CN101406457A - 制备药物产品的方法 - Google Patents

制备药物产品的方法 Download PDF

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Publication number
CN101406457A
CN101406457A CNA2007101860236A CN200710186023A CN101406457A CN 101406457 A CN101406457 A CN 101406457A CN A2007101860236 A CNA2007101860236 A CN A2007101860236A CN 200710186023 A CN200710186023 A CN 200710186023A CN 101406457 A CN101406457 A CN 101406457A
Authority
CN
China
Prior art keywords
potassium bicarbonate
diameter
granular size
sodium picosulfate
particulate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CNA2007101860236A
Other languages
English (en)
Chinese (zh)
Inventor
徐海军
刁铁军
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ferring International Center (switzerland) S A
Ferring International Center SA
Original Assignee
Ferring International Center (switzerland) S A
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ferring International Center (switzerland) S A filed Critical Ferring International Center (switzerland) S A
Priority to KR1020137023315A priority Critical patent/KR101381263B1/ko
Priority to NZ583899A priority patent/NZ583899A/en
Priority to MX2010003588A priority patent/MX2010003588A/es
Priority to LTEP08837670.2T priority patent/LT2207526T/lt
Priority to US12/677,857 priority patent/US8481083B2/en
Priority to EP08837670.2A priority patent/EP2207526B1/en
Priority to JP2010528503A priority patent/JP5654873B2/ja
Priority to DK08837670.2T priority patent/DK2207526T3/da
Priority to PL08837670T priority patent/PL2207526T3/pl
Priority to PCT/IB2008/003199 priority patent/WO2009047633A2/en
Priority to BRPI0818541A priority patent/BRPI0818541B8/pt
Priority to ES08837670.2T priority patent/ES2659716T3/es
Priority to HUE08837670A priority patent/HUE038174T2/hu
Priority to SI200831915T priority patent/SI2207526T1/en
Priority to PT88376702T priority patent/PT2207526T/pt
Priority to KR1020107007932A priority patent/KR101330096B1/ko
Priority to RU2010112483/15A priority patent/RU2473332C2/ru
Priority to AU2008309287A priority patent/AU2008309287B2/en
Priority to CA2702152A priority patent/CA2702152A1/en
Publication of CN101406457A publication Critical patent/CN101406457A/zh
Priority to IL204500A priority patent/IL204500A/en
Priority to ZA2010/02131A priority patent/ZA201002131B/en
Priority to US13/246,739 priority patent/US8450338B2/en
Priority to HRP20180215TT priority patent/HRP20180215T1/hr
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/009—Sachets, pouches characterised by the material or function of the envelope
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CNA2007101860236A 2007-10-12 2007-11-09 制备药物产品的方法 Pending CN101406457A (zh)

Priority Applications (23)

Application Number Priority Date Filing Date Title
ES08837670.2T ES2659716T3 (es) 2007-10-12 2008-10-10 Proceso para la fabricación de un producto farmacéutico que comprende ácido cítrico, óxido de magnesio, bicarbonato potásico y picosulfato sódico, composición farmacéutica que comprende gránulos obtenidos por tal proceso y productos intermedios de la misma
SI200831915T SI2207526T1 (en) 2007-10-12 2008-10-10 A process for the manufacture of a pharmaceutical product comprising citric acid, magnesium oxide, potassium bicarbonate and sodium picosulfate, a pharmaceutical composition comprising the granules obtained according to such a process and its intermediates
HUE08837670A HUE038174T2 (hu) 2007-10-12 2008-10-10 Eljárás citromsavat, magnéziumoxidot, káliumbikarbonátot és nátriumpikoszulfátot tartalmazó gyógyszertermék elõállítására, ilyen eljárással elõállított szemcsés gyógyászati készítmény és köztitermékei
LTEP08837670.2T LT2207526T (lt) 2007-10-12 2008-10-10 Farmacinio produkto, apimančio citrinų rūgštį, magnio oksidą, kalio bikarbonatą ir natrio pikosulfatą, gavimo būdas, farmacinės kompozicijos, apimančios granules, gautas šiuo būdu, ir jų tarpiniai produktai
NZ583899A NZ583899A (en) 2007-10-12 2008-10-10 Process for the manufacure of a pharmaceutical product comprising citric acid, magnesium oxide, potassium bicarbonate and sodium picosulfate, pharmaceutical composition comprising granules obtained by such process and intermediate
EP08837670.2A EP2207526B1 (en) 2007-10-12 2008-10-10 Process for the manufacure of a pharmaceutical product comprising citric acid, magnesium oxide, potassium bicarbonate and sodium picosulfate, pharmaceutical composition comprising granules obtained by such process and intermediate products thereof
JP2010528503A JP5654873B2 (ja) 2007-10-12 2008-10-10 医薬品を製造する方法
PT88376702T PT2207526T (pt) 2007-10-12 2008-10-10 Resumo
PL08837670T PL2207526T3 (pl) 2007-10-12 2008-10-10 Sposób wytwarzania produktu farmaceutycznego zawierającego kwas cytrynowy, tlenek magnezu, wodorowęglan potasu i pikosiarczan sodu, kompozycja farmaceutyczna zawierająca granulki otrzymane takim sposobem i jego produkty pośrednie
PCT/IB2008/003199 WO2009047633A2 (en) 2007-10-12 2008-10-10 Process for the manufacure of a pharmaceutical product comprising citric acid, magnesium oxide, potassium bicarbonate and sodium picosulfate, pharmaceutical composition comprising granules obtained by such process and intermediate
BRPI0818541A BRPI0818541B8 (pt) 2007-10-12 2008-10-10 composição farmacêutica que compreende grânulos incluindo picossulfato de sódio e bicarbonato de potássio e seu processo para a preparação
KR1020137023315A KR101381263B1 (ko) 2007-10-12 2008-10-10 구연산, 산화 마그네슘, 중탄산칼륨 및 피코황산나트륨을 포함하는 의약품의 제조 방법, 이러한 방법에 의해 제조된 과립을 포함하는 약제학적 조성물 및 중간체
MX2010003588A MX2010003588A (es) 2007-10-12 2008-10-10 Proceso para la manufactura de un producto farmaceutico.
US12/677,857 US8481083B2 (en) 2007-10-12 2008-10-10 Granular compositions of magnesium oxide and citric acid and uses thereof
DK08837670.2T DK2207526T3 (da) 2007-10-12 2008-10-10 Fremgangsmåde til fremstilling af et farmaceutisk produkt omfattende citronsyre, magnesiumoxid, kaliumbicarbonat og natriumpicosulfat, farmaceutisk sammensætning omfattende granuler opnået ved sådanne fremgangsmåder og mellemprodukter deraf.
KR1020107007932A KR101330096B1 (ko) 2007-10-12 2008-10-10 구연산, 산화 마그네슘, 중탄산칼륨 및 피코황산나트륨을 포함하는 의약품의 제조 방법, 이러한 방법에 의해 제조된 과립을 포함하는 약제학적 조성물 및 중간체
RU2010112483/15A RU2473332C2 (ru) 2007-10-12 2008-10-10 Способ изготовления фармацевтического продукта, содержащего лимонную кислоту, оксид магния, бикарбонат калия и пикосульфат натрия, фармацевтические композиции, содержащие гранулы, полученные таким способом, и промежуточное соединение
AU2008309287A AU2008309287B2 (en) 2007-10-12 2008-10-10 Process for the manufacure of a pharmaceutical product comprising citric acid, magnesium oxide, potassium bicarbonate and sodium picosulfate, pharmaceutical composition comprising granules obtained by such process and intermediate
CA2702152A CA2702152A1 (en) 2007-10-12 2008-10-10 Process for the manufacture of a pharmaceutical product
IL204500A IL204500A (en) 2007-10-12 2010-03-15 Process for manufacturing vehicle or pharmacist composition by spraying a coating of sodium picosulphate on a nucleus of potassium bicarbonate
ZA2010/02131A ZA201002131B (en) 2007-10-12 2010-03-25 Process for the manufacture of a pharmaceutical product comprising citric acid,magnesium oxide,potassium bicarbonate and sodium picosulfate,pharmaceutical composition comprising granules obtained by such process and intermediate
US13/246,739 US8450338B2 (en) 2007-10-12 2011-09-27 Granular compositions of sodium picosulphate and potassium bicarbonate and uses thereof
HRP20180215TT HRP20180215T1 (hr) 2007-10-12 2018-02-05 Postupak za proizvodnju farmaceutskog proizvoda koji sadrži limunsku kiselinu, magnezijev oksid, kalijev bikarbonat i natrijev pikosulfat, farmaceutski pripravak koji sadrži granule dobivene takvim postupkom i njihovi međuproizvodi

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP07254049.5 2007-10-12
EP07254049 2007-10-12
US60/980,549 2007-10-17

Publications (1)

Publication Number Publication Date
CN101406457A true CN101406457A (zh) 2009-04-15

Family

ID=39672123

Family Applications (1)

Application Number Title Priority Date Filing Date
CNA2007101860236A Pending CN101406457A (zh) 2007-10-12 2007-11-09 制备药物产品的方法

Country Status (2)

Country Link
CN (1) CN101406457A (ar)
SA (1) SA08290670B1 (ar)

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104797244A (zh) * 2012-07-27 2015-07-22 红山生物医药有限公司 用于结肠排空的制剂和制备制剂方法
CN105228634A (zh) * 2013-05-17 2016-01-06 协和化学工业株式会社 用于大肠检查或手术的处理剂和处理方法
CN105456264A (zh) * 2015-12-03 2016-04-06 广州瑞尔医药科技有限公司 双效缓泻的药物组合物及其制备方法
CN110638786A (zh) * 2019-10-09 2020-01-03 杭州百诚医药科技股份有限公司 一种匹可硫酸钠与枸橼酸、氧化镁的药物组合物及制备方法
CN115040512A (zh) * 2022-07-28 2022-09-13 苏州中化药品工业有限公司 一种药物组合物及其制备方法
CN115337271A (zh) * 2022-09-30 2022-11-15 山东创新药物研发有限公司 一种匹可硫酸钠颗粒制剂及其制备工艺

Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104797244A (zh) * 2012-07-27 2015-07-22 红山生物医药有限公司 用于结肠排空的制剂和制备制剂方法
CN104797244B (zh) * 2012-07-27 2018-03-09 红山生物医药有限公司 用于结肠排空的制剂和制备制剂方法
CN108175773A (zh) * 2012-07-27 2018-06-19 红山生物医药有限公司 用于结肠排空的制剂和制备制剂方法
US10493065B2 (en) 2012-07-27 2019-12-03 Redhill Biopharma Ltd. Formulations and methods of manufacturing formulations for use in colonic evacuation
CN105228634A (zh) * 2013-05-17 2016-01-06 协和化学工业株式会社 用于大肠检查或手术的处理剂和处理方法
CN105456264A (zh) * 2015-12-03 2016-04-06 广州瑞尔医药科技有限公司 双效缓泻的药物组合物及其制备方法
CN105456264B (zh) * 2015-12-03 2018-07-10 广州瑞尔医药科技有限公司 双效缓泻的药物组合物及其制备方法
CN110638786A (zh) * 2019-10-09 2020-01-03 杭州百诚医药科技股份有限公司 一种匹可硫酸钠与枸橼酸、氧化镁的药物组合物及制备方法
CN115040512A (zh) * 2022-07-28 2022-09-13 苏州中化药品工业有限公司 一种药物组合物及其制备方法
CN115337271A (zh) * 2022-09-30 2022-11-15 山东创新药物研发有限公司 一种匹可硫酸钠颗粒制剂及其制备工艺

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Open date: 20090415