CN101366714B - 具有mGluR5拮抗活性的乙炔衍生物 - Google Patents

具有mGluR5拮抗活性的乙炔衍生物 Download PDF

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Publication number
CN101366714B
CN101366714B CN200810166366.0A CN200810166366A CN101366714B CN 101366714 B CN101366714 B CN 101366714B CN 200810166366 A CN200810166366 A CN 200810166366A CN 101366714 B CN101366714 B CN 101366714B
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hydroxyl
octahydro
ethynylene
phenylene
indole
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Chinese (zh)
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CN101366714A (zh
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F·加斯帕里尼
Y·奥贝松
S·奥夫纳
K·齐默曼
T·W·哈特
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Novartis AG
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Novartis AG
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  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Indole Compounds (AREA)
  • Quinoline Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyridine Compounds (AREA)
CN200810166366.0A 2001-12-04 2002-12-03 具有mGluR5拮抗活性的乙炔衍生物 Expired - Lifetime CN101366714B (zh)

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Application Number Priority Date Filing Date Title
GB0128996.6 2001-12-04
GBGB0128996.6A GB0128996D0 (en) 2001-12-04 2001-12-04 Organic compounds

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CN101366714A CN101366714A (zh) 2009-02-18
CN101366714B true CN101366714B (zh) 2014-09-17

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US (4) US7348353B2 (enExample)
EP (1) EP1453512B8 (enExample)
JP (2) JP4176020B2 (enExample)
KR (2) KR100980901B1 (enExample)
CN (2) CN101366714B (enExample)
AR (2) AR037682A1 (enExample)
AT (1) ATE327755T1 (enExample)
AU (1) AU2002358585B2 (enExample)
BR (1) BR0214666A (enExample)
CA (1) CA2466560C (enExample)
CO (1) CO5590929A2 (enExample)
CY (1) CY1105460T1 (enExample)
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MX (1) MXPA04005456A (enExample)
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PE (1) PE20030640A1 (enExample)
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GB0508319D0 (en) * 2005-04-25 2005-06-01 Novartis Ag Organic compounds
GB0508314D0 (en) * 2005-04-25 2005-06-01 Novartis Ag Organic compounds
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EP2826478A1 (en) * 2008-06-30 2015-01-21 Novartis AG Combinations comprising mglur modulators for the treatment of parkinson's disease
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BR112012027816A2 (pt) * 2010-04-30 2017-08-08 Novartis Ag marcadores preditivos úteis no tratamento da síndrome do x frágil (fxs).
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CA3066711A1 (en) 2017-07-31 2019-02-07 Novartis Ag Use of mavoglurant in the reduction of cocaine use or in preventing relapse into cocaine use
US12201612B2 (en) 2017-07-31 2025-01-21 Novartis Ag Use of mavoglurant in the reduction of alcohol use or in preventing relapse into alcohol use
KR20210120011A (ko) 2019-01-29 2021-10-06 노파르티스 아게 오피오이드 진통제 내약성을 치료하기 위한 mglur5 길항제의 용도
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MX2023000664A (es) 2020-07-17 2023-02-27 Novartis Ag Uso de antagonistas de mglur5.
WO2022123482A1 (en) 2020-12-11 2022-06-16 Novartis Ag Use of mglur5 antagonists for treating amphetamine addiction
CA3204360A1 (en) 2020-12-14 2022-06-23 Novartis Ag Use of mglur5 antagonists for treating gambling disorder

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