CN107213271A - One kind alleviates asthenopia tablet and preparation method thereof - Google Patents
One kind alleviates asthenopia tablet and preparation method thereof Download PDFInfo
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- CN107213271A CN107213271A CN201710395968.2A CN201710395968A CN107213271A CN 107213271 A CN107213271 A CN 107213271A CN 201710395968 A CN201710395968 A CN 201710395968A CN 107213271 A CN107213271 A CN 107213271A
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- asthenopia
- seed extract
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/482—Cassia, e.g. golden shower tree
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
- A61K31/23—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/02—Algae
- A61K36/05—Chlorophycota or chlorophyta (green algae), e.g. Chlorella
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/11—Pteridophyta or Filicophyta (ferns)
- A61K36/12—Filicopsida or Pteridopsida
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/87—Vitaceae or Ampelidaceae (Vine or Grape family), e.g. wine grapes, muscadine or peppervine
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2068—Compounds of unknown constitution, e.g. material from plants or animals
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Abstract
Alleviate asthenopia tablet the invention discloses one kind.The alleviation asthenopia tablet includes by mass percentage:Cassia seed extract 5 30%, lycium ruthenicum 5 20%, lutein ester 1 12%, salt algae 1 10%, blackcurrant extract 5 20%, grape seed extract 5 20%, auxiliary material surplus.The alleviation asthenopia tablet that the present invention is provided can effectively protect eyesight, alleviate visual fatigue, prevent senile macular degeneration.Macular degeneration is improved by lutein ester, visual fatigue, livid ring around eye are alleviated by adding anthocyanin, promotes rhodopsin to synthesize by adding bata-carotene, many-side protection eyesight.The present invention also provides a kind of preparation method for alleviating asthenopia tablet.
Description
Technical field
Alleviate asthenopia tablet, more particularly to a kind of cassia seed extract, lycium ruthenicum powder, leaf Huang the present invention relates to one kind
Plain ester, salt algae, alleviation asthenopia tablet of blackcurrant extract and grape seed extract and preparation method thereof.
Background technology
Retina is the vital tissue organ that human body produces vision, and light only has the normally functioning retina of arrival, ability
Visual pattern is formed, excessively weak or too strong light can all influence the formation of normal vision image.If the intensity of light, illumination
Time withstands forces more than retina, it will cause the damage of retina.Macular area is that retina Posterior pole is pigmentosa in the presence of one
Region, is in yellow because of lutein containing high concentration, therefore is referred to as " macula lutea ".Macular area has unique tissue cellularity, bears
Blame most sharp vision, colour vision and shape and feel function, retinal cones cell is distributed in this area intensive, and contains abundant leaf
Flavine and luteole are macular pigment, and these pigments and macular function and anti-oxidative damage are closely related.
In the last few years, ascendant trend, especially acquired environment factor year by year was presented in China's myopia population and ophthalmology illness, than
As excess eye-using, reading distance are too near, use computer cell phone for a long time.Low vision can cause eyes often dry and astringent and fatigue,
Have a strong impact on study, the quality of live and work.Myopia through commonly using eye may occur in which that eyelid is heavy, there is foreign body sensation, and ophthalmodynia is bent
Beche-de-mer without spike is poor, excessively not good with eye or general body state.Western medicine on the market can bring certain toxic side effect, the eye drip of fatigue-relieving
Liquid is also to cure the symptoms, not the disease.It therefore one kind is provided can improve macular degeneration, alleviate visual fatigue, livid ring around eye, promotion and regard
The alleviation asthenopia nutriment of rhodopsin synthesis seems and is extremely necessary.
The content of the invention
The present invention provides a kind of containing cassia seed extract, lycium ruthenicum powder, lutein ester, salt algae, blackcurrant extract, grape
The alleviation asthenopia tablet of seed extract, for improving macular degeneration, alleviating visual fatigue, livid ring around eye, promotion visual purple
Red matter synthesis.
The purpose of the present invention is achieved through the following technical solutions.
One kind alleviates asthenopia tablet, and its component includes cassia seed extract, lycium ruthenicum powder, lutein ester, salt algae, black
Gallon extract, grape seed extract and auxiliary material.
In alleviation asthenopia tablet provided in an embodiment of the present invention, mass percent is as follows shared by each component:
It is provided in an embodiment of the present invention alleviation asthenopia tablet in, the auxiliary material include microcrystalline cellulose, xylitol,
Isomaltoketose, Aspartame, inulin, sucrose, lactose, rice meal, resistant dextrin, cyclodextrine, silica, magnesium stearate
One or more.
Further, it is further characterized in that, a kind of preparation method of improvement sleeping tablets as described above, including following step
Suddenly;
S1, by recipe requirements measure each raw material, specifically include cassia seed extract, lycium ruthenicum powder, lutein ester, salt algae,
Blackcurrant extract, grape seed extract and auxiliary material;
S2, each raw material obtained in step sl is well mixed;
S3, by the well mixed raw material prepared in step s 2 by tablet press machine carry out tabletting, so as to obtain shape
Into solid tablet.
The present invention enters pine torch extract, lycium ruthenicum powder, lutein ester, salt algae, blackcurrant extract, grape seed extract
Row coordinates prescription, can effectively play the effect of various composition, and is conducive to utilizing the synergy between each composition, effectively changes
Kind macular degeneration, alleviation visual fatigue, livid ring around eye.This formula major technique effect is:
It can be promoted by the anthocyanidin and the synergy of beta carotene in grape seed extract and blackcurrant extract
The palingenesis of rhodopsin, increases visual acuity, accelerates the adaptability to dark surrounds.Further, in matrimony vine
Damaging action of the LBP-X energy antagonism AGEP to nerve cell.And by the cassia seed element in cassia seed, certainly
Pine torch lactone, Chrysophanol, Physcion substantially increase the protective effect to retinal neuronal cell, suppress advanced glycosylation endproduct production
The generation of thing and its component, the time of delay AGEP accumulation.LBP-X energy antagonism glycosylation in lycium ruthenicum powder
End-product has protective effect to the damaging action of nerve cell to retinal neuronal cell.Lutein ester can be efficient simultaneously
Free lutein is discharged, promotes the recovery of the retina of damage while retinal neuronal cell is protected.So, pass through each group
Point effectively act synergistically, it is possible to reduce because light exposes the retinal damage caused, the people of raising is to photopic vision, scotopia and right
The sensitivity level of short wavelength light, increases macula retinae density.
Embodiment
With reference to specific embodiment, the present invention is expanded on further.These embodiments are interpreted as being merely to illustrate this hair
It is bright rather than limit the scope of the invention.After the content of the invention recorded has been read, those skilled in the art can
To be made various changes or modifications to the present invention, these equivalence changes and modification equally fall into the model that the claims in the present invention are limited
Enclose.In the present invention, refered in particular to as non-, all amounts, part, percentage is weight, and all raw material can be purchased from market
.
Contain cassia seed extract, lycium ruthenicum powder, lutein ester, salt algae, blackcurrant extract, Portugal the invention provides one kind
The production method of the alleviation asthenopia tablet of grape seed extract, it will be appreciated, of course, that the tablet is solid tablet.It is described
The production method for alleviating asthenopia tablet comprises the following steps;
S1, by recipe requirements measure each raw material, specifically include cassia seed extract, lycium ruthenicum powder, lutein ester, salt algae,
Blackcurrant extract, grape seed extract and auxiliary material
S2, each raw material obtained in step sl is well mixed;
S3, the well mixed tablet press machine prepared in step s 2 is subjected to tabletting, so as to prepare to form solid piece
Agent.
It is prepared into after fixed tablet and can be not limited solely to specific in embodiment directly according to certain amount bag distribution packaging
Quantity, so as to form final product.In the present invention, the quality per tablet is 0.4~2g, the tablet quality of every bag of product
For 5g.Certainly, the tablet quality of every bag of product can also be other quality, and the present invention is not limited this.
The invention will be further described by the following examples.
Embodiment 1
The alleviation asthenopia tablet provided in the present embodiment includes cassia seed extract, lycium ruthenicum powder, lutein ester, salt
Algae, blackcurrant extract, grape seed extract, microcrystalline cellulose, resistant dextrin, lactose, sucrose, silica and stearic acid
Magnesium, wherein above-mentioned raw materials are prepared as following.
Each component content is respectively in per 100g:
Then the raw material of above-mentioned quality proportioning is well mixed with batch mixer, direct tablet compressing, or 50 pieces/bottle packing.
Embodiment 2
The alleviation asthenopia tablet provided in the present embodiment includes cassia seed extract, lycium ruthenicum powder, lutein ester, salt
Algae, blackcurrant extract, grape seed extract, microcrystalline cellulose, xylitol, lactose, silica and magnesium stearate, wherein on
Raw material is stated to be prepared by following.
Each component content is respectively in per 100g:
Then the raw material of above-mentioned quality proportioning is well mixed with batch mixer, direct tablet compressing, or 60 pieces/bottle packing.
Embodiment 3
The improvement sleeping tablets provided in the present embodiment include cassia seed extract, lycium ruthenicum powder, lutein ester, salt algae,
Blackcurrant extract, grape seed extract, microcrystalline cellulose, isomaltoketose, rice meal, cyclodextrine, lactose, titanium dioxide
Silicon, wherein above-mentioned raw materials are prepared as following.
Table 3:Each component content is respectively in per 100g:
Then the raw material of above-mentioned quality proportioning is well mixed with batch mixer, direct tablet compressing, or 70 pieces/bottle packing.
Embodiment 4
The improvement sleeping tablets provided in the present embodiment include cassia seed extract, lycium ruthenicum powder, lutein ester, salt algae,
Blackcurrant extract, grape seed extract, microcrystalline cellulose, Aspartame, inulin, rice meal, cyclodextrine, sucrose, dioxy
SiClx, wherein above-mentioned raw materials are prepared as following.
Table 4:Each component content is respectively in per 100g:
Then the raw material of above-mentioned quality proportioning is well mixed with batch mixer, direct tablet compressing.
Embodiment 5
The improvement sleeping tablets provided in the present embodiment include cassia seed extract, lycium ruthenicum powder, lutein ester, salt algae,
Blackcurrant extract, grape seed extract, microcrystalline cellulose, Aspartame, inulin, rice meal, cyclodextrine, sucrose, dioxy
SiClx, wherein above-mentioned raw materials are prepared as following.
Table 5:Each component content is respectively in per 100g:
Embodiment 6
The improvement sleeping tablets provided in the present embodiment include cassia seed extract, lycium ruthenicum powder, lutein ester, salt algae,
Blackcurrant extract, grape seed extract, microcrystalline cellulose, Aspartame, inulin, rice meal, cyclodextrine, sucrose, dioxy
SiClx, wherein above-mentioned raw materials are prepared as following.
Table 6:Each component content is respectively in per 100g:
It is obvious to a person skilled in the art that the invention is not restricted to the details of above-mentioned one exemplary embodiment, Er Qie
In the case of without departing substantially from spirit or essential attributes of the invention, the present invention can be realized in other specific forms.Therefore, no matter
From the point of view of which point, embodiment all should be regarded as exemplary, and be nonrestrictive, the scope of the present invention is by appended power
Profit is required rather than described above is limited, it is intended that all in the implication and scope of the equivalency of claim by falling
Change is included in the present invention.
Moreover, it will be appreciated that although the present specification is described in terms of embodiments, not each embodiment is only wrapped
Containing an independent technical scheme, this narrating mode of specification is only that for clarity, those skilled in the art should
Using specification as an entirety, the technical solutions in the various embodiments may also be suitably combined, forms those skilled in the art
It may be appreciated other embodiment.
Claims (4)
1. one kind alleviates asthenopia tablet, it is characterised in that its component includes cassia seed extract, lycium ruthenicum powder, lutein
Ester, salt algae, blackcurrant extract and grape seed extract.
2. alleviate asthenopia tablet as claimed in claim 1, it is characterised in that also including auxiliary material, the auxiliary material includes:It is micro-
Crystalline cellulose, xylitol, isomaltoketose, Aspartame, inulin, Sucralose, lactose, sucrose, rice meal, resistant dextrin,
Cyclodextrine, silica, the one or more of magnesium stearate.
3. alleviation asthenopia tablet according to claim 2, it is characterised in that:Mass percent shared by each component is such as
Under:
4. a kind of preparation method according to claim 1 for alleviating asthenopia tablet, comprises the following steps:
S1, by recipe requirements measure each raw material, specifically include cassia seed extract, lycium ruthenicum powder, lutein ester, salt algae, it is black plus
Logical sequence extract, grape seed extract, auxiliary material;
S2, each raw material obtained in step sl is well mixed;
S3, by the well mixed raw material prepared in step s 2 by tablet press machine carry out tabletting, so as to obtain solid piece
Agent.
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Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN108157568A (en) * | 2017-12-29 | 2018-06-15 | 广东粤微食用菌技术有限公司 | A kind of Combined candy for alleviating visual fatigue and its preparation method and application |
CN108208835A (en) * | 2018-02-02 | 2018-06-29 | 李万才 | A kind of black, red matrimony vine compound eyeshield oral liquid and preparation method thereof |
CN108524667A (en) * | 2018-05-23 | 2018-09-14 | 南京中生生物科技有限公司 | It is a kind of that there is the lutein ester composition and preparation method thereof for alleviating visual fatigue effect |
CN109123311A (en) * | 2018-10-19 | 2019-01-04 | 贵阳高新瑞得科技开发有限公司 | A kind of effervescent tablet health food for alleviating visual fatigue |
CN111214640A (en) * | 2020-04-01 | 2020-06-02 | 梭医生物科技(上海)股份有限公司 | Leaf yellow Chinese wolfberry tablet capable of rapidly improving eyesight and preparation method thereof |
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CN101433638A (en) * | 2007-11-16 | 2009-05-20 | 北京因科瑞斯医药科技有限公司 | Composition with function for alleviating eyestrain and preparation method thereof |
CN104161260A (en) * | 2014-07-23 | 2014-11-26 | 北京中泰天和科技有限公司 | Composition used for relieving asthenopia and preparation method thereof |
CN105687483A (en) * | 2016-03-09 | 2016-06-22 | 宁波君瑞生物科技有限公司 | Granular preparation with function of improving eyesight |
-
2017
- 2017-05-31 CN CN201710395968.2A patent/CN107213271A/en active Pending
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
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CN101433638A (en) * | 2007-11-16 | 2009-05-20 | 北京因科瑞斯医药科技有限公司 | Composition with function for alleviating eyestrain and preparation method thereof |
CN104161260A (en) * | 2014-07-23 | 2014-11-26 | 北京中泰天和科技有限公司 | Composition used for relieving asthenopia and preparation method thereof |
CN105687483A (en) * | 2016-03-09 | 2016-06-22 | 宁波君瑞生物科技有限公司 | Granular preparation with function of improving eyesight |
Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN108157568A (en) * | 2017-12-29 | 2018-06-15 | 广东粤微食用菌技术有限公司 | A kind of Combined candy for alleviating visual fatigue and its preparation method and application |
CN108208835A (en) * | 2018-02-02 | 2018-06-29 | 李万才 | A kind of black, red matrimony vine compound eyeshield oral liquid and preparation method thereof |
CN108524667A (en) * | 2018-05-23 | 2018-09-14 | 南京中生生物科技有限公司 | It is a kind of that there is the lutein ester composition and preparation method thereof for alleviating visual fatigue effect |
CN109123311A (en) * | 2018-10-19 | 2019-01-04 | 贵阳高新瑞得科技开发有限公司 | A kind of effervescent tablet health food for alleviating visual fatigue |
CN111214640A (en) * | 2020-04-01 | 2020-06-02 | 梭医生物科技(上海)股份有限公司 | Leaf yellow Chinese wolfberry tablet capable of rapidly improving eyesight and preparation method thereof |
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Address after: 224100 No. 51 Nanxiang Road, Dafeng Economic Development Zone, Yancheng City, Jiangsu Province Applicant after: Jiangsu Bacterial Key Life Science and Technology Development Co., Ltd. Address before: 224100 No. 51 Nanxiang Road, Dafeng Economic Development Zone, Yancheng City, Jiangsu Province Applicant before: Jiangsu grain health life science & Technology Development Co Ltd |
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