CN101355925A - Cosmetic composition containing algae extract for effect on improving the skin complexion - Google Patents

Cosmetic composition containing algae extract for effect on improving the skin complexion Download PDF

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CN101355925A
CN101355925A CNA2006800503818A CN200680050381A CN101355925A CN 101355925 A CN101355925 A CN 101355925A CN A2006800503818 A CNA2006800503818 A CN A2006800503818A CN 200680050381 A CN200680050381 A CN 200680050381A CN 101355925 A CN101355925 A CN 101355925A
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skin
extract
composition
dunaliella salina
cosmetic composition
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朴城逸
朴昶埙
韩相勋
姜鹤熙
郑惠珍
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Amorepacific Corp
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/08Anti-ageing preparations
    • EFIXED CONSTRUCTIONS
    • E04BUILDING
    • E04FFINISHING WORK ON BUILDINGS, e.g. STAIRS, FLOORS
    • E04F15/00Flooring
    • E04F15/18Separately-laid insulating layers; Other additional insulating measures; Floating floors
    • E04F15/20Separately-laid insulating layers; Other additional insulating measures; Floating floors for sound insulation
    • E04F15/206Layered panels for sound insulation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9706Algae
    • A61K8/9722Chlorophycota or Chlorophyta [green algae], e.g. Chlorella
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • EFIXED CONSTRUCTIONS
    • E04BUILDING
    • E04BGENERAL BUILDING CONSTRUCTIONS; WALLS, e.g. PARTITIONS; ROOFS; FLOORS; CEILINGS; INSULATION OR OTHER PROTECTION OF BUILDINGS
    • E04B1/00Constructions in general; Structures which are not restricted either to walls, e.g. partitions, or floors or ceilings or roofs
    • E04B1/62Insulation or other protection; Elements or use of specified material therefor
    • E04B1/74Heat, sound or noise insulation, absorption, or reflection; Other building methods affording favourable thermal or acoustical conditions, e.g. accumulating of heat within walls
    • E04B1/88Insulating elements for both heat and sound
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q1/00Make-up preparations; Body powders; Preparations for removing make-up
    • A61Q1/02Preparations containing skin colorants, e.g. pigments
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q1/00Make-up preparations; Body powders; Preparations for removing make-up
    • A61Q1/02Preparations containing skin colorants, e.g. pigments
    • A61Q1/04Preparations containing skin colorants, e.g. pigments for lips
    • A61Q1/06Lipsticks

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Abstract

The present invention relates to a cosmetic composition for improving skin complexion comprising an alga extract. More particularly, the cosmetic composition according to the present invention comprises an extract from the alga Dunaliella Salina to provide energy to skin cells and promotes turn-over of epidermal cells, thereby providing skin complexion and clearness improving effect on the aged skin or darkened skin caused by outer circumstance and stress.

Description

Be used to improve the cosmetic composition that contains algae extract of skin complexion
Technical field
The present invention relates to a kind of cosmetic composition that is used to improve skin complexion, said composition contains algae extract.More specifically, cosmetic composition of the present invention contains the extract of Dunaliella salina algae, for Skin Cell provides energy, promote the regeneration (turn-over) of epidermis cell, thereby provide the effect that improves skin complexion and cleaning for the aged skin that causes by external environment or stress or the skin of deepening.
Background technology
Usually, cosmetics are in order to clean health, to make the ground of oneself dressing up so beautiful that it excites men and protection skin and hair not be subjected to ultraviolet and exsiccant the influence, thereby prevent to wear out.Recently, because the development of industrial society and the increase of social activity, actively express own self consciousness thereby be improved, so greatly increased the needs of apply some make up maintenance and maintenance skin.Therefore, researched and developed the basic cosmetics product of different cultivars and dosage form.Wherein, the cosmetic product that makes dim skin become light is regarded as the product very important to the user.
Skin is divided into such three layers of epidermis, corium and subcutaneus adipose tissue from skin, has played to prevent that health is subjected to the physics of external environment and the effect of chemical stimulation.Especially, epidermis is divided into horny layer, granular layer, spinous layer and basal layer from skin.The basal layer of epidermis cell in the bottom that constitutes skin generates, and is grown to horny layer, and becomes aged keratose, and aged then keratose comes off, thereby always keeps new skin surface.In the adolescence of health, such skin growth circulation probably needs 28 days.Along with people's age change is big, because the active decline of energy metabolism of stress and Skin Cell, skin has lost its original activity level.By these effects, and since the stress that comes from the outside, the mitochondrial hypofunction of skin, and the activity of skin has reduced.And, because can not provide enough nutrition, reduced the regeneration of Skin Cell by blood.As a result, formed fine wrinkle, and face seems dimness and sallow.Simultaneously, child's the skin growth cycle have an appointment 10 days so short, therefore, they have smooth and clean skin.So it is to remove aged keratinized skin that ideal skin is regulated, and promote skin growth.Usually, many exfoliation products and skin massaging paster are to be used for removing aged keratinized skin.But if remove cornified skin with non-natural physics and chemical method, skin can come to harm and can promote the aging of skin.Therefore, preferably promote skin growth preventing the accumulation of cornified skin, and the Skin Cell of living is not damaged.
Therefore, developed the regeneration that the various raw materials that are used for cosmetics promote Skin Cell.But because consumer loses interest and bovine spongiform encephalopathy popular gradually to animal material, the use of animal material reduces rapidly, and becomes focus by the natural material that plant is got.Along with this trend, in synthesizing of energy metabolism that promotes Skin Cell and adenosine triphosphate (ATP) so that under Skin Cell activation and the regenerated theory, used the raw material of various plant extracts, yeast extract and mineralogical composition.But their effect is not confirmed.Therefore, be badly in need of developing a kind of cosmetic composition that improves the remarkable result of the colour of skin by the activation Skin Cell that has.
Summary of the invention
Therefore, the present inventor studies the natural extract with the remarkable result that improves the colour of skin, the final Dunaliella salina (Dunaliella Salina) that is at least spontaneous growth in 30% the salina in salinity of finding has very strong survival ability, can be for skin provide energy, thus the growth of Skin Cell promoted.Based on this discovery, finished the present invention.
Therefore, an object of the present invention is to provide a kind of cosmetic composition that is used to improve skin complexion that contains the extract of Dunaliella salina.
In order to achieve the above object, the invention provides a kind of cosmetic composition that is used to improve skin complexion that contains the extract of Dunaliella salina.
Below, will be described in detail the present invention.
The preparation of the algae extract that the present invention uses comprises: carry out special fermentation process by using bioreactor, the Dunaliella salina microalgae is cultivated; Extract then.In experiment of the present invention, used the bio-dusali (Bio-Dusali) that provides by Switzerland Pan Defa company (Pentapharm).Dunaliella salina is that a kind of salinity that is grown in is at least halophilic bacteria in 30% the salina, belongs to the salt alga kind that Chlorophyceae (Chlorophyceae class) volvocales (Chlamydomonadales order) Dunaliella salina section (Dunaliellaceae family) Dunaliella salina belongs to (Dunaliella genus).It can expose survival under extreme environment, for example, and hyperosmosis, elevated oxygen level and high ultraviolet radiation.This algae is for the living necessities lot of energy, and these energy are obtained by photosynthesis.This Johnson ﹠ Johnson of Dunaliella salina deposits ability and energy-producing ability can act on skin, required power is provided and new energy is provided to Skin Cell.And the extract of this algae contains each seed amino acid and bicarbonate, and with to the skin makeup energy, protection also stimulates mitochondrion as the Skin Cell center of energy, thereby promotes that ATP is synthetic and provide energy to skin.When containing this algae extract in the cosmetic composition, the energy-producing ability of this algae extract can promote the regeneration of Skin Cell, thereby makes skin seem totally penetrating, and healthy.
In cosmetic composition of the present invention, be benchmark with the gross weight of compositions, the content of this algae extract is 0.01-30.0 weight %, is preferably 0.1-10.0 weight %.When content during, be difficult to reach ideal effect less than 0.01 weight %.When content surpasses 30.0 weight %, be difficult to the viscosity of control cosmetics goods, and economic benefit is low, therefore, is difficult to be developed as cosmetic product.
The cosmetic composition of use algae extract of the present invention can be used to improve the cosmetic product of skin complexion.There is no particular limitation to dosage form, for example, can comprise toner/smoothing toner, skin cream, massage cream, moisturizer, facial film, gel, essence, lip pomade, cosmetic base material, foundation cream, dew, ointment, gel, facial cream, paster or spray.
Description of drawings
Below, the detailed description that the present invention is carried out can be understood further purpose of the present invention and advantage more fully in conjunction with the drawings.
Fig. 1 is the questionnaire result to the definition of penetrating skin (transparent skin);
Fig. 2 is the skin test system (VISIA-CR) that is used to measure skin Lightening;
Fig. 3 is for using embodiments of the invention 1 and 2 and the curve chart that changes of the skin Lightening degree of Comparative Examples 1;
Fig. 4 is for using embodiments of the invention 1 and 2 and the curve chart that changes of the skin moisture content of Comparative Examples 1;
Fig. 5 is for using embodiments of the invention 1 and 2 and the curve chart that changes of the skin uniformity of Comparative Examples 1;
Fig. 6 is for using embodiments of the invention 1 and 2 and the curve chart of the keratic quantitative changeization of Comparative Examples 1;
The specific embodiment
Below, the present invention will be described in detail by following examples and test implementation example.But, it should be understood that the present invention is not limited to this.
Questionnaire
Please 30 Korea S adult females (30-49 year) answer a questionnaire, so that penetrating skin is defined.The results are shown in Fig. 1.
As shown in Figure 1, the respondent to the answer of penetrating skin is successively: the colour of skin of light, and moistening skin, slick skin, the skin with even colour of skin has a small amount of keratic skin.Therefore, for above-mentioned aspect, carried out the described process of following test implementation example, to determine the effect of improving of skin complexion.
Embodiment 1-2 and Comparative Examples 1
With preparing embodiment 1-2 and Comparative Examples 1, change the content of bio-dusali extract as following table 1 described composition.Following preparation is dissolved skin preparation, and wherein, the unit of content is: weight %.
Table 1
Figure A20068005038100071
Embodiment 1 and 2 and the preparation of Comparative Examples 1
(1) at room temperature, water composition is dissolved equably and mix.
(2) at room temperature, pure composition is dissolved equably and mix.
(3) at room temperature, while stirring (2) are joined in (1) lentamente, make dissolved skin preparation.
Test implementation example 1: the effect that strengthens skin Lightening
The face that the skin preparation that will have a composition of embodiment 1-2 and Comparative Examples 1 is applied to 30 Korea S adult females (30-49 year) used for four weeks every day twice, measured the variation of skin Lightening degree.Measure the brightness of skin with skin test system (VISIA-CR) (referring to Fig. 2).Skin test system (VISIA-CR) is used for the brightness of evaluating skin.Detect measured's same area when 0 week, 1 week, 2 weeks and 4 weeks with VISIA-CR.The test position is whole face, face is taken pictures, and analyze with professional image analysis software (Image-pro plus software) (5.01 version).Comprise with VISIA-CR test face is placed on forehead holder and the chin pocket, and face is taken pictures with the photographing unit of installing in the machine.Determine the skin Lightening degree by measuring face, wherein, the bright more then value of skin is high more, and the dim more then value of skin is low more.Result such as table 2 and shown in Figure 3.
Table 2: skin Lightening degree
Figure A20068005038100081
Find out that from the result of table 2 and Fig. 3 the skin Lightening degree significantly increases among the embodiment 1-2 of use " bio-dusali ".And when the content of bio-dusali increased, the brightness increase was more.Under the situation of embodiment 1 and 2, to compare with 0 week, the value that 1,2 and 4 weeks measured has increased, and the increase of skin Lightening degree has significance,statistical (p<0.05) after 4 weeks.
Test implementation example 2: the effect that skin moisture content increases
The face that the skin preparation that will have a composition of embodiment 1-2 and Comparative Examples 1 is applied to 30 Korea S adult females (30-49 year) used for four weeks every day twice, measured the variation of skin moisture content.Skin moisture content is measured with moisture tester (corneometer).
In the room that enters the control temperature and humidity, after 30 minutes, use moisture tester (CM825Courage﹠amp; Khazaka, Germany) measure measured's buccal and lower limb 5 times, remove maximum and minima, write down the meansigma methods of all the other 3 values.When skin moisture content increased, this was worth increase; When skin moisture content reduced, this was worth reduction.Result such as table 3 and shown in Figure 4.
Table 3 skin moisture content
Figure A20068005038100091
Find out that from the result of table 3 and Fig. 4 compare with Comparative Examples 1, embodiment 1-2 shows rolling up of skin moisture content, and when the content of bio-dusali extract increased, skin moisture content increased significantly.And though recruitment has reduced after 2 weeks, along with the prolongation of service time, moisture has increased.
Test implementation example 3: improve the inhomogeneity effect of skin
For the skin preparation of determining embodiment 1-2 that contains bio-dusali of the present invention and Comparative Examples 1 improve the inhomogeneity effect of skin, measure the inhomogeneity improvement of skin by the deviation of the value that records with VISIA-CR in the test implementation example 1.
The face that the skin preparation that will have a composition of embodiment 1-2 and Comparative Examples 1 is applied to 30 Korea S adult females (30-49 year) used for four weeks every day twice, measured the inhomogeneity variation of skin.When 0 week, 1 week, 2 weeks and 4 weeks, detect measured's same area with VISIA-CR.The test position is whole face, face is taken pictures, and analyze with professional image analysis software (5.01 version).Comprise with VISIA-CR test face is placed on forehead holder and the chin pocket, and face is taken pictures with the photographing unit of installing in the machine.Deviation by different all faces of measuring is determined the skin uniformity.When the skin good uniformity, then should value reduce, and when the skin lack of homogeneity, then should value increase.Result such as table 4 and shown in Figure 5.
Fig. 4: skin uniformity
Find out from the result of table 4 and Fig. 5, compare, use the embodiment 1-2 of bio-dusali extract to show the inhomogeneity very big improvement of skin with Comparative Examples 1.Under the situation of embodiment 1-2, compare with 0 week, have significance,statistical (p<0.05) in the reduction of the deviations of measuring in 4 weeks, and the reduction of embodiment 2 is bigger.Therefore, can determine that bio-dusali can improve the skin uniformity effectively.
Test implementation example 4: the reduction of keratic amount
The skin preparation that will have the composition of embodiment 1-2 and Comparative Examples 1 is applied to 30 Korea S adult females face in (30-49 year), uses for four weeks every day twice, detects the variation of keratic amount.Peel off band acquisition angle protein sample by use and measure, peel off rate with measurement with D-Squame acquisition angle protein sample.Measure portion is divided into the right and the left side.The left side (the right) part is sampled with D-Squame, and the right (left side) part is sampled with the Black adhesive tape.With sample collection D-Squame standard storing card (D-Squame Standard Storage Cards) (CUDERM, USA) in.
With the Hi-scope (Hirox that is connected with computer, Japan) and Charmview (Moritex, Japan) to taking pictures with the enlargement ratio of 40 times and 700 times with the keratin of D-Squame and Black adhesive tape sampling, and be converted to bitmap (bitmap image), use this bitmap and use BMI image analysis software (WINaTech, USA) area (pixel count) of the cornified skin of calculating.Use paired t-check (SPSS version 10),, 1 week preceding to using, 2 weeks and the results that measured in 4 weeks analyze and compare.Result such as table 5 and shown in Figure 6.
Fig. 5: the variation of keratic amount
Figure A20068005038100111
Find out from the result of table 5 and Fig. 6, compare, use the embodiment 1 and 2 of bio-dusali extract on the keratic amount of minimizing, to show better effect with Comparative Examples 1.Under the situation of embodiment 1-2, compare with 0 week, used for 4 weeks after, the minimizing of keratic amount has significance,statistical (p<0.05), and embodiment 2 reduces manyly.This shows that the Dunaliella salina extract can reduce keratic amount effectively.
Test implementation example 5
In order to confirm the improve effect of cosmetic composition of the present invention to skin complexion, the skin preparation that will have the composition of embodiment 1-2 is applied to 20 Korea S adult females (30-49 year) (embodiment 1:10 people, embodiment 2:10 people) face, every day twice is around using.Please the tester answer use these skin preparations after skin whether become smooth penetrating.The result is shown in table 6 and table 7.
Table 6: skin smoothness evaluation
Figure A20068005038100112
Table 7: the improvement of skin complexion
Figure A20068005038100121
As shown in table 6, after two weeks, all testers reflect that skin becomes smooth.Can confirm that by these results the Dunaliella salina extract has the effect of improving skin smoothness.
And as shown in table 7, in 2 whens week, 90% tester feels that skin becomes penetrating, and to around the time, all testers feel that all skin becomes penetrating.Can confirm that by these results Dunaliella salina extract of the present invention can improve skin complexion as it is considered to ground.
As mentioned above, the invention relates to a kind of cosmetic composition that contains algae extract that is used to improve skin complexion.Occurred many be intended to make skin flexible saturating clean conventional ingredient and products in the market, do not obtained clear and definite approval but their problem is effect.According to the present invention, it is of great value setting up the skin complexion evaluation system, and uses this system, has developed the cosmetic composition that can effectively improve skin complexion.Cosmetic composition of the present invention can increase skin Lightening degree and skin moisture content effectively, improves the skin uniformity, reduces the amount of skin keratin and improves skin smoothness, and thereby improve skin complexion.And said composition can be mixed with the cosmetic product that is used to improve skin complexion, and after using for 4 weeks at least, its effect can get the nod.

Claims (8)

1, a kind of cosmetic composition that is used to improve skin complexion, said composition contains the extract of Dunaliella salina algae.
2, compositions according to claim 1, said composition promotes the regeneration of epidermis cell and reduces keratic amount.
3, a kind of cosmetic composition that is used to make skin moisture-keeping, said composition contains the extract of Dunaliella salina.
4, a kind ofly be used to improve the inhomogeneity cosmetic composition of skin, said composition contains the extract of Dunaliella salina.
5, a kind of cosmetic composition that is used to improve skin smoothness, said composition contains the extract of Dunaliella salina.
6, according to any described compositions among the claim 1-5, wherein, described algae is to belong to the salt alga kind that Chlorophyceae volvocales Dunaliella salina section Dunaliella salina belongs to.
7, according to any described compositions among the claim 1-5, be benchmark with the gross weight of said composition, the content of algae extract is 0.01-30.0 weight %.
8, according to any described compositions among the claim 1-5, said composition is formulated into toner/smoothing toner, skin cream, massage cream, moisturizer, facial film, gel, essence, lip pomade, cosmetic base material, foundation cream, dew, ointment, gel, facial cream, paster or spray.
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CN104771352A (en) * 2015-04-27 2015-07-15 广州源大生物科技有限公司 Air cushion BB cream and preparation method thereof
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