CN108992622A - A kind of children's disperse accumulation note plaster - Google Patents

A kind of children's disperse accumulation note plaster Download PDF

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Publication number
CN108992622A
CN108992622A CN201811181441.0A CN201811181441A CN108992622A CN 108992622 A CN108992622 A CN 108992622A CN 201811181441 A CN201811181441 A CN 201811181441A CN 108992622 A CN108992622 A CN 108992622A
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plaster
added
chinese medical
medical extract
children
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张奎昌
张钰
张路
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Pizhou Gas Star Pharmaceutical Technology Service Co Ltd
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Pizhou Gas Star Pharmaceutical Technology Service Co Ltd
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • A61K36/718—Coptis (goldthread)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06—Fungi, e.g. yeasts
    • A61K36/07—Basidiomycota, e.g. Cryptococcus
    • A61K36/076—Poria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/284—Atractylodes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/285—Aucklandia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/484—Glycyrrhiza (licorice)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/58—Meliaceae (Chinaberry or Mahogany family), e.g. Azadirachta (neem)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A61K36/734—Crataegus (hawthorn)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/75—Rutaceae (Rue family)
    • A61K36/752—Citrus, e.g. lime, orange or lemon
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    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/80—Scrophulariaceae (Figwort family)
    • A—HUMAN NECESSITIES
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    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/894—Dioscoreaceae (Yam family)
    • A61K36/8945—Dioscorea, e.g. yam, Chinese yam or water yam
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    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/899—Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
    • A61K36/8998—Hordeum (barley)
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    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/906—Zingiberaceae (Ginger family)
    • A61K36/9062—Alpinia, e.g. red ginger or galangal
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    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/906—Zingiberaceae (Ginger family)
    • A61K36/9064—Amomum, e.g. round cardamom
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    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/906—Zingiberaceae (Ginger family)
    • A61K36/9066—Curcuma, e.g. common turmeric, East Indian arrowroot or mango ginger
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/46—Ingredients of undetermined constitution or reaction products thereof, e.g. skin, bone, milk, cotton fibre, eggshell, oxgall or plant extracts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
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    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30—Extraction of the material
    • A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
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Abstract

The present invention provides a kind of children's disperse accumulation note plaster, which is to make made of matrix without grease and lead oxide.It is characterized in that being made of the raw material of following weight: polyvinyl chloride 55g, dibatyl phithalate 220g, colophony powder 225g, zinc oxide 225g, Chinese medical extract 50g.The method of the present invention is simple and convenient to operate, it is easy to grasp, plaster dosage of the present invention is small, compared with traditional black plaster, with not needing softening before patch, do not slide after pollution clothes, patch, reusable good result, and product is more stable, non-aging to become fragile, and patient generally gladly receives, having shown has preferable advantage and better application prospect compared to black plaster.

Description

A kind of children's disperse accumulation note plaster
Technical field
The invention belongs to external drug preparation technical fields, are related to a kind of plaster, and in particular to a kind of children's disperse accumulation note cream Medicine.
Background technique
Traditional Chinese medicine and pharmacy is the traditional medicine in China, and interior disease external therapy is one of main rule of Chinese medicine.External treatment with Chinese medicine (" warp Skin administration ") method is of long standing and well established, and it is just on the books in B.C. twoth century, China's medicine ancient books and records " interior through Plain Questions ".Motherland's medicine is certainly The application of inner disease outer treat is just taken much count of since Gu, and is constantly able to summarize and improve, in-depth, development, leap.Over the years, interior disease is outer Control the normality rule for having become clinical treatment.
Plaster is one of the Typical Representative of one of China's traditional Chinese medicine preparation conventional dosage forms and inner disease outer treat, early in Has the record of " cream " made of oily, pellet is tempered in the written handbook of Prescription for Emergency of Jin Daige flood.Liu Song's " Liu Juanzi Guiyi Fang, Liu Juanzi " In also there are many " plaster " record." thin " refers to ointment, and " note " refers to plaster.Plaster is more widely applied since Tang, Song, clearly " Li Yue Pianwen, Rhymed Discourse for Topical Remedies " written by Dai Haoshi machine is plaster in the monograph of application aspect, tcm clinical practice and civil cream is still widely used at present Medicine.
Plaster is commonly applied to control aspect outside detumescence, detoxification, myogenic etc., but it passes through outer patch, moreover it is possible to control in playing the role of, such as Wind dispelling is cold and qi and blood, dissolving phlegm ruffian, clearing and activating the channels and collaterals, wind-damp dispelling, controls traumatic injury etc..The effect of plaster is referred on " Li Yue Pianwen, Rhymed Discourse for Topical Remedies " When, there is saying for " cutting " " pulling out ", " all diseases gather place to meaning, and the then disease pulled out goes out certainly, the trouble without deep invagination；Sick institute except, The then heresy cut is autotomyed, the anxiety without the absurd row progress of disease ".
With the improvement of people ' s living standards with the change of way of dining, it is affected to Pediatric diet habit, because of breast milk Insufficient or chronic dietary is uncomfortable, and the object of eating cold and uncooked food excessively causes infantile malnutrition disease to increase, and feared infantile malnutrition due to digestive disturbances or intestinalparasites Central Plains claims five product diseases, i.e., Dyspepsia, gas product, cold product, malnutrition due to parasitic infestation, phlegm product, modern medicine are known as lymphonodi coeliaci inflammation, and clinical manifestation is lean and haggard, food Be intended to not good enough, hair sparse, jaundice easily fall, feverish palms, hobby of eating unusual thing, partial eclipse, stool raw meat glue, abdominal retraction such as boat or abdomen is swollen Swollen, growth and development is slow, is often accompanied by irregular abdominal pain, diarrhea, and duration fever, night is more apparent, malnutrition due to parasitic infestation because overfeeding delicious food it Object is mainly shown as that abdomen is hard greatly, halitosis, and lingual surface is white excessive or has red dot.Its five products disease is more common in children, 1-5 years old especially common Children.To be reduced or avoided to children because painful caused by taking medicine or having an injection, reach therapeutic purposes using plaster outer plaster, it is undoubtedly right The no pain treatment of children has Practical significance.
The most commonly used is black plasters for existing market or medical institutions.Black plaster matrix is really existed by grease type and lead oxide etc. A kind of diachylon being combined under certain condition, though having certain elasticity and viscosity after softening, elasticity is insufficient, sticky mistake It is high.Therefore increase elasticity, it is appropriate to reduce viscosity, it is the direction that should seek in plaster production.
Summary of the invention
The purpose of the present invention is to provide a kind of children's disperse accumulation note plaster.
Plaster of the invention is to make plaster made of matrix without grease and lead oxide.
The purpose of the present invention is what is be achieved by the following scheme:
A kind of children's disperse accumulation note plaster, it is characterized in that the plaster is made of the raw material of following weight:
Polyvinyl chloride 55g, dibatyl phithalate 220g, colophony powder 225g, zinc oxide 225g, Chinese medical extract 50g；
The plaster the preparation method comprises the following steps: weigh the polyvinyl chloride powder of formula ratio, be placed in copper pot, the benzene two of formula ratio be added Formic acid dibutyl ester, stirs evenly, and heats on straight fire, and be stirred continuously, to be heated to 102-105 DEG C, white paste, Being further continued for heating makes temperature rise to 138-142 DEG C, and is stirred continuously turning over materials, until gradually transparent viscous body when, by several times plus Enter rosin fine powder (45 mesh), it is stirring while adding, it is appropriate to cool down after making yellow transparent and homogeneous viscous body, it maintains the temperature at 115-118 DEG C, oxide powder and zinc is added by several times, is sufficiently stirred, then adds Chinese medical extract fine powder (100 mesh), sufficiently stir evenly, Quantitatively spread onto while hot on material of mounting to get；The Chinese medical extract is made by following methods: by coptis 100g, Poria cocos 100g, Rhizoma Atractylodis Macrocephalae 100g, Massa Medicata Fermentata preparata 100g, stir-baked FRUCTUS CRATAEGI 100g, coloured malt 100g, dried orange peel 100g, fructus alpiniae oxyphyllae 100g, costus root 100g, Chinese yam 100g, fructus amomi 100g, fruit of Rangoon creeper 100g, Radix picrorrhizae 100g, Fructus meliae toosendan 100g, curcuma zedoary 100g, Radix Glycyrrhizae 100g are mixed It closes, the ethyl alcohol 8kg that concentration is 62%v/v is added, closed at normal temperature to impregnate 1 week, leaching soak, recycling ethyl alcohol must be concentrated Liquid, it is spare, then add pure water 8kg to decoct 3 hours the dregs of a decoction after immersion, the dregs of a decoction are separately added pure water again by leaching decoction liquor 5kg is decocted 2 hours, and leaching decoction liquor merges secondary decoction liquor, then merges with above-mentioned concentrate, is filtered, and is concentrated, dry It is 6% to water content, is crushed, sieved with 100 mesh sieve, Chinese medical extract is made.
In Chinese medical extract of the present invention:
The coptis: it is bitter, it trembles with fear.Return heart, spleen, stomach, liver, gallbladder, large intestine channel.Heat-clearing and damp-drying drug, purging fire for removing toxin are used for damp and hot feeling of fullness, and vomiting gulps down Acid, dysentery jaundice, unconsciousness due to high fever, heart-fire hyperactivity, dysphoria and insomnia, palpitation and uneasiness, blood-head tells nosebleed, hot eyes, toothache are quenched one's thirst, carbuncle swells Treat sore.
Poria cocos: sweet, light, flat.Return heart, lung, spleen, kidney channel.Clearing damp and promoting diuresis, invigorating the spleen, calming heart.For edema and little urine, phlegm retention is dizzy Throb with fear, spleen eating less, loose stool diarrhea is had no peace of mind, insomnia of palpitating with fear.
Rhizoma Atractylodis Macrocephalae: bitter, sweet, warm.Returns spleen, stomach meridian.Strengthening the spleen and replenishing qi, eliminate dampness and have diuretic effect, hidroschesis, miscarriage prevention.For spleen eating less, abdominal distension Diarrhea.Phlegm retention anti-dazzle nervous, oedema, spontaneous perspiration, threatened abortion.
Divine Comedy: sweet, pungent, warm.Returns spleen, stomach meridian.Promoting digestion and removing indigestion, strengthening the spleen and stomach.For accumulation of food in the stomach and intes tine due to indigestion, abdominal fullness and distention.Deficiency of food Diarrhea.Massa Medicata Fermentata preparata is to take Divine Comedy block, is fried with wheat bran to buff, the sweet perfume (or spice) of Massa Medicata Fermentata preparata smell is chiefly used in eating based on stomach function regulating of being amusing Do not feel like eating, the chamber distention and fullness in the abdomen, increased borborygmus and diarrhea that product is not changed.
Hawthorn: sour, sweet, tepor.Returns spleen, stomach, Liver Channel.Food digesting stomach fortifying, scattered stasis change turbid lipid-loweringing.For meat stagnation, Gastral cavilty turgor, diarrhea dysentery abdominal pain, extravasated blood menostasis, postpartum stasis, confidant sting, chest impediment and cardialgia, hernia pain, hyperlipemia.Fry mountain Short, bristly hair or beard is to take net haw flakes, is fried muddy to discoloration.Stir-baked FRUCTUS CRATAEGI tart flavour weakens, and can mitigate the irritation to stomach, be good at promoting digestion and removing indigestion, more For eating accumulation.
Malt: sweet, flat.Returns spleen, stomach meridian.Promoting the circulation of qi helps digestion, spleen benefiting and stimulating the appetite, delaactation dissipate-swelling.Do not disappear for having indigestion, the stomach duct and abdomen side of body Bitterly, spleen eating less, milk smoulders, distending pain of the breast, weaning women, liver-depressed hypochondrium pain, stomachache due to emotional depression and the hyperactive liver-qi attacking the stomach.Coloured malt is to take net malt, is fried To brown color.Coloured malt partial temperature and gas is fragrant, be longer than promoting the circulation of qi helps digestion, delaactation dissipate-swelling is chiefly used in dyspepsia, weaning women.
Dried orange peel: bitter, acrid in flavour and warm in nature.Return lung, the spleen channel.Regulating qi-flowing for strengthening spleen is eliminating dampness and eliminating phlegm.For abdominal fullness and distention, deficiency of food is vomited and diarrhoea, cough Abundant expectoration.
Fructus alpiniae oxyphyllae: impurity is removed for intelligence development ripening fruits and shell obtains.Acrid flavour, temperature.Returns spleen, kidney channel.Warm kidney controlling nocturnal emission with astringent drugs place Urine, it is warming spleen and stopping diarrha to take the photograph saliva.For enuresis with renal asthenia, frequent urination, gonorrhoea of passing out semen, malaria diarrhea, crymodynia in abdomen, the more salivas of mouth.
Costus root: bitter, pungent, warm.Returns spleen, stomach, large intestine, tri-jiao channel.Promoting qi circulation and relieving pain, reinforcing spleen to promote digestion.It is swollen for chest side of body, stomach duct and abdomen Bitterly, weight after rush down dysentery, dyspepsia, do not feel like eating.
Chinese yam: sweet, flat.Returns spleen, lung, kidney channel.Tonifying spleen nourishing the stomach, engender liquid and benefic lung, kidney tonifying arresting seminal emission.For spleen eating less, chronic diarrhea Incessantly, the deficiency syndrome of the lung is breathed with cough, emission due to the kidney deficiency, leukorrhagia, frequent micturition, and abnormal heat is quenched one's thirst.
Fructus amomi: acrid in flavour and warm in nature.Returns spleen, stomach, kidney channel.Dampness elimination appetizing, warming spleen and stopping diarrha, regulating the flow of vital energy and preventing miscarriage.For turbi damp obstructing in middle-JIAO, gastral cavity ruffian It is not hungry, deficiency-cold in spleen and stomach, vomiting and diarrhea, hyperemesis gravidarum, threatened abortion.
The fruit of Rangoon creeper: sweet, warm.Returns spleen, stomach meridian.Killing insect and eliminating accumulation.For roundworm disease, enterobiasis, abdominal pain due to enterositosis, infantile malnutrition.
Radix picrorrhizae: it is bitter, it trembles with fear.Return liver, stomach, large intestine channel.Reducing the asthenic fever, treating infantile malnutrition wide fever, clearing away damp-heat.For osteopyrexia and fever, children's infantile malnutrition due to digestive disturbances or intestinalparasites Heat, damp-heat dysentery, jaundice urinate red, hemorrhoid gall.
Fructus meliae toosendan: it is bitter, it trembles with fear；It is slightly poisonous.Return liver, small intestine, bladder meridian.It is soothing the liver to expel the heat-evil, promoting qi circulation and relieving pain, desinsection.For liver depression Change fire, chest side of body, abdominal distention, hernia pain, abdominal pain due to enterositosis.
Curcuma zedoary: pungent, bitter, temperature.Return liver, the spleen channel.Promoting the circulation of qi blood-breaking, clearing stagnation and killing pain.Yong Yu abdominal mass and lump, blood stasis closed, thoracic obstruction It is pained, dyspepsia distending pain.
Radix Glycyrrhizae: sweet and neutral, return heart, lung, stomach meridian.It invigorates the spleen and benefits qi, clearing heat and detoxicating, expelling phlegm and arresting coughing, relieving spasm to stop pain, reconciliation drug storage. For weakness of the spleen and the stomach, fatigue and weakness, shortness of breath and palpitation, coughing with a lot of sputum, stomach duct and abdomen, four limbs contraction, carbuncle sore tumefacting virus, alleviation drug poison It is property, strong.
All Chinese medicine materials used in the present invention are commercially available standard compliant commodity, and required parched medicinal material presses Chinese medicine The related stringent big gun moxibustion processing program frying of big gun moxibustion specification.
In conclusion by adopting the above-described technical solution, the beneficial effects of the present invention are:
The present invention be it is a kind of do not use grease and lead oxide as the plaster of matrix, saved edible oil, the method for the present invention simply, It is easy to operate, it is easy to grasp, the cumbersome works such as " wasting lamp oil by not sleeping at night " when preparing traditional black plaster matrix, " descending pellet ", " releasing fire-toxin " can be omitted Skill also avoids the danger for easily causing burning and lead poisoning etc..Plaster dosage of the invention is small, it is easy to faint by sticking mind Cave (navel) reaches absorption and plays therapeutic efficiency, be allowed to show help digestion, disperse accumulation, the ruffian that disappears, the stagnant, pain that disappears that disappears, dissipate-swelling, heat-clearing it is comprehensive Close therapeutic effect.
Plaster of the invention has and does not slide after not needing softening, not pollution clothes, patch before pasting compared with traditional black plaster Dynamic, reusable good result, and product is more stable, non-aging to become fragile, the shelf-life is longer.
Plaster dosage prepared by the present invention is small, easy to use, and every note sticks on SHENJUE acupoint (i.e. on navel), dressing 1 in three days Secondary, 5 notes amount to 15 days as one therapeutic course, compare use through tens of infants, and as a result the black plaster with the preparation of Chinese medicine formula does not have Significant difference obtains preferable clinical therapeutic efficacy, and patient generally gladly receives, shown compared to black plaster have compared with Good advantage and better application prospect.
Specific embodiment
Embodiment 1
1, the preparation of Chinese medical extract:
By coptis 100g, Poria cocos 100g, Rhizoma Atractylodis Macrocephalae 100g, Massa Medicata Fermentata preparata 100g, stir-baked FRUCTUS CRATAEGI 100g, coloured malt 100g, dried orange peel 100g, benefit Intelligence benevolence 100g, costus root 100g, Chinese yam 100g, fructus amomi 100g, fruit of Rangoon creeper 100g, Radix picrorrhizae 100g, Fructus meliae toosendan 100g, curcuma zedoary The ethyl alcohol 8kg that weight concentration is 62%v/v is added in 100g, Radix Glycyrrhizae 100g mixing, and closed at normal temperature to impregnate 1 week, leaching is impregnated Liquid recycles ethyl alcohol, obtains concentrate, spare, then adds pure water 8kg to decoct 3 hours the dregs of a decoction after immersion, leaching decoction liquor, separately The dregs of a decoction are added into pure water 5kg again, are decocted 2 hours, leaching decoction liquor merges secondary decoction liquor, then merges with above-mentioned concentrate, It is filtered, is concentrated, drying to water content is 6%, is crushed, sieves with 100 mesh sieve obtained Chinese medical extract.
2, the preparation of plaster:
Polyvinyl chloride powder 55g is weighed, is placed in copper pot, dibatyl phithalate 220g is added, stirs evenly, is added on straight fire Heat, and being stirred continuously, to be heated to 105 DEG C, white paste, being further continued for heating makes temperature rise to 142 DEG C, and constantly stirs Mix turning over materials, until gradually transparent viscous body when, 45 mesh rosin fine powder 225g are added by several times, it is stirring while adding, make It is appropriate to cool down after yellow transparent and homogeneous viscous body, 115 DEG C are maintained the temperature at, oxide powder and zinc 225g is added by several times, is sufficiently stirred, Then above-mentioned 100 mesh fine powder 50g of gained Chinese medical extract is added, sufficiently stirs evenly, spreads on nonwoven cloth material while hot, i.e., ?；5 grams of the medicine (weight) amount of every note plaster.
Application effect:
The present invention prepares gained plaster application method: it is only limitted to external application, is directly pasted on SHENJUE acupoint (on navel), is pasted within 3 days 1,5 patches (15 days) as a treatment course.
It is clinically used for infantile malnutrition disease, case 62, be 1-5 years old children, wherein male 40, female 22, through one A course of therapy, wherein 58 healings, 4 improvements, effective percentage are 100%, cure rate 93.55%.Case is cured without an example Rebound phenomenon, and have no any bad reflection.

Claims (1)

1. a kind of treat children's disperse accumulation note plaster, it is characterized in that the plaster is made of the raw material of following weight:
Polyvinyl chloride 55g, dibatyl phithalate 220g, colophony powder 225g, zinc oxide 225g, Chinese medical extract 50g；
Preparation method are as follows: the polyvinyl chloride powder for weighing formula ratio is placed in copper pot, and two fourth of phthalic acid of formula ratio is added Ester stirs evenly, and heats on straight fire, and be stirred continuously, to be heated to 102-105 DEG C, white paste, be further continued for plus Heat makes temperature rise to 138-142 DEG C, and is stirred continuously turning over materials, until gradually transparent viscous body when, by several times be added rosin 45 Mesh fine powder, it is stirring while adding, it is appropriate to cool down after making yellow transparent and homogeneous viscous body, 115-118 DEG C is maintained the temperature at, Oxide powder and zinc is added by several times, is sufficiently stirred, then adds 100 mesh fine powder of Chinese medical extract, sufficiently stir evenly, quantitative booth applies while hot In on material of mounting to get；Wherein the Chinese medical extract is made by following methods: by coptis 100g, Poria cocos 100g, Rhizoma Atractylodis Macrocephalae 100g, Massa Medicata Fermentata preparata 100g, stir-baked FRUCTUS CRATAEGI 100g, coloured malt 100g, dried orange peel 100g, fructus alpiniae oxyphyllae 100g, costus root 100g, Chinese yam Concentration is added in 100g, fructus amomi 100g, fruit of Rangoon creeper 100g, Radix picrorrhizae 100g, Fructus meliae toosendan 100g, curcuma zedoary 100g, Radix Glycyrrhizae 100g mixing Closed at normal temperature to impregnate 1 week for the ethyl alcohol 8kg of 62%v/v, leaching soak, recycling ethyl alcohol obtains concentrate, spare, then will The dregs of a decoction after immersion add pure water 8kg to decoct 3 hours, leaching decoction liquor, and the dregs of a decoction are separately added pure water 5kg again, decoct 2 hours, Leaching decoction liquor merges secondary decoction liquor, then merges with above-mentioned concentrate, is filtered, concentration, and drying to water content is 6%, It is crushed, is sieved with 100 mesh sieve, Chinese medical extract is made.
CN201811181441.0A 2018-10-11 2018-10-11 A kind of children's disperse accumulation note plaster Withdrawn CN108992622A (en)

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Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1640483A (en) * 2004-05-17 2005-07-20 潘金来 Musk radix thunbergiae grandiflorae ointment

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1640483A (en) * 2004-05-17 2005-07-20 潘金来 Musk radix thunbergiae grandiflorae ointment

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
王运利: "《现代中医收藏方典》", 30 November 2011, 陕西科学技术出版社 *

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