6
Get Fructus lycii P.E 420g, Fructus Mori extract 1100g, chrysanthemum extract 600g, taurine 400g, pearl powder 188g, mix, mix, add 1300g calcium sulfate, make tablet according to a conventional method.

Claims (5)

1, a kind of composition with asthenopia releasing function is characterized in that being made by the raw material of following weight portion:
Fructus lycii P.E 200-600 Fructus Mori extract 900-1500 chrysanthemum extract 100-800 taurine 100-500 pearl powder 100-300.
2, the composition with asthenopia releasing function as claimed in claim 1 is characterized in that being made by the raw material of following weight portion:
Fructus lycii P.E 300 Fructus Mori extracts 1000 chrysanthemum extracts 200 taurines 160 pearl powders 160.
3, the composition that has asthenopia releasing function according to claim 1 is characterized in that also can adding the auxiliary material of 1000-18000 weight portion.
4, as having the preparation of compositions method of asthenopia releasing function as described in claim 1 or 3, it is characterized in that to add pharmaceutical necessities and make any clinical acceptable forms that comprises tablet, capsule, granule, soft capsule, oral liquid.
5, as having the preparation of compositions method of asthenopia releasing function as described in the claim 4, it is characterized in that pharmaceutical necessities can comprise starch, lactose, dextrin, calcium sulfate, calcium carbonate, calcium monohydrogen phosphate, sodium carboxymethyl starch, xylitol, sweet mellow wine, sorbierite, microcrystalline cellulose, oil with hydrogenated soybean, olive oil, edible vegetable oil, beeswax, polyethylene glycol wherein one or more.
CNA2007101785625A 2007-11-30 2007-11-30 Composition capable of releasing asthenopia and preparation method thereof Pending CN101449821A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CNA2007101785625A CN101449821A (en) 2007-11-30 2007-11-30 Composition capable of releasing asthenopia and preparation method thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CNA2007101785625A CN101449821A (en) 2007-11-30 2007-11-30 Composition capable of releasing asthenopia and preparation method thereof

Publications (1)

Publication Number Publication Date
CN101449821A true CN101449821A (en) 2009-06-10

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102512541A (en) * 2012-01-01 2012-06-27 山东大学威海分校 Compound mulberry preparation capable of improving superoxide dismutase activity
CN103652916A (en) * 2013-12-11 2014-03-26 罗永祺 Fructus lycii and Chinese yam chewing tablet and preparation method thereof
CN112931872A (en) * 2021-03-30 2021-06-11 宁夏职业技术学院(宁夏广播电视大学) Chewable soft capsule containing wolfberry and chrysanthemum and preparation method of chewable soft capsule

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102512541A (en) * 2012-01-01 2012-06-27 山东大学威海分校 Compound mulberry preparation capable of improving superoxide dismutase activity
CN102512541B (en) * 2012-01-01 2013-08-14 山东大学威海分校 Compound mulberry preparation capable of improving superoxide dismutase activity
CN103652916A (en) * 2013-12-11 2014-03-26 罗永祺 Fructus lycii and Chinese yam chewing tablet and preparation method thereof
CN103652916B (en) * 2013-12-11 2015-08-12 罗永祺 A kind of fruit of Chinese wolfberry Chinese yam chewable tablet and preparation method
CN112931872A (en) * 2021-03-30 2021-06-11 宁夏职业技术学院(宁夏广播电视大学) Chewable soft capsule containing wolfberry and chrysanthemum and preparation method of chewable soft capsule

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Open date: 20090610