CN101400674A - 抗生素化合物 - Google Patents

抗生素化合物 Download PDF

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Publication number
CN101400674A
CN101400674A CNA2007800084306A CN200780008430A CN101400674A CN 101400674 A CN101400674 A CN 101400674A CN A2007800084306 A CNA2007800084306 A CN A2007800084306A CN 200780008430 A CN200780008430 A CN 200780008430A CN 101400674 A CN101400674 A CN 101400674A
Authority
CN
China
Prior art keywords
pyrans
tetrahydrochysene
fluoro
phenyl
methoxyl group
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CNA2007800084306A
Other languages
English (en)
Chinese (zh)
Inventor
吉恩-克里斯托福·高维恩
克里斯蒂安·哈伯舒兰
让-菲利普·斯维特
科内丽亚·扎姆布朗恩·埃科林
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Actelion Pharmaceuticals Ltd
Original Assignee
Actelion Pharmaceuticals Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Actelion Pharmaceuticals Ltd filed Critical Actelion Pharmaceuticals Ltd
Publication of CN101400674A publication Critical patent/CN101400674A/zh
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Health & Medical Sciences (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
CNA2007800084306A 2006-03-10 2007-03-09 抗生素化合物 Pending CN101400674A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IBPCT/IB2006/050762 2006-03-10
IB2006050762 2006-03-10

Publications (1)

Publication Number Publication Date
CN101400674A true CN101400674A (zh) 2009-04-01

Family

ID=38267680

Family Applications (1)

Application Number Title Priority Date Filing Date
CNA2007800084306A Pending CN101400674A (zh) 2006-03-10 2007-03-09 抗生素化合物

Country Status (5)

Country Link
EP (1) EP1996579A2 (fr)
JP (1) JP2009529525A (fr)
CN (1) CN101400674A (fr)
CA (1) CA2643962A1 (fr)
WO (1) WO2007105154A2 (fr)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2020063618A1 (fr) * 2018-09-27 2020-04-02 深圳微芯生物科技股份有限公司 Dérivé de quinolone ayant une activité inhibée par l'indoléamine-2,3-dioxygénase
CN115677708A (zh) * 2022-10-19 2023-02-03 五邑大学 一种吡咯并喹喔啉的制备方法

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR067008A1 (es) * 2007-06-15 2009-09-30 Actelion Pharmaceuticals Ltd Derivados 3- amino-6-(1- amino - etil)-tetrahidropirano
EP2245028B1 (fr) 2007-12-18 2012-02-22 Actelion Pharmaceuticals Ltd. Dérivés 5-aminocyclylméthyloxazolidin-2-one
NZ593891A (en) 2008-12-12 2013-05-31 Actelion Pharmaceuticals Ltd 5-amino-2-(1-hydroxy-ethyl)-tetrahydropyran derivatives

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE463494T1 (de) * 2002-10-10 2010-04-15 Morphochem Ag Komb Chemie Neue verbindungen mit antibakterieller aktivität
DE10316081A1 (de) * 2003-04-08 2004-10-21 Morphochem AG Aktiengesellschaft für kombinatorische Chemie Neue Verbindungen mit antibakterieller Aktivität
CA2580621A1 (fr) * 2004-09-24 2006-03-30 Actelion Pharmaceuticals Ltd Nouveaux antibiotiques bicycliques
MX2007014507A (es) * 2005-05-24 2008-02-07 Astrazeneca Ab Aminopiperidin quinolinas y sus analogos azaisostericos con actividad antibacteriana.
ES2376488T3 (es) * 2006-01-26 2012-03-14 Actelion Pharmaceuticals Ltd. Antibióticos de tetrahidropirano.

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2020063618A1 (fr) * 2018-09-27 2020-04-02 深圳微芯生物科技股份有限公司 Dérivé de quinolone ayant une activité inhibée par l'indoléamine-2,3-dioxygénase
CN115677708A (zh) * 2022-10-19 2023-02-03 五邑大学 一种吡咯并喹喔啉的制备方法

Also Published As

Publication number Publication date
EP1996579A2 (fr) 2008-12-03
WO2007105154A2 (fr) 2007-09-20
WO2007105154A3 (fr) 2007-12-13
JP2009529525A (ja) 2009-08-20
CA2643962A1 (fr) 2007-09-20

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Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C02 Deemed withdrawal of patent application after publication (patent law 2001)
WD01 Invention patent application deemed withdrawn after publication

Application publication date: 20090401