CN101450098A - Medicine composition with asthenopia releasing function and preparation method thereof - Google Patents
Medicine composition with asthenopia releasing function and preparation method thereof Download PDFInfo
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- CN101450098A CN101450098A CNA2007101785589A CN200710178558A CN101450098A CN 101450098 A CN101450098 A CN 101450098A CN A2007101785589 A CNA2007101785589 A CN A2007101785589A CN 200710178558 A CN200710178558 A CN 200710178558A CN 101450098 A CN101450098 A CN 101450098A
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Abstract
The invention discloses a composition with asthenopia remitting function and preparation method thereof. The composition is made from the raw materials of tangerine extract, carotenol, beta-carotene and vitamin E according to a proper proportion and pharmaceutics acceptable auxiliary materials; it can be made into any clinic acceptable preparation form including tablet, capsule, grain, soft-capsule and oral liquid.
Description
Technical field
The present invention relates to a kind of composition and method of making the same with asthenopia releasing function.
Background technology
Asthenopia (asthenopia) speech is derived by Hellenic expression method, and original text means " weak eye " (eye is unable).Lifting manipulation according to Duke one II der, asthenopia has comprised " because of visual organ is attempted to obtain the syndrome that the autonomous effort of clear vision produces with insufficient adjusting ", and Suzumura is defined as the syndrome of one group of subjective symptom that produces when working with eyesight with asthenopia, and these symptoms comprise: blurred vision, headache, epiphora, shoulder is stiff and feel sick etc.Existing most ophthalmology scholars think that primary disease is the symptom based on the conscious eye of patient, the syndrome that eye or the organic factor of whole body and spirit (psychology) factor are interweaved, thereby also often be called as eyestrain's syndrome, belong to the psychosomatic medicine category.
Pericarpium Citri tangerinae is blue berry again, mainly grows in Europe, Russia, North America and Alps, and China has kind more than 90 approximately.Studies confirm that, the anthocyanidin that Pericarpium Citri tangerinae contains has stronger antioxidation, long-term edible can assist to remove toxic chemical substance, free radical etc. in the retina, increasing the retina C.I. Natural Red 8 generates, improve Infravision, the help eyes adapt to the variation of strong and weak light, take for a long time to make vision lasting.Can also strengthen blood capillary, improve blood circulation, weaken hematoblastic viscosity, prevent the generation of blood clot, strengthen cardio cerebral function.
Vitamin E can be protected polyvalent unsaturated fatty acid to avoid oxidation and destroy, and the peroxidating of lipid is brought out in prevention and prevention, reduces the generation of peroxidating material, keeps biomembranous normal configuration.
Modern study shows that vitamin E has stronger anti-radical action.The free radical resisting function of vitamin E is to have determined it to have reproducibility and lipophilic by himself mechanism (an active hydroxyl is arranged on phenyl ring, have reproducibility, secondly a saturated side chain is arranged on five carbocyclic rings).When free radical enters the fat phase, when chain reaction took place, vitamin E can play the effect of rapid Mulberry Extract.
Phylloxanthin (lutein) is the abundantest a kind of carotenoid that extensively is present in vegetable, fruit and some flowers.A large amount of phylloxanthin (lutein) in enrichment in people's the eyeball macula retinae, and these phylloxanthins (lutein) are believed to be helpful in and filter damaging blue light of eyes and the fine structure that prevents free radical destruction inside ofeye.Phylloxanthin has been proved to be an important Natural antioxidant.
Carotene can change vitamin A in human body, vitamin A can promote the synthetic or regeneration of rhodopsin in the retina, keeps twenty-twenty vision.
Summary of the invention
The object of the invention is to provide a kind of compositions with asthenopia releasing function.
Another purpose of the present invention is to provide a kind of preparation of compositions method with asthenopia releasing function.
The present invention is implemented by the following technical programs.
The present composition can be made by the raw material of following weight portion:
Pericarpium Citri tangerinae extract 200-700 phylloxanthin 5-20, beta-carotene 1-5, vitamin E 4-200.
The raw material of above-mentioned weight portion can be preferably: Pericarpium Citri tangerinae extract 300 phylloxanthins 10, beta-carotene 3, vitamin e1 0.
The present invention has the compositions of efficacy of relieving visual fatigue, also can add the oil with hydrogenated soybean of 400-800 weight portion.
The present invention has the preparation of compositions method of asthenopia releasing function, can take following steps:
(1) get Pericarpium Citri tangerinae extract, phylloxanthin, beta-carotene, vitamin E, oil with hydrogenated soybean mixing in proportion, stir, cross colloid mill, standby;
(2) make rubber according to a conventional method, content is packed into is pressed into soft gelatin capsule, through cold air drying, and the washing surface oil reservoir, drying, promptly.
Also can add suitable pharmaceutical necessities in the present composition raw material and make any clinical acceptable forms that comprises tablet, capsule, granule, oral liquid.Pharmaceutical necessities can comprise starch, lactose, dextrin, calcium sulfate, calcium carbonate, calcium hydrogen phosphate, carboxymethyl starch sodium, xylitol, mannitol, sorbitol, microcrystalline Cellulose, oil with hydrogenated soybean, olive oil, edible vegetable oil, Polyethylene Glycol wherein one or more.
The proanthocyanidin that the Pericarpium Citri tangerinae extract that adopts prior art to make contains has stronger antioxidant action, and alleviating asthenopia is had obvious effect.Carotene changes the synthetic or regeneration that vitamin A can promote rhodopsin in the retina in human body, keep twenty-twenty vision.Dimension E tool antioxidation.Phylloxanthin has antioxidation and protection has effect to retina.Health food of the present invention uses with above-mentioned material combination, the energy Synergistic, and rhodopsin synthesizes the protection retina in antioxidation and the promotion retina.
Present composition functional trial is the result show, has the effect of alleviating asthenopia.
The specific embodiment
The present invention is described further by embodiment.
Embodiment 1
Get Pericarpium Citri tangerinae extract 200g phylloxanthin 5g, beta-carotene 1g, vitamin E 4g, edible vegetable oil 800g, mix, stir, cross 200 order colloid mills, standby;
Get gelatin 130g, glycerol 90g, distilled water 140g makes rubber according to a conventional method, and content is packed into is pressed into soft gelatin capsule, through cold air drying, the washing surface oil reservoir, drying, quality inspection, packing, promptly.
Embodiment 2
Get Pericarpium Citri tangerinae extract 700g phylloxanthin 20g, beta-carotene 5g, vitamin E2 00g, oil with hydrogenated soybean 400g, mix, stir, cross 200 order colloid mills, standby;
Get gelatin 300g, glycerol 150g, distilled water 340g makes rubber according to a conventional method, and content is packed into is pressed into soft gelatin capsule, through cold air drying, the washing surface oil reservoir, drying, quality inspection, packing, promptly.
Embodiment 3
Get Pericarpium Citri tangerinae extract 400g phylloxanthin 10g, beta-carotene 3g, vitamin e1 00g, oil with hydrogenated soybean 600g, mix, stir, cross 200 order colloid mills, standby;
Get gelatin 220g, glycerol 160g, distilled water 280g makes rubber according to a conventional method, and content is packed into is pressed into soft gelatin capsule, through cold air drying, the washing surface oil reservoir, drying, quality inspection, packing, promptly.
Embodiment 4
Get Pericarpium Citri tangerinae extract 300g phylloxanthin 8g, beta-carotene 4g, vitamin E 90g lactose 180g, mix, stir, make capsule according to a conventional method promptly.
Embodiment 5
Get Pericarpium Citri tangerinae extract 570g phylloxanthin 9g, beta-carotene 2g, vitamin e1 10g microcrystalline Cellulose 200g, mix, stir, make tablet according to a conventional method promptly.
Claims (6)
1, a kind of compositions with asthenopia releasing function is characterized in that being made by the raw material of following weight portion:
Pericarpium Citri tangerinae extract 200-700 phylloxanthin 5-20, beta-carotene 1-5, vitamin E 4-200.
2, the compositions that has asthenopia releasing function according to claim 1 is characterized in that being made by the raw material of following weight portion:
Pericarpium Citri tangerinae extract 300 phylloxanthins 10, beta-carotene 3, vitamin E 10.
3, the compositions that has asthenopia releasing function according to claim 1 is characterized in that also can adding the oil with hydrogenated soybean of 400-800 weight portion.
4, as having the preparation of compositions method of asthenopia releasing function as described in claim 1 or 3, it is characterized in that comprising the steps:
(1) get Pericarpium Citri tangerinae extract, phylloxanthin, beta-carotene, vitamin E, oil with hydrogenated soybean mixing in proportion, stir, cross colloid mill, standby;
(2) make rubber according to a conventional method, content is packed into is pressed into soft gelatin capsule, through cold air drying, and the washing surface oil reservoir, drying, promptly.
5, the preparation of compositions method that has asthenopia releasing function according to claim 1 is characterized in that also can adding pharmaceutical necessities and makes any clinical acceptable forms that comprises tablet, capsule, granule, oral liquid.
6, as having the preparation of compositions method of asthenopia releasing function as described in claim 1 or 5, it is characterized in that pharmaceutical necessities can comprise starch, lactose, dextrin, calcium sulfate, calcium carbonate, calcium hydrogen phosphate, carboxymethyl starch sodium, xylitol, mannitol, sorbitol, microcrystalline Cellulose, oil with hydrogenated soybean, olive oil, edible vegetable oil, Polyethylene Glycol wherein one or more.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNA2007101785589A CN101450098A (en) | 2007-11-30 | 2007-11-30 | Medicine composition with asthenopia releasing function and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNA2007101785589A CN101450098A (en) | 2007-11-30 | 2007-11-30 | Medicine composition with asthenopia releasing function and preparation method thereof |
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| Publication Number | Publication Date |
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| CN101450098A true CN101450098A (en) | 2009-06-10 |
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| Application Number | Title | Priority Date | Filing Date |
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| CNA2007101785589A Pending CN101450098A (en) | 2007-11-30 | 2007-11-30 | Medicine composition with asthenopia releasing function and preparation method thereof |
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Cited By (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101904502A (en) * | 2010-08-03 | 2010-12-08 | 晨光生物科技集团天津有限公司 | Compound xanthophyll soft capsule and preparation method |
| CN102318851A (en) * | 2011-07-27 | 2012-01-18 | 陈家亮 | Lutein drink and preparation method thereof |
| CN102318850A (en) * | 2011-07-27 | 2012-01-18 | 陈家亮 | Lutein drink |
| CN102763847A (en) * | 2012-08-10 | 2012-11-07 | 广东太阳神集团有限公司 | Health-care food with function of relieving visual fatigue and preparation method thereof |
| CN102960738A (en) * | 2012-12-20 | 2013-03-13 | 汤臣倍健股份有限公司 | Bilberry and lutein soft capsule and preparation method thereof |
| CN104824644A (en) * | 2015-05-13 | 2015-08-12 | 宁波北仑戌鸿农业科技有限公司 | Food suitable for vision protection |
| CN105077260A (en) * | 2015-09-22 | 2015-11-25 | 哈尔滨宝德生物技术股份有限公司 | Xylitol and lutein granule capable of relieving eyestrain and preparation method of xylitol and lutein granule |
| CN106265850A (en) * | 2015-06-02 | 2017-01-04 | 浙江爱生药业有限公司 | Asthenopic drug combination preparation of a kind of alleviation and preparation method thereof |
| CN111991437A (en) * | 2020-10-10 | 2020-11-27 | 环贯绿佳利(珠海)科技发展有限公司 | Formula and preparation method of soft capsule for protecting eyesight |
| CN114288347A (en) * | 2021-12-27 | 2022-04-08 | 济宁医学院 | Medicine and food composition for benefiting eyesight and improving eyesight and preparation method and application method thereof |
-
2007
- 2007-11-30 CN CNA2007101785589A patent/CN101450098A/en active Pending
Cited By (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101904502B (en) * | 2010-08-03 | 2013-04-24 | 晨光生物科技集团天津有限公司 | Compound xanthophyll soft capsule and preparation method |
| CN101904502A (en) * | 2010-08-03 | 2010-12-08 | 晨光生物科技集团天津有限公司 | Compound xanthophyll soft capsule and preparation method |
| CN102318851A (en) * | 2011-07-27 | 2012-01-18 | 陈家亮 | Lutein drink and preparation method thereof |
| CN102318850A (en) * | 2011-07-27 | 2012-01-18 | 陈家亮 | Lutein drink |
| CN102318851B (en) * | 2011-07-27 | 2012-12-26 | 迪视康（厦门）生物科技有限公司 | Lutein drink and preparation method thereof |
| CN102763847A (en) * | 2012-08-10 | 2012-11-07 | 广东太阳神集团有限公司 | Health-care food with function of relieving visual fatigue and preparation method thereof |
| CN102763847B (en) * | 2012-08-10 | 2014-04-02 | 广东太阳神集团有限公司 | Health-care food with function of relieving visual fatigue and preparation method thereof |
| CN102960738A (en) * | 2012-12-20 | 2013-03-13 | 汤臣倍健股份有限公司 | Bilberry and lutein soft capsule and preparation method thereof |
| CN104824644A (en) * | 2015-05-13 | 2015-08-12 | 宁波北仑戌鸿农业科技有限公司 | Food suitable for vision protection |
| CN106265850A (en) * | 2015-06-02 | 2017-01-04 | 浙江爱生药业有限公司 | Asthenopic drug combination preparation of a kind of alleviation and preparation method thereof |
| CN105077260A (en) * | 2015-09-22 | 2015-11-25 | 哈尔滨宝德生物技术股份有限公司 | Xylitol and lutein granule capable of relieving eyestrain and preparation method of xylitol and lutein granule |
| CN111991437A (en) * | 2020-10-10 | 2020-11-27 | 环贯绿佳利(珠海)科技发展有限公司 | Formula and preparation method of soft capsule for protecting eyesight |
| CN114288347A (en) * | 2021-12-27 | 2022-04-08 | 济宁医学院 | Medicine and food composition for benefiting eyesight and improving eyesight and preparation method and application method thereof |
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Open date: 20090610 |