CN101379088A - 对细胞表面靶具有结合特异性的双特异性配体及其使用方法 - Google Patents

对细胞表面靶具有结合特异性的双特异性配体及其使用方法 Download PDF

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CN101379088A
CN101379088A CNA2006800523775A CN200680052377A CN101379088A CN 101379088 A CN101379088 A CN 101379088A CN A2006800523775 A CNA2006800523775 A CN A2006800523775A CN 200680052377 A CN200680052377 A CN 200680052377A CN 101379088 A CN101379088 A CN 101379088A
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dom13
dom12
dom11
dom14
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E·德安格利斯
S·霍尔姆斯
I·M·汤姆林森
E·Y·-C·黄
L·J·霍尔特
C·E·埃弗里特
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Domantis Ltd
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CNA2006800523775A 2005-12-06 2006-12-05 对细胞表面靶具有结合特异性的双特异性配体及其使用方法 Pending CN101379088A (zh)

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US74299205P 2005-12-06 2005-12-06
US60/742,992 2005-12-06

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CN101379088A true CN101379088A (zh) 2009-03-04

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CNA2006800523775A Pending CN101379088A (zh) 2005-12-06 2006-12-05 对细胞表面靶具有结合特异性的双特异性配体及其使用方法
CNA200680052392XA Pending CN101426815A (zh) 2005-12-06 2006-12-05 具有表皮生长因子受体和/或血管内皮生长因子结合特异性的配体及其使用方法

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CNA200680052392XA Pending CN101426815A (zh) 2005-12-06 2006-12-05 具有表皮生长因子受体和/或血管内皮生长因子结合特异性的配体及其使用方法

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EP (1) EP1963370A1 (enExample)
JP (1) JP2009518025A (enExample)
KR (1) KR20080090414A (enExample)
CN (2) CN101379088A (enExample)
AU (1) AU2006323415A1 (enExample)
BR (1) BRPI0619460A2 (enExample)
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US9320792B2 (en) 2002-11-08 2016-04-26 Ablynx N.V. Pulmonary administration of immunoglobulin single variable domains and constructs thereof
US20060034845A1 (en) 2002-11-08 2006-02-16 Karen Silence Single domain antibodies directed against tumor necrosis factor alpha and uses therefor
EP2238169A1 (en) 2007-12-26 2010-10-13 Biotest AG Method of decreasing cytotoxic side-effects and improving efficacy of immunoconjugates
HRP20150143T1 (hr) * 2007-12-26 2015-04-10 Biotest Ag Imunokonjugati koji ciljaju na cd138 i njihova upotreba
CN101952315B (zh) 2007-12-26 2015-04-01 生物测试股份公司 靶向cd138的试剂及其应用
KR101579218B1 (ko) 2007-12-26 2015-12-21 바이오테스트 아게 Ｃｄ138 발현성 종양 세포에 대한 표적화를 개선시키기 위한 방법 및 물질
US8574577B2 (en) 2008-01-03 2013-11-05 The Scripps Research Institute VEGF antibodies comprising modular recognition domains
US8557242B2 (en) 2008-01-03 2013-10-15 The Scripps Research Institute ERBB2 antibodies comprising modular recognition domains
US8454960B2 (en) 2008-01-03 2013-06-04 The Scripps Research Institute Multispecific antibody targeting and multivalency through modular recognition domains
CN115043946A (zh) 2008-01-03 2022-09-13 斯克里普斯研究院 通过模块识别结构域的抗体靶向
US8557243B2 (en) 2008-01-03 2013-10-15 The Scripps Research Institute EFGR antibodies comprising modular recognition domains
WO2010033249A2 (en) * 2008-09-22 2010-03-25 Massachusetts Institute Of Technology Compositions of and methods using ligand dimers
TW201019962A (en) * 2008-10-21 2010-06-01 Domantis Ltd Ligands that have binding specificity for DC-SIGN
CA2767752C (en) * 2009-02-19 2020-07-07 Elena De Angelis Improved anti-serum albumin binding variants
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US20100021473A1 (en) 2010-01-28
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