CN108939017A - A kind of preparation method of children's disperse accumulation note black plaster - Google Patents

A kind of preparation method of children's disperse accumulation note black plaster Download PDF

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Publication number
CN108939017A
CN108939017A CN201811181296.6A CN201811181296A CN108939017A CN 108939017 A CN108939017 A CN 108939017A CN 201811181296 A CN201811181296 A CN 201811181296A CN 108939017 A CN108939017 A CN 108939017A
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black plaster
oil
preparation
plaster
fructus
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张奎昌
张钰
张路
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Pizhou Gas Star Pharmaceutical Technology Service Co Ltd
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Pizhou Gas Star Pharmaceutical Technology Service Co Ltd
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • A61K36/718—Coptis (goldthread)
    • A—HUMAN NECESSITIES
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06—Fungi, e.g. yeasts
    • A61K36/07—Basidiomycota, e.g. Cryptococcus
    • A61K36/076—Poria
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    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A—HUMAN NECESSITIES
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    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/284—Atractylodes
    • A—HUMAN NECESSITIES
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    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/285—Aucklandia
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/484—Glycyrrhiza (licorice)
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    • A61K36/185—Magnoliopsida (dicotyledons)
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    • A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
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    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
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Abstract

The present invention provides a kind of preparation method of children's disperse accumulation note black plaster, which is made of the raw material of following weight: coptis 100g, Poria cocos 100g, Rhizoma Atractylodis Macrocephalae 100g, Massa Medicata Fermentata preparata 100g, stir-baked FRUCTUS CRATAEGI 100g, coloured malt 100g, dried orange peel 100g, fructus alpiniae oxyphyllae 100g, costus root 100g, Chinese yam 100g, fructus amomi 100g, fruit of Rangoon creeper 100g, Radix picrorrhizae 100g, Fructus meliae toosendan 100g, curcuma zedoary 100g, Radix Glycyrrhizae 100g, vegetable oil 3500g, yellow lead 1500g.The method of the present invention is to be blended into Chinese medical extract using alseodaphne hainanensis as matrix, and a kind of novel improved type black plaster is made, and preparation process is that medicinal material is smashed to carry out seepage pressure effects, it is concentrated that thick paste is made, then through refining oil, lower pellet, releasing fire-toxin changes cream and converts medicine, booth apply and etc. black plaster is made.For the method for black plaster of the present invention compared with the black plaster of normal conventional preparation method, dosage is small, and good effect, receives extraordinary application effect.

Description

A kind of preparation method of children's disperse accumulation note black plaster
Technical field
The invention belongs to external drug preparation technical fields, are related to a kind of black plaster, and in particular to a kind of children's disperse accumulation note The preparation method of modified black plaster.
Background technique
Traditional Chinese medicine and pharmacy is the traditional medicine in China, and interior disease external therapy is one of main rule of Chinese medicine.External treatment with Chinese medicine (" warp Skin administration ") method is of long standing and well established, and it is just on the books in B.C. twoth century, China's medicine ancient books and records " interior through Plain Questions ".Motherland's medicine is certainly The application of inner disease outer treat is just taken much count of since Gu, and is constantly able to summarize and improve, in-depth, development, leap.Over the years, interior disease is outer Control the normality rule for having become clinical treatment.
Plaster is one of the Typical Representative of one of China's traditional Chinese medicine preparation conventional dosage forms and inner disease outer treat, early in Has the record of " cream " made of oily, pellet is tempered in the written handbook of Prescription for Emergency of Jin Daige flood.Liu Song's " Liu Juanzi Guiyi Fang, Liu Juanzi " In also there are many " plaster " record." thin " refers to ointment, and " note " refers to plaster.Plaster is more widely applied since Tang, Song, clearly " Li Yue Pianwen, Rhymed Discourse for Topical Remedies " written by Dai Haoshi machine is plaster in the monograph of application aspect, tcm clinical practice and civil cream is still widely used at present Medicine.
Plaster is commonly applied to control aspect outside detumescence, detoxification, myogenic etc., but it passes through outer patch, moreover it is possible to control in playing the role of, such as Wind dispelling is cold and qi and blood, dissolving phlegm ruffian, clearing and activating the channels and collaterals, wind-damp dispelling, controls traumatic injury etc..The effect of plaster is referred on " Li Yue Pianwen, Rhymed Discourse for Topical Remedies " When, there is saying for " cutting " " pulling out ", " all diseases gather place to meaning, and the then disease pulled out goes out certainly, the trouble without deep invagination；Sick institute except, The then heresy cut is autotomyed, the anxiety without the absurd row progress of disease ".
With the improvement of people ' s living standards with the change of way of dining, it is affected to Pediatric diet habit, because of breast milk Insufficient or chronic dietary is uncomfortable, and the object of eating cold and uncooked food excessively causes infantile malnutrition disease to increase, and feared infantile malnutrition due to digestive disturbances or intestinalparasites Central Plains claims five product diseases, i.e., Dyspepsia, gas product, cold product, malnutrition due to parasitic infestation, phlegm product, modern medicine are known as lymphonodi coeliaci inflammation, and clinical manifestation is lean and haggard, food Be intended to not good enough, hair sparse, jaundice easily fall, feverish palms, hobby of eating unusual thing, partial eclipse, stool raw meat glue, abdominal retraction such as boat or abdomen is swollen Swollen, growth and development is slow, is often accompanied by irregular abdominal pain, diarrhea, and duration fever, night is more apparent, malnutrition due to parasitic infestation because overfeeding delicious food it Object is mainly shown as that abdomen is hard greatly, halitosis, and lingual surface is white excessive or has red dot.Its five products disease is more common in children, 1-5 years old especially common Children.To be reduced or avoided to children because painful caused by taking medicine or having an injection, reach therapeutic purposes using plaster outer plaster, it is undoubtedly right The no pain treatment of children has Practical significance.
Summary of the invention
The purpose of the present invention is to provide a kind of children's disperse accumulation note black plasters.
The purpose of the present invention is what is be achieved by the following scheme:
A kind of preparation method of children's disperse accumulation note black plaster, it is characterized in that the black plaster is made of the raw material of following weight:
Coptis 100g, Poria cocos 100g, Rhizoma Atractylodis Macrocephalae 100g, Massa Medicata Fermentata preparata 100g, stir-baked FRUCTUS CRATAEGI 100g, coloured malt 100g, dried orange peel 100g, intelligence development Benevolence 100g, costus root 100g, Chinese yam 100g, fructus amomi 100g, fruit of Rangoon creeper 100g, Radix picrorrhizae 100g, Fructus meliae toosendan 100g, curcuma zedoary 100g, Radix Glycyrrhizae 100g, vegetable oil 3500g, yellow lead 1500g.
The preparation method of the black plaster:
(1) medicinal material extract: taking 16 kinds of recipe quantity Chinese medicine, counts 1600g, is broken into 24 mesh coarse powder, mixes, and adjusts to dilute sulfuric acid The concentration that pH value is 4.5 is 72%(v/v) ethyl alcohol be solvent, moisten medicinal material 8h, be then charged into percolator, spread compression, medicine Face covers one layer of gauze, and being added and adjusting the concentration that pH value is 4.5 with dilute sulfuric acid in right amount is 72%(v/v) ethyl alcohol is to high drug charge level 12cm places 55h, starts diacolation, coutroi velocity is in 0.8ml/min-1, it adds solvent at any time above, percolate is collected below, until Until percolate is substantially colorless, percolate is evaporated under reduced pressure recycling ethyl alcohol with cucurbit and obtains concentrate, then concentrate is inclined into steaming Continue water-bath in hair container and is concentrated by evaporation the thick paste to moisture content less than 12%, it is spare；
(2) it refines oil: taking the vegetable oil 3500g of recipe quantity, be placed in copper pot, straight fire heating is tempered, under constant stirring until oil temperature Green cigarette is transmitted from white cigarette up to 290 DEG C, stops heating, wait be naturally cooling to 95 DEG C；
(3) red under: it takes yellow lead to set and heats fried dry in pot, after cold, cross 90 meshes, weigh 1500g, be slowly added in the oil refined, It is heated to foam appearance under constant stirring, at once from fire (therefore alseodaphne hainanensis effect is exothermic reaction, easily excessive), to oily and red Effect completely, i.e., fades to dark brown by vermilion, and not exclusively can suitably heat if any reaction makes its effect completely, sufficiently stirs It is even；
(4) releasing fire-toxin: the hot cream that will have been endured is poured into cold water slowly, and cream is sticked together after cold and torn up, soaked in flowing cool water by stirring Bubble 12 days；
(5) change cream and convert medicine: taking out cream block from water, set in copper pot after heating and melting, place to temperature to 95 DEG C, be blended into (1) system The medicinal material thick paste obtained, stirs, and then places cooling and keeps plaster in 62-65 DEG C of temperature；
(6) booth applies: by lotion, 8 grams of taken amount, booth are stored in packaging in the circle in kraft back, painting diameter 6cm, folding while hot In box, store in a cool and dry place to obtain the final product.
Wherein vegetable oil can be used cotton seed oil, rape seed oil, peanut oil, maize germ oil, soybean oil, sesame oil and (be commonly called as perfume (or spice) Oil), but in practical applications still with sesame oil be it is best, its advantage is that foam is few when tempering, be conducive to operate, and manufactured plaster Bright in color, property is viscous, high-quality, and currently preferred is sesame oil (sesame oil).
Yellow lead, also known as minium, red lead, red lead, Dong Dan, Tao Dan are crocus, matter weight, powdered, main component four Aoxidize three lead (Pb3O4), purity requirement is 95% or more.When in use as being polymerized to particle containing moisture, lower Dan Shiyi is sunken to yellow lead The bottom of a pan is not easy sufficiently to react with oil, thus before use should in iron pan fried dry, and sieving to obtain fine powder adds in oil.
The present invention is to be blended into the medicinal extract that each medicine composition extracts using alseodaphne hainanensis as matrix, a kind of novel improved black plaster is made, Preparation process is that medicinal material is smashed to carry out seepage pressure effects, concentrated that medicinal extract is made, then is refined oil, lower pellet, " fire toxin ", change cream is gone to convert Medicine, booth apply and etc. black plaster is made.
In the present composition:
The coptis: it is bitter, it trembles with fear.Return heart, spleen, stomach, liver, gallbladder, large intestine channel.Heat-clearing and damp-drying drug, purging fire for removing toxin are used for damp and hot feeling of fullness, and vomiting gulps down Acid, dysentery jaundice, unconsciousness due to high fever, heart-fire hyperactivity, dysphoria and insomnia, palpitation and uneasiness, blood-head tells nosebleed, hot eyes, toothache are quenched one's thirst, carbuncle swells Treat sore.
Poria cocos: sweet, light, flat.Return heart, lung, spleen, kidney channel.Clearing damp and promoting diuresis, invigorating the spleen, calming heart.For edema and little urine, phlegm retention is dizzy Throb with fear, spleen eating less, loose stool diarrhea is had no peace of mind, insomnia of palpitating with fear.
Rhizoma Atractylodis Macrocephalae: bitter, sweet, warm.Returns spleen, stomach meridian.Strengthening the spleen and replenishing qi, eliminate dampness and have diuretic effect, hidroschesis, miscarriage prevention.For spleen eating less, abdominal distension Diarrhea.Phlegm retention anti-dazzle nervous, oedema, spontaneous perspiration, threatened abortion.
Divine Comedy: sweet, pungent, warm.Returns spleen, stomach meridian.Promoting digestion and removing indigestion, strengthening the spleen and stomach.For accumulation of food in the stomach and intes tine due to indigestion, abdominal fullness and distention.Deficiency of food Diarrhea.Massa Medicata Fermentata preparata is to take Divine Comedy block, is fried with wheat bran to buff, the sweet perfume (or spice) of Massa Medicata Fermentata preparata smell is chiefly used in eating based on stomach function regulating of being amusing Do not feel like eating, the chamber distention and fullness in the abdomen, increased borborygmus and diarrhea that product is not changed.
Hawthorn: sour, sweet, tepor.Returns spleen, stomach, Liver Channel.Food digesting stomach fortifying, scattered stasis change turbid lipid-loweringing.For meat stagnation, Gastral cavilty turgor, diarrhea dysentery abdominal pain, extravasated blood menostasis, postpartum stasis, confidant sting, chest impediment and cardialgia, hernia pain, hyperlipemia.Fry mountain Short, bristly hair or beard is to take net haw flakes, is fried muddy to discoloration.Stir-baked FRUCTUS CRATAEGI tart flavour weakens, and can mitigate the irritation to stomach, be good at promoting digestion and removing indigestion, more For eating accumulation.
Malt: sweet, flat.Returns spleen, stomach meridian.Promoting the circulation of qi helps digestion, spleen benefiting and stimulating the appetite, delaactation dissipate-swelling.Do not disappear for having indigestion, the stomach duct and abdomen side of body Bitterly, spleen eating less, milk smoulders, distending pain of the breast, weaning women, liver-depressed hypochondrium pain, stomachache due to emotional depression and the hyperactive liver-qi attacking the stomach.Coloured malt is to take net malt, is fried To brown color.Coloured malt partial temperature and gas is fragrant, be longer than promoting the circulation of qi helps digestion, delaactation dissipate-swelling is chiefly used in dyspepsia, weaning women.
Dried orange peel: bitter, acrid in flavour and warm in nature.Return lung, the spleen channel.Regulating qi-flowing for strengthening spleen is eliminating dampness and eliminating phlegm.For abdominal fullness and distention, deficiency of food is vomited and diarrhoea, cough Abundant expectoration.
Fructus alpiniae oxyphyllae: impurity is removed for intelligence development ripening fruits and shell obtains.Acrid flavour, temperature.Returns spleen, kidney channel.Warm kidney controlling nocturnal emission with astringent drugs place Urine, it is warming spleen and stopping diarrha to take the photograph saliva.For enuresis with renal asthenia, frequent urination, gonorrhoea of passing out semen, malaria diarrhea, crymodynia in abdomen, the more salivas of mouth.
Costus root: bitter, pungent, warm.Returns spleen, stomach, large intestine, tri-jiao channel.Promoting qi circulation and relieving pain, reinforcing spleen to promote digestion.It is swollen for chest side of body, stomach duct and abdomen Bitterly, weight after rush down dysentery, dyspepsia, do not feel like eating.
Chinese yam: sweet, flat.Returns spleen, lung, kidney channel.Tonifying spleen nourishing the stomach, engender liquid and benefic lung, kidney tonifying arresting seminal emission.For spleen eating less, chronic diarrhea Incessantly, the deficiency syndrome of the lung is breathed with cough, emission due to the kidney deficiency, leukorrhagia, frequent micturition, and abnormal heat is quenched one's thirst.
Fructus amomi: acrid in flavour and warm in nature.Returns spleen, stomach, kidney channel.Dampness elimination appetizing, warming spleen and stopping diarrha, regulating the flow of vital energy and preventing miscarriage.For turbi damp obstructing in middle-JIAO, gastral cavity ruffian It is not hungry, deficiency-cold in spleen and stomach, vomiting and diarrhea, hyperemesis gravidarum, threatened abortion.
The fruit of Rangoon creeper: sweet, warm.Returns spleen, stomach meridian.Killing insect and eliminating accumulation.For roundworm disease, enterobiasis, abdominal pain due to enterositosis, infantile malnutrition.
Radix picrorrhizae: it is bitter, it trembles with fear.Return liver, stomach, large intestine channel.Reducing the asthenic fever, treating infantile malnutrition wide fever, clearing away damp-heat.For osteopyrexia and fever, children's infantile malnutrition due to digestive disturbances or intestinalparasites Heat, damp-heat dysentery, jaundice urinate red, hemorrhoid gall.
Fructus meliae toosendan: it is bitter, it trembles with fear；It is slightly poisonous.Return liver, small intestine, bladder meridian.It is soothing the liver to expel the heat-evil, promoting qi circulation and relieving pain, desinsection.For liver depression Change fire, chest side of body, abdominal distention, hernia pain, abdominal pain due to enterositosis.
Curcuma zedoary: pungent, bitter, temperature.Return liver, the spleen channel.Promoting the circulation of qi blood-breaking, clearing stagnation and killing pain.Yong Yu abdominal mass and lump, blood stasis closed, thoracic obstruction It is pained, dyspepsia distending pain.
Radix Glycyrrhizae: sweet and neutral, return heart, lung, stomach meridian.It invigorates the spleen and benefits qi, clearing heat and detoxicating, expelling phlegm and arresting coughing, relieving spasm to stop pain, reconciliation drug storage. For weakness of the spleen and the stomach, fatigue and weakness, shortness of breath and palpitation, coughing with a lot of sputum, stomach duct and abdomen, four limbs contraction, carbuncle sore tumefacting virus, alleviation drug poison It is property, strong.
All Chinese medicine materials used in the present invention are commercially available standard compliant commodity, and required parched medicinal material presses Chinese medicine The related stringent big gun moxibustion processing program frying of big gun moxibustion specification.
In conclusion by adopting the above-described technical solution, the beneficial effects of the present invention are:
Thick paste is made by extracting, being concentrated using pure traditional Chinese medicine raw material in system of the present invention, then converts through oil refining, lower pellet, releasing fire-toxin, change cream Medicine, booth apply step and modified black plaster are made, and the black plaster of preparation has very strong penetration power, it is easy to by the mind sticked Cave of fainting reaches absorption and plays therapeutic efficiency, be allowed to show help digestion, disperse accumulation, the ruffian that disappears, the stagnant, pain that disappears that disappears, dissipate-swelling, heat-clearing, promoting blood circulation Combined therapy effect.
Black plaster prepared by the present invention is easy to use, often applys and is affixed on navel (i.e. SHENJUE acupoint), changes within three days 1 time, 5 notes 15 Days as a treatment course.For black plaster of the invention compared with the black plaster of normal conventional preparation method, dosage is small, and curative effect is preferable, through 362 The use of infant, effective percentage is 100%, and cure rate is 98%.It has no adverse reaction after medication, the application treatment of black plaster is reduced Children's takes medicine or injects bring pain, decreases the side effect therefore generated.It is played for the treatment of infantile malnutrition Good social effect.
The present invention carries out seepage pressure effects to medicinal material using effectively succession prescription, through modern means of science and technology, medicinal extract is made in concentration, Then through oil refining, it is lower it is red, go " fire toxin ", change that cream converts medicine, booth applies and modified black plaster is made, this black plaster is received non- Often good effect is the treatment and rehabilitation of infantile malnutrition, forms better application market, generates preferable medical treatment contribution.
Specific embodiment
Embodiment
1, prescription
Coptis 100g, Poria cocos 100g, Rhizoma Atractylodis Macrocephalae 100g, Massa Medicata Fermentata preparata 100g, stir-baked FRUCTUS CRATAEGI 100g, coloured malt 100g, dried orange peel 100g, intelligence development Benevolence 100g, costus root 100g, Chinese yam 100g, fructus amomi 100g, fruit of Rangoon creeper 100g, Radix picrorrhizae 100g, Fructus meliae toosendan 100g, curcuma zedoary 100g, Radix Glycyrrhizae 100g, sesame oil 3500g, yellow lead 1500g.
2, preparation method
(1) medicinal material extract: taking 16 kinds of recipe quantity Chinese medicine, juice 1600g, is broken into 24 mesh coarse powder, mixes, and adjusts to dilute sulfuric acid The concentration that pH value is 4.5 is 72%(v/v) ethyl alcohol be solvent, moisten medicinal material 8h, be then charged into percolator, spread compression, medicine Face covers one layer of gauze, and being added and adjusting the concentration that pH value is 4.5 with dilute sulfuric acid in right amount is 72%(v/v) ethyl alcohol is to high drug charge level 12cm places 55h, starts diacolation, and coutroi velocity adds solvent in 2ml/min at any time above, percolate is collected below, until seeping Until liquid of filtering is substantially colorless, percolate is evaporated under reduced pressure recycling ethyl alcohol with cucurbit and obtains concentrate, then concentrate is inclined into evaporation Continue water-bath in container to be concentrated by evaporation to moisture content to be the thick paste less than 12%, it is spare；(2) it refines oil: taking the plant of recipe quantity Oily 3500g is placed in copper pot, and straight fire heating is tempered under constant stirring, until oil temperature transmits green cigarette from white cigarette up to 290 DEG C, stopped It only heats, wait be naturally cooling to 95 DEG C；(3) red under: it takes and heats fried dry in yellow lead to pot, after cold, cross 90 meshes, weigh 1500g, Be slowly added in the oil refined, be heated to foam appearance under constant stirring, at once from fire (therefore alseodaphne hainanensis effect be that heat release is anti- It answers, easily excessive), it is acted on completely to oil with red, i.e., dark brown is faded to by vermilion, not exclusively can suitably heat if any reaction makes It is acted on completely, is sufficiently stirred evenly；(4) releasing fire-toxin: the hot cream that will have been endured is poured into cold water slowly, and cream is sticked together after cold and torn by stirring It is broken, it is impregnated 12 days in flowing cool water；(5) change cream and convert medicine: taking out cream block from water, in straight copper pot after heating and melting, place extremely Temperature is blended into medicinal material thick paste made from step (1), stirs to 95 DEG C, then places cooling and keeps plaster in 62-65 DEG C temperature；(6) booth applies: lotion 8 grams of taken amount while hot are spread out in the circle in kraft back, painting diameter 6cm, folding is stored in In packing box, in a cool and dry place to obtain the final product, the dose of every note plaster is no less than 8 grams, it is proposed that 10-12 grams for storage.
The present invention prepares gained black plaster application method: black plaster is only limitted to external application, is affixed on SHENJUE acupoint (tripe after slightly hot Navel), 3 days notes, 5 notes are (15 days) as a treatment course.
Typical case:
Case 1: Yang, male, 10 months, breast milk was insufficient, based on powder of breast-feeding, there is nearly two wheat harvesting periods time, often fever, cough It coughs, night cries and screams, abdominal distention, normal diarrhea, hypoevolutism；Lose money in a business invention black plaster note, changes within 3 days primary, pastes five notes altogether, and 15 It, cures, and without rebound phenomenon, and have no any adverse reaction.
Case 2: Liu, male, 3 years old, parents reaction, the virgin long-term loss of appetite of the disease, appetite was few and partial eclipse, sign show To be lean and haggard, hair sparse, usually often there are low-heat at abdominal distention, abdominal pain, night；Lose money in a business invention black plaster, changes within 3 days Once, it after patch 5 note 15 days, cures, no rebound phenomenon.
Case 3: Liang, male, 5 years old, parent told existing six months loss of appetite in generation, often had abdominal pain, night abdomen is swollen It is swollen, often there is low-heat.Observation face jaundice, it is thin；Lose money in a business the changing for black plaster 3 days 1 time of invention, after 1 course for the treatment of of totally 5 notes (15 days), It cures, and without any adverse reactions.
Case 4: Wu, female, 2 years old, diet significantly reduced more than the moon, apathetic depressed, defecates less and glues, with raw meat Smelly, night egersis is cry and screamed, low-heat and with cough；Lose money in a business the black plaster of invention, changes within 3 days primary, pastes five notes altogether, 15 days, controls More, and without rebound phenomenon.

Claims (2)

1. a kind of preparation method of children's disperse accumulation note black plaster, which is characterized in that it is made of the raw material of following weight: the coptis 100g, Poria cocos 100g, Rhizoma Atractylodis Macrocephalae 100g, Massa Medicata Fermentata preparata 100g, stir-baked FRUCTUS CRATAEGI 100g, coloured malt 100g, dried orange peel 100g, fructus alpiniae oxyphyllae 100g, Costus root 100g, Chinese yam 100g, fructus amomi 100g, fruit of Rangoon creeper 100g, Radix picrorrhizae 100g, Fructus meliae toosendan 100g, curcuma zedoary 100g, Radix Glycyrrhizae 100g, vegetable oil 3500g, yellow lead 1500g；Preparation method is as follows: (1) medicinal material extract: taking 16 kinds of recipe quantity Chinese medicine, meter 1600g is broken into 24 mesh coarse powder, mixes, and adjusting the 72%v/v ethyl alcohol that pH value is 4.5 to dilute sulfuric acid is solvent, moistens medicinal material 8h is then charged into percolator, spreads compression, and powder covers one layer of gauze, and being added and adjusting pH value with dilute sulfuric acid in right amount is 4.5 72%v/v ethyl alcohol places 55h, starts diacolation, coutroi velocity is in 0.8ml/min to high drug charge level 12cm-1, mend at any time above Solubilization matchmaker, is collected below percolate, until percolate is substantially colorless, percolate is evaporated under reduced pressure recycling ethyl alcohol with cucurbit and is obtained Concentrate, then concentrate is inclined into continuation water-bath in container for evaporation and is concentrated by evaporation the thick paste to moisture content less than 12%, it is spare； (2) it refines oil: taking the vegetable oil 3500g of recipe quantity, be placed in copper pot, straight fire heating is tempered, under constant stirring until oil temperature reaches 290 DEG C are transmitted green cigarette from white cigarette, stop heating, wait be naturally cooling to 95 DEG C；(3) red under: it takes yellow lead to set and heats fried dry in pot, After cold, 90 meshes are crossed, 1500g is weighed, is slowly added in the oil refined, be heated to foam appearance under constant stirring, at once It is complete to oil and red effect from fire, i.e., dark brown is faded to by vermilion, not exclusively can suitably heat if any reaction makes its effect Completely, it sufficiently stirs evenly；(4) releasing fire-toxin: the hot cream that will have been endured is poured into cold water slowly, and cream is sticked together after cold and torn up by stirring, Yu Liu It is impregnated 12 days in dynamic cold water；(5) change cream and convert medicine: taking out cream block from water, set in copper pot after heating and melting, placement to temperature to 95 DEG C, it is blended into medicinal material thick paste made from (1), is stirred, cooling is then placed and keeps plaster in 62-65 DEG C of temperature；(6) it spreads out Apply: by lotion, 8 grams of taken amount, booth are stored in packing box in the circle in kraft back, painting diameter 6cm, folding, store while hot In a cool and dry place to obtain the final product.
2. the preparation method of black plaster as described in claim 1, which is characterized in that the vegetable oil is sesame oil.
CN201811181296.6A 2018-10-11 2018-10-11 A kind of preparation method of children's disperse accumulation note black plaster Withdrawn CN108939017A (en)

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Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104352811A (en) * 2014-10-28 2015-02-18 青岛市市立医院 Plaster for curing bone injury and preparation method thereof

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104352811A (en) * 2014-10-28 2015-02-18 青岛市市立医院 Plaster for curing bone injury and preparation method thereof

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
王运利: "《现代中医收藏方典》", 30 November 2011, 陕西科学技术出版社 *

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