CN103446475A - Eye aging-resisting health product and preparation thereof - Google Patents
Eye aging-resisting health product and preparation thereof Download PDFInfo
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Abstract
The invention discloses an eye aging-resisting health product and a preparation of the eye aging-resisting health product. The eye aging-resisting health product comprises 10-50g of corn extract, 10-50g of blueberry extract, 1-5g of eyebright, 10-20g of cassia seed, 10-20g of Chinese wolfberry fruit, 10-30g of Chinese surname, 100-200mg of VE (Vitamin E), 100-300mg of VC (Vitamin C), 50-150mg of B1 and 50-150mg of VA (Vitamin A). Proper auxiliary materials are added in main materials for respectively preparing an effervescent tablet, a capsule, granules or a chewable tablet; the eye aging-resisting health product has the advantages of remarkable medicine effect and low price.
Description
Technical field
The invention belongs to field of health care products, be specifically related to old and feeble compositions and preparation and the application thereof of a kind of anti-eye.
Background technology
Along with improving constantly of people's living standard, people focus on the health care of daily life more, in face of China, low vision person more than 600 ten thousand are approximately arranged according to statistics, and the oblique amblyope of child approximately has 1,000 ten thousand; The adolescent myopia rate reaches 40%; University students's rate of myopia surpasses 70%, has a seemingly more and more difficult thing of healthy bright eyes, and the eyes that asthenopia causes in addition swell and ache, and itches, sheds tears, view is fuzzy is all perplexing people at any time, makes " window of soul " seem particularly important.
In the ophthalmology outpatient service, often can hear that some young people tell that eyes are dry and astringent, burning sensation or foreign body sensation are arranged, also have individually ophthalmic bloated, headache, the sore neck pain, detailed inspection finds that there is groups of people visual deterioration, conjunctival congestion, adjusting power descends, the cornea keratinization is seriously arranged, and lacrimal secretion reduces, and is diagnosed as asthenopia syndrome.
With this, how effectively to solve the daily effective nursing problem to eyes of people, " window of soul " that protect us become more and more people's demand, is also one of this current urgent problem in field simultaneously.
Summary of the invention
The advantages such as the technical problem to be solved in the present invention is that in the prior art scheme, health product or the medicine to asthenopia syndrome is few, the invention provides the old and feeble health product of a kind of anti-eye, has successful, cheap.
The technical solution used in the present invention: the present invention is the old and feeble health product of anti-eye, composed of the following components:
Corn extract: 10～50g, blue berry extract: 10～50g, Herba Euphrasiae Regelii: 1～5g, Semen Cassiae: 10～20g, Fructus Lycii: 10～20g, sweet Xun: 10～30g, VE:100～200mg, VC:100～300mg, B1:50～150mg and VA:50～150mg.
Further preferably, by following part, formed:
Corn extract: 38g, blue berry extract: 20g, Herba Euphrasiae Regelii: 3g, Semen Cassiae: 15g, Fructus Lycii: 18g, sweet Xun: 12g, VE:150mg, VC:100mg, B1:80mg and VA:120mg.
The preparation of the health product that the anti-eye of the present invention is old and feeble is effervescent tablet, capsule, granule or chewable tablet.
Wherein the preparation method of effervescent tablet is: above-mentioned formula mixed dissolution, in ethanol, then is added to disintegrating agent, filler, carbon dioxide source, fully mix, vacuum is granulated dry, sieves, then adds acid source, magnesium stearate to mix, and tabletting, obtain effervescent tablet.
Wherein the preparation method of capsule is: than fully mixing, add pregelatinized Starch by above-mentioned prescription, after mixing, use 8% binding agent, vacuum is granulated dry, and granulate, mix with the magnesium stearate of total amount 1.0%, encapsulated, obtains capsule.
Wherein the preparation method of granule is: in above-mentioned prescription ratio, wet method is fully mixed, vacuum drying, then be ground into fine powder, and add soluble starch and protein sugar to mix, with 50～90% ethanol granulations, through vacuum drying, granulate obtains granule.
Wherein the preparation method of chewable tablet is: than fully mixing, add adjuvant by above-mentioned prescription, sieve successively, and soft material processed, pelletize, vacuum drying, granulate, the gravity tabletting obtains chewable tablet.
The beneficial effect that the present invention reaches:
(1) corn extract: contain abundant lutein and cryptoxanthin, can reduce by 43% and suffer from the probability that old macula lutea sexually transmitted disease (STD) becomes, the antagonism eyes are aging; The blue berry extract is containing the abundant nutrients such as vitamin, protein and mineral, wherein the anthocyanin pigment of unique preciousness has the effect of maintenance well at the eyes to human body, it can relieving eye strain, improve people's vision, can directly accelerate the synthetic of retina, rhodopsin and regeneration, allow the eyes vigor brilliance that bursts forth; Herba Euphrasiae Regelii is called again Rhizoma et radix valerianae, main effective ingredient is flavone, it is a kind of very strong antioxidant, can effectively remove the oxygen-derived free radicals in body, as the full stage that anthocyanidin, anthocyanidin can the oil-control peroxide overflows, the ability of this prevention oxidation is more than ten times of vitamin E, this antioxidation can stop degeneration, the aging of cell, anti-eye strain improves the vision bright eyes and reproduces, and promotes vision and eye function, helps to subdue eye pouch and black eye; Semen Cassiae claims again " going back gb 1 ", Semen Cassiae contains multivitamin and abundant aminoacid, fat, carbohydrate etc., its health care is subject to people's attention day by day, there is the functions such as clearing away liver-fire, wind-damp dispelling, tonifying kidney and improving eyesight, prevent blurred vision, and Semen Cassiae is rich in vitamin A and zinc, can prevent and treat nyctalopia; The essential nutrition that Fructus Lycii contains the healthy eye such as the calcium such as abundant carotene, retinol1, B1, B2, C, ferrum, thus improving eyesight be good at, so be commonly called as " bright eye ".Blurring of vision and nyctalopia that ancient Chinese medicine doctor treatment deficiency of liver-blood, deficiency of kidney-YIN cause; Sweet Xun is Radix Dauci Sativae, contains abundant carotenoid, soluble sugar, starch, cellulose, multivitamin and multiple mineral element, have the title of " Radix Codonopsis Cardiophyllae ", also contains β-Hu Luo
Bu Su, can reach 50～170mg/kg, and beta-carotene is vitamin a source, forms vitamin A after hydrolysis, be the indispensable a kind of vitamin of human body, but enhancing development maintains normal vision, control nyctalopia, xerophthalmia; The VE(vitamin E) have free radical resisting: free radical is the reactive group extensively be present in various chemical reactions, and to human normal, physiological metabolism has important function; The VC(vitamin C) be the nutritional factors of intra-ocular lens, ascorbic intake deficiency, be to cause one of cataractous factor, and the patient should many vitimin supplement C; The B1(vitamin B1) can prevent the generation of Wernicke syndrome; The VA:(vitamin A) can maintain the normal vision function, the photoreceptor of eye is staff cell and the cone cell in retina.These two kinds of cells all have photopigment, feel the rhodopsin of the low light level and the iodopsin of sense high light.Rhodopsin and iodopsin are all to consist of opsin and retinal.Rhodopsin is after rayed, and the 11-cis retinal isomery becomes trans-retinene, and separates and eclipsed with the opsin, and this process claims " bleaching ".If enter dark place, because the insensitive rhodopsin of the low light level is disappeared, therefore can not see thing; Retinal after separation is reduced to all-trans-retinal, further changes trans retinyl ester (or tautomerizing to cis) into and is stored in pigment epithelium.Retinyl ester hydrolytic enzyme in retina, change retinyl ester into trans retinol, through oxidation and isomerization, forms 11-cis retinal.Again be combined into rhodopsin with albumen again, recover the sensitivity to the low light level, thereby can see thing in the dark place of certain illumination, this process claims secretly; The retinol and retinol binding protein (RBP) combination that by liver, are discharged are combined with prealbumin in blood plasma again, are transported to retina, participate in amphiblestroid photochemical reaction, if the vitamin A abundance, the regeneration of rhodopsin is fast and complete, therefore dark adaptation is short recovery time; If hypovitaminosis A, rhodopsin regeneration is slow and incomplete, therefore dark adaptation extends recovery time, when serious, can produce nyctalopia.
(2) drug effect effect of the present invention can illustrate by following pharmacological evaluation.Pharmacological evaluation:
One, on the impact of rabbit eyes Bulbar conjunctiva microcirculation.
(1) experiment material:
1, animal: the rabbit male and female have concurrently, body weight 2.0kg～3.5kg.
2, medicine: the medicament of the embodiment of the present invention 1～5 preparation.Medicine is at the configuration of use for laboratory distilled water, gastric infusion.
(2) experimental technique:
Adopt rabbit eyes conjunctiva blood capillary fluorimetry.50 of rabbit, male and female half and half, body weight 2.0kg～3.5kg, be divided into 5 groups at random, 10 every group.The matched group gavage is with the normal saline of volume; The present invention is gavage embodiment 1～4 administration 0.5g/kg respectively; Successive administration 7d, every day 1 time, each 10ml/kg, 1h after the last administration, the fluorescein sodium normal saline solution 1ml/kg(of ear vein injection 10% is equivalent to 100mg/kg), record the time that fluorescence appears in rabbit conjunctival.Experimental result is shown in Table 1:
The impact of table 1 on the rabbit eyes Bulbar conjunctiva microcirculation
| Grouping | Animal (only) | Dosage (g/kg) | The fluorescence time of occurrence |
| Matched group | 10 | / | 12.95±2.59 |
| Embodiment 1 | 10 | 0.5 | 10.05±2.34 |
| Embodiment 2 | 10 | 0.5 | 9.56±3.16 |
| Embodiment 3 | 10 | 0.5 | 9.78±2.79 |
| Embodiment 4 | 10 | 0.5 | 9.98±2.54 |
| Embodiment 5 | 10 | 0.5 | 9.36±2.48 |
Experimental result shows: the present invention has obvious acceleration rabbit eyes Bulbar conjunctiva microcirculation blood flow, promotes the microcirculation of eye, improves supply of blood flow.
Two, on the impact of rat galactose cataract model.
(1) experiment material:
1, animal: the SD rat, male and female have concurrently, body weight 250g～350g.
2, medicine: the medicament of the embodiment of the present invention 1～5 preparation.Medicine is at the configuration of use for laboratory distilled water, gastric infusion.
(2) experimental technique:
The SD rat, at first make eye examination, selects 60 of the normal persons of eyes, male and female half and half, and body weight 250g～350g, 6 groups of random assortment, the matched group gavage is with the normal saline of volume; The present invention is gavage embodiment 1～4 administration 0.5g/kg respectively; Successive administration 5d, every day 1 time, administration volume 1.5ml/100g, after 5d, each group, all to D-galactose (half-and-half is mixed in feedstuff), continues gastric infusion and normal saline, until the core muddiness occurs simultaneously.Every 3d eyes drip mydriatic 1 time, and with the eye examination with slitlamp microscope, record enters the time of core muddiness, and experimental result is shown in Table 2:
The impact of table 2 on rat galactose cataract model
| Grouping | Animal (only) | Dosage (g/kg) | Muddy formation time |
| Matched group | 10 | / | 20.95±6.59 |
| Embodiment 1 | 10 | 0.5 | 28.42±7.56 |
| Embodiment 2 | 10 | 0.5 | 27.24±8.23 |
| Embodiment 3 | 10 | 0.5 | 29.43±7.49 |
| Embodiment 4 | 10 | 0.5 | 28.98±8.71 |
| Embodiment 5 | 10 | 0.5 | 29.15±7.57 |
Experimental result shows: health product of the present invention are stronger to the inhibitory action of the cataractous formation of rat galactose.
Three, on the impact of glaucoma retina optic ganglion cell apoptosis.
(1) experiment material:
1, animal: the rabbit male and female have concurrently, body weight 2.0kg～3.5kg.
2, medicine: the medicament of the embodiment of the present invention 1～5 preparation.Medicine is at the configuration of use for laboratory distilled water, gastric infusion.
(2) experimental technique:
50 of rabbit, male and female half and half, body weight 2.0kg～3.5kg, be divided into 6 groups at random, 10 every group.After preparing fixedly red cell suspension, after every rabbit left eye anterior chamber extracts the 0.2ml aqueous humor out, the fixedly red cell suspension of injection 0.2ml, cause glaucoma model.Every daily Chloramphenicol Eye Drop antiinflammatory.Experiment starts, and the matched group gavage is with the normal saline of volume; The present invention is gavage embodiment 1～4 administration 0.5g/kg respectively; Successive administration 36d, every day 1 time, each 10ml/kg, put to death rabbit, win fast eyeball, at angle, the Gong Yuan place cuts off cornea, iris and crystalline lens, after getting as much as possible clean vitreous body, wall of eyeball is fixed in to 4% paraformaldehyde at least after 24h, more than flowing water rinses 15h, with 80% ethanol, fix again, make the TUNEL dye marker, detect apoptosis, om observation, apoptosis cell in counting cells, experimental result is shown in Table 2:
The impact of table 3 on glaucoma retina optic ganglion cell apoptosis
| Grouping | Animal (only) | Dosage (g/kg) | Muddy formation time |
| Matched group | 10 | / | 6.95±2.59 |
| Embodiment 1 | 10 | 0.5 | 4.95±1.52 |
| Embodiment 2 | 10 | 0.5 | 5.21±2.21 |
| Embodiment 3 | 10 | 0.5 | 5.14±1.95 |
| Embodiment 4 | 10 | 0.5 | 5.24±1.86 |
| Embodiment 5 | 10 | 0.5 | 5.09±2.57 |
Experimental result shows: health product of the present invention are strong to the protective effect of glaucoma retina optic ganglion cell apoptosis.
The specific embodiment:
Embodiment 1
The old and feeble health product of the anti-eye of the present invention, composed of the following components:
Corn extract: 38g, blue berry extract: 20g, Herba Euphrasiae Regelii: 3g, Semen Cassiae: 15g, Fructus Lycii: 18g, sweet Xun: 12g, VE:150mg, VC:100mg, B1:80mg and VA:120mg.Above-mentioned formula mixed dissolution, in ethanol, then is added to disintegrating agent, filler, carbon dioxide source, fully mix, vacuum is granulated dry, sieves, then adds acid source, mixes, and tabletting, obtain effervescent tablet.
Embodiment 2
The old and feeble health product of anti-eye of the present invention, composed of the following components:
Corn extract: 38g, blue berry extract: 20g, Herba Euphrasiae Regelii: 3g, Semen Cassiae: 15g, Fructus Lycii: 18g, sweet Xun: 12g, VE:150mg, VC:100mg, B1:80mg and VA:120mg.Than fully mixing, add pregelatinized Starch by above-mentioned prescription, after mixing, by 8% binding agent vacuum granulation, drying, granulate, mix with the magnesium stearate of total amount 1.0%, encapsulated, obtains capsule.
Embodiment 3
The old and feeble health product of a kind of anti-eye of the present invention, composed of the following components:
Corn extract: 38g, blue berry extract: 20g, Herba Euphrasiae Regelii: 3g, Semen Cassiae: 15g, Fructus Lycii: 18g, sweet Xun: 12g, VE:150mg, VC:100mg, B1:80mg and VA:120mg.In the wet mixing of above-mentioned prescription ratio, fully mix, vacuum drying, then be ground into fine powder, and add soluble starch and protein sugar to mix, with 90% ethanol granulation, through vacuum drying, granulate obtains granule.
Embodiment 4
The old and feeble health product of anti-eye of the present invention is characterized in that: composed of the following components:
Corn extract: 50g, blue berry extract: 50g, Herba Euphrasiae Regelii: 5g, Semen Cassiae: 15g, Fructus Lycii: 20g, sweet Xun: 10g, VE:200mg, VC:300mg, B1:150mg and VA:150mg.Above-mentioned formula mixed dissolution, in ethanol, then is added to disintegrating agent, filler, carbon dioxide source, fully mix, vacuum is granulated dry, sieves, then adds acid source, magnesium stearate to mix, and tabletting, obtain effervescent tablet.
Embodiment 5
The old and feeble health product of anti-eye of the present invention, composed of the following components:
Corn extract: 10g, blue berry extract: 10g, Herba Euphrasiae Regelii: 3g, Semen Cassiae: 10g, Fructus Lycii: 10g, sweet Xun: 10g, VE:100mg, VC:100mg, B1:50mg and VA:50mg.
Than fully mixing, add pregelatinized Starch by above-mentioned prescription, after mixing, granulate with 8% binding agent, vacuum drying, granulate, mix with the magnesium stearate of total amount 1.0%, encapsulated, obtains capsule.
Embodiment 6
The old and feeble health product of the anti-eye of the present invention, composed of the following components:
Corn extract: 38g, blue berry extract: 20g, Herba Euphrasiae Regelii: 3g, Semen Cassiae: 15g, Fructus Lycii: 18g, sweet Xun: 12g, VE:150mg, VC:100mg, B1:80mg and VA:120mg.Fully mix in above-mentioned prescription ratio, add adjuvant, sieve successively, soft material processed, pelletize, vacuum drying, granulate, the gravity tabletting obtains chewable tablet.
Claims (7)
1. health product that anti-eye is old and feeble is characterized in that: composed of the following components:
Corn extract: 10～50g, blue berry extract: 10～50g, Herba Euphrasiae Regelii: 1～5g, Semen Cassiae: 10～20g, Fructus Lycii: 10～20g, sweet Xun: 10～30g, VE:100～200mg, VC:100～300mg, B1:50～150mg and VA:50～150mg.
2. old and feeble health product of anti-eye according to claim 1 is characterized in that: following part, consist of:
Corn extract: 38g, blue berry extract: 20g, Herba Euphrasiae Regelii: 3g, Semen Cassiae: 15g, Fructus Lycii: 18g, sweet Xun: 12g, VE:150mg, VC:100mg, B1:80mg and VA:120mg.
3. the preparation of the health product of anti-eye aging according to claim 1 is effervescent tablet, capsule, granule or chewable tablet.
4. the preparation of the old and feeble health product of anti-eye according to claim 3, it is characterized in that: the preparation method of effervescent tablet is: by above-mentioned formula mixed dissolution in ethanol, add again disintegrating agent, filler, carbon dioxide source, fully mix, vacuum drying, sieve, add again acid source, mix, tabletting, obtain effervescent tablet.
5. the preparation of the old and feeble health product of anti-eye according to claim 3, it is characterized in that: the preparation method of capsule is: by above-mentioned prescription, than abundant, mix, add pregelatinized Starch, after mixing, use 8% binding agent, vacuum drying, granulate, with the magnesium stearate of total amount 1.0%, mix, encapsulated, obtain capsule.
6. the preparation of the old and feeble health product of anti-eye according to claim 3, it is characterized in that: the preparation method of granule is: by above-mentioned prescription than fully mixing, vacuum drying, then powder
Be broken into fine powder, add soluble starch and protein sugar to mix, with 50%～90% ethanol granulation, through vacuum drying, granulate obtains granule.
7. the preparation of the old and feeble health product of anti-eye according to claim 3, it is characterized in that: the preparation method of chewable tablet is: by above-mentioned prescription, than fully mixing, add adjuvant, sieve successively, soft material processed, pelletize, vacuum drying, granulate, tabletting obtains chewable tablet.
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105360855A (en) * | 2015-11-13 | 2016-03-02 | 南京中医药大学 | Beverage for resisting eye fatigue and preparation method thereof |
| CN105495589A (en) * | 2015-12-16 | 2016-04-20 | 李新福 | Chewable tablets for eyesight protection and preparing method thereof |
| CN106418512A (en) * | 2016-10-25 | 2017-02-22 | 吉林大学 | Multi-flavor corn effervescent tablets and preparation method |
| CN108157575A (en) * | 2018-01-03 | 2018-06-15 | 江苏海王健康生物科技有限公司 | A kind of pressed candy for alleviating visual fatigue and preparation method and application |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101229287A (en) * | 2007-11-02 | 2008-07-30 | 郭富凤 | Polynary lycopene preventing and treating eye disease capsule and preparing method thereof |
-
2013
- 2013-08-08 CN CN201310344517.8A patent/CN103446475B/en active Active
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101229287A (en) * | 2007-11-02 | 2008-07-30 | 郭富凤 | Polynary lycopene preventing and treating eye disease capsule and preparing method thereof |
Non-Patent Citations (1)
| Title |
|---|
| 许津: "中老年保眼有道", 《药物与人》, 30 November 2007 (2007-11-30), pages 42 - 43 * |
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105360855A (en) * | 2015-11-13 | 2016-03-02 | 南京中医药大学 | Beverage for resisting eye fatigue and preparation method thereof |
| CN105360855B (en) * | 2015-11-13 | 2018-01-19 | 南京中医药大学 | A kind of beverage with anti-kopiopia and preparation method thereof |
| CN105495589A (en) * | 2015-12-16 | 2016-04-20 | 李新福 | Chewable tablets for eyesight protection and preparing method thereof |
| CN105495589B (en) * | 2015-12-16 | 2018-06-26 | 深圳市东盛堂美妆科技有限公司 | Protect chewable tablets of eyesight and preparation method thereof |
| CN106418512A (en) * | 2016-10-25 | 2017-02-22 | 吉林大学 | Multi-flavor corn effervescent tablets and preparation method |
| CN108157575A (en) * | 2018-01-03 | 2018-06-15 | 江苏海王健康生物科技有限公司 | A kind of pressed candy for alleviating visual fatigue and preparation method and application |
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| CN103446475B (en) | 2015-10-28 |
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