CN108524667A - It is a kind of that there is the lutein ester composition and preparation method thereof for alleviating visual fatigue effect - Google Patents
It is a kind of that there is the lutein ester composition and preparation method thereof for alleviating visual fatigue effect Download PDFInfo
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- CN108524667A CN108524667A CN201810506149.5A CN201810506149A CN108524667A CN 108524667 A CN108524667 A CN 108524667A CN 201810506149 A CN201810506149 A CN 201810506149A CN 108524667 A CN108524667 A CN 108524667A
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- blueberry
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- SBNFWQZLDJGRLK-UHFFFAOYSA-N phenothrin Chemical compound CC1(C)C(C=C(C)C)C1C(=O)OCC1=CC=CC(OC=2C=CC=CC=2)=C1 SBNFWQZLDJGRLK-UHFFFAOYSA-N 0.000 description 1
- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 description 1
- 239000010452 phosphate Substances 0.000 description 1
- PKUBGLYEOAJPEG-UHFFFAOYSA-N physcion Natural products C1=C(C)C=C2C(=O)C3=CC(C)=CC(O)=C3C(=O)C2=C1O PKUBGLYEOAJPEG-UHFFFAOYSA-N 0.000 description 1
- 231100000614 poison Toxicity 0.000 description 1
- 230000003389 potentiating effect Effects 0.000 description 1
- 208000008128 pulmonary tuberculosis Diseases 0.000 description 1
- 230000009467 reduction Effects 0.000 description 1
- 230000008439 repair process Effects 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 230000002207 retinal effect Effects 0.000 description 1
- 230000005070 ripening Effects 0.000 description 1
- 238000005070 sampling Methods 0.000 description 1
- 230000037394 skin elasticity Effects 0.000 description 1
- 210000002784 stomach Anatomy 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 239000013589 supplement Substances 0.000 description 1
- 235000019605 sweet taste sensations Nutrition 0.000 description 1
- 239000003826 tablet Substances 0.000 description 1
- 235000012976 tarts Nutrition 0.000 description 1
- 239000003440 toxic substance Substances 0.000 description 1
- 230000010415 tropism Effects 0.000 description 1
- 231100000397 ulcer Toxicity 0.000 description 1
- 235000013311 vegetables Nutrition 0.000 description 1
- 229940088594 vitamin Drugs 0.000 description 1
- 229930003231 vitamin Natural products 0.000 description 1
- 235000013343 vitamin Nutrition 0.000 description 1
- 239000011782 vitamin Substances 0.000 description 1
- NCYCYZXNIZJOKI-UHFFFAOYSA-N vitamin A aldehyde Natural products O=CC=C(C)C=CC=C(C)C=CC1=C(C)CCCC1(C)C NCYCYZXNIZJOKI-UHFFFAOYSA-N 0.000 description 1
- 235000019165 vitamin E Nutrition 0.000 description 1
- 229940046009 vitamin E Drugs 0.000 description 1
- 239000011709 vitamin E Substances 0.000 description 1
- 150000003722 vitamin derivatives Chemical class 0.000 description 1
- 230000037303 wrinkles Effects 0.000 description 1
- 208000005494 xerophthalmia Diseases 0.000 description 1
- 239000011701 zinc Substances 0.000 description 1
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Classifications
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- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
- A61K31/23—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms
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- A61K35/56—Materials from animals other than mammals
- A61K35/618—Molluscs, e.g. fresh-water molluscs, oysters, clams, squids, octopus, cuttlefish, snails or slugs
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Abstract
It is a kind of that there is the lutein ester composition and preparation for alleviating visual fatigue effect, it is related to field of health care products, it is using lutein ester as main component, quantitative compatibility is carried out with Chinese medicines with improving eyesight effect such as black fruit fructus lycii, blueberry, Cassia occidentalis, the shell of seaear, mulberry leaf and honeysuckles, makes to generate apparent synergistic function between each raw material the effective elements of the medicine.Can be effectively relieved as caused by asthenopia eye is dry, eye is puckery, the sour swollen, blurred vision of eye even visual impairment the problems such as.The composition and preparation smell, good taste, edible safety, it is without any side effects.A kind of above-mentioned preparation method with the composition for alleviating visual fatigue effect, black fruit fructus lycii, blueberry, Cassia occidentalis, the shell of seaear, mulberry leaf and honeysuckle are respectively dried, are crushed into powder, then is mixed with Lutein ester microcapsule powder, bata-carotene.The preparation method is easy to operate, can preferably coordinate the sensory difference between each raw material, and preferably retains the active ingredient in raw material.
Description
Technical field
The present invention relates to field of health care products, in particular to a kind of lutein ester group for having and alleviating visual fatigue effect
Close object and preparation method thereof.
Background technology
Asthenopia is a kind of ophthalmology common disease, and the eye caused by it is dry, eye is puckery, under the sour swollen, blurred vision of eye even eyesight
Drop, directly affects the work and life of people.Asthenopia is mainly since people are usually to the length of computer, TV, mobile phone etc.
Phase use, eyes number of winks reduce, cause tears liquid Secretion that should reduce, while scintillation screen intense stimulus eyes and cause
's.
Natural carotenol ester is a kind of important carotenoid aliphatic ester.It is widely present in marigold flower, pumpkin,
In the plants such as wild cabbage, clover.The primary structure of lutein ester is by two six-membered carbon rings by the conjugation of a son Han ten eight carbon atoms
The long-chain of double bond is connected.In digestion process, human body can efficiently hydrolyze lutein ester and release free lutein,
Then it is rapidly absorbed into blood.Studies have shown that the lutein levels in blood and macula retinae can be improved in intake lutein ester,
And the bioavailability for the lutein that lutein ester decomposes is higher than free xanthophyll.
One important biological function of lutein is exactly to protect retina, prevents the damage of ultraviolet light.Currently, whole world hair
Existing senile macular degeneration (AMD) is the main diseases causing blindness of over-65s crowd.After lutein ester is taken in body,
Under the action of body fat enzyme, it is hydrolyzed into the lutein of free state, they are deposited on high concentration in people's fundus flavimaculatus, can be used as
The absorbent of near ultraviolet blue light, by capture free radical, prevent or reduces aoxidize and free radical retina is brought injury by
Defencive function is exercised, the incidence of AMD can be effectively reduced.Supplement lutein can also promote the lymphocyte of antigenic stimulus to increase
Reaction is grown, and the functional expression of cell surface molecule can be influenced, enhances immunization.On May 26th, 2008 ministry of Health of China
Publication bulletin approval lutein ester will become one kind as new resource food, using lutein ester as the exploitation of functional food raw material
Development trend.
Invention content
The purpose of the present invention is to provide a kind of lutein ester composition and preparation for having and alleviating visual fatigue effect, energy
Enough be effectively relieved as caused by asthenopia eye is dry, eye is puckery, the sour swollen, blurred vision of eye even visual impairment the problems such as.
Another object of the present invention is to provide a kind of above-mentioned lutein ester compositions with alleviation visual fatigue effect
Preparation method, preparation method is simple, easily operated, can preferably retain the active ingredient in raw material.
What the embodiment of the present invention was realized in:
A kind of to have the lutein ester composition for alleviating visual fatigue effect, in parts by weight, raw material includes:
10~20 parts of Lutein ester microcapsule powder, 5~10 parts of black fruit fructus lycii, 20~30 parts of blueberry, beta carotene 0.1~0.5
Part, 1~3 part of Cassia occidentalis, 2~4 parts of the shell of seaear, 1~3 part of mulberry leaf and 1~3 part of honeysuckle.
A kind of above-mentioned preparation method with the lutein ester composition for alleviating visual fatigue effect comprising:
Black fruit fructus lycii, blueberry, Cassia occidentalis, the shell of seaear, mulberry leaf and honeysuckle are respectively dried, are crushed into powder, then is yellow with leaf
Plain ester micro capsule powder, beta carotene are mixed.
It is a kind of that there is the preparation for alleviating visual fatigue effect comprising acceptable auxiliary material on above-mentioned composition and food;
Preferably, auxiliary material includes microcrystalline cellulose, maltodextrin, D-sorbite, xylitol, D-mannital, antierythrite, different malt
At least one of ketose alcohol, lactose, magnesium stearate, steviol glycoside or citric acid.
The advantageous effect of the embodiment of the present invention is:
An embodiment of the present invention provides it is a kind of have alleviate visual fatigue effect lutein ester composition and preparation, with
Lutein ester has improving eyesight effect as main component, with black fruit fructus lycii, blueberry, Cassia occidentalis, the shell of seaear, mulberry leaf and honeysuckle etc.
Chinese medicine carry out quantitative compatibility, make to generate apparent synergistic function between each raw material the effective elements of the medicine.Can effectively it delay
Solution eye as caused by asthenopia is dry, eye is puckery, the sour swollen, blurred vision of eye even visual impairment the problems such as.The composition and system
Agent smell, good taste, edible safety, it is without any side effects.
The embodiment of the present invention additionally provides a kind of above-mentioned preparation with the lutein ester composition for alleviating visual fatigue effect
Black fruit fructus lycii, blueberry, Cassia occidentalis, the shell of seaear, mulberry leaf and honeysuckle are respectively dried, are crushed into powder by method, then with lutein ester
Microcapsule powder, beta carotene are mixed.The preparation method is easy to operate, can preferably coordinate the poor taste between each raw material
It is different, and preferably retain the active ingredient in raw material.
Specific implementation mode
It in order to make the object, technical scheme and advantages of the embodiment of the invention clearer, below will be in the embodiment of the present invention
Technical solution be clearly and completely described.The person that is not specified actual conditions in embodiment, builds according to normal condition or manufacturer
The condition of view carries out.Reagents or instruments used without specified manufacturer is the conventional production that can be obtained by commercially available purchase
Product.
There is the lutein ester composition for alleviating visual fatigue effect and its preparation side to a kind of of the embodiment of the present invention below
Method is specifically described.
An embodiment of the present invention provides a kind of lutein ester compositions for having and alleviating visual fatigue effect, according to parts by weight
Meter, raw material include:
10~20 parts of Lutein ester microcapsule powder, 5~10 parts of black fruit fructus lycii, 20~30 parts of blueberry, beta carotene 0.1~0.5
Part, 1~3 part of Cassia occidentalis, 2~4 parts of the shell of seaear, 1~3 part of mulberry leaf and 1~3 part of honeysuckle.
Optionally, in parts by weight, raw material includes:
10~15 parts of Lutein ester microcapsule powder, 5~8 parts of black fruit fructus lycii, 20~25 parts of blueberry, beta carotene 0.3~0.5
Part, 1~2 part of Cassia occidentalis, 2~3 parts of the shell of seaear, 1~2 part of mulberry leaf and 1~2 part of honeysuckle.
Optionally, in parts by weight, raw material includes:
10 parts of Lutein ester microcapsule powder, 5 parts of black fruit fructus lycii, 20 parts of blueberry, 0.5 part of beta carotene, 2 parts of Cassia occidentalis, Shi Jue
1 part of bright 3 parts, 2 parts of mulberry leaf and honeysuckle.
Natural carotenol ester is a kind of important carotenoid aliphatic ester.It is widely present in marigold flower, pumpkin,
In the plants such as wild cabbage, clover.The primary structure of lutein ester is by two six-membered carbon rings by the conjugation of a son Han ten eight carbon atoms
The long-chain of double bond is connected.In digestion process, human body can efficiently hydrolyze lutein ester and release free lutein,
Then it is rapidly absorbed into blood.Studies have shown that the lutein levels in blood and macula retinae can be improved in intake lutein ester,
And the bioavailability for the lutein that lutein ester decomposes is higher than free xanthophyll.One important life of lutein
Object function is exactly to protect retina, prevents the damage of ultraviolet light.After lutein ester is taken in body, in body fat enzyme
Under effect, it is hydrolyzed into the lutein of free state, they are deposited on high concentration in people's fundus flavimaculatus, can be used as near ultraviolet blue light
Absorbent, by capture free radical, prevent or reduces aoxidize and free radical retina is brought injury by exercise defencive function,
The incidence of AMD can effectively be reduced.
Black fruit fructus lycii is the ripening fruits of the more quil shrub black fruit fructus lyciis of Solanaceae Lycium, is rich in anthocyanidin, anthocyanidin
Content reaches 3690mg/100g considerably beyond blueberry.Studies have shown that anthocyanidin can promote in retina cell visual purple again
Growth, long-term consumption can have the function of significantly protecting eyesight have good health-care effect for visual fatigue.Except this with
Outside, modern research shows that black fruit fructus lycii powder pharmacological activity further relates to the following aspects:(1) hypoglycemic, antifatigue, raising body
Immunity;(2) anti-oxidant, removing free radical, oxidation resistance is 50 times of vitamin E;(3) have to tumour and cancer
There are certain prevention and resistant function.
Blueberry contains anthocyanidin, and anthocyanidin is natural potent polyphenoils, anti-eye strain, prevent cranial nerve aging,
Anticancer softening blood vessel, enhances human immunity, has the function of the good internal inflammation of elimination.It can promote impaired collagen egg
White connection, enhancing skin elasticity;Strength removal free radical, avoids peroxide from damaging skin bottom cell, prevents wrinkle and color
Spot is formed.
Beta carotene is a kind of natural carotenoid being widely present in green and yellow vegetable, fruit.β-carrot
After element intake human digestive organ, vitamin A can be converted to.Vitamin A is the photoactive substance for constituting retinal surface, when long
Between stare at computer screen and can consume a large amount of vitamin As.Except prevent yctalopia, xerophthalmia, ulcer of the cornea disease, prevention cataract with
Outside, beta carotene also has the effects that anti-oxidant, removing toxic substances, anticancer, prevention of cardiovascular disease and protection liver.
Cassia occidentalis, also known as cassia seed, nature and flavor are sweet, bitter, salty, be slightly cold.Return liver, large intestine channel.Cassia seed is containing rheum emodin, rheum officinale
Phenol, Physcion, obtusin, obtusin and its glucoside and multivitamin and abundant amino acid, fat, carbon aquation
Close object etc..Cassia seed has clearing away the liver-fire, wind-damp dispelling, tonifying kidney and improving eyesight and other effects, and cassia-tora tea can also clear liver and improve vision, prevent eyesight
It obscures, to lowering blood pressure and blood fat, reduction cholesterol, prevention and treatment of coronary heart disease, high blood pressure have good curative effect:Cassia seed is rich in
Vitamin A and zinc can prevent yctalopia and avoid zinc deficiency in children.
Shell of seaear nature and flavor are micro- salty, are slightly cold.Return liver, lung channel.Shell of seaear calcium carbonate, also containing organic matter and a small amount of magnesium, iron,
The iodine of silicate, sulfate, phosphate, chloride and denier.Shell of seaear clearing liver checking exuberance of yang, removing nebula for improving eyesight;Energy removing heat from the liver, tonifying liver
The moon, the diseases such as dizziness, twitch, cataract, glaucoma night blindness that can be used for caused by the only high or yin deficiency yang hyperactivity of liver-yang, and energy clearind deficient heat,
Have and controls low-heat of pulmonary tuberculosis and other effects.
Mulberry leaf nature and flavor are sweet, bitter, tremble with fear.Channel tropism return lung, Liver Channel.Major function dispelling wind and heat from the body, clearing away the lungheat and moisturizing are clear liver and improved vision.It can
For treating anemopyretic cold, lung-heat type cough, dizziness headache, the symptoms such as hot eyes is dim-sighted.
Honeysuckle nature and flavor are sweet, tremble with fear.Return lung, the heart, stomach.With heat-clearing improving eyesight, the effect of wind-heat dissipating, strengthen immunity.
It can be used for carbuncle swells and treat sore, larynx numbness, erysipelas, toxic-heat and blood stasis, anemopyretic cold, the symptoms such as warm disease heating.
Above-mentioned medicinal material is based on sweet taste, and mouthfeel is coordinated after mixing, smell, good taste.Meanwhile above-mentioned medicinal material
Preferable function of improving eyesight is all had, is used cooperatively down, can be synergistic, it is effectively relieved that the eye as caused by asthenopia is dry, eye
The problems such as puckery, sour swollen, blurred vision of eye or even visual impairment.
Required preparation can be made in above-mentioned composition with acceptable auxiliary material on food, and the dosage form of preparation is granule, powder
Any one in agent, capsule, tablet or oral solution.
Auxiliary material includes microcrystalline cellulose, maltodextrin, D-sorbite, xylitol, D-mannital, antierythrite, different wheat
At least one of bud ketose alcohol, lactose, magnesium stearate, steviol glycoside or citric acid.
Preferably, in parts by weight, said preparation includes:
10~20 parts of Lutein ester microcapsule powder, 5~10 parts of black fruit fructus lycii, 20~30 parts of blueberry, beta carotene 0.1~0.5
Part, 1~3 part of Cassia occidentalis, 2~4 parts of the shell of seaear, 1~3 part of mulberry leaf, 1~3 part of honeysuckle, 10~20 parts of microcrystalline cellulose, lactose
0.1~1 part of 20~30 parts, 10~20 parts of xylitol, 10~20 parts of D-mannital and magnesium stearate.Said preparation is tablet.
The embodiment of the present invention additionally provides a kind of above-mentioned preparation with the lutein ester composition for alleviating visual fatigue effect
Method comprising:
Black fruit fructus lycii, blueberry, Cassia occidentalis, the shell of seaear, mulberry leaf and honeysuckle are respectively dried, are crushed into powder, then is yellow with leaf
Plain ester micro capsule powder, beta carotene are mixed.
Wherein, the temperature dried to black fruit fructus lycii, blueberry, Cassia occidentalis, the shell of seaear, mulberry leaf and honeysuckle is 100~
130℃.The effect of drying is the moisture removed in above-mentioned raw materials, and above-mentioned raw materials is allow to be preserved for a long time.The temperature of drying
Degree is unsuitable excessively high, on the one hand needs to avoid high temperature that raw material is made to be charred influence mouthfeel, on the other hand to avoid high temperature to nutritional ingredient
Destruction.
Further, after black fruit fructus lycii, blueberry, Cassia occidentalis, the shell of seaear, mulberry leaf and the honeysuckle after drying being crushed, mistake
110~130 mesh sieve, and extracting screen underflow is mixed.Above-mentioned raw materials are pulverized and sieved can more fully between can making each component
Mixing, reach preferably synergistic function.
Stone is clear and decided once to soak 1~3h in preliminary crushing and after cleaning, and continues 0.5~1h of boiling after boiling and goes
Except decoction liquor, then secondary plus water, 0.5~1h is boiled, goes after decoction liquor to be dried again, crush.Clear and decided stone is Bao Ke animals
Shell, quality is hard, needs first to carry out preliminary crushing well-done, well-done, could preferably carry out following process.
By black fruit fructus lycii, blueberry, Cassia occidentalis, the shell of seaear, mulberry leaf and the powder of the honeysuckle frying 10 after crushing~
20min.It after above-mentioned raw materials powder frying, can not only make it well-done in advance, be conducive to eat, while can tart up, change
Kind mouthfeel.The temperature of frying is unsuitable excessively high, and medicinal ingredient is avoided to be destroyed.
The feature and performance of the present invention are described in further detail with reference to embodiments.
Embodiment 1
A kind of preparation for having and alleviating visual fatigue effect is present embodiments provided, said preparation is pulvis, and raw material includes:
Lutein ester microcapsule powder 100g, black fruit fructus lycii 50g, blueberry 300g, beta carotene 5g, Cassia occidentalis 10g, the shell of seaear
20g, mulberry leaf 30g and honeysuckle 30g.
Preparation method includes:
(1) it dried after black fruit fructus lycii, blueberry, Cassia occidentalis, mulberry leaf, honeysuckle being taken impurity, cleaned, crushed 110 mesh sieve,
It is spare.
(2) shell of seaear is placed in container, one decocts plus water crosses 4~8cm of material face, steeps 2h, with boiling with stirring, water is opened
Decoction liquor is poured out after 60min, two decoct added water 4~8cm of material face, with boiling with stirring, water falls decoction liquor after opening 45min
Go out, filter is net, and filter residue is spare.
(3) by each material after crushing in (1) together with the filter residue in (2) 10~20min of frying, fry stir well it is even after,
130 mesh sieve is crushed, mixed-powder is obtained.
(4) it is uniformly mixed with Lutein ester microcapsule powder and beta carotene after the mixed-powder in (3) dries in the air to room temperature.
Embodiment 2
A kind of preparation for having and alleviating visual fatigue effect is present embodiments provided, said preparation is pulvis comprising:
Lutein ester microcapsule powder 200g, black fruit fructus lycii 100g, blueberry 200g, beta carotene 1g, Cassia occidentalis 30g, the shell of seaear
40g, mulberry leaf 10g and honeysuckle 10g.
Preparation method is with reference to shown in embodiment 1.
Embodiment 3
A kind of preparation for having and alleviating visual fatigue effect is present embodiments provided, said preparation is tablet comprising:
Lutein ester microcapsule powder 150g, black fruit fructus lycii 70g, blueberry 250g, beta carotene 3g, Cassia occidentalis 20g, the shell of seaear
30g, mulberry leaf 20g, honeysuckle 20g, microcrystalline cellulose 100g, lactose 300g, xylitol 100g, D-mannital 200g and
Magnesium stearate 1g.
Preparation method includes:
(1) it dried after black fruit fructus lycii, blueberry, Cassia occidentalis, mulberry leaf, honeysuckle being removed impurity, cleaned, crushed 110 mesh
Sieve, it is spare.
(2) shell of seaear is placed in container, one decocts plus water crosses 4~8cm of material face, steeps 2h, with boiling with stirring, water is opened
Decoction liquor is poured out after 60min, two decoct added water 4~8cm of material face, with boiling with stirring, water falls decoction liquor after opening 45min
Go out, filter is net, and filter residue is spare.
(3) by each material after crushing in (1) together with the filter residue in (2) 10~20min of frying, fry stir well it is even after,
130 mesh sieve is crushed, mixed-powder is obtained.
(4) it is mixed with Lutein ester microcapsule powder, beta carotene and auxiliary material after the mixed-powder in (3) dries in the air to room temperature
It is tabletted after uniformly.
Embodiment 4
A kind of preparation for having and alleviating visual fatigue effect is present embodiments provided, said preparation is tablet comprising:
Lutein ester microcapsule powder 100g, black fruit fructus lycii 50g, blueberry 200g, beta carotene 5g, Cassia occidentalis 20g, the shell of seaear
30g, mulberry leaf 20g, honeysuckle 10g, microcrystalline cellulose 200g, maltodextrin 200g, D-sorbite 200g and magnesium stearate
10g。
Preparation method is with reference to shown in embodiment 3.
Test example
Select Examples 1 to 4 provided have alleviate visual fatigue effect lutein ester composition, Beijing, Shanghai,
Random sampling is done in Guangzhou, Shenzhen, Chengdu and 6, Chongqing place, alleviates visual fatigue effect for having for each embodiment
Lutein ester composition select 20 users in each place and test and track interview.Experiment 3 months by a definite date, 3
After the moon is full, questionnaire survey is carried out to every user, for the functional food in taste mouthfeel, convenient degree, therapeutic effect
Three aspects score, and full marks 10 divide, and user gives according to actual conditions to be divided, and to the functional food of each embodiment
Amount to the number that 120 users are given to average, result of calculation is as shown in table 1.
What 1 Examples 1 to 4 of table was provided has the lutein ester composition effect for alleviating visual fatigue effect
Fruit scores
As it can be seen from table 1 the lutein ester group with alleviation visual fatigue effect that the embodiment of the present invention 1~4 is provided
Object is closed in terms of therapeutic effect, client's Basic Authorization remission effect to asthenopia of the product, average mark 9.1 or so.Together
When, client also gives very high evaluation in terms of taste mouthfeel and convenient degree, and especially tablet (embodiment 3,4) is in taste
Evaluation in road mouthfeel and portable degree has reached 9.5 or so.
In conclusion an embodiment of the present invention provides it is a kind of have alleviate visual fatigue effect lutein ester composition and
Preparation, using lutein ester as main component, with the tools such as black fruit fructus lycii, blueberry, Cassia occidentalis, the shell of seaear, mulberry leaf and honeysuckle
There is the Chinese medicine of improving eyesight effect to carry out quantitative compatibility, makes to generate apparent synergistic function between each raw material the effective elements of the medicine.
Can be effectively relieved as caused by asthenopia eye is dry, eye is puckery, the sour swollen, blurred vision of eye even visual impairment the problems such as.The group
Object and preparation smell, good taste, edible safety are closed, it is without any side effects.
The embodiment of the present invention additionally provides a kind of above-mentioned preparation with the lutein ester composition for alleviating visual fatigue effect
Black fruit fructus lycii, blueberry, Cassia occidentalis, the shell of seaear, mulberry leaf and honeysuckle are respectively dried, are crushed into powder by method, then with lutein ester
Microcapsule powder, beta carotene are mixed.The preparation method is easy to operate, can preferably coordinate the poor taste between each raw material
It is different, and preferably retain the active ingredient in raw material.
The foregoing is only a preferred embodiment of the present invention, is not intended to restrict the invention, for the skill of this field
For art personnel, the invention may be variously modified and varied.All within the spirits and principles of the present invention, any made by repair
Change, equivalent replacement, improvement etc., should all be included in the protection scope of the present invention.
Claims (10)
1. a kind of having the lutein ester composition for alleviating visual fatigue effect, which is characterized in that in parts by weight, raw material
Including:
10~20 parts of Lutein ester microcapsule powder, 5~10 parts of black fruit fructus lycii, 20~30 parts of blueberry, 0.1~0.5 part of beta carotene,
1~3 part of 1~3 part of Cassia occidentalis, 2~4 parts of the shell of seaear, 1~3 part of mulberry leaf and honeysuckle.
2. according to claim 1 have the lutein ester composition for alleviating visual fatigue effect, which is characterized in that according to weight
Number meter is measured, raw material includes:
10~15 parts of the Lutein ester microcapsule powder, 5~8 parts of the black fruit fructus lycii, 20~25 parts of the blueberry, the β-Hu Luo
0.3~0.5 part of Bu Su, 1~2 part of the Cassia occidentalis, 2~3 parts of the shell of seaear, 1~2 part of the mulberry leaf and the honeysuckle
1~2 part.
3. according to claim 3 have the lutein ester composition for alleviating visual fatigue effect, which is characterized in that according to weight
Number meter is measured, raw material includes:
10 parts of the Lutein ester microcapsule powder, 5 parts of the black fruit fructus lycii, 20 parts of the blueberry, 0.5 part of the beta carotene, institute
State 1 part of 2 parts of Cassia occidentalis, 3 parts of the shell of seaear, 2 parts of the mulberry leaf and the honeysuckle.
4. a kind of preparation such as claims 1 to 3 any one of them with the lutein ester composition for alleviating visual fatigue effect
Method, which is characterized in that including:
The black fruit fructus lycii, the blueberry, the Cassia occidentalis, the shell of seaear, the mulberry leaf and the honeysuckle are dried respectively
It does, be crushed into powder, then mixed with the Lutein ester microcapsule powder, the beta carotene.
5. preparation method according to claim 4, which is characterized in that determine to the black fruit fructus lycii, the blueberry, the grass
The temperature that bright, the described shell of seaear, the mulberry leaf and the honeysuckle are dried is 100~130 DEG C.
6. preparation method according to claim 5, which is characterized in that by after drying the black fruit fructus lycii, the blueberry,
After the Cassia occidentalis, the shell of seaear, the mulberry leaf and the honeysuckle crush, 110~130 mesh sieve is crossed, extracting screen underflow carries out
Mixing.
7. preparation method according to claim 6, which is characterized in that the stone it is clear and decided preliminary crushing and clean after,
1~3h once is soaked, continues 0.5~1h of boiling after boiling and removes decoction liquor, then secondary plus water, boil 0.5~1h, go to decoct
It dried, crushed again after boil liquid.
8. preparation method according to claim 7, which is characterized in that by after crushing the black fruit fructus lycii, the blueberry,
The Cassia occidentalis, 10~20min of the shell of seaear, the mulberry leaf and the powder frying of the honeysuckle.
9. a kind of having the preparation for alleviating visual fatigue effect, which is characterized in that it includes as described in any one of claims 1 to 3
Composition and food in acceptable auxiliary material;Preferably, the auxiliary material includes microcrystalline cellulose, maltodextrin, sorbose
In alcohol, xylitol, D-mannital, antierythrite, isomalt, lactose, magnesium stearate, steviol glycoside or citric acid
It is at least one.
10. preparation according to claim 9, which is characterized in that the dosage form of the preparation be granule, pulvis, capsule,
Any one in tablet or oral solution.
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