CN101449820A - Composition capable of releasing asthenopia and preparation method thereof - Google Patents

Composition capable of releasing asthenopia and preparation method thereof Download PDF

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Publication number
CN101449820A
CN101449820A CNA2007101785610A CN200710178561A CN101449820A CN 101449820 A CN101449820 A CN 101449820A CN A2007101785610 A CNA2007101785610 A CN A2007101785610A CN 200710178561 A CN200710178561 A CN 200710178561A CN 101449820 A CN101449820 A CN 101449820A
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China
Prior art keywords
composition
asthenopia
taurine
releasing function
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CNA2007101785610A
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Chinese (zh)
Inventor
谭剑平
张卫华
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Beijing Increase Pharmaceutical Technology Co Ltd
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Beijing Increase Pharmaceutical Technology Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Application filed by Beijing Increase Pharmaceutical Technology Co Ltd filed Critical Beijing Increase Pharmaceutical Technology Co Ltd
Priority to CNA2007101785610A priority Critical patent/CN101449820A/en
Publication of CN101449820A publication Critical patent/CN101449820A/en
Pending legal-status Critical Current

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  • Medicinal Preparation (AREA)

Abstract

The invention discloses a composition with asthenopia alleviation function and a preparation method of the same. The composition is prepared from raw materials of cowberry extract, wolfberry extract, taurine and soybean phosphatide according to proper proportion and proper auxiliary materials, and can be prepared into any clinic acceptable dosage form such as tablet, capsule, particle, soft capsule and oral liquid.

Description

A kind of composition and method of making the same with asthenopia releasing function
Technical field
The present invention relates to a kind of composition and method of making the same with asthenopia releasing function.
Background technology
Visual fatigue (asthenopia) speech is derived by Hellenic representation, and original text means " weak eye " (eye is unable).Comprised " because of visual organ is attempted to obtain the syndrome that the autonomous effort of clear vision produces with not enough adjusting " according to the formulation visual fatigue of Duke one II der, and Suzumura is defined as the syndrome of one group of subjective symptom that produces when working with eyesight with visual fatigue, and these symptoms comprise: blurred vision, headache, epiphora, shoulder is stiff and feel sick etc.Existing most ophthalmology scholars think that this disease is the symptom based on the conscious eye of patient, the syndrome that eye or the organic factor of whole body and spirit (psychology) factor are interweaved.Thereby also often be called as kopiopia syndrome, belong to the psychosomatic medicine category.
Cowberry is blueberry again, mainly grows in Europe, Russia, North America and Alps, and China has kind more than 90 approximately.Studies confirm that, the anthocyanidin that cowberry contains has stronger antioxidant action, long-term edible can assist to remove toxic chemical substance, free radical etc. in the retina, increasing the retina purpurine generates, improve Infravision, the help eyes adapt to the variation of strong and weak light, take for a long time to make eyesight lasting.Can also strengthen capillary, improve blood circulation, weaken hematoblastic viscosity, prevent the generation of blood clot, strengthen cardio cerebral function.
The fruit of Chinese wolfberry is the dry mature fruit of plant of Solanaceae lycium barbarum, has the effect of nourishing liver and kidney, benefiting shrewd head, moistening lung, is used for that consumptive disease is smart to be lost, soreness of waist and knee joint, and dizzy tinnitus, interior heat is quenched one's thirst, and the deficiency of blood is sallow, and blurred vision is not clear to wait disease.
Lycium barbarum is rich in carrotene, and carrotene can change vitamin A in human body.Vitamin A can promote the synthetic or regeneration of visual purple in the retina, keeps twenty-twenty vision.
Retina is a kind of special nerve fiber, and its content of taurine is high, and wherein the abundantest zone is the cellular regions that contains photoreceptor.The taurine that is in physiological level in retina has important function to the 26S Proteasome Structure and Function of keeping the visual cell.In vivo, in the retina under the taurine concentration general who has surrendered cause the photoreceptor structural damage, and unusual with serious visual function obstacle and electroretinogram.Behind the medicine that the supplementation of taurine or the obstruction taurine of stopping using absorb, it is normal that electroretinogram recovers.Have research to point out, fully taurine concentration reduces in the baby of parenteral alimentation, the children's blood plasma, some children occur together retinal structure, dysfunction.Improve after the supplementation of taurine.Discover that suitable supplementation of taurine and micronutrient can effectively improve low-light (level) occupational population night vision.Except that retina, crystalline lens, the blanket transparent body, optic nerve aixs cylinder also have relation with taurine.
Lecithin has anti-Oxidation of Fat and Oils effect, repairs the biomembrane of damage, keeps the formation of the stable of keratoderma moisture and inhibition horn cell lipofuscin, delays body aging.The cell membrane of human body cell mainly is made of lecithin.Human body replenishes lecithin can repair the cell membrane that is damaged, and increases the degree of unsaturation of the aliphatic acid of cell membrane, improves the function of film, makes its softening and rejuvenation.So just improved the power of regeneration of metabolic capability, self-healing ability and the body tissue of human body.
Summary of the invention
The object of the invention is to provide a kind of composition with asthenopia releasing function.
Another purpose of the present invention is to provide the method for the preparation of compositions with asthenopia releasing function.
The present invention is implemented by the following technical programs.
Health food of the present invention can be led by the raw material of following weight portion and make:
Bilberry fruit P.E 100-600 Fructus lycii P.E 200-600 taurine 100-500 soybean lecithin 4000-10000.The raw material of above-mentioned weight portion can be preferably: Bilberry fruit P.E 150 Fructus lycii P.Es 240 taurines 160 soybean lecithins 4500.
The present invention has the composition of asthenopia releasing function, also can add pharmaceutical necessities and make clinical acceptable different formulations such as tablet, capsule, granule, oral liquid, and the auxiliary material weight portion can be 500-16000.
Above-mentioned pharmaceutical necessities can comprise starch, lactose, dextrin, calcium sulfate, calcium carbonate, calcium monohydrogen phosphate, sodium carboxymethyl starch, xylitol, sweet mellow wine, sorbierite, microcrystalline cellulose, oil with hydrogenated soybean, olive oil, edible vegetable oil, polyethylene glycol wherein one or more.
The proanthocyanidin that the Bilberry fruit P.E extract that prior art makes contains has stronger antioxidant action, and alleviating asthenopia is had obvious effect.The Fructus lycii P.E that prior art makes is rich in beta carotene can be transformed into vitamin A in vivo.The two and taurine, lecithin compatibility use, and have lipotropism matter oxidation, repair the biomembrane of damage, promote the synthetic or regeneration of visual purple in the retina, keep twenty-twenty vision.The 26S Proteasome Structure and Function of keeping the visual cell had important function.The present composition uses with above-mentioned material combination, can Synergistic.
Present composition functional trial is the result show, has the effect of alleviating asthenopia.
The specific embodiment
The present invention is described further by embodiment.
Embodiment 1
Get Bilberry fruit P.E 100g, Fructus lycii P.E 200, taurine 100g, soybean lecithin 4000g, mix, add the 16000g dextrin, make granule according to a conventional method.
Embodiment 2
Get Bilberry fruit P.E 600g, Fructus lycii P.E 600, taurine 500g, soybean lecithin 10000g, mix, add the 8300g lactose, make granule according to a conventional method.
Embodiment 3
Get Bilberry fruit P.E 150g, Fructus lycii P.E 330, taurine 240g, soybean lecithin 5000g, mix, add 3000g starch, make tablet according to a conventional method.
Embodiment 4
Get Bilberry fruit P.E 200g, Fructus lycii P.E 400, taurine 340g, soybean lecithin 6000g, mix, add the 500g microcrystalline cellulose, make capsule according to a conventional method.
Embodiment 5
Get Bilberry fruit P.E 480g, Fructus lycii P.E 420, taurine 460g, soybean lecithin 6200g, mix, add the 3000g oil with hydrogenated soybean, stir, cross 200 order colloid mills, standby;
Get gelatin 200g, glycerine 118g, distilled water 230g makes rubber according to a conventional method, and content is packed into is pressed into capsule and pill, through cold air drying, the washing surface oil reservoir, drying, quality inspection, packing, promptly.
Embodiment 6
Get Bilberry fruit P.E 510g, Fructus lycii P.E 370, taurine 250g, soybean lecithin 4700g, mix, add 1000g calcium sulfate, make tablet according to a conventional method.
Embodiment 7
Get Bilberry fruit P.E 390g, Fructus lycii P.E 480, taurine 340g, soybean lecithin 5200g, mix, add the 1200g lactose, make capsule according to a conventional method.

Claims (5)

1, a kind of composition with asthenopia releasing function is characterized in that being made by the raw material of following weight portion:
Bilberry fruit P.E 100-600 Fructus lycii P.E 200-600 taurine 100-500 soybean lecithin 4000-10000.
2, the composition with asthenopia releasing function as claimed in claim 1 is characterized in that being made by the raw material of following weight portion:
Bilberry fruit P.E 150 Fructus lycii P.Es 240 taurines 160 soybean lecithins 4500.
3, the composition that has asthenopia releasing function according to claim 1 is characterized in that also can adding the auxiliary material of 500-1400 weight portion.
4,, it is characterized in that to add pharmaceutical necessities and make and comprise tablet, capsule, granule, soft capsule, any clinical acceptable forms of oral liquid as having the preparation of compositions method of asthenopia releasing function as described in claim 1 or 3.
5, as having the preparation of compositions method of efficacy of relieving visual fatigue as described in the claim 4, it is characterized in that pharmaceutical necessities can comprise starch, lactose, dextrin, calcium sulfate, calcium carbonate, calcium monohydrogen phosphate, sodium carboxymethyl starch, xylitol, sweet mellow wine, sorbierite, microcrystalline cellulose, oil with hydrogenated soybean, olive oil, edible vegetable oil, polyethylene glycol wherein one or more.
CNA2007101785610A 2007-11-30 2007-11-30 Composition capable of releasing asthenopia and preparation method thereof Pending CN101449820A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CNA2007101785610A CN101449820A (en) 2007-11-30 2007-11-30 Composition capable of releasing asthenopia and preparation method thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CNA2007101785610A CN101449820A (en) 2007-11-30 2007-11-30 Composition capable of releasing asthenopia and preparation method thereof

Publications (1)

Publication Number Publication Date
CN101449820A true CN101449820A (en) 2009-06-10

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CNA2007101785610A Pending CN101449820A (en) 2007-11-30 2007-11-30 Composition capable of releasing asthenopia and preparation method thereof

Country Status (1)

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CN (1) CN101449820A (en)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102150860A (en) * 2010-12-28 2011-08-17 北京同仁堂健康药业股份有限公司 Composition for easing visual fatigue and assisting in improving memory
CN103202472A (en) * 2013-04-25 2013-07-17 福建永生活力生物工程有限公司 Health food for relieving visual fatigues and preparation method of health food
CN105876408A (en) * 2014-09-10 2016-08-24 袁维理 Food with effects of protecting and improving eyesight
CN106666742A (en) * 2016-12-26 2017-05-17 北京信达方舟科技发展有限公司 Compound capsule containing grape seed extract and cowberry extract

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102150860A (en) * 2010-12-28 2011-08-17 北京同仁堂健康药业股份有限公司 Composition for easing visual fatigue and assisting in improving memory
CN102150860B (en) * 2010-12-28 2012-11-28 北京同仁堂健康药业股份有限公司 Composition for easing visual fatigue and assisting in improving memory
CN103202472A (en) * 2013-04-25 2013-07-17 福建永生活力生物工程有限公司 Health food for relieving visual fatigues and preparation method of health food
CN105876408A (en) * 2014-09-10 2016-08-24 袁维理 Food with effects of protecting and improving eyesight
CN106666742A (en) * 2016-12-26 2017-05-17 北京信达方舟科技发展有限公司 Compound capsule containing grape seed extract and cowberry extract

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Open date: 20090610