CN101426536A - 治疗、预防和诊断骨病变的方法 - Google Patents

治疗、预防和诊断骨病变的方法 Download PDF

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Publication number
CN101426536A
CN101426536A CNA2007800027816A CN200780002781A CN101426536A CN 101426536 A CN101426536 A CN 101426536A CN A2007800027816 A CNA2007800027816 A CN A2007800027816A CN 200780002781 A CN200780002781 A CN 200780002781A CN 101426536 A CN101426536 A CN 101426536A
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bone
gene
expression
gpc3
rbp4
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Chinese (zh)
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A·K·库森斯
A·M·范达尔
B·C·鲍威尔
P·J·安德森
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CHILD HEALTH RES INST Inc
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CHILD HEALTH RES INST Inc
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Priority claimed from AU2006900307A external-priority patent/AU2006900307A0/en
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Publication of CN101426536A publication Critical patent/CN101426536A/zh
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    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
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    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physical Education & Sports Medicine (AREA)
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  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biophysics (AREA)
  • General Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Oncology (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
CNA2007800027816A 2006-01-20 2007-01-19 治疗、预防和诊断骨病变的方法 Pending CN101426536A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
AU2006900307 2006-01-20
AU2006900307A AU2006900307A0 (en) 2006-01-20 Method of treatment and diagnosis

Publications (1)

Publication Number Publication Date
CN101426536A true CN101426536A (zh) 2009-05-06

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CNA2007800027816A Pending CN101426536A (zh) 2006-01-20 2007-01-19 治疗、预防和诊断骨病变的方法

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US (1) US20100330085A1 (enExample)
EP (1) EP1991274A4 (enExample)
JP (1) JP2009523739A (enExample)
CN (1) CN101426536A (enExample)
AU (1) AU2007207341B2 (enExample)
CA (1) CA2637350A1 (enExample)
NZ (1) NZ569697A (enExample)
WO (1) WO2007082352A1 (enExample)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114657121A (zh) * 2022-03-23 2022-06-24 新乡医学院 LOX1基因作为流体剪切力作用下BMSCs成骨分化促进剂的应用
CN114774546A (zh) * 2022-04-27 2022-07-22 江苏省人民医院（南京医科大学第一附属医院） 一种与人骨肉瘤相关的分子标记物trim22及其应用

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GB0707349D0 (en) * 2007-04-17 2007-05-23 Renovo Ltd Medicaments and methods for accelerating wound healing
EP2167976A2 (en) * 2007-05-29 2010-03-31 President And Fellows Of Harvard College Molecules involved in regulation of osteoblast activity and osteoclast activity, and methods of use thereof
JP5694776B2 (ja) * 2007-12-11 2015-04-01 エピゲノミクス アーゲー 細胞増殖性障害の解析のための方法及び核酸
EP2245459A1 (en) 2008-01-23 2010-11-03 Herlev Hospital Ykl-40 as a general marker for non-specific disease
US8580520B2 (en) 2008-09-15 2013-11-12 Herlev Hospital YKL-40 as a marker for gastrointestinal cancers
GB0922085D0 (en) * 2009-12-17 2010-02-03 Cambridge Entpr Ltd Cancer diagnosis and treatment
WO2011088163A1 (en) 2010-01-14 2011-07-21 President And Fellows Of Harvard College Methods for modulating skeletal remodeling and patterning by modulating shn2 activity, shn3 activity, or shn2 and shn3 activity in combination
EP2556379B1 (en) * 2010-10-28 2014-07-09 Avicenna Research Institute A 38 kda form of prelp as new diagnosis and therapeutic target
US20140155420A1 (en) * 2011-01-10 2014-06-05 The Regents Of The University Of Colorado, A Body Corporate Inhibitors of eya2
CN103517717B (zh) * 2011-02-16 2017-10-17 康奈尔大学 增强细胞介导的免疫的方法
AU2012253204A1 (en) * 2011-05-06 2013-04-18 Women's And Children's Health Research Institute Inc Method of treatment and prophylaxis of pathologies of the bone
CN109295218B (zh) * 2018-12-11 2020-05-19 南京医科大学 环状RNA标志物hsa_circ_0001788及其应用
CN114015767B (zh) * 2021-11-18 2023-06-02 南京市儿童医院 一种鉴别颅缝早闭的血清circRNA标志物及其应用
CN116217721A (zh) * 2023-02-16 2023-06-06 复旦大学附属中山医院 一种C14orf78免疫组织化学抗体及其制备方法与应用

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114657121A (zh) * 2022-03-23 2022-06-24 新乡医学院 LOX1基因作为流体剪切力作用下BMSCs成骨分化促进剂的应用
CN114657121B (zh) * 2022-03-23 2023-07-25 新乡医学院 LOX1基因作为流体剪切力作用下BMSCs成骨分化促进剂的应用
CN114774546A (zh) * 2022-04-27 2022-07-22 江苏省人民医院（南京医科大学第一附属医院） 一种与人骨肉瘤相关的分子标记物trim22及其应用

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Publication number Publication date
JP2009523739A (ja) 2009-06-25
EP1991274A4 (en) 2009-06-10
AU2007207341A1 (en) 2007-07-26
NZ569697A (en) 2012-01-12
AU2007207341B2 (en) 2012-05-10
US20100330085A1 (en) 2010-12-30
CA2637350A1 (en) 2007-07-26
EP1991274A1 (en) 2008-11-19
WO2007082352A1 (en) 2007-07-26

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Application publication date: 20090506