CN101433638A - Composition with function for alleviating eyestrain and preparation method thereof - Google Patents
Composition with function for alleviating eyestrain and preparation method thereof Download PDFInfo
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- CN101433638A CN101433638A CNA2007101774993A CN200710177499A CN101433638A CN 101433638 A CN101433638 A CN 101433638A CN A2007101774993 A CNA2007101774993 A CN A2007101774993A CN 200710177499 A CN200710177499 A CN 200710177499A CN 101433638 A CN101433638 A CN 101433638A
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Abstract
The invention discloses a composition with the efficacy of relieving visual fatigue and a preparation method thereof. The composition can be prepared into clinically accepted formulations such as tablets, capsules, granules, soft capsules, and oral liquids by taking a cowberry extract, a folium ginkgo extract, a grape seed extract, a medlar extract and a Semen Cassiae extract as raw materials which are combined according to the proper proportion and adding pharmaceutically accepted auxiliary materials.
Description
Technical field
The present invention relates to a kind of composition and method of making the same with efficacy of relieving visual fatigue.
Background technology
Asthenopia (asthenopia) speech is derived by Hellenic expression method, and original text means " weak eye " (eye is unable).Comprised " because of visual organ is attempted to obtain the syndrome that the autonomous effort of clear vision produces with insufficient adjusting " according to the lifting manipulation asthenopia of Duke-II der.And Suzumura is defined as the syndrome of one group of subjective symptom that produces when working with eyesight with asthenopia, and these symptoms comprise: blurred vision, headache, epiphora, shoulder is stiff and feel sick etc.Existing most ophthalmology scholars think that primary disease is the symptom based on the conscious eye of patient, the syndrome that eye or the organic factor of whole body and spirit (psychology) factor are interweaved.Thereby also often be called as eyestrain's syndrome, belong to the psychosomatic medicine category.
Pericarpium Citri tangerinae is blue berry again, mainly grows in Europe, Russia, North America and Alps, and China has kind more than 90 approximately.Studies confirm that, the anthocyanidin that Pericarpium Citri tangerinae contains has stronger antioxidant action, long-term edible can assist to remove toxic chemical substance, free radical etc. in the retina, increasing the retina C.I. Natural Red 8 generates, improve Infravision, the help eyes adapt to the variation of strong and weak light, take for a long time to make vision lasting.Can also strengthen blood capillary, improve blood circulation, weaken hematoblastic viscosity, prevent the generation of blood clot, strengthen cardio cerebral function.
The Folium Ginkgo chemical constituent is very complicated, and main chemical compositions is flavonoid and terpene lactones chemical compound, contains polyprenol, organic acid, polysaccharide, aminoacid, phenols and trace element etc. in addition.According to incompletely statistics, from Folium Ginkgo, isolate chemical compound have 140 surplus kind, flavone compound and terpene lactones chemical compound are two kinds of main active of Folium Ginkgo.Folium Ginkgo extract increases the eyeball capillary blood flow in addition, alleviates the eyestrain and prevents effect such as retinopathy.Strengthen the blood circulation of eyes and whole body.Keep healthy intraocular pressure.Strengthen healthy histamine response.
Medical circle generally believes that eyes will constantly overcome fluctuation intraocular pressure resistance to regulate the optic nerve blood flow rate when carrying out normal physiological activity.Folium Ginkgo extract energy improvement maincenter and peripheral blood flow reset vasospasm, reduce apoptosis, but it does not influence intraocular pressure, and glaucoma treatment is had assosting effect.Radical reaction enzyme activity can be participated in and regulate to Flavonoid substances also, as superoxide dismutase (SOD), glutathione peroxidase (GSG.PX) etc. except that stopping free chain reaction.EGB antioxidation even surpass VE, and have free radical resisting and attack character external.Have data to prove: EGB effectively antagonism free radical causes polyunsaturated fatty acid oxidation and protecting film albumen to avoid the irreversibility polymerization that these catabolites cause.
Contain a kind of outstanding bioflavonoids polymer in the Semen Vitis viniferae, structurally belong to proanthocyanidins, be called compound proanthocyanidin, have the effect of powerful removing free radical (free radical).Scientist all over the world is consistent to be thought: its achievement is an oxidation resistance the most superpower on the medical history of world, and its effectiveness is ascorbic 20 times, 50 times of vitamin E.The Semen Vitis viniferae proanthocyanidin has obvious effect to improving eye the vision tired and myope.
Fructus Lycii is the dry mature fruit of plant of Solanaceae lycium barbarum, has the effect of nourishing the liver and kidney, replenishing vital essence to improve eyesight, lung moistening, is used for the asthenia damage of essence, soreness of waist and knee joint, and vertigo and tinnitus, interior-heat is quenched one's thirst, blood deficiency and yellow complexion, the not clear grade of blurred vision disease.
Lycium barbarum L. is rich in carotene, and carotene can change vitamin A in human body.Vitamin A can promote the synthetic or regeneration of rhodopsin in the retina, keeps twenty-twenty vision.
Semen Cassiae liver heat removing and making eye bright.Semen Cassiae contains Semen Cassiae element, Semen Cassiae lactone, chrysophanol, physcione, and optic nerve is had protective effect, and can reduce intraocular pressure, and cataract, glaucoma are had therapeutical effect with conjunctivitis etc.Shennong's Herbal day: " Semen Cassiae obeys for a long time that benefit is with nothing left, and tonifying YIN expels the heat-evil, the gas of big invigorating the liver and kidney due to also ".Semen Cassiae can be let out the liver and gall stagnated fire clearly, again can dispelling wind and heat pathogens, and be treatment conjunctival congestion and swelling pain key medicine.
Summary of the invention
The object of the invention is to provide a kind of compositions with efficacy of relieving visual fatigue.
Another purpose of the present invention is to provide a kind of preparation of compositions method of efficacy of relieving visual fatigue.
The present invention is implemented by the following technical programs.
The present composition can be led by the raw material of following weight portion and make:
Pericarpium Citri tangerinae extract 0.1-0.6, Folium Ginkgo extract 0.1-0.7, Semen Vitis viniferae extract 0.1-0.6, Fructus Lycii extract 0.05-0.9, Semen Cassiae extract 0.1-0.9.
The present composition also can be made by the raw material of following weight portion: Pericarpium Citri tangerinae extract 0.25, Folium Ginkgo extract 0.33, Semen Vitis viniferae extract 0.24, Fructus Lycii extract 0.2, Semen Cassiae extract 0.3.
The present composition adds pharmaceutical necessities and makes clinical acceptable forms such as tablet, capsule, granule, soft capsule, oral liquid.
In the present composition preparation method pharmaceutical necessities can be shallow lake starch, lactose, dextrin, calcium sulfate, calcium carbonate, calcium hydrogen phosphate, carboxymethyl starch sodium, xylitol, mannitol, sorbitol, microcrystalline Cellulose, soybean oil, olive oil, Polyethylene Glycol wherein one or more.
The proanthocyanidin that Pericarpium Citri tangerinae extract and Semen Vitis viniferae extract contain has stronger antioxidant action, and alleviating asthenopia is had obvious effect.Folium Ginkgo extract has antioxidation, efficacy of relieving visual fatigue.The Fructus Lycii extract that adopts conventional extracting method to make has nourishing the liver and kidney, replenishing vital essence to improve eyesight effect, and contained carotene changes vitamin A in human body.Vitamin A can promote the synthetic or regeneration of rhodopsin in the retina, keeps twenty-twenty vision.Adopt the conventional Semen Cassiae extract that makes to have liver heat removing and eyesight improving effect clearly, and institute contains active component, optic nerve is had protective effect, and can reduce intraocular pressure.The present composition uses with above-mentioned material combination, can Synergistic.
Present composition functional trial is the result show, has the effect of alleviating asthenopia.
The specific embodiment
The present invention is described further by embodiment.
Embodiment 1
Get Pericarpium Citri tangerinae extract 100g, Folium Ginkgo extract 100g, Semen Vitis viniferae extract 100g, Fructus Lycii extract 50g, Semen Cassiae extract 900g adds 800g calcium sulfate, makes capsule according to a conventional method.
Embodiment 2
Get Pericarpium Citri tangerinae extract 600g, Folium Ginkgo extract 700g, Semen Vitis viniferae extract 600g, Fructus Lycii extract 900g, Semen Cassiae extract 100g adds carboxymethyl starch sodium 200g, and lactose 100g makes tablet according to a conventional method.
Embodiment 3
Get Pericarpium Citri tangerinae extract 300g, Folium Ginkgo extracts 420g, Semen Vitis viniferae extract 413g, and Fructus Lycii extract 600g, Semen Cassiae extract 600g adds lactose 1800g, makes granule according to a conventional method.
Embodiment 4
Get Pericarpium Citri tangerinae extract 270g, Folium Ginkgo extract 530g, Semen Vitis viniferae extract 710g, Fructus Lycii extract 630g adds Macrogol 4000 960g, makes soft capsule according to a conventional method.
Claims (4)
1, a kind of compositions with efficacy of relieving visual fatigue is characterized in that mainly being made by the raw material of following weight portion: Pericarpium Citri tangerinae extract 0.1-0.6, Folium Ginkgo extract 0.1-0.7, Semen Vitis viniferae extract 0.1-0.6, Fructus Lycii extract 0.05-0.9, Semen Cassiae extract 0.1-0.9.
2, compositions as claimed in claim 1 is characterized in that being made by the raw material of following weight portion: Pericarpium Citri tangerinae extract 0.25, Folium Ginkgo extract 0.33, Semen Vitis viniferae extract 0.24, Fructus Lycii extract 0.2, Semen Cassiae extract 0.3.
3, the described preparation of compositions method of claim 1 is characterized in that adding pharmaceutical necessities and makes clinical acceptable forms, comprises tablet, capsule, granule, soft capsule, oral liquid.
4, as preparation of compositions method as described in the claim 3, it is characterized in that pharmaceutical necessities comprise starch, lactose, dextrin, calcium sulfate, calcium carbonate, calcium hydrogen phosphate, carboxymethyl starch sodium, xylitol, mannitol, sorbitol, microcrystalline Cellulose, soybean oil, olive oil, Polyethylene Glycol wherein one or more.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNA2007101774993A CN101433638A (en) | 2007-11-16 | 2007-11-16 | Composition with function for alleviating eyestrain and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNA2007101774993A CN101433638A (en) | 2007-11-16 | 2007-11-16 | Composition with function for alleviating eyestrain and preparation method thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN101433638A true CN101433638A (en) | 2009-05-20 |
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| Application Number | Title | Priority Date | Filing Date |
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| CNA2007101774993A Pending CN101433638A (en) | 2007-11-16 | 2007-11-16 | Composition with function for alleviating eyestrain and preparation method thereof |
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103989809A (en) * | 2014-06-17 | 2014-08-20 | 史克勇 | Health-care product and preparation method thereof |
| CN103989821A (en) * | 2014-06-17 | 2014-08-20 | 史克勇 | Traditional Chinese medicine composition for improving asthenopia |
| CN104000201A (en) * | 2014-06-17 | 2014-08-27 | 史克勇 | Heath-care food capable of relieving visual fatigue |
| CN107213271A (en) * | 2017-05-31 | 2017-09-29 | 江苏朸健生命科技发展有限公司 | One kind alleviates asthenopia tablet and preparation method thereof |
-
2007
- 2007-11-16 CN CNA2007101774993A patent/CN101433638A/en active Pending
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103989809A (en) * | 2014-06-17 | 2014-08-20 | 史克勇 | Health-care product and preparation method thereof |
| CN103989821A (en) * | 2014-06-17 | 2014-08-20 | 史克勇 | Traditional Chinese medicine composition for improving asthenopia |
| CN104000201A (en) * | 2014-06-17 | 2014-08-27 | 史克勇 | Heath-care food capable of relieving visual fatigue |
| CN107213271A (en) * | 2017-05-31 | 2017-09-29 | 江苏朸健生命科技发展有限公司 | One kind alleviates asthenopia tablet and preparation method thereof |
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| Date | Code | Title | Description |
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| C06 | Publication | ||
| PB01 | Publication | ||
| C02 | Deemed withdrawal of patent application after publication (patent law 2001) | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Open date: 20090520 |