CN101347572A - Medicament for treating diabetes and preparation method - Google Patents
Medicament for treating diabetes and preparation method Download PDFInfo
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- CN101347572A CN101347572A CNA2008101512196A CN200810151219A CN101347572A CN 101347572 A CN101347572 A CN 101347572A CN A2008101512196 A CNA2008101512196 A CN A2008101512196A CN 200810151219 A CN200810151219 A CN 200810151219A CN 101347572 A CN101347572 A CN 101347572A
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Abstract
The invention discloses a medicine for treating diabetes and a preparation method thereof. The preparation method comprises the following steps: (1) day lily and dry walnut branches are weighted; (2) water is added in the day lily, and the mixture is boiled by sharp fire for 5-10 minutes and is soaked for 6-10 hours; then, the mixture is treated with solid-liquid separation, the boiled and soaked day lily is pulverized into powder for spare use after being baked by tile to form coke, and separated liquid is for spare use; (3) the mixed liquid of white spirit and white vinegar is added in the dry walnut branches for soaking the dry walnut branches for 1-3 hours, and the mixture is treated with solid-liquid separation; the soaked dry walnut branches are dried in the shade, waters with 1-5 times the weight of the shade drying dry walnut branches is added in the dry walnut branches; the mixture is boiled by soft fire for 20-30 minutes and is soaked for 10-12 hours; then, the mixture is treated with solid-liquid separation, and separated liquid is for spare use; (4) the liquid prepared in step (2), the liquid prepared in step (3) and powder prepared in step (3) are uniformly mixed, thus the medicine for treating diabetes is prepared. The medicine of the medicine has the advantages that: raw materials are cheap and easily-obtained; curative effect on lowering blood sugar is obvious; patients can not feel unwell after administration.
Description
Technical field
The present invention relates to a kind of Chinese medicine preparation and preparation method, particularly relate to a kind of treatment diabetes medicament and preparation method.
Background technology
Along with improving constantly of people's living standard, to increase year by year as the onset diabetes rate of one of affluenza, it not only causes very big injury to patient's body, also because the expenditure increase of expenses for medicine increases the weight of the patient burden.Often use the oral antidiabetic drug of chemosynthesis clinically, they are the concentration of blood sugar control well, delay increasing the weight of of disease, particularly at type ii diabetes, better effects if, but oral antidiabetic drug more or less has certain toxic and side effects, and particularly some medicine exerts an adverse impact to the function of liver, kidney, therefore, limited some patient's use.
Summary of the invention
The objective of the invention is to overcome deficiency of the prior art, provide a kind of and have no side effect, treatment diabetes medicament evident in efficacy.
Second purpose of the present invention provides a kind of preparation method for the treatment of diabetes medicament.
Technical scheme of the present invention is summarized as follows:
A kind of treatment diabetes medicament, make with following method:
(1) take by weighing by mass percentage: Radix hemerocalis plicatae 60%-80%, Semen Juglandis do branch 20%-40%;
(2) in described Radix hemerocalis plicatae, add 1-5 quality water doubly, very hot oven boiled 5-10 minute, soaked 6-10 hour, and solid-liquid separation will be boiled the Radix hemerocalis plicatae of steeping with after watt baking burnt shape, and it is standby to pulverize powdered, and the liquid after the separation is standby;
(3) described Semen Juglandis is done branch and added 1-5 quality Chinese liquor white vinegar mixed liquid dipping doubly 1-3 hour, solid-liquid separation, the Ramulus Juglandis that soaked is dried in the shade, after adding the Ramulus Juglandis 1-5 quality water boil doubly after described the drying in the shade, change warm fire and boiled 20-30 minute, soaked solid-liquid separation 10-12 hour, liquid after the separation is standby, and the percent by volume of Chinese liquor is 40%-60% in the described Chinese liquor white vinegar mixed liquor;
(4) powder mixes of the liquid of the liquid that described step (2) is prepared, described step (3) preparation and described step (2) preparation is even, promptly makes a kind of medicine for the treatment of diabetes.
Preferably, Radix hemerocalis plicatae is 70%, and it is 30% that Semen Juglandis is done branch.
Step (2) is preferably: in described Radix hemerocalis plicatae, add 3 quality water doubly, very hot oven boiled 8 minutes, soaked 8 hours, and solid-liquid separation will be boiled the Radix hemerocalis plicatae of steeping with after watt baking burnt shape, and it is standby to pulverize powdered, and the liquid after the separation is standby.
Described step (3) is preferably: described Semen Juglandis is done branch add 3 quality Chinese liquor white vinegar mixed liquid dipping doubly 2 hours, solid-liquid separation, the Ramulus Juglandis that soaked is dried in the shade, after adding the Ramulus Juglandis 3 quality water boil doubly after described the drying in the shade, change warm fire and boiled 25 minutes, soaked solid-liquid separation 11 hours, liquid after the separation is standby, and the percent by volume of Chinese liquor is 50% in the described Chinese liquor white vinegar mixed liquor.
A kind of preparation method for the treatment of diabetes medicament, form by following steps:
(1) take by weighing by mass percentage: Radix hemerocalis plicatae 60%-80%, Semen Juglandis do branch 20%-40%;
(2) in described Radix hemerocalis plicatae, add 1-5 quality water doubly, very hot oven boiled 5-10 minute, soaked 6-10 hour, and solid-liquid separation will be boiled the Radix hemerocalis plicatae of steeping with after watt baking burnt shape, and it is standby to pulverize powdered, and the liquid after the separation is standby;
(3) described Semen Juglandis is done branch and added 1-5 quality Chinese liquor white vinegar mixed liquid dipping doubly 1-3 hour, solid-liquid separation, the Ramulus Juglandis that soaked is dried in the shade, after adding the Ramulus Juglandis 1-5 quality water boil doubly after described the drying in the shade, change warm fire and boiled 20-30 minute, soaked solid-liquid separation 10-12 hour, liquid after the separation is standby, and the percent by volume of Chinese liquor is 40%-60% in the described Chinese liquor white vinegar mixed liquor;
(4) powder mixes of the liquid of the liquid that described step (2) is prepared, described step (3) preparation and described step (2) preparation is even, promptly makes a kind of medicine for the treatment of diabetes.
Preferably, Radix hemerocalis plicatae is 70%, and it is 30% that Semen Juglandis is done branch.
Step (2) is preferably: in described Radix hemerocalis plicatae, add 3 quality water doubly, very hot oven boiled 8 minutes, soaked 8 hours, and solid-liquid separation will be boiled the Radix hemerocalis plicatae of steeping with after watt baking burnt shape, and it is standby to pulverize powdered, and the liquid after the separation is standby.
Described step (3) is preferably: described Semen Juglandis is done branch add 3 quality Chinese liquor white vinegar mixed liquid dipping doubly 2 hours, solid-liquid separation, the Ramulus Juglandis that soaked is dried in the shade, after adding the Ramulus Juglandis 3 quality water boil doubly after described the drying in the shade, change warm fire and boiled 25 minutes, soaked solid-liquid separation 11 hours, liquid after the separation is standby, and the percent by volume of Chinese liquor is 50% in the described Chinese liquor white vinegar mixed liquor.
A kind of treatment diabetes medicament of the present invention is a plant extract, select for use and have logical knot, the Radix hemerocalis plicatae of the long-pending stasis of blood of dispelling and the Semen Juglandis with the ruton muscle arteries and veins effect of stimulating the menstrual flow are done branch and are feedstock production, in use; get that medicine of the present invention adds that an amount of Semen Tritici aestivi flour stirs and and becomes soft dough after; make diameter and be about 5-9cm; thickness is about the circular or oval-shaped little medicine cake of 2-5mm; the deposited specified meridians of the medical professional district that is placed on; add certain temperature (the glass cupping jar of use certain specification); through medication after a while, can produce hypoglycemic effect, raw material of the present invention cheaply is easy to get; blood sugar lowering is evident in efficacy, and the patient does not have uncomfortable symptom.
The specific embodiment
The present invention is further illustrated below in conjunction with specific embodiment.
Embodiment 1
A kind of treatment diabetes medicament, make with following method:
(1) take by weighing by mass percentage: Radix hemerocalis plicatae 70g, Semen Juglandis do branch 30g;
(2) in Radix hemerocalis plicatae, add 210g water, very hot oven boiled 8 minutes, soaked 8 hours, and solid-liquid separation will be boiled the Radix hemerocalis plicatae of steeping with after watt baking burnt shape, and it is standby to pulverize powdered, and the liquid after the separation is standby;
(3) Semen Juglandis being done a Chinese liquor white vinegar mixed liquor (volume ratio of Chinese liquor and white vinegar is 1: 1 in the mixed liquor) that adds 90g soaked 2 hours, solid-liquid separation, the Ramulus Juglandis that soaked is dried in the shade, after adding the Ramulus Juglandis 3 quality water boil doubly after drying in the shade, changing warm fire boiled 25 minutes, soaked 11 hours, solid-liquid separation, the liquid after the separation is standby;
(4) powder mixes of the liquid of the liquid that step (2) is prepared, step (3) preparation and step (2) preparation is even, promptly makes a kind of medicine for the treatment of diabetes.
Embodiment 2
A kind of treatment diabetes medicament, make with following method:
(1) take by weighing by mass percentage: Radix hemerocalis plicatae 60g, Semen Juglandis do branch 40g;
(2) in Radix hemerocalis plicatae, add 60g water, very hot oven boiled 5 minutes, soaked 10 hours, and solid-liquid separation will be boiled the Radix hemerocalis plicatae of steeping with after watt baking burnt shape, and it is standby to pulverize powdered, and the liquid after the separation is standby;
(3) described Semen Juglandis is done the Chinese liquor white vinegar mixed liquid dipping 3 hours (volume ratio of Chinese liquor and white vinegar is 40: 60 in the mixed liquor) that branch adds 40g, solid-liquid separation, the Ramulus Juglandis that soaked is dried in the shade, after adding the Ramulus Juglandis 5 quality water boil doubly after drying in the shade, changing warm fire boiled 30 minutes, soaked 10 hours, solid-liquid separation, the liquid after the separation is standby;
(4) powder mixes of the liquid of the liquid that described step (2) is prepared, described step (3) preparation and described step (2) preparation is even, promptly makes a kind of medicine for the treatment of diabetes.
Embodiment 3
A kind of treatment diabetes medicament, make with following method:
(1) take by weighing by mass percentage: Radix hemerocalis plicatae 80g, Semen Juglandis do branch 20g;
(2) in described Radix hemerocalis plicatae, add 160g water, very hot oven boiled 7 minutes, soaked 9 hours, and solid-liquid separation will be boiled the Radix hemerocalis plicatae of steeping with after watt baking burnt shape, and it is standby to pulverize powdered, and the liquid after the separation is standby;
(3) described Semen Juglandis is done the Chinese liquor white vinegar mixed liquid dipping 1 hour (volume ratio of Chinese liquor and white vinegar is 60: 40 in the mixed liquor) that branch adds 100g, solid-liquid separation, the Ramulus Juglandis that soaked is dried in the shade, after adding the Ramulus Juglandis 1 quality water boil doubly after drying in the shade, changing warm fire boiled 20 minutes, soaked 12 hours, solid-liquid separation, the liquid after the separation is standby;
(4) powder mixes of the liquid of the liquid that described step (2) is prepared, described step (3) preparation and described step (2) preparation is even, promptly makes a kind of medicine for the treatment of diabetes.
Embodiment 4
A kind of treatment diabetes medicament, make with following method:
(1) take by weighing by mass percentage: Radix hemerocalis plicatae 65g, Semen Juglandis do branch 35g;
(2) in described Radix hemerocalis plicatae, add 325g water, very hot oven boiled 10 minutes, soaked 6 hours, and solid-liquid separation will be boiled the Radix hemerocalis plicatae of steeping with after watt baking burnt shape, and it is standby to pulverize powdered, and the liquid after the separation is standby;
(3) described Semen Juglandis is done the Chinese liquor white vinegar mixed liquid dipping 2 hours (volume ratio of Chinese liquor and white vinegar is 1: 1 in the mixed liquor) that branch adds 140g, solid-liquid separation, the Ramulus Juglandis that soaked is dried in the shade, after adding the Ramulus Juglandis 4 quality water boil doubly after drying in the shade, changing warm fire boiled 23 minutes, soaked 11 hours, solid-liquid separation, the liquid after the separation is standby;
(4) powder mixes of the liquid of the liquid that described step (2) is prepared, described step (3) preparation and described step (2) preparation is even, promptly makes a kind of medicine for the treatment of diabetes.
The selected Radix hemerocalis plicatae of various embodiments of the present invention is to dry or the petal of the Radix hemerocalis plicatae of drying.
The present invention's selected container or heater in preparation process avoided the pure iron device.
Therapeutic effect:
Diabetics 30 people, wherein, male 14 people, women 16 people, the age, between year, symptom was slight at 42-57, and fasting glucose is lower than light-duty patient 21 people of 11.1mmol/L, and symptom is more obvious, and fasting glucose is medium-sized patient 9 people of 11.1mmol/L-16.7mmol/L.
In use, get medicine of the present invention and add that an amount of Semen Tritici aestivi flour stirs and, make diameter and be about 5-9cm that thickness is about circle or the oval-shaped little medicine cake of 2-5mm, the deposited specified meridians of the medical professional district that is placed on hands with after becoming soft dough.Paste once every day, pastes 15-20min, adding certain temperature, pasted 3-15 days, detects fasting glucose, and the collection data are as follows:
| Patient's sum | Produce effects | Effectively | Invalid |
| Light-duty patient 21 people | 15 | 6 | 0 |
| Medium-sized patient 9 people | 6 | 2 | 1 |
Produce effects: refer to that blood glucose target reduces to normally;
Effectively: refer to that blood glucose target descends to some extent;
Invalid: as to refer to that blood glucose target has fluctuation, has bounce-back.
Total effective rate=96.7%.
Below be the treatment example
Song, because of diabetes were lived institute, the about 9mmol/L of blood glucose before the meal, the about 18mmol/L of post-prandial glycemia uses a kind of treatment diabetes medicament of the present invention 15 times, and over the past half year, blood glucose target reaches normally, no longer takes medicine.
Chen, the about 8mmol/L of blood glucose before the meal, the about 10mmol/L of post-prandial glycemia uses a kind of treatment diabetes medicament of the present invention 9 times, and blood glucose target reaches normally, has refused to obey oral antidiabetic drug.
Zhang, the about 9mmol/L of blood glucose is before the meal found in health check-up, and the about 20mmol/L of post-prandial glycemia uses a kind of treatment diabetes medicament of the present invention 10 times, and blood glucose target reaches normally, has now refused to obey oral antidiabetic drug.
The Yin Dynasty so-and-so, the about 8mmol/L of blood glucose before the meal, the about 9mmol/L of post-prandial glycemia uses a kind of treatment diabetes medicament of the present invention 6 times, it is normal that blood glucose target reaches.
Raw material of the present invention cheaply is easy to get, and blood sugar lowering is evident in efficacy, and the patient does not have uncomfortable disease.
Claims (8)
1. treat diabetes medicament for one kind, it is characterized in that making with following method:
(1) take by weighing by mass percentage: Radix hemerocalis plicatae 60%-80%, Semen Juglandis do branch 20%-40%;
(2) in described Radix hemerocalis plicatae, add 1-5 quality water doubly, very hot oven boiled 5-10 minute, soaked 6-10 hour, and solid-liquid separation will be boiled the Radix hemerocalis plicatae of steeping with after watt baking burnt shape, and it is standby to pulverize powdered, and the liquid after the separation is standby;
(3) described Semen Juglandis is done branch and added 1-5 quality Chinese liquor white vinegar mixed liquid dipping doubly 1-3 hour, solid-liquid separation, the Ramulus Juglandis that soaked is dried in the shade, after adding the Ramulus Juglandis 1-5 quality water boil doubly after described the drying in the shade, change warm fire and boiled 20-30 minute, soaked solid-liquid separation 10-12 hour, liquid after the separation is standby, and the percent by volume of Chinese liquor is 40%-60% in the described Chinese liquor white vinegar mixed liquor;
(4) powder mixes of the liquid of the liquid that described step (2) is prepared, described step (3) preparation and described step (2) preparation is even, promptly makes a kind of medicine for the treatment of diabetes.
2. a kind of treatment diabetes medicament according to claim 1 is characterized in that described Radix hemerocalis plicatae is 70%, and it is 30% that Semen Juglandis is done branch.
3. a kind of treatment diabetes medicament according to claim 1, it is characterized in that described step (2) is: in described Radix hemerocalis plicatae, add 3 quality water doubly, very hot oven boiled 8 minutes, soaked 8 hours, solid-liquid separation will be boiled the Radix hemerocalis plicatae of steeping with after watt baking burnt shape, it is standby to pulverize powdered, and the liquid after the separation is standby.
4. a kind of treatment diabetes medicament according to claim 1, it is characterized in that described step (3) is: described Semen Juglandis is done branch add 3 quality Chinese liquor white vinegar mixed liquid dipping doubly 2 hours, solid-liquid separation, the Ramulus Juglandis that soaked is dried in the shade, add the Ramulus Juglandis 3 quality water boil doubly after described the drying in the shade after, change warm fire and boiled 25 minutes, soaked 11 hours, solid-liquid separation, the liquid after the separation is standby, and the percent by volume of Chinese liquor is 50% in the described Chinese liquor white vinegar mixed liquor.
5. preparation method for the treatment of diabetes medicament is characterized in that being made up of following steps:
(1) take by weighing by mass percentage: Radix hemerocalis plicatae 60%-80%, Semen Juglandis do branch 20%-40%;
(2) in described Radix hemerocalis plicatae, add 1-5 quality water doubly, very hot oven boiled 5-10 minute, soaked 6-10 hour, and solid-liquid separation will be boiled the Radix hemerocalis plicatae of steeping with after watt baking burnt shape, and it is standby to pulverize powdered, and the liquid after the separation is standby;
(3) described Semen Juglandis is done branch and added 1-5 quality Chinese liquor white vinegar mixed liquid dipping doubly 1-3 hour, solid-liquid separation, the Ramulus Juglandis that soaked is dried in the shade, after adding the Ramulus Juglandis 1-5 quality water boil doubly after described the drying in the shade, change warm fire and boiled 20-30 minute, soaked solid-liquid separation 10-12 hour, liquid after the separation is standby, and the percent by volume of Chinese liquor is 40%-60% in the described Chinese liquor white vinegar mixed liquor;
(4) powder mixes of the liquid of the liquid that described step (2) is prepared, described step (3) preparation and described step (2) preparation is even, promptly makes a kind of medicine for the treatment of diabetes.
6. a kind of preparation method for the treatment of diabetes medicament according to claim 5 is characterized in that described Radix hemerocalis plicatae is 70%, and it is 30% that Semen Juglandis is done branch.
7. a kind of preparation method for the treatment of diabetes medicament according to claim 5, it is characterized in that described step (2) is: in described Radix hemerocalis plicatae, add 3 quality water doubly, very hot oven boiled 8 minutes, soaked 8 hours, solid-liquid separation will be boiled the Radix hemerocalis plicatae of steeping with after watt baking burnt shape, it is standby to pulverize powdered, and the liquid after the separation is standby.
8. a kind of preparation method for the treatment of diabetes medicament according to claim 5, it is characterized in that described step (3) is: described Semen Juglandis is done branch add 3 quality Chinese liquor white vinegar mixed liquid dipping doubly 2 hours, solid-liquid separation, the Ramulus Juglandis that soaked is dried in the shade, add the Ramulus Juglandis 3 quality water boil doubly after described the drying in the shade after, change warm fire and boiled 25 minutes, soaked 11 hours, solid-liquid separation, the liquid after the separation is standby, and the percent by volume of Chinese liquor is 50% in the described Chinese liquor white vinegar mixed liquor.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2008101512196A CN101347572B (en) | 2008-09-02 | 2008-09-02 | Medicament for treating diabetes and preparation method |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2008101512196A CN101347572B (en) | 2008-09-02 | 2008-09-02 | Medicament for treating diabetes and preparation method |
Publications (2)
| Publication Number | Publication Date |
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| CN101347572A true CN101347572A (en) | 2009-01-21 |
| CN101347572B CN101347572B (en) | 2010-10-27 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN2008101512196A Expired - Fee Related CN101347572B (en) | 2008-09-02 | 2008-09-02 | Medicament for treating diabetes and preparation method |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2015129895A1 (en) * | 2014-02-27 | 2015-09-03 | 中島 利博 | Antiobesity agent containing walnut extract |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101073596B (en) * | 2006-05-15 | 2011-02-09 | 中国科学院成都生物研究所 | Alpha-glycosidase inhibitor, its extraction and use |
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2008
- 2008-09-02 CN CN2008101512196A patent/CN101347572B/en not_active Expired - Fee Related
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2015129895A1 (en) * | 2014-02-27 | 2015-09-03 | 中島 利博 | Antiobesity agent containing walnut extract |
| JPWO2015129895A1 (en) * | 2014-02-27 | 2017-03-30 | 中島 利博 | Anti-obesity agent containing walnut extract |
| US10034909B2 (en) | 2014-02-27 | 2018-07-31 | Toshihiro Nakajima | Antiobesity agent containing walnut extract |
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| CN101347572B (en) | 2010-10-27 |
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