CN101384734B - 正常和异常基因表达中的dna构象(环结构) - Google Patents
正常和异常基因表达中的dna构象(环结构) Download PDFInfo
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- CN101384734B CN101384734B CN2007800057991A CN200780005799A CN101384734B CN 101384734 B CN101384734 B CN 101384734B CN 2007800057991 A CN2007800057991 A CN 2007800057991A CN 200780005799 A CN200780005799 A CN 200780005799A CN 101384734 B CN101384734 B CN 101384734B
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- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6809—Methods for determination or identification of nucleic acids involving differential detection
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- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
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- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0603251.0 | 2006-02-17 | ||
| GBGB0603251.0A GB0603251D0 (en) | 2006-02-17 | 2006-02-17 | DNA conformation |
| PCT/GB2007/000564 WO2007093819A2 (en) | 2006-02-17 | 2007-02-19 | Dna conformation (loop structures) in normal and abnormal gene expression |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN101384734A CN101384734A (zh) | 2009-03-11 |
| CN101384734B true CN101384734B (zh) | 2013-10-30 |
Family
ID=36142050
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2007800057991A Active CN101384734B (zh) | 2006-02-17 | 2007-02-19 | 正常和异常基因表达中的dna构象(环结构) |
Country Status (15)
| Country | Link |
|---|---|
| US (2) | US9777327B2 (https=) |
| EP (1) | EP1991697B1 (https=) |
| JP (1) | JP5345857B2 (https=) |
| CN (1) | CN101384734B (https=) |
| AT (1) | ATE519864T1 (https=) |
| AU (1) | AU2007216315B2 (https=) |
| CA (1) | CA2642331C (https=) |
| DK (1) | DK1991697T3 (https=) |
| ES (1) | ES2368767T3 (https=) |
| GB (1) | GB0603251D0 (https=) |
| MY (1) | MY182608A (https=) |
| NO (1) | NO343718B1 (https=) |
| NZ (1) | NZ571201A (https=) |
| WO (1) | WO2007093819A2 (https=) |
| ZA (1) | ZA200807948B (https=) |
Families Citing this family (58)
| Publication number | Priority date | Publication date | Assignee | Title |
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| GB0603251D0 (en) | 2006-02-17 | 2006-03-29 | Isis Innovation | DNA conformation |
| AU2009207922B2 (en) | 2008-01-23 | 2015-05-14 | Herlev Hospital | YKL-40 as a general marker for non-specific disease |
| GB0810051D0 (en) * | 2008-06-02 | 2008-07-09 | Oxford Biodynamics Ltd | Method of diagnosis |
| NZ592241A (en) | 2008-09-15 | 2012-11-30 | Herlev Hospital | Ykl-40 as a marker for gastrointestinal cancers |
| WO2012005595A2 (en) * | 2010-07-09 | 2012-01-12 | Wouter Leonard De Laat | V3-d genomic region of interest sequencing strategies |
| US9701998B2 (en) | 2012-12-14 | 2017-07-11 | 10X Genomics, Inc. | Methods and systems for processing polynucleotides |
| US10584381B2 (en) | 2012-08-14 | 2020-03-10 | 10X Genomics, Inc. | Methods and systems for processing polynucleotides |
| US11591637B2 (en) | 2012-08-14 | 2023-02-28 | 10X Genomics, Inc. | Compositions and methods for sample processing |
| CA3216609C (en) | 2012-08-14 | 2024-05-14 | 10X Genomics, Inc. | Microcapsule compositions and methods |
| US10752949B2 (en) | 2012-08-14 | 2020-08-25 | 10X Genomics, Inc. | Methods and systems for processing polynucleotides |
| US10221442B2 (en) | 2012-08-14 | 2019-03-05 | 10X Genomics, Inc. | Compositions and methods for sample processing |
| US10323279B2 (en) | 2012-08-14 | 2019-06-18 | 10X Genomics, Inc. | Methods and systems for processing polynucleotides |
| US9951386B2 (en) | 2014-06-26 | 2018-04-24 | 10X Genomics, Inc. | Methods and systems for processing polynucleotides |
| US10273541B2 (en) | 2012-08-14 | 2019-04-30 | 10X Genomics, Inc. | Methods and systems for processing polynucleotides |
| WO2014093676A1 (en) | 2012-12-14 | 2014-06-19 | 10X Technologies, Inc. | Methods and systems for processing polynucleotides |
| US10533221B2 (en) | 2012-12-14 | 2020-01-14 | 10X Genomics, Inc. | Methods and systems for processing polynucleotides |
| US9411930B2 (en) * | 2013-02-01 | 2016-08-09 | The Regents Of The University Of California | Methods for genome assembly and haplotype phasing |
| AU2014214682B2 (en) | 2013-02-08 | 2018-07-26 | 10X Genomics, Inc. | Polynucleotide barcode generation |
| EP4321628B1 (en) | 2013-05-23 | 2025-09-03 | The Board of Trustees of the Leland Stanford Junior University | Transposition into native chromatin for personal epigenomics |
| WO2015157567A1 (en) | 2014-04-10 | 2015-10-15 | 10X Genomics, Inc. | Fluidic devices, systems, and methods for encapsulating and partitioning reagents, and applications of same |
| MX2016016904A (es) | 2014-06-26 | 2017-03-27 | 10X Genomics Inc | Analisis de secuencias de acidos nucleicos. |
| US12312640B2 (en) | 2014-06-26 | 2025-05-27 | 10X Genomics, Inc. | Analysis of nucleic acid sequences |
| CN113249435B (zh) | 2014-06-26 | 2024-09-03 | 10X基因组学有限公司 | 分析来自单个细胞或细胞群体的核酸的方法 |
| CA2956925C (en) | 2014-08-01 | 2024-02-13 | Dovetail Genomics, Llc | Tagging nucleic acids for sequence assembly |
| MX2017005267A (es) | 2014-10-29 | 2017-07-26 | 10X Genomics Inc | Metodos y composiciones para la secuenciacion de acidos nucleicos seleccionados como diana. |
| US9975122B2 (en) | 2014-11-05 | 2018-05-22 | 10X Genomics, Inc. | Instrument systems for integrated sample processing |
| SG11201705615UA (en) | 2015-01-12 | 2017-08-30 | 10X Genomics Inc | Processes and systems for preparing nucleic acid sequencing libraries and libraries prepared using same |
| NZ734854A (en) | 2015-02-17 | 2022-11-25 | Dovetail Genomics Llc | Nucleic acid sequence assembly |
| EP4286516A3 (en) | 2015-02-24 | 2024-03-06 | 10X Genomics, Inc. | Partition processing methods and systems |
| BR112017018054A2 (pt) | 2015-02-24 | 2018-07-24 | 10X Genomics Inc | métodos para a cobertura de sequências de ácidos nucleicos direcionadas |
| US11807896B2 (en) | 2015-03-26 | 2023-11-07 | Dovetail Genomics, Llc | Physical linkage preservation in DNA storage |
| US11802305B2 (en) * | 2015-06-24 | 2023-10-31 | Oxford BioDynamics PLC | Detection processes using sites of chromosome interaction |
| CA3002740A1 (en) | 2015-10-19 | 2017-04-27 | Dovetail Genomics, Llc | Methods for genome assembly, haplotype phasing, and target independent nucleic acid detection |
| SG11201804086VA (en) | 2015-12-04 | 2018-06-28 | 10X Genomics Inc | Methods and compositions for nucleic acid analysis |
| JP7441003B2 (ja) | 2016-02-23 | 2024-02-29 | ダブテイル ゲノミクス エルエルシー | ゲノムアセンブリのためのフェージングされたリードセットの生成とハプロタイプフェージング |
| GB201608000D0 (en) | 2016-05-06 | 2016-06-22 | Oxford Biodynamics Ltd | Chromosome detection |
| WO2017197343A2 (en) | 2016-05-12 | 2017-11-16 | 10X Genomics, Inc. | Microfluidic on-chip filters |
| WO2017197338A1 (en) | 2016-05-13 | 2017-11-16 | 10X Genomics, Inc. | Microfluidic systems and methods of use |
| WO2017197300A1 (en) | 2016-05-13 | 2017-11-16 | Dovetail Genomics Llc | Recovering long-range linkage information from preserved samples |
| MY190153A (en) * | 2016-12-01 | 2022-03-31 | Oxford BioDynamics PLC | Application of epigenetic chromosomal interactions in cancer diagnostics |
| US10815525B2 (en) | 2016-12-22 | 2020-10-27 | 10X Genomics, Inc. | Methods and systems for processing polynucleotides |
| US10550429B2 (en) | 2016-12-22 | 2020-02-04 | 10X Genomics, Inc. | Methods and systems for processing polynucleotides |
| US10011872B1 (en) | 2016-12-22 | 2018-07-03 | 10X Genomics, Inc. | Methods and systems for processing polynucleotides |
| CN110225981B (zh) * | 2016-12-23 | 2024-03-15 | 牛津生物动力有限责任公司 | 分型方法 |
| CN110214186B (zh) | 2017-01-30 | 2023-11-24 | 10X基因组学有限公司 | 用于基于微滴的单细胞条形编码的方法和系统 |
| US12264411B2 (en) | 2017-01-30 | 2025-04-01 | 10X Genomics, Inc. | Methods and systems for analysis |
| CN109526228B (zh) | 2017-05-26 | 2022-11-25 | 10X基因组学有限公司 | 转座酶可接近性染色质的单细胞分析 |
| US10844372B2 (en) | 2017-05-26 | 2020-11-24 | 10X Genomics, Inc. | Single cell analysis of transposase accessible chromatin |
| ES2987603T3 (es) | 2017-11-03 | 2024-11-15 | Oxford BioDynamics PLC | Regulación genética de la respuesta inmunitaria por interacciones cromosómicas |
| EP3954782A1 (en) | 2017-11-15 | 2022-02-16 | 10X Genomics, Inc. | Functionalized gel beads |
| US10829815B2 (en) | 2017-11-17 | 2020-11-10 | 10X Genomics, Inc. | Methods and systems for associating physical and genetic properties of biological particles |
| WO2019152543A1 (en) | 2018-01-31 | 2019-08-08 | Dovetail Genomics, Llc | Sample prep for dna linkage recovery |
| CN112004920B (zh) | 2018-02-05 | 2024-08-02 | 斯坦福大学托管董事会 | 用于单细胞和集合细胞的多重测量的系统和方法 |
| CN112262218B (zh) | 2018-04-06 | 2024-11-08 | 10X基因组学有限公司 | 用于单细胞处理中的质量控制的系统和方法 |
| CA3128973A1 (en) | 2019-03-04 | 2020-09-10 | Bhaskar Bhattacharyya | Data compression and communication using machine learning |
| AU2020381516A1 (en) * | 2019-11-15 | 2022-06-02 | Phase Genomics Inc. | Chromosome conformation capture from tissue samples |
| CN114550817B (zh) * | 2022-01-25 | 2022-12-23 | 云南大学 | 基于多特征的ctcf介导染色质环预测方法 |
| CN114841294B (zh) * | 2022-07-04 | 2022-10-28 | 杭州德适生物科技有限公司 | 一种检测染色体结构异常的分类器模型训练方法及装置 |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1428439A (zh) * | 2001-12-27 | 2003-07-09 | 赵兴波 | 利用线粒体dna指纹进行动物遗传信息鉴定的方法 |
| CN1515692A (zh) * | 2003-01-02 | 2004-07-28 | 缪金明 | “锚定点灯”式寡核苷酸芯片的检测技术 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
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| AU2002220521A1 (en) | 2000-11-29 | 2002-06-11 | Statens Seruminstitut | A screening assay for detecting chromosome rearrangements or recombinations |
| EP2295604B1 (en) | 2004-02-09 | 2015-04-08 | Thomas Jefferson University | Diagnosis and treatment of cancers with microRNA located in or near cancer-associated chromosomal features |
| US20060015264A1 (en) | 2004-06-02 | 2006-01-19 | Mcshea Andrew | Interfering stem-loop sequences and method for identifying |
| CA2614118C (en) * | 2005-07-04 | 2013-11-26 | Erasmus University Medical Center | 4c |
| GB0603251D0 (en) | 2006-02-17 | 2006-03-29 | Isis Innovation | DNA conformation |
-
2006
- 2006-02-17 GB GBGB0603251.0A patent/GB0603251D0/en not_active Ceased
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2007
- 2007-02-19 US US12/279,133 patent/US9777327B2/en active Active
- 2007-02-19 ES ES07712741T patent/ES2368767T3/es active Active
- 2007-02-19 CA CA2642331A patent/CA2642331C/en active Active
- 2007-02-19 EP EP07712741A patent/EP1991697B1/en active Active
- 2007-02-19 MY MYPI20083134A patent/MY182608A/en unknown
- 2007-02-19 NZ NZ571201A patent/NZ571201A/en unknown
- 2007-02-19 AT AT07712741T patent/ATE519864T1/de not_active IP Right Cessation
- 2007-02-19 DK DK07712741.3T patent/DK1991697T3/da active
- 2007-02-19 CN CN2007800057991A patent/CN101384734B/zh active Active
- 2007-02-19 WO PCT/GB2007/000564 patent/WO2007093819A2/en not_active Ceased
- 2007-02-19 ZA ZA200807948A patent/ZA200807948B/xx unknown
- 2007-02-19 JP JP2008554852A patent/JP5345857B2/ja active Active
- 2007-02-19 AU AU2007216315A patent/AU2007216315B2/en active Active
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2008
- 2008-09-17 NO NO20083957A patent/NO343718B1/no unknown
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2017
- 2017-08-22 US US15/683,504 patent/US11384396B2/en active Active
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1428439A (zh) * | 2001-12-27 | 2003-07-09 | 赵兴波 | 利用线粒体dna指纹进行动物遗传信息鉴定的方法 |
| CN1515692A (zh) * | 2003-01-02 | 2004-07-28 | 缪金明 | “锚定点灯”式寡核苷酸芯片的检测技术 |
Non-Patent Citations (6)
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| Blanton Jason et al,.Protein:protein interactions and the pairing of boundary elements in vivo.《GENES& DEVELOPMENT》.2003,第17卷(第5期),664-675. * |
| Byrd K, and Corces V.,.Visualization of chromatin domains created by the gypsy insulator of Drosophila.《The Journal of Cell Biology》.2003,第162卷(第4期),565-574. * |
| Dekker J, et al,.Capturing Chromosome Conformation.《Science》.2002,第295卷(第5558期),1306. * |
| Job Dekker.A closer look at long-range chromosomal interactions.《TRENDS in Biochemical Sciences》.2003,第28卷(第6期),277-280. * |
| Parnell T., et al,.An endogenous Suppressor of Hairy-wing insulator separates regulatory domains in Drosophila.《PNAS》.2003,第100卷(第23期),13436-13441. * |
| Wei Guo et al,.Mechanisms of Methotrexate Resistance in Osteosarcoma.《Clinical Cancer Research》.1999,第5卷621-627. * |
Also Published As
| Publication number | Publication date |
|---|---|
| MY182608A (en) | 2021-01-26 |
| JP2009526543A (ja) | 2009-07-23 |
| DK1991697T3 (da) | 2011-09-19 |
| HK1125416A1 (en) | 2009-08-07 |
| CA2642331A1 (en) | 2007-08-23 |
| JP5345857B2 (ja) | 2013-11-20 |
| ZA200807948B (en) | 2009-11-25 |
| AU2007216315B2 (en) | 2012-10-04 |
| CA2642331C (en) | 2018-06-19 |
| EP1991697B1 (en) | 2011-08-10 |
| ATE519864T1 (de) | 2011-08-15 |
| NO343718B1 (no) | 2019-05-20 |
| US11384396B2 (en) | 2022-07-12 |
| ES2368767T3 (es) | 2011-11-22 |
| WO2007093819A2 (en) | 2007-08-23 |
| AU2007216315A1 (en) | 2007-08-23 |
| US9777327B2 (en) | 2017-10-03 |
| US20180080081A1 (en) | 2018-03-22 |
| GB0603251D0 (en) | 2006-03-29 |
| CN101384734A (zh) | 2009-03-11 |
| EP1991697A2 (en) | 2008-11-19 |
| NO20083957L (no) | 2008-11-14 |
| US20090186352A1 (en) | 2009-07-23 |
| NZ571201A (en) | 2011-07-29 |
| WO2007093819A3 (en) | 2007-10-04 |
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