CN101433637A - Composition with function for alleviating eyestrain and preparation method thereof - Google Patents
Composition with function for alleviating eyestrain and preparation method thereof Download PDFInfo
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- CN101433637A CN101433637A CNA2007101774989A CN200710177498A CN101433637A CN 101433637 A CN101433637 A CN 101433637A CN A2007101774989 A CNA2007101774989 A CN A2007101774989A CN 200710177498 A CN200710177498 A CN 200710177498A CN 101433637 A CN101433637 A CN 101433637A
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- folium ginkgo
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Abstract
The invention discloses a composition with the efficacy of relieving visual fatigue and a preparation method thereof. The composition can be prepared into clinically accepted formulations such as tablets, capsules, granules, soft capsules, and oral liquids by taking a cowberry extract, a folium ginkgo extract, a grape seed extract, and a medlar extract as raw materials which are combined according to the proper proportion and adding pharmaceutically accepted auxiliary materials.
Description
Technical field
The present invention relates to a kind of composition and method of making the same with efficacy of relieving visual fatigue.
Background technology
Asthenopia (asthenopia) speech is derived by Hellenic expression method, and original text means " weak eye " (eye is unable).Comprised " because of visual organ is attempted to obtain the syndrome that the autonomous effort of clear vision produces with insufficient adjusting " according to the lifting manipulation asthenopia of Duke one II der.And Suzumura is defined as the syndrome of one group of subjective symptom that produces when working with eyesight with asthenopia, and these symptoms comprise: blurred vision, headache, epiphora, shoulder is stiff and feel sick etc.Existing most ophthalmology scholars think that primary disease is the symptom based on the conscious eye of patient, the syndrome that eye or the organic factor of whole body and spirit (psychology) factor are interweaved.Thereby also often be called as eyestrain's syndrome, belong to the psychosomatic medicine category.
Pericarpium Citri tangerinae is blue berry again, mainly grows in Europe, Russia, North America and Alps, and China has kind more than 90 approximately.Studies confirm that, the anthocyanidin that Pericarpium Citri tangerinae contains has stronger antioxidant action, long-term edible can assist to remove toxic chemical substance, free radical etc. in the retina, increasing the retina C.I. Natural Red 8 generates, improve Infravision, the help eyes adapt to the variation of strong and weak light, take for a long time to make vision lasting.Can also strengthen blood capillary, improve blood circulation, weaken hematoblastic viscosity, prevent the generation of blood clot, strengthen cardio cerebral function.
The Folium Ginkgo chemical constituent is very complicated, and main chemical compositions is flavonoid and terpene lactones chemical compound, contains polyprenol, organic acid, polysaccharide, aminoacid, phenols and trace element etc. in addition.According to incompletely statistics, from Folium Ginkgo, isolate chemical compound have 140 surplus kind, flavone compound and terpene lactones chemical compound are two kinds of main active of Folium Ginkgo.Folium Ginkgo extract increases the eyeball capillary blood flow in addition, alleviates the eyestrain and prevents effect such as retinopathy.Strengthen the blood circulation of eyes and whole body.Keep healthy intraocular pressure.Strengthen healthy histamine response.
Medical circle generally believes that eyes will constantly overcome fluctuation intraocular pressure resistance to regulate the optic nerve blood flow rate when carrying out normal physiological activity.Folium Ginkgo extract energy improvement maincenter and peripheral blood flow reset vasospasm, reduce apoptosis, but it does not influence intraocular pressure, and glaucoma treatment is had assosting effect.Radical reaction enzyme activity can be participated in and regulate to Flavonoid substances also, as superoxide dismutase (SOD), glutathione peroxidase (GSG.PX) etc. except that stopping free chain reaction.EGB。Antioxidation even surpass VE, and have free radical resisting and attack character external.Have data to prove: EGB.Effectively the antagonism free radical causes polyunsaturated fatty acid oxidation and protecting film albumen to avoid the irreversibility polymerization that these catabolites cause.
Contain a kind of outstanding bioflavonoids polymer in the Semen Vitis viniferae, structurally belong to proanthocyanidins, be called compound proanthocyanidin, have the effect of powerful removing free radical (free radical).Scientist all over the world is consistent to be thought: its achievement is an oxidation resistance the most superpower on the medical history of world, and its effectiveness is ascorbic 20 times, 50 times of vitamin E.The Semen Vitis viniferae proanthocyanidin has obvious effect to improving eye the vision tired and myope.
Fructus Lycii is the dry mature fruit of plant of Solanaceae lycium barbarum, has the effect of nourishing the liver and kidney, replenishing vital essence to improve eyesight, lung moistening, is used for the asthenia damage of essence, soreness of waist and knee joint, and vertigo and tinnitus, interior-heat is quenched one's thirst, blood deficiency and yellow complexion, the not clear grade of blurred vision disease.
Lycium barbarum L. is rich in carotene, and carotene can change vitamin A in human body.Vitamin A can promote the synthetic or regeneration of rhodopsin in the retina, keeps twenty-twenty vision.
Summary of the invention
The object of the invention is to provide a kind of compositions with efficacy of relieving visual fatigue.
Another purpose of the present invention is to provide a kind of preparation of compositions method of efficacy of relieving visual fatigue.
The present invention is implemented by the following technical programs.
The present composition can be led by the raw material of following weight portion and make:
Pericarpium Citri tangerinae extract 0.1-0.8, Folium Ginkgo extract 0.1-0.5, Semen Vitis viniferae extract 0.1-0.6, Fructus Lycii extract 0.05-0.9.
The present composition also can be made by the raw material of following weight portion: Pericarpium Citri tangerinae extract 0.3, Folium Ginkgo extract 0.3, Semen Vitis viniferae extract 0.2, Fructus Lycii extract 0.1.
The present composition adds pharmaceutical necessities and makes clinical acceptable forms such as tablet, capsule, granule, soft capsule, oral liquid.
Pharmaceutical necessities can be in the present composition preparation method: starch, lactose, dextrin, carboxymethyl starch sodium, xylitol, mannitol, sorbitol, microcrystalline Cellulose, soybean oil, olive oil wherein one or more.
The proanthocyanidin that Pericarpium Citri tangerinae extract and Semen Vitis viniferae extract contain has stronger antioxidant action, and alleviating asthenopia is had obvious effect.Folium Ginkgo extract has antioxidation, efficacy of relieving visual fatigue.The Fructus Lycii extract that adopts conventional extracting method to make has nourishing the liver and kidney, replenishing vital essence to improve eyesight effect, and contained carotene changes vitamin A in human body.Vitamin A can promote the synthetic or regeneration of rhodopsin in the retina, keeps twenty-twenty vision.The present composition uses with above-mentioned material combination, can Synergistic.
Present composition functional trial is the result show, has the effect of alleviating asthenopia.
The specific embodiment
Embodiment 1
Get Pericarpium Citri tangerinae extract 100g, Folium Ginkgo extract 100g, Semen Vitis viniferae extract 100g, Fructus Lycii extract 900g adds lactose 1000g, makes capsule according to a conventional method.
Embodiment 2
Get Pericarpium Citri tangerinae extract 800g, Folium Ginkgo extract 500g, Semen Vitis viniferae extract 600g, Fructus Lycii extract 50g adds microcrystalline Cellulose 400g, makes tablet according to a conventional method.
Embodiment 3
Get Pericarpium Citri tangerinae extract 400g, Folium Ginkgo extracts 300g, Semen Vitis viniferae extract 400g, and Fructus Lycii extract 500g adds starch 500g, makes tablet according to a conventional method.
Embodiment 5
Get Pericarpium Citri tangerinae extract 340g, Folium Ginkgo extract 410g, Semen Vitis viniferae extract 380g, Fructus Lycii extract 600g adds lactose 1100g, makes capsule according to a conventional method.
Embodiment 6
Get Pericarpium Citri tangerinae extract 310g, Folium Ginkgo extract 280g, Semen Vitis viniferae extract 190g, Semen Cassiae extract 220g adds Semen sojae atricolor 1200g, makes soft capsule according to a conventional method.
Embodiment 7
Get Pericarpium Citri tangerinae extract 790g, Folium Ginkgo extract 487g, Semen Vitis viniferae extract 590, Semen Cassiae extract 820g adds lactose 2600g, makes granule according to a conventional method.
Claims (4)
1, a kind of compositions with efficacy of relieving visual fatigue is characterized in that mainly being made by the raw material of following weight portion: Pericarpium Citri tangerinae extract 0.1-0.8, Folium Ginkgo extract 0.1-0.5, Semen Vitis viniferae extract 0.1-0.6, Fructus Lycii extract 0.05-0.9.
2, compositions as claimed in claim 1 is characterized in that being made by the raw material of following weight portion: Pericarpium Citri tangerinae extract 0.3, Folium Ginkgo extract 0.3, Semen Vitis viniferae extract 0.2, Fructus Lycii extract 0.1.
3, the described preparation of compositions method of claim 1 is characterized in that adding pharmaceutical necessities and makes clinical acceptable forms, comprises tablet, capsule, granule, soft capsule, oral liquid.
4, as preparation of compositions method as described in the claim 3, it is characterized in that in this method the medicament accessory package draw together starch, lactose, dextrin, carboxymethyl starch sodium, xylitol, mannitol, sorbitol, microcrystalline Cellulose, soybean oil, olive oil wherein one or more.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNA2007101774989A CN101433637A (en) | 2007-11-16 | 2007-11-16 | Composition with function for alleviating eyestrain and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNA2007101774989A CN101433637A (en) | 2007-11-16 | 2007-11-16 | Composition with function for alleviating eyestrain and preparation method thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN101433637A true CN101433637A (en) | 2009-05-20 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNA2007101774989A Pending CN101433637A (en) | 2007-11-16 | 2007-11-16 | Composition with function for alleviating eyestrain and preparation method thereof |
Country Status (1)
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| CN (1) | CN101433637A (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103110096A (en) * | 2012-12-26 | 2013-05-22 | 东莞市照燕生物科技有限公司 | Nutritional health-care product capable of alleviating eyestrain and improving eyesight |
| CN107569578A (en) * | 2017-09-30 | 2018-01-12 | 美可高特羊乳有限公司 | It is a kind of that there is sheep breast composition for alleviating kopiopia effect and preparation method thereof |
| CN108669333A (en) * | 2018-04-17 | 2018-10-19 | 佛山市雷米高动物营养保健科技有限公司 | Except pet tear stains composition, except pet tear stains product and preparation method thereof |
-
2007
- 2007-11-16 CN CNA2007101774989A patent/CN101433637A/en active Pending
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103110096A (en) * | 2012-12-26 | 2013-05-22 | 东莞市照燕生物科技有限公司 | Nutritional health-care product capable of alleviating eyestrain and improving eyesight |
| CN107569578A (en) * | 2017-09-30 | 2018-01-12 | 美可高特羊乳有限公司 | It is a kind of that there is sheep breast composition for alleviating kopiopia effect and preparation method thereof |
| CN108669333A (en) * | 2018-04-17 | 2018-10-19 | 佛山市雷米高动物营养保健科技有限公司 | Except pet tear stains composition, except pet tear stains product and preparation method thereof |
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| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C02 | Deemed withdrawal of patent application after publication (patent law 2001) | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Open date: 20090520 |